Richard Bertram

Summary

Affiliation: Florida State University
Country: USA

Publications

  1. ncbi request reprint Role for G protein Gbetagamma isoform specificity in synaptic signal processing: a computational study
    Richard Bertram
    Department of Mathematics and Kasha Laboratory of Biophysics, Florida State University, Tallahassee, Florida 32306, USA
    J Neurophysiol 87:2612-23. 2002
  2. ncbi request reprint A simplified model for mitochondrial ATP production
    Richard Bertram
    Department of Mathematics and Programs in Neuroscience and Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA
    J Theor Biol 243:575-86. 2006
  3. ncbi request reprint Endothelin action on pituitary lactotrophs: one receptor, many GTP-binding proteins
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Sci STKE 2006:er2. 2006
  4. doi request reprint A mathematical study of the differential effects of two SERCA isoforms on Ca2+ oscillations in pancreatic islets
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Bull Math Biol 70:1251-71. 2008
  5. doi request reprint A phantom bursting mechanism for episodic bursting
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306 4510, USA
    Bull Math Biol 70:1979-93. 2008
  6. pmc A mathematical model for the actions of activin, inhibin, and follistatin on pituitary gonadotrophs
    Richard Bertram
    Department of Mathematics and Programs in Neuroscience and Molecular Biophysics, Florida State University, Tallahassee, FL 32306 4510, USA
    Bull Math Biol 70:2211-28. 2008
  7. pmc Filtering of calcium transients by the endoplasmic reticulum in pancreatic beta-cells
    Richard Bertram
    Department of Mathematics and Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida, USA
    Biophys J 87:3775-85. 2004
  8. pmc Calcium and glycolysis mediate multiple bursting modes in pancreatic islets
    Richard Bertram
    Department of Mathematics and Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida, USA
    Biophys J 87:3074-87. 2004
  9. pmc Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets
    Richard Bertram
    Department of Mathematics and Programs in Neuroscience and Molecular Biophysics, Florida State University, Tallahassee, Florida, USA
    Biophys J 92:1544-55. 2007
  10. ncbi request reprint Endothelin action on pituitary lactotrophs: one receptor, many GTP-binding proteins
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Sci STKE 2006:pe4. 2006

Research Grants

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Role for G protein Gbetagamma isoform specificity in synaptic signal processing: a computational study
    Richard Bertram
    Department of Mathematics and Kasha Laboratory of Biophysics, Florida State University, Tallahassee, Florida 32306, USA
    J Neurophysiol 87:2612-23. 2002
    ..This allows for great synapse-to-synapse variability in the distinction between signal and noise...
  2. ncbi request reprint A simplified model for mitochondrial ATP production
    Richard Bertram
    Department of Mathematics and Programs in Neuroscience and Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA
    J Theor Biol 243:575-86. 2006
    ....
  3. ncbi request reprint Endothelin action on pituitary lactotrophs: one receptor, many GTP-binding proteins
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Sci STKE 2006:er2. 2006
    ..The initial effect is stimulatory, followed later by inhibition that persists long after the agonist has been removed. Recent research has uncovered several G protein pathways that mediate these effects...
  4. doi request reprint A mathematical study of the differential effects of two SERCA isoforms on Ca2+ oscillations in pancreatic islets
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Bull Math Biol 70:1251-71. 2008
    ..Unlike SERCA3 inhibition, we demonstrate that SERCA2b inhibition has no long-term effect on cytosolic Ca2+ oscillations unless a store-operated current is activated...
  5. doi request reprint A phantom bursting mechanism for episodic bursting
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306 4510, USA
    Bull Math Biol 70:1979-93. 2008
    ..This mechanism could account for episodic bursting produced in endocrine cells or neurons, such as pancreatic islets or gonadotropin releasing neurons of the hypothalamus...
  6. pmc A mathematical model for the actions of activin, inhibin, and follistatin on pituitary gonadotrophs
    Richard Bertram
    Department of Mathematics and Programs in Neuroscience and Molecular Biophysics, Florida State University, Tallahassee, FL 32306 4510, USA
    Bull Math Biol 70:2211-28. 2008
    ..We conclude that the actions of activin, inhibin, and follistatin are consistent with LH/FSH secretion patterns, and likely complement other factors in the production of the characteristic secretion patterns in female rats...
  7. pmc Filtering of calcium transients by the endoplasmic reticulum in pancreatic beta-cells
    Richard Bertram
    Department of Mathematics and Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida, USA
    Biophys J 87:3775-85. 2004
    ..Finally, we show that a three-compartment model that includes a subspace compartment between the ER and the plasma membrane provides the best agreement with the experimental Ca2+ data...
  8. pmc Calcium and glycolysis mediate multiple bursting modes in pancreatic islets
    Richard Bertram
    Department of Mathematics and Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida, USA
    Biophys J 87:3074-87. 2004
    ..We provide experimental support for this model prediction. Overall, the model can account for a diversity of islet behaviors described in the literature over the past 20 years...
  9. pmc Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets
    Richard Bertram
    Department of Mathematics and Programs in Neuroscience and Molecular Biophysics, Florida State University, Tallahassee, Florida, USA
    Biophys J 92:1544-55. 2007
    ..Finally, we use the model to address the recent finding that the activity of islets from some mice is uniformly fast, whereas that from islets of other mice is slow. We propose a mechanism for this dichotomy...
  10. ncbi request reprint Endothelin action on pituitary lactotrophs: one receptor, many GTP-binding proteins
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Sci STKE 2006:pe4. 2006
    ..The initial effect is stimulatory, followed later by inhibition that persists long after the agonist has been removed. Recent research has uncovered several G protein pathways that mediate these effects...
  11. pmc Electrical bursting, calcium oscillations, and synchronization of pancreatic islets
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Adv Exp Med Biol 654:261-79. 2010
    ..Disturbance of oscillations, either at the level of the individual islet or at the level of islet synchronization, is detrimental and can play a major role in type 2 diabetes...
  12. ncbi request reprint A minimal model for G protein-mediated synaptic facilitation and depression
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, Florida 32306, USA
    J Neurophysiol 90:1643-53. 2003
    ..Finally, we demonstrate that relief of G protein inhibition can contribute to paired-pulse facilitation...
  13. pmc Systemic oxytocin induces a prolactin secretory rhythm via the pelvic nerve in ovariectomized rats
    Cleyde V Helena
    Departments of Biological Science, Biomedical Research Facility, Florida State University, Tallahassee, FL, USA
    Am J Physiol Regul Integr Comp Physiol 301:R676-81. 2011
    ..In fact, OT injection failed to induce a PRL secretory rhythm in pelvic-neurectomized animals, suggesting that the integrity of the pelvic nerve is necessary for the systemic OT induction of the PRL secretory rhythm in OVX rats...
  14. pmc A mathematical model for the mating-induced prolactin rhythm of female rats
    Richard Bertram
    Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA
    Am J Physiol Endocrinol Metab 290:E573-82. 2006
    ..Finally, we consider potential targets for a rhythm-terminating factor and make predictions that may be used to determine which mechanism is operational in terminating the OT- or mating-induced PRL rhythm...
  15. pmc The rhythmic secretion of mating-induced prolactin secretion is controlled by prolactin acting centrally
    Cleyde V Helena
    Department of Biological Science, Florida State University, Tallahassee, Florida 32306 4340, USA
    Endocrinology 150:3245-51. 2009
    ..These results demonstrate that PRL acts centrally to induce the PRL rhythm and that PRL in the brain is essential for the maintenance but not for the initiation of the CS-induced rhythmic PRL surges...
  16. pmc Oxytocin action at the lactotroph is required for prolactin surges in cervically stimulated ovariectomized rats
    De nise T McKee
    Department of Biological Science, Program in Neuroscience, Florida State University, Tallahassee, FL 32306, USA
    Endocrinology 148:4649-57. 2007
    ....
  17. pmc Prolactin secretory rhythm of mated rats induced by a single injection of oxytocin
    Marcel Egli
    Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA
    Am J Physiol Endocrinol Metab 290:E566-72. 2006
    ..Mathematical modeling was used to illustrate the proposed network function. The experimental results further suggest an additional feedback mechanism in which certain hypothalamic OTergic neurons are influenced by PRL...
  18. pmc Fast-activating voltage- and calcium-dependent potassium (BK) conductance promotes bursting in pituitary cells: a dynamic clamp study
    Joel Tabak
    Department of Biological Science and Department of Mathematics and Program in Neuroscience, Florida State University, Tallahassee, Florida 32306, USA
    J Neurosci 31:16855-63. 2011
    ....
  19. pmc Correlation analysis a tool for comparing relaxation-type models to experimental data
    Maurizio Tomaiuolo
    Department of Biological Science and Program in Neuroscience, Florida State University, Tallahassee, Florida, USA
    Methods Enzymol 467:1-22. 2009
    ..Otherwise, the model must be corrected. While this tool is only one test of many required to validate a mathematical model, it is easy to implement and is noninvasive...
  20. pmc Low dose of dopamine may stimulate prolactin secretion by increasing fast potassium currents
    Joel Tabak
    Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA
    J Comput Neurosci 22:211-22. 2007
    ..Thus, the stimulatory effects of DA could be mediated by a fast K+ conductance which converts tonically spiking cells to bursters. In addition, the study illustrates that..
  21. pmc From plateau to pseudo-plateau bursting: making the transition
    Wondimu Teka
    Department of Mathematics, Florida State University, Tallahassee, USA
    Bull Math Biol 73:1292-311. 2011
    ..This suggests that the design principles for bursting in endocrine cells are just quantitative variations of those for bursting in neurons...
  22. ncbi request reprint Metabolic and electrical oscillations: partners in controlling pulsatile insulin secretion
    Richard Bertram
    Department of Mathematics and Programs in Neuroscience and Molecular Biophysics, Florida State University, Tallahassee, Florida, USA
    Am J Physiol Endocrinol Metab 293:E890-900. 2007
    ..The model, however, still lacks direct confirmation and raises new issues. In this article, we highlight both the successes of the model and the challenges that it poses for the field...
  23. pmc Variations in the response of pituitary lactotrophs to oxytocin during the rat estrous cycle
    Joel Tabak
    Department of Biological Science, Florida State University, BRF 206, Tallahassee, Florida 32306, USA
    Endocrinology 151:1806-13. 2010
    ....
  24. pmc A-type K(+) current can act as a trigger for bursting in the absence of a slow variable
    Natalia Toporikova
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Neural Comput 20:436-51. 2008
    ..To our knowledge, this is the first example of a physiologically based, single-compartmental model of bursting with no slow subsystem...
  25. pmc Mathematical modeling demonstrates how multiple slow processes can provide adjustable control of islet bursting
    Margaret Watts
    Department of Mathematics, Florida State University, Tallahassee, FL, USA
    Islets 3:320-6. 2011
    ....
  26. ncbi request reprint Mathematical aspects of protein structure determination with NMR orientational restraints
    J R Quine
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    Bull Math Biol 66:1705-30. 2004
    ..These two processes, initial model building followed by refinement, are the two crucial steps between data collection and the final atomic model...
  27. doi request reprint Electrophysiological characterization and computational models of HVC neurons in the zebra finch
    Arij Daou
    Department of Mathematics, Florida State University, Tallahassee, FL 32306 4301, USA
    J Neurophysiol 110:1227-45. 2013
    ..The result is an improved characterization of the HVC neurons responsible for song production in the songbird. ..
  28. doi request reprint A computational tool for automated large-scale analysis and measurement of bird-song syntax
    Arij Daou
    Department of Mathematics, Florida State University, USA
    J Neurosci Methods 210:147-60. 2012
    ....
  29. ncbi request reprint A calcium-based phantom bursting model for pancreatic islets
    Richard Bertram
    Department of Mathematics and Kasha Laboratory of Biophysics, Florida State University, Tallahassee, Florida 32306, USA
    Bull Math Biol 66:1313-44. 2004
    ..Although it is not presently a complete model of all beta-cell properties, it demonstrates the design principles that we anticipate will underlie future progress in beta-cell modeling...
  30. pmc Rhythmic secretion of prolactin in rats: action of oxytocin coordinated by vasoactive intestinal polypeptide of suprachiasmatic nucleus origin
    Marcel Egli
    Department of Biological Sciecne, Florida State University, Tallahassee, Florida 32306 4340, USA
    Endocrinology 145:3386-94. 2004
    ..This hypothesis is illustrated with a mathematical model...
  31. pmc Quantifying the relative contributions of divisive and subtractive feedback to rhythm generation
    Joel Tabak
    Department of Biological Sciences, Florida State University, Tallahassee, Florida, USA
    PLoS Comput Biol 7:e1001124. 2011
    ..However, only the subtractive process plays a major role in setting the duration of the silent phase. This computational method can be used to analyze the role of negative feedback processes in a wide range of biological rhythms...
  32. pmc Synchronization of mouse islets of Langerhans by glucose waveforms
    Xinyu Zhang
    Department of Chemistry and Biochemistry, Florida State University, Tallahassee, 32306, USA
    Am J Physiol Endocrinol Metab 301:E742-7. 2011
    ....
  33. pmc Slow variable dominance and phase resetting in phantom bursting
    Margaret Watts
    Department of Mathematics, Florida State University, Tallahassee, FL, USA
    J Theor Biol 276:218-28. 2011
    ..Finally, we demonstrate two mechanisms by which phase-independent resetting of a burst can be achieved, as has been shown to occur in the electrical activity of pancreatic islets...
  34. ncbi request reprint Complex bursting in pancreatic islets: a potential glycolytic mechanism
    Keola Wierschem
    Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA
    J Theor Biol 228:513-21. 2004
    ..We show that the combined model can reproduce several complex bursting patterns from mouse islets published in the literature, and we illustrate how these complex oscillations are produced through the use of a fast/slow analysis...
  35. pmc Enzyme isoforms may increase phenotypic robustness
    Maurizio Tomaiuolo
    Department of Biological Science, Florida State University, Tallahassee, Florida 32306, USA
    Evolution 62:2884-93. 2008
    ..Thus, we show that controlling isoform proportion can be a powerful mechanism for reducing the effects of variations in the values of system parameters, increasing system robustness...
  36. pmc Mechanism for the universal pattern of activity in developing neuronal networks
    Joel Tabak
    Dept of Biological Science, BRF 206, Florida State Univ, Tallahassee, FL 32306, USA
    J Neurophysiol 103:2208-21. 2010
    ..This work further shows that networks with widely different architectures, different cell types, and different functions all operate according to the same general mechanism early in their development...
  37. pmc Dual pre-motor contribution to songbird syllable variation
    John A Thompson
    Program in Neuroscience and Department of Psychology, Florida State University, Tallahassee, Florida 32306 4301, USA
    J Neurosci 31:322-30. 2011
    ....
  38. pmc Models of electrical activity: calibration and prediction testing on the same cell
    Maurizio Tomaiuolo
    Department of Biological Science and Program in Neuroscience, Florida State University, Tallahassee, Florida, USA
    Biophys J 103:2021-32. 2012
    ..These cells are electrically active, and they display tonic spiking or bursting. We use our approach to predict parameter changes that can convert one pattern to the other...
  39. pmc Cervical stimulation activates A1 and locus coeruleus neurons that project to the paraventricular nucleus of the hypothalamus
    Maristela O Poletini
    Departamento de Fisiologia e Biofisica, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270 910, Brazil
    Brain Res Bull 88:566-73. 2012
    ....
  40. pmc Microfluidic system for generation of sinusoidal glucose waveforms for entrainment of islets of Langerhans
    Xinyu Zhang
    Department of Chemistry and Biochemistry and Program in Molecular Biophysics, Florida State University, Tallahassee, Florida 32306, USA
    Anal Chem 82:6704-11. 2010
    ..The system should be applicable to a wide range of cell types to aid understanding cellular responses to dynamically changing stimuli...
  41. pmc Negative feedback synchronizes islets of Langerhans
    Raghuram Dhumpa
    Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306
    Biophys J 106:2275-82. 2014
    ..In the intact animal, the liver can play this role of the coordinator of islet activity...
  42. ncbi request reprint Disconnection of a basal ganglia circuit in juvenile songbirds attenuates the spectral differentiation of song syllables
    Kevin C Elliott
    Department of Psychology, Florida State University, Tallahassee, Florida, 32306 4301
    Dev Neurobiol 74:574-90. 2014
    ....
  43. pmc The relationship between two fast/slow analysis techniques for bursting oscillations
    Wondimu Teka
    Department of Mathematics, Florida State University, Tallahassee, Florida 32306, USA
    Chaos 22:043117. 2012
    ..They become identical in the double singular limit in which voltage is infinitely fast and calcium is infinitely slow...
  44. doi request reprint Using phase relations to identify potential mechanisms for metabolic oscillations in isolated β-cell mitochondria
    Richard Bertram
    Department of Mathematics and Programs in Molecular Biophysics and Neuroscience, Florida State University, Tallahassee, Florida, USA
    Islets 1:87-94. 2009
    ..This analysis shows that the observed phase relation between citrate and NAD(P) places strict limits on the potential mechanism for the metabolic oscillations in isolated mitochondria that were observed by MacDonald and co-workers...
  45. pmc Interpreting frequency responses to dose-conserved pulsatile input signals in simple cell signaling motifs
    Patrick A Fletcher
    Department of Mathematics, Florida State University, Tallahasee, Florida, United States of America
    PLoS ONE 9:e95613. 2014
    ..The findings have implications for experiments aimed at studying the frequency response to pulsatile inputs, as well as for understanding how pulsatile patterns drive biological responses via feedforward signaling pathways. ..
  46. ncbi request reprint Atomic refinement with correlated solid-state NMR restraints
    Richard Bertram
    Department of Mathematics, Florida State University, Tallahassee, FL 32306 4510, USA
    J Magn Reson 163:300-9. 2003
    ..The software used to correlate dipolar coupling and chemical shift data and to set up energy functions and their derivatives for refinement, CNS-SS02, is available at our web site...
  47. pmc A statistical method for quantifying songbird phonology and syntax
    Wei Wu
    Department of Statistics, Florida State University, Tallahassee, FL 32306 4330, USA
    J Neurosci Methods 174:147-54. 2008
    ..We then apply the standard information-theoretic quantity K-L distance to measure dissimilarity in phonology across days of singing. A variant of this procedure can also be used to analyze differences in syllable syntax...
  48. pmc An improved hydrogen bond potential: impact on medium resolution protein structures
    Felcy Fabiola
    Kasha Laboratory of Biophysics, Florida State University, Tallahassee, Florida 32306 4380, USA
    Protein Sci 11:1415-23. 2002
    ..These findings highlight common misconceptions about hydrogen bonding in proteins, and provide explanations for why the explicit hydrogen bonding terms of some popular force field sets are often best switched off...
  49. ncbi request reprint Simulated-annealing real-space refinement as a tool in model building
    Andrei Korostelev
    Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306 4380, USA
    Acta Crystallogr D Biol Crystallogr 58:761-7. 2002
    ....
  50. ncbi request reprint Auditory-dependent vocal recovery in adult male zebra finches is facilitated by lesion of a forebrain pathway that includes the basal ganglia
    John A Thompson
    Program in Neuroscience, Florida State University, Tallahassee, Florida 32306 1270, USA
    J Neurosci 27:12308-20. 2007
    ..In part, auditory feedback may restore song by strengthening the VMP component of synaptic input to RA relative to the AFP component...
  51. pmc The Ca2+ dynamics of isolated mouse beta-cells and islets: implications for mathematical models
    Min Zhang
    Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond 23298, USA
    Biophys J 84:2852-70. 2003
    ..These results support our recent model and point to the important role of beta-cell electrical events in controlling [Ca(2+)](i) over diverse time scales in islets...
  52. ncbi request reprint Residual bound Ca2+ can account for the effects of Ca2+ buffers on synaptic facilitation
    Victor Matveev
    New Jersey Institute of Technology, University Heights, Newark, NJ 07102, USA
    J Neurophysiol 96:3389-97. 2006
    ..We conclude that Ca(2+) binding processes with slow unbinding times (tens to hundreds of milliseconds) constitute a viable mechanism of synaptic facilitation at some synapses and discuss the experimental evidence for such a mechanism...
  53. pmc Intra- and inter-islet synchronization of metabolically driven insulin secretion
    Morten Gram Pedersen
    Department of Mathematics, Technical University of Denmark, Kgs Lyngby, Denmark
    Biophys J 89:107-19. 2005
    ..Thus, we demonstrate how intra-islet and inter-islet synchronization of insulin oscillations may be achieved...
  54. pmc Diffusion of calcium and metabolites in pancreatic islets: killing oscillations with a pitchfork
    Krasimira Tsaneva-Atanasova
    Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biophys J 90:3434-46. 2006
    ..We suggest that these modes are generic features of square-wave bursters and relaxation oscillators coupled through either the activation or recovery variable...
  55. pmc Glucose modulates [Ca2+]i oscillations in pancreatic islets via ionic and glycolytic mechanisms
    Craig S Nunemaker
    Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA
    Biophys J 91:2082-96. 2006
    ....
  56. pmc Backbone structure of the amantadine-blocked trans-membrane domain M2 proton channel from Influenza A virus
    Jun Hu
    The National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Biophys J 92:4335-43. 2007
    ..In addition, spectra are shown of the amantadine-resistant mutant, S31N, in the presence and absence of amantadine...
  57. ncbi request reprint Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo?
    Craig S Nunemaker
    Department of Pharmacology and Toxicology, Virginia Commonwealth University, P O Box 980524, Richmond, Virginia 23298, USA
    Diabetes 54:3517-22. 2005
    ..We propose that individual mice have characteristic oscillatory [Ca2+]i patterns, which are imprinted in vivo through an unknown mechanism...

Research Grants5

  1. CRCNS:Comput./Exp.Study:Hypothal.-Pituitary Interaction
    Richard Bertram; Fiscal Year: 2004
    ..It will then lead to studies of effects of drugs of abuse on brain-pituitary function. ..
  2. CRCNS:Comput./Exp.Study:Hypothal.-Pituitary Interaction
    Richard Bertram; Fiscal Year: 2005
    ..It will then lead to studies of effects of drugs of abuse on brain-pituitary function. ..
  3. CRCNS:Comput./Exp.Study:Hypothal.-Pituitary Interaction
    Richard Bertram; Fiscal Year: 2006
    ..It will then lead to studies of effects of drugs of abuse on brain-pituitary function. ..
  4. CRCNS:Comput./Exp.Study:Hypothal.-Pituitary Interaction
    Richard Bertram; Fiscal Year: 2007
    ..It will then lead to studies of effects of drugs of abuse on brain-pituitary function. ..