STEVEN RICHARD SMITH

Summary

Affiliation: Florida Hospital
Country: USA

Publications

  1. pmc Remodeling lipid metabolism and improving insulin responsiveness in human primary myotubes
    Lauren M Sparks
    Molecular and Experimental Endocrinology Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America
    PLoS ONE 6:e21068. 2011
  2. doi request reprint Combination therapy with naltrexone and bupropion for obesity reduces total and visceral adiposity
    S R Smith
    Translational Research Institute for Metabolism and Diabetes, Florida Hospital Burnham Institute, Winter Park, FL 32789, USA
    Diabetes Obes Metab 15:863-6. 2013
  3. pmc Sex differences in human adipose tissues - the biology of pear shape
    Kalypso Karastergiou
    Department of Medicine, Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA
    Biol Sex Differ 3:13. 2012
  4. pmc Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots
    Kalypso Karastergiou
    Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Clin Endocrinol Metab 98:362-71. 2013
  5. doi request reprint Orlistat 60 mg reduces visceral adipose tissue: a 24-week randomized, placebo-controlled, multicenter trial
    Steven R Smith
    Bioimaging, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
    Obesity (Silver Spring) 19:1796-803. 2011
  6. ncbi request reprint Multicenter, placebo-controlled trial of lorcaserin for weight management
    Steven R Smith
    Translational Research Institute for Metabolism and Diabetes, Florida Hospital and the Sanford Burnham Institute, Winter Park, FL 32789, USA
    N Engl J Med 363:245-56. 2010
  7. pmc Skeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetes
    Sudip Bajpeyi
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    J Clin Endocrinol Metab 96:1160-8. 2011

Collaborators

Detail Information

Publications8

  1. pmc Remodeling lipid metabolism and improving insulin responsiveness in human primary myotubes
    Lauren M Sparks
    Molecular and Experimental Endocrinology Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America
    PLoS ONE 6:e21068. 2011
    ..We hypothesized that activation of cAMP/PKA and calcium signaling pathways in cultured human myotubes would provide further insight into regulation of lipid storage, lipolysis, lipid oxidation and insulin responsiveness...
  2. doi request reprint Combination therapy with naltrexone and bupropion for obesity reduces total and visceral adiposity
    S R Smith
    Translational Research Institute for Metabolism and Diabetes, Florida Hospital Burnham Institute, Winter Park, FL 32789, USA
    Diabetes Obes Metab 15:863-6. 2013
    ..Reductions in body fat and VAT mass with naltrexone/bupropion were proportional with weight loss. Weight loss with naltrexone/bupropion was not associated with a greater relative reduction in lean mass than placebo or the monotherapies. ..
  3. pmc Sex differences in human adipose tissues - the biology of pear shape
    Kalypso Karastergiou
    Department of Medicine, Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA
    Biol Sex Differ 3:13. 2012
    ..We provide a brief overview of the relationship of fat distribution to metabolic health in men and women, and then focus on mechanisms underlying sex differences in adipose tissue biology...
  4. pmc Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots
    Kalypso Karastergiou
    Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Clin Endocrinol Metab 98:362-71. 2013
    ..Differences in cellular characteristics and metabolic functions of these depots have been described, but the molecular mechanisms involved are not understood...
  5. doi request reprint Orlistat 60 mg reduces visceral adipose tissue: a 24-week randomized, placebo-controlled, multicenter trial
    Steven R Smith
    Bioimaging, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
    Obesity (Silver Spring) 19:1796-803. 2011
    ..These results suggest that orlistat 60 mg may be an effective weight loss tool to reduce metabolic risk factors associated with abdominal obesity...
  6. ncbi request reprint Multicenter, placebo-controlled trial of lorcaserin for weight management
    Steven R Smith
    Translational Research Institute for Metabolism and Diabetes, Florida Hospital and the Sanford Burnham Institute, Winter Park, FL 32789, USA
    N Engl J Med 363:245-56. 2010
    ..Lorcaserin is a selective serotonin 2C receptor agonist that could be useful in reducing body weight...
  7. pmc Skeletal muscle mitochondrial capacity and insulin resistance in type 2 diabetes
    Sudip Bajpeyi
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    J Clin Endocrinol Metab 96:1160-8. 2011
    ..The objective of this study was to determine the role of maximum mitochondrial capacity on the variation in insulin sensitivity within a population of patients with type 2 diabetes mellitus (T2DM)...

Research Grants6

  1. MENOPAUSE EFFECT ON OBESITY, ENERGY BALANCE AND INSULIN
    Steven Smith; Fiscal Year: 2000
    ..is essential ... to advance our knowledge of the natural history of menopause". ..
  2. MENOPAUSE EFFECT ON OBESITY, ENERGY BALANCE AND INSULIN
    Steven Smith; Fiscal Year: 2004
    ..abstract_text> ..
  3. MENOPAUSE EFFECT ON OBESITY, ENERGY BALANCE AND INSULIN
    Steven Smith; Fiscal Year: 2005
    ..abstract_text> ..
  4. MENOPAUSE EFFECT ON OBESITY, ENERGY BALANCE AND INSULIN
    Steven Smith; Fiscal Year: 2006
    ..abstract_text> ..
  5. Skeletal Muscle Mitochondrial Adaptations to a Two-Year Caloric Restiction
    Steven Smith; Fiscal Year: 2009
    ..This protocol aims to test the hypothesis that reducing energy intake in non-overweight people will make mitochondria more efficient at producing ATP, thereby reducing oxidative stress and accumulated oxidative damage. ..
  6. Skeletal Muscle Mitochondrial Adaptations to a Two-Year Caloric Restiction
    STEVEN RICHARD SMITH; Fiscal Year: 2010
    ..This protocol aims to test the hypothesis that reducing energy intake in non-overweight people will make mitochondria more efficient at producing ATP, thereby reducing oxidative stress and accumulated oxidative damage. ..