C Y Ang

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi Determination of hyperforin in human plasma using solid-phase extraction and high-performance liquid chromatography with ultraviolet detection
    Yanyan Cui
    Division of Chemistry, National Center for Toxicological Research, US Food and Drug Administration, HFT-230, 3900 NCTR Road, Jefferson, AR 72079, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 780:129-35. 2002
  2. ncbi Liquid chromatographic analysis of incurred amoxicillin residues in catfish muscle following oral administration of the drug
    C Y Ang
    Division of Chemistry, National Center for Toxicological Research, U S Food and Drug Administration, 3900 NCTR Road, Jefferson, Arkansas 72079, USA
    J Agric Food Chem 48:1673-7. 2000
  3. ncbi Instability of St. John's wort (Hypericum perforatum L.) and degradation of hyperforin in aqueous solutions and functional beverage
    Catharina Y W Ang
    National Center for Toxicological Research, U S Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    J Agric Food Chem 52:6156-64. 2004
  4. ncbi Determination of St. John's wort components in dietary supplements and functional foods by liquid chromatography
    Catharina Y W Ang
    U S Food and Drug Administration, National Center for Toxicological Research, Division of Chemistry, Jefferson, AR 72079, USA
    J AOAC Int 85:1360-9. 2002
  5. ncbi Evaluation of major active components in St. John's Wort dietary supplements by high-performance liquid chromatography with photodiode array detection and electrospray mass spectrometric confirmation
    F F Liu
    US Food and Drug Administration, National Center for Toxicological Research, Division of Chemistry, Jefferson, AR 72079, USA
    J Chromatogr A 888:85-92. 2000
  6. ncbi Determination of six kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standard
    Lihong Hu
    U.S. Food and Drug Administration, National Center for Toxicological Research, Division of Chemistry, HFT-230, 3900 NCTR Rd, Jefferson, AR 72079, USA
    J AOAC Int 88:16-25. 2005
  7. ncbi Liquid chromatography-mass spectrometry studies of St. John's wort methanol extraction: active constituents and their transformation
    Frances Liu
    Novartis Pharmaceuticals Corporation, East Hanover, NJ 07936, USA
    J Pharm Biomed Anal 37:303-12. 2005
  8. ncbi Sample preparation and determination of ginkgo terpene trilactones in selected beverage, snack, and dietary supplement products by liquid chromatography with evaporative light-scattering detection
    Qingyong Lang
    University of Idaho, Department of Chemistry, Moscow, ID 83843, USA
    J AOAC Int 87:815-26. 2004
  9. ncbi Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures
    Bernard J Komoroski
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Drug Metab Dispos 32:512-8. 2004
  10. ncbi In vitro metabolism of hyperforin in rat liver microsomal systems
    Yanyan Cui
    National Center for Toxicological Research, Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    Drug Metab Dispos 32:28-34. 2004

Collaborators

Detail Information

Publications16

  1. ncbi Determination of hyperforin in human plasma using solid-phase extraction and high-performance liquid chromatography with ultraviolet detection
    Yanyan Cui
    Division of Chemistry, National Center for Toxicological Research, US Food and Drug Administration, HFT-230, 3900 NCTR Road, Jefferson, AR 72079, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 780:129-35. 2002
    ..John's wort administration were analyzed. The result suggests that this method is rapid, sensitive, reproducible and capable of quantitative analysis of hyperforin plasma concentrations...
  2. ncbi Liquid chromatographic analysis of incurred amoxicillin residues in catfish muscle following oral administration of the drug
    C Y Ang
    Division of Chemistry, National Center for Toxicological Research, U S Food and Drug Administration, 3900 NCTR Road, Jefferson, Arkansas 72079, USA
    J Agric Food Chem 48:1673-7. 2000
    ..2 ng/g). An LC-MS/MS confirmatory method was developed. Confirmation of the presence of amoxicillin was demonstrated in incurred fish samples containing residues at approximately 50-300 ng/g...
  3. ncbi Instability of St. John's wort (Hypericum perforatum L.) and degradation of hyperforin in aqueous solutions and functional beverage
    Catharina Y W Ang
    National Center for Toxicological Research, U S Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    J Agric Food Chem 52:6156-64. 2004
    ..The latter was also found in the drink product containing SJW as an ingredient. Biological activities and potential quality and safety implications of these chemical changes are yet to be evaluated...
  4. ncbi Determination of St. John's wort components in dietary supplements and functional foods by liquid chromatography
    Catharina Y W Ang
    U S Food and Drug Administration, National Center for Toxicological Research, Division of Chemistry, Jefferson, AR 72079, USA
    J AOAC Int 85:1360-9. 2002
    ..The methods developed provide a useful means for the determination of St. John's wort components in dietary supplements and functional foods...
  5. ncbi Evaluation of major active components in St. John's Wort dietary supplements by high-performance liquid chromatography with photodiode array detection and electrospray mass spectrometric confirmation
    F F Liu
    US Food and Drug Administration, National Center for Toxicological Research, Division of Chemistry, Jefferson, AR 72079, USA
    J Chromatogr A 888:85-92. 2000
    ..The quantification of components was performed using an internal standard (luteolin). This method may serve as a valuable tool for the quality evaluation of St. John's Wort dietary supplement products...
  6. ncbi Determination of six kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standard
    Lihong Hu
    U.S. Food and Drug Administration, National Center for Toxicological Research, Division of Chemistry, HFT-230, 3900 NCTR Rd, Jefferson, AR 72079, USA
    J AOAC Int 88:16-25. 2005
    ..Methods developed in this study offer a simple and reproducible means for analysis of kavalactones in various matrixes of dietary products...
  7. ncbi Liquid chromatography-mass spectrometry studies of St. John's wort methanol extraction: active constituents and their transformation
    Frances Liu
    Novartis Pharmaceuticals Corporation, East Hanover, NJ 07936, USA
    J Pharm Biomed Anal 37:303-12. 2005
    ..One hyperforin transformation product was studied using LC-MS. The molecular structure was proposed on the basis of ion fragmentation patterns obtained from MS/MS studies...
  8. ncbi Sample preparation and determination of ginkgo terpene trilactones in selected beverage, snack, and dietary supplement products by liquid chromatography with evaporative light-scattering detection
    Qingyong Lang
    University of Idaho, Department of Chemistry, Moscow, ID 83843, USA
    J AOAC Int 87:815-26. 2004
    ..For most samples, the relative standard deviation was <10%. The identities of target compounds in ginkgo leaves and drink samples were confirmed by LC/electrospray ionization-tandem mass spectrometry...
  9. ncbi Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures
    Bernard J Komoroski
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Drug Metab Dispos 32:512-8. 2004
    ....
  10. ncbi In vitro metabolism of hyperforin in rat liver microsomal systems
    Yanyan Cui
    National Center for Toxicological Research, Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    Drug Metab Dispos 32:28-34. 2004
    ....
  11. ncbi Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans
    Bill J Gurley
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, 72205, USA
    Clin Pharmacol Ther 72:276-87. 2002
    ..Single-time point phenotypic metabolic ratios were used to determine whether long-term supplementation of St John's wort, garlic oil, Panax ginseng, and Ginkgo biloba affected CYP1A2, CYP2D6, CYP2E1, or CYP3A4 activity...
  12. ncbi Supercritical fluid extraction and high-performance liquid chromatographic determination of phloroglucinols in St. John's Wort (Hypericum perforatum L.)
    Yanyan Cui
    Division of Chemistry, National Center for Toxicological Research, U.S. Food and Drug Administration, HFT-230, 3900 NCTR Road, Jefferson, Arkansas 72079, USA
    J Agric Food Chem 50:2755-9. 2002
    ..A simple and sensitive HPLC method was developed for the analysis of hyperforin and adhyperforin, the major phloroglucinols, in the SFE extract of SJW...
  13. ncbi Rapid method for the determination of total 5-methyltetrahydrofolate in blood by liquid chromatography with fluorescence detection
    Wenhong Lu
    The Central Laboratory, Shantou University Medical College, Guangdong, China
    J Chromatogr B Analyt Technol Biomed Life Sci 766:331-7. 2002
    ..Application of the method to a survey of whole-blood total 5-MTHF levels of women at child-bearing age showed that the method was reliable and suitable for the determination of blood total 5-MTHF...
  14. ncbi Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba
    Bill J Gurley
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Drugs Aging 22:525-39. 2005
    ....
  15. ncbi Stability of black tea polyphenol, theaflavin, and identification of theanaphthoquinone as its major radical reaction product
    Jin-Woo Jhoo
    Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, New Jersey, 08901, USA
    J Agric Food Chem 53:6146-50. 2005
    ..Theanaphthoquinone was identified as an autoxidation product of theaflavin during its stability study in alkaline conditions...
  16. ncbi In vitro cytotoxicity of nonpolar constituents from different parts of kava plant (Piper methysticum)
    Jin Woo Jhoo
    National Center for Toxicological Research, U S Food and Drug Administration, HFT 230, 3900 NCTR Road, Jefferson, Arkansas 72079, USA
    J Agric Food Chem 54:3157-62. 2006
    ..The identity of the compound was confirmed by (1)H and (13) C NMR and MS techniques...