Robert M Malow

Summary

Affiliation: Florida International University
Country: USA

Publications

  1. pmc Vorinostat positively regulates synaptic plasticity genes expression and spine density in HIV infected neurons: role of nicotine in progression of HIV-associated neurocognitive disorder
    Venkata Subba Rao Atluri
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, Miami, FL 33199, USA
    Mol Brain 7:37. 2014
  2. pmc Interactive Effects of Morphine on HIV Infection: Role in HIV-Associated Neurocognitive Disorder
    Pichili Vijaya Bhaskar Reddy
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA
    AIDS Res Treat 2012:953678. 2012
  3. pmc Magnetic nanoformulation of azidothymidine 5'-triphosphate for targeted delivery across the blood-brain barrier
    Zainulabedin M Saiyed
    Department of Immunology, College of Medicine, Florida International University, Miami, FL, USA
    Int J Nanomedicine 5:157-66. 2010
  4. pmc Human synaptic plasticity gene expression profile and dendritic spine density changes in HIV-infected human CNS cells: role in HIV-associated neurocognitive disorders (HAND)
    Venkata Subba Rao Atluri
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, USA
    PLoS ONE 8:e61399. 2013
  5. pmc Targeted brain derived neurotropic factors (BDNF) delivery across the blood-brain barrier for neuro-protection using magnetic nano carriers: an in-vitro study
    Sudheesh Pilakka-Kanthikeel
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, United States of America
    PLoS ONE 8:e62241. 2013
  6. pmc Ashwagandha (Withania somnifera) reverses β-amyloid1-42 induced toxicity in human neuronal cells: implications in HIV-associated neurocognitive disorders (HAND)
    Kesava Rao Venkata Kurapati
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Modesto A Maidique Campus, Miami, Florida, United States of America
    PLoS ONE 8:e77624. 2013
  7. pmc Cocaine enhances HIV-1 infectivity in monocyte derived dendritic cells by suppressing microRNA-155
    Jessica Napuri
    Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, United States of America
    PLoS ONE 8:e83682. 2013
  8. pmc HIV infection and drugs of abuse: role of acute phase proteins
    Thangavel Samikkannu
    Department of Immunology, Institute of Neuroimmune Pharmacology, College of Medicine, Florida International University, Miami, FL 33199, USA
    J Neuroinflammation 10:113. 2013
  9. doi request reprint Silicone nanoparticles do not induce immune responses by naïve human peripheral blood mononuclear cells: implications in breast implants
    Narayanan Nair
    Department of Surgery, Synergy Medical Center, Institute of Neuro Immune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Saginaw, Mich 33199, USA
    Plast Reconstr Surg 130:128e-137e. 2012
  10. ncbi request reprint Differential regulation of neurotoxin in HIV clades: role of cocaine and methamphetamine
    Madhavan P N Nair
    Department of Immunology, Institute of Neuroimmune Pharmacology, College of Medicine, Florida International University, University Park, 11200 S W 8th Street, Miami, FL 33199, USA
    Curr HIV Res 10:429-34. 2012

Collaborators

Detail Information

Publications24

  1. pmc Vorinostat positively regulates synaptic plasticity genes expression and spine density in HIV infected neurons: role of nicotine in progression of HIV-associated neurocognitive disorder
    Venkata Subba Rao Atluri
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, Miami, FL 33199, USA
    Mol Brain 7:37. 2014
    ..Cognitive impairment in heavy cigarette smokers has been well reported. However, the synergistic effects of nicotine and HIV infection and the underlying mechanisms in the development of HAND are unknown...
  2. pmc Interactive Effects of Morphine on HIV Infection: Role in HIV-Associated Neurocognitive Disorder
    Pichili Vijaya Bhaskar Reddy
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA
    AIDS Res Treat 2012:953678. 2012
    ..Better understanding on the role of morphine in HIV infection and mechanisms through which morphine mediates its effects may help in devising novel therapeutic strategies against HIV-1 infection in opiate using HIV-infected population...
  3. pmc Magnetic nanoformulation of azidothymidine 5'-triphosphate for targeted delivery across the blood-brain barrier
    Zainulabedin M Saiyed
    Department of Immunology, College of Medicine, Florida International University, Miami, FL, USA
    Int J Nanomedicine 5:157-66. 2010
    ....
  4. pmc Human synaptic plasticity gene expression profile and dendritic spine density changes in HIV-infected human CNS cells: role in HIV-associated neurocognitive disorders (HAND)
    Venkata Subba Rao Atluri
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, USA
    PLoS ONE 8:e61399. 2013
    ..In conclusion, this study suggests that down-regulation of synaptic plasticity genes, decreased dendritic spine density and induction of apoptosis in astrocytes may contribute to the severe neuropathogenesis in clade B infection...
  5. pmc Targeted brain derived neurotropic factors (BDNF) delivery across the blood-brain barrier for neuro-protection using magnetic nano carriers: an in-vitro study
    Sudheesh Pilakka-Kanthikeel
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, United States of America
    PLoS ONE 8:e62241. 2013
    ..Our results suggest that the developed nanocarrier will provide a potential therapeutic approach to treat opiate addiction, protect neurotoxicity and synaptic density degeneration...
  6. pmc Ashwagandha (Withania somnifera) reverses β-amyloid1-42 induced toxicity in human neuronal cells: implications in HIV-associated neurocognitive disorders (HAND)
    Kesava Rao Venkata Kurapati
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Modesto A Maidique Campus, Miami, Florida, United States of America
    PLoS ONE 8:e77624. 2013
    ....
  7. pmc Cocaine enhances HIV-1 infectivity in monocyte derived dendritic cells by suppressing microRNA-155
    Jessica Napuri
    Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, United States of America
    PLoS ONE 8:e83682. 2013
    ..Our findings could lead to the development of novel miRNA-based therapeutic strategies targeting HIV infected cocaine abusers. ..
  8. pmc HIV infection and drugs of abuse: role of acute phase proteins
    Thangavel Samikkannu
    Department of Immunology, Institute of Neuroimmune Pharmacology, College of Medicine, Florida International University, Miami, FL 33199, USA
    J Neuroinflammation 10:113. 2013
    ..Acute phase proteins such as C-reactive protein (CRP) and serum amyloid A (SAA) are the biomarkers of inflammation. Hence, the interactive effect of drugs of abuse with acute phase proteins in HIV-positive subjects was investigated...
  9. doi request reprint Silicone nanoparticles do not induce immune responses by naïve human peripheral blood mononuclear cells: implications in breast implants
    Narayanan Nair
    Department of Surgery, Synergy Medical Center, Institute of Neuro Immune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Saginaw, Mich 33199, USA
    Plast Reconstr Surg 130:128e-137e. 2012
    ..The authors hypothesize that immune responses induced by in vivo use of silicone materials can be reduced or eliminated by the use of nanosilicone...
  10. ncbi request reprint Differential regulation of neurotoxin in HIV clades: role of cocaine and methamphetamine
    Madhavan P N Nair
    Department of Immunology, Institute of Neuroimmune Pharmacology, College of Medicine, Florida International University, University Park, 11200 S W 8th Street, Miami, FL 33199, USA
    Curr HIV Res 10:429-34. 2012
    ....
  11. pmc Methamphetamine enhances HIV-1 infectivity in monocyte derived dendritic cells
    Madhavan P N Nair
    Department of Immunology, College of Medicine, Florida International University, Miami, FL 33155, USA
    J Neuroimmune Pharmacol 4:129-39. 2009
    ....
  12. pmc Effect of methamphetamine on expression of HIV coreceptors and CC-chemokines by dendritic cells
    Madhavan P N Nair
    Department of Immunology, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA
    Life Sci 88:987-94. 2011
    ..DC-SIGN present on dendritic cells is the first molecule that facilitates HIV-1 infection independent of CD4 or HIV coreceptors...
  13. pmc Post-traumatic stress disorder symptomatology and alcohol use among HIV-seropositive adults in Haiti
    Jessy G Devieux
    a Department of Health Promotion and Disease Prevention, Robert Stempel College of Public Health and Social Work, Florida International University, North Miami, FL, USA
    AIDS Care 25:1210-8. 2013
    ..49, [CI = 1.15, 1.92]). Following a natural disaster, it is important to address trauma-related mental health needs of PLWH - particularly women and individuals who abuse alcohol...
  14. doi request reprint Neurological function, information-motivation-behavioral skills factors, and risk behaviors among HIV-positive alcohol users
    Robert M Malow
    Department of Health Promotion and Disease Prevention, Robert Stempel College of Public Health and Social Work, Florida International University, Biscayne Bay Campus, 3000 N E 151st Street, ACI 260, North Miami, FL, 33181, USA
    AIDS Behav 16:2297-308. 2012
    ..Future interventions geared toward HIV+ adults who use alcohol should take into consideration HIV-related and age-related neurological functioning which may impede the facilitation of safe sex behaviors...
  15. pmc Low cholesterol? Don't brag yet ... hypocholesterolemia blunts HAART effectiveness: a longitudinal study
    Maria Jose Miguez
    Institute of Neuroimmune Pharmacology, Florida International University College of Medicine, Miami, USA
    J Int AIDS Soc 13:25. 2010
    ..In vitro studies suggest that reducing cholesterol inhibits HIV replication. However, this effect may not hold in vivo, where other factors, such as cholesterol's immunomodulatory properties, may interact...
  16. pmc Cognitive behavioral HIV risk reduction in those receiving psychiatric treatment: a clinical trial
    Robert M Malow
    Florida International University, Biscayne Bay Campus, 3000 NE 151 St, AC1 260, Miami, FL 33191, USA
    AIDS Behav 16:1192-202. 2012
    ..However, meaningful changes in critical risk reduction skills and intentions may require a more focused intervention and may vary by gender...
  17. ncbi request reprint Haitian adolescent personality clusters and their problem area correlates
    Robert C McMahon
    Department of Educational and Psychological Studies, University of Miami, Miami, FL, USA
    J Immigr Minor Health 15:448-52. 2013
    ..A confident/extraverted/conforming cluster subgroup revealed few problems and appears to reflect a protective style...
  18. doi request reprint Knowledge, attitudes, and behaviors among a sample of HIV-positive and HIV-negative females visiting an urban VCT center in Haiti
    Jessy G Devieux
    Florida International University, AIDS Prevention Program, Stempel School of Public Health, 3000 NE 151st Street, ACI 260, North Miami, FL 33181, USA
    J Health Care Poor Underserved 20:554-68. 2009
    ..Addressing gaps in knowledge and behavior and reducing the risky behaviors of HIV-positive individuals are important directions for future programs...
  19. pmc US Latina age of sexual debut: long-term associations and implications for HIV and drug abuse prevention
    Frank R Dillon
    Center for Research on US Latino HIV AIDS and Drug Abuse, Florida International University, 11200 SW 8th St, Miami, FL 33199, USA
    AIDS Care 22:431-40. 2010
    ..Implications for HIV/AIDS and drug abuse clinical services and future research with US Latina populations are discussed...
  20. doi request reprint The growing cohort of seniors with HIV/AIDS: changing the scope of Medicare Part D
    Paul J Flaer
    Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA
    AIDS Care 22:903-8. 2010
    ..HIV/AIDS treatment in the present day requires a highly accessible medication provision program that is only now beginning to evolve as Medicare Part D...
  21. pmc Disclosure of their HIV status to infected children: a review of the literature
    María C Pinzón-Iregui
    Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL 33199, USA
    J Trop Pediatr 59:84-9. 2013
    ..Only one article described and evaluated a disclosure process. Despite recommendations, most HIV-infected children worldwide do not know their status. Disclosure strategies addressing caregiver concerns are urgently needed...
  22. pmc The influence of different types of alcoholic beverages on disrupting highly active antiretroviral treatment (HAART) outcome
    Maria Jose Miguez-Burbano
    Florida International University, 13313 Kingsbury Drive, Wellington, FL 33414, USA
    Alcohol Alcohol 44:366-71. 2009
    ..Discrepant findings may be related to confounding variables, including gender, patterns of alcohol abuse and type of alcohol beverage beyond the amount consumed...
  23. pmc Effects of a culturally adapted HIV prevention intervention in Haitian youth
    Robert M Malow
    Department of Health Promotion and Disease Prevention, Stempel School of Public Health, Florida International University, Miami, USA
    J Assoc Nurses AIDS Care 20:110-21. 2009
    ....
  24. doi request reprint The role of alcohol on platelets, thymus and cognitive performance among HIV-infected subjects: are they related?
    Maria Jose Miguez-Burbano
    Department of Epidemiology and Public Health, Florida International University, Miami, FL, USA
    Platelets 20:260-7. 2009
    ..06). Thymus volume and platelet counts were negatively affected by alcohol and were predictors of cognitive performance and improvements after HAART. These results could have important clinical and therapeutic implications...

Research Grants33

  1. Cocaine/Immuno and Neuropathogenesis of HIV-1 Infection
    Madhavan Nair; Fiscal Year: 2007
    ..These studies may lead to novel anti-HIV therapies such as targeting the CD4 independent, virus attachment receptor, DC-SIGN, or devising inhibitors of TDO and DC-SIGN or stimulating costimulatory molecules. ..
  2. HEROIN AIDS ENCEPHALOPATHY--NEUROPATHOGENESIS MECHANISMS
    Madhavan Nair; Fiscal Year: 2005
    ..Further studies will elucidate the molecular mechanisms underlying the immuno- and neuropathogenic effects of heroin use in HIV-l infection, and may yield novel therapies for the treatment of heroin using, HIV-infected patients. ..
  3. Polydrug Nanocarrier to Treat Opiate Addiction and HIV Disease
    Madhavan Nair; Fiscal Year: 2009
    ....
  4. Immunopathogenesis of HIV-1 Infection: Role of Methamphetamine
    Madhavan Nair; Fiscal Year: 2007
    ....
  5. Immunopathogenesis of HIV-1 Infection: Role of Methamphetamine
    Madhavan Nair; Fiscal Year: 2006
    ....
  6. Cocaine/Immuno and Neuropathogenesis of HIV-1 Infection
    Madhavan Nair; Fiscal Year: 2006
    ..These studies may lead to novel anti-HIV therapies such as targeting the CD4 independent, virus attachment receptor, DC-SIGN, or devising inhibitors of TDO and DC-SIGN or stimulating costimulatory molecules. ..
  7. AIDS encephalopathy and HIV disease: role of opioids
    Madhavan Nair; Fiscal Year: 2006
    ..abstract_text> ..
  8. Immunopathogenesis of HIV-1 Infection: Role of Methamphetamine
    Madhavan Nair; Fiscal Year: 2007
    ..at the top of each printed page and each continuationpage. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page 1 Description, ..
  9. Immunopathogenesis of HIV-1 Infection: Role of Methamphetamine
    Madhavan Nair; Fiscal Year: 2009
    ....
  10. Polydrug Nanocarrier to Treat Opiate Addiction and HIV Disease
    Madhavan P Nair; Fiscal Year: 2010
    ....
  11. Immunopathogenesis of HIV-1 Infection: Role of Methamphetamine
    Madhavan P Nair; Fiscal Year: 2010
    ....
  12. Cocaine/Immuno and Neuropathogenesis of HIV-1 Infection
    Madhavan Nair; Fiscal Year: 2006
    ..These studies may lead to novel anti-HIV therapies such as targeting the CD4 independent, virus attachment receptor, DC-SIGN, or devising inhibitors of TDO and DC-SIGN or stimulating costimulatory molecules. ..
  13. AIDS encephalopathy and HIV disease: role of opioids
    Madhavan Nair; Fiscal Year: 2006
    ..abstract_text> ..
  14. HEROIN AIDS ENCEPHALOPATHY--NEUROPATHOGENESIS MECHANISMS
    Madhavan Nair; Fiscal Year: 2001
    ..Further studies will elucidate the molecular mechanisms underlying the immuno- and neuropathogenic effects of heroin use in HIV-l infection, and may yield novel therapies for the treatment of heroin using, HIV-infected patients. ..
  15. HEROIN AIDS ENCEPHALOPATHY--NEUROPATHOGENESIS MECHANISMS
    Madhavan Nair; Fiscal Year: 2002
    ..Further studies will elucidate the molecular mechanisms underlying the immuno- and neuropathogenic effects of heroin use in HIV-l infection, and may yield novel therapies for the treatment of heroin using, HIV-infected patients. ..
  16. AIDS encephalopathy and HIV disease: role of opioids
    Madhavan Nair; Fiscal Year: 2002
    ..abstract_text> ..
  17. HEROIN AIDS ENCEPHALOPATHY--NEUROPATHOGENESIS MECHANISMS
    Madhavan Nair; Fiscal Year: 2003
    ..Further studies will elucidate the molecular mechanisms underlying the immuno- and neuropathogenic effects of heroin use in HIV-l infection, and may yield novel therapies for the treatment of heroin using, HIV-infected patients. ..
  18. AIDS encephalopathy and HIV disease: role of opioids
    Madhavan Nair; Fiscal Year: 2003
    ..abstract_text> ..
  19. HEROIN AIDS ENCEPHALOPATHY--NEUROPATHOGENESIS MECHANISMS
    Madhavan Nair; Fiscal Year: 2004
    ..Further studies will elucidate the molecular mechanisms underlying the immuno- and neuropathogenic effects of heroin use in HIV-l infection, and may yield novel therapies for the treatment of heroin using, HIV-infected patients. ..
  20. AIDS encephalopathy and HIV disease: role of opioids
    Madhavan Nair; Fiscal Year: 2004
    ..abstract_text> ..
  21. HEROIN AIDS ENCEPHALOPATHY--NEUROPATHOGENESIS MECHANISMS
    Madhavan Nair; Fiscal Year: 2005
    ..Further studies will elucidate the molecular mechanisms underlying the immuno- and neuropathogenic effects of heroin use in HIV-l infection, and may yield novel therapies for the treatment of heroin using, HIV-infected patients. ..
  22. Cocaine/Immuno and Neuropathogenesis of HIV-1 Infection
    Madhavan Nair; Fiscal Year: 2004
    ..These studies may lead to novel anti-HIV therapies such as targeting the CD4 independent, virus attachment receptor, DC-SIGN, or devising inhibitors of TDO and DC-SIGN or stimulating costimulatory molecules. ..
  23. AIDS encephalopathy and HIV disease: role of opioids
    Madhavan Nair; Fiscal Year: 2005
    ..abstract_text> ..
  24. Cocaine/Immuno and Neuropathogenesis of HIV-1 Infection
    Madhavan Nair; Fiscal Year: 2005
    ..These studies may lead to novel anti-HIV therapies such as targeting the CD4 independent, virus attachment receptor, DC-SIGN, or devising inhibitors of TDO and DC-SIGN or stimulating costimulatory molecules. ..
  25. Mechanisms of Neuro-AIDS by HIV 1B and C Clades
    Madhavan P Nair; Fiscal Year: 2010
    ....