Shaohua Xu

Summary

Affiliation: Florida Institute of Technology
Country: USA

Publications

  1. ncbi request reprint Aggregation drives "misfolding" in protein amyloid fiber formation
    Shaohua Xu
    Biological Sciences Department, Florida Institute of Technology, Melbourne, FL 32901, USA
    Amyloid 14:119-31. 2007
  2. doi request reprint Cross-beta-sheet structure in amyloid fiber formation
    Shaohua Xu
    Department of Biological Sciences and Physics and Space Sciences, Florida Institute of Technology, Melbourne, FL 32901, USA
    J Phys Chem B 113:12447-55. 2009
  3. ncbi request reprint Chemical colloids versus biological colloids: a comparative study for the elucidation of the mechanism of protein fiber formation
    Shaohua Xu
    Florida Space Research Institute, Space Life Sciences Laboratory, Kennedy Space Center, Florida 32899, USA
    Biochemistry 44:5381-9. 2005
  4. ncbi request reprint Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations
    Erin H Norris
    Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Institute on Aging, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 280:21212-9. 2005

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Aggregation drives "misfolding" in protein amyloid fiber formation
    Shaohua Xu
    Biological Sciences Department, Florida Institute of Technology, Melbourne, FL 32901, USA
    Amyloid 14:119-31. 2007
    ..We propose that aggregation drives conformational change and that a conformational change is not essential to initiate the aggregation process...
  2. doi request reprint Cross-beta-sheet structure in amyloid fiber formation
    Shaohua Xu
    Department of Biological Sciences and Physics and Space Sciences, Florida Institute of Technology, Melbourne, FL 32901, USA
    J Phys Chem B 113:12447-55. 2009
    ..The cross alpha-sheet then evolves into the thermodynamically more stable cross beta-sheet...
  3. ncbi request reprint Chemical colloids versus biological colloids: a comparative study for the elucidation of the mechanism of protein fiber formation
    Shaohua Xu
    Florida Space Research Institute, Space Life Sciences Laboratory, Kennedy Space Center, Florida 32899, USA
    Biochemistry 44:5381-9. 2005
    ..The analysis of colloidal gold formation and of one-dimensional aggregation provides a simple model system for the elucidation of some aspects of protein fiber formation...
  4. ncbi request reprint Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations
    Erin H Norris
    Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Institute on Aging, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 280:21212-9. 2005
    ..Thus, decreased dopamine levels in substantia nigra neurons might promote alpha-syn aggregation in Parkinson's disease...