Research Topics
| H A FinkSummaryCountry: USA Publications
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Publications
Sildenafil for male erectile dysfunction: a systematic review and meta-analysisHoward A Fink
Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, 1 Veterans Dr, PO Box 11G, Minneapolis, MN 55417, USA
Arch Intern Med 162:1349-60. 2002..To determine the efficacy and safety of sildenafil citrate in the treatment of male erectile dysfunction...- Disability after clinical fracture in postmenopausal women with low bone density: the fracture intervention trial (FIT)H A Fink
MD, MPH, VA Medical Center, One Veterans Drive, Box 11G, Minneapolis, MN 55417, USA
Osteoporos Int 14:69-76. 2003..Substantial disability also was reported after fractures of thoracic vertebrae, humerus, distal forearm, ankle and foot. Within fracture types, post-fracture disability was highly variable, ranging from none to more than 6 months... - Trazodone for erectile dysfunction: a systematic review and meta-analysisH A Fink
Geriatric Research Education and Clinical Center, Section of General Internal Medicine, VA Medical Center, Minneapolis, USA
BJU Int 92:441-6. 2003..To determine the efficacy and safety of trazodone in the treatment of erectile dysfunction (ED) in a meta-analysis... - Association of testosterone and estradiol deficiency with osteoporosis and rapid bone loss in older menHoward A Fink
Geriatric Research Eduction and Clinical Center, Veterans Affairs Medical Center, One Veterans Drive, Box 11G, Minneapolis, MN 55417, USA
J Clin Endocrinol Metab 91:3908-15. 2006..The clinical value of measuring testosterone and estradiol in older men with osteoporosis and of measuring bone mineral density (BMD) in older men with testosterone or estradiol deficiency is uncertain... - Association between Parkinson's disease and low bone density and falls in older men: the osteoporotic fractures in men studyHoward A Fink
Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
J Am Geriatr Soc 53:1559-64. 2005..To examine the association between Parkinson's disease (PD) and bone mineral density (BMD) and risk of falls... - What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa?Howard A Fink
Geriatric Research Education and Clinical Center, VA Medical Center, Minneapolis, Minnesota 55417, USA
J Bone Miner Res 20:1216-22. 2005..The proportion of deformities clinically diagnosed ranged from <15% for milder deformities to nearly 30% for more severe deformities... 
Renal function and rate of hip bone loss in older men: the Osteoporotic Fractures in Men StudyA Ishani
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minneapolis, MN, USA
Osteoporos Int 19:1549-56. 2008..Future randomized controlled trials should test whether interventions in this high risk population are effective in preventing bone loss and decreasing fracture incidence...- Long-term prediction of incident hip fracture risk in elderly white women: study of osteoporotic fracturesBrent C Taylor
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
J Am Geriatr Soc 52:1479-86. 2004..Clinicians should be alert to factors other than BMD that place older women at a high risk of hip fracture... - Association of Parkinson's disease with accelerated bone loss, fractures and mortality in older men: the Osteoporotic Fractures in Men (MrOS) studyH A Fink
Geriatric Research Education and Clinical Center, VA Medical Center, Minneapolis, MN, USA
Osteoporos Int 19:1277-82. 2008..1% vs. 0.4%), proportion of incident non-spine fractures (14.9% vs. 7.2%) and mortality (34.8% vs. 9.5%)... - Cost-effectiveness of bone densitometry among Caucasian women and men without a prior fracture according to age and body weightJ T Schousboe
Park Nicollet Institute, Minneapolis, MN, USA
Osteoporos Int 24:163-77. 2013..Among women aged 55-65 years and men aged 55-75 years without a prior fracture, body weight can be used to identify those for whom bone densitometry is cost-effective... - Endogenous sex steroids, weight change and rates of hip bone loss in older men: the MrOS studyK E Ensrud
Department of Medicine 111 0, VA Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
Osteoporos Int 17:1329-36. 2006..We hypothesized that among older men with weight loss, higher rates of bone loss at the hip would be observed in men with lower baseline bioavailable sex steroids or those with greater declines in these hormones... 
25-Hydroxyvitamin D levels and cognitive performance and decline in elderly menY Slinin
One Veterans Dr 111J, Minneapolis, MN 55417, USA
Neurology 74:33-41. 2010..To test the hypothesis that lower 25-hydroxyvitamin D [25(OH)D] levels are associated with a greater likelihood of cognitive impairment and risk of cognitive decline...- Association between self-reported prior wrist fractures and risk of subsequent hip and radiographic vertebral fractures in older women: a prospective studyJohn T Schousboe
Section of Rheumatology, Park Nicollet Health Services, Minneapolis, Minnesota 55416, USA
J Bone Miner Res 20:100-6. 2005..Validation of such an approach would require intervention trials in patients with prior wrist fracture... - Association between prior non-spine non-hip fractures or prevalent radiographic vertebral deformities known to be at least 10 years old and incident hip fractureJohn T Schousboe
Park Nicollet Health Services, Minneapolis, Minnesota 55416, USA
J Bone Miner Res 21:1557-64. 2006..Hip fracture risk assessment strategies incorporating prior fracture history should also consider elapsed time since those prior fractures... - A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older menKristine E Ensrud
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
J Am Geriatr Soc 57:492-8. 2009.... - Diet, fluid, or supplements for secondary prevention of nephrolithiasis: a systematic review and meta-analysis of randomized trialsHoward A Fink
Geriatric Research Education and Clinical Center, VA Medical Center, Minneapolis, MN 55417, USA
Eur Urol 56:72-80. 2009.... - Treatment interventions in nursing home residents with urinary incontinence: a systematic review of randomized trialsHoward A Fink
Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Mayo Clin Proc 83:1332-43. 2008..To determine the efficacy and safety of treatments for nursing home residents with urinary incontinence (UI)... - Neurotoxin treatments for urinary incontinence in subjects with spinal cord injury or multiple sclerosis: a systematic review of effectiveness and adverse effectsRoderick MacDonald
Center for Chronic Disease Outcomes Research, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota, 55417, USA
J Spinal Cord Med 31:157-65. 2008..The objective was to evaluate the effectiveness of neurotoxin treatments of urinary incontinence (UI) in individuals with spinal cord injury (SCI) or multiple sclerosis (MS)... - Differences in site-specific fracture risk among older women with discordant results for osteoporosis at hip and spine: study of osteoporotic fracturesHoward A Fink
Geriatric Research Education and Clinical Center, VA Medical Center, Minneapolis, MN 55417, USA
J Clin Densitom 11:250-9. 2008..Women osteoporotic only at spine would not have been identified from hip BMD measurement alone, and may have a sufficiently high fracture risk to warrant preventive treatment... - Health-related quality of life predicts future health care utilization and mortality in veterans with self-reported physician-diagnosed arthritis: the veterans arthritis quality of life studyJasvinder A Singh
Rheumatology Section, Medicine Service, VA Medical Center, Minneapolis, MN 55417, USA
Semin Arthritis Rheum 34:755-65. 2005..To investigate whether health-related quality of life (HRQOL) measures predict health care utilization and mortality in a cohort of veterans with self-reported physician-diagnosed arthritis... - Prevalence, severity, and health correlates of lower urinary tract symptoms among older men: the MrOS studyBrent C Taylor
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
Urology 68:804-9. 2006..The association of LUTS severity with poor health warrants increased clinical attention... - Botulinum toxin for treatment of urinary incontinence due to detrusor overactivity: a systematic review of effectiveness and adverse effectsR Macdonald
Minneapolis Veterans Affairs Center for Chronic Disease Outcomes Research and the Cochrane Review Group in Prostate Diseases and Urologic Cancers 111 0, Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
Spinal Cord 45:535-41. 2007..Systematic review... - Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fracturesKristine E Ensrud
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, and Department of Medicine, University of Minnesota, Minneapolis, MN 55417, USA
J Gerontol A Biol Sci Med Sci 62:744-51. 2007..However, the predictive validity of this phenotype for fracture outcomes and across risk subgroups is uncertain... - Urinary incontinence in older community-dwelling women: the role of cognitive and physical function declineAlison J Huang
Veterans Affairs Medical Center, San Francisco, and University of California San Francisco, San Francisco, California 94121, USA
Obstet Gynecol 109:909-16. 2007..To examine the association between cognitive decline, physical function decline, and urinary incontinence in older community-dwelling women... - Kidney function and cognitive performance and decline in older menYelena Slinin
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA
J Am Geriatr Soc 56:2082-8. 2008..To examine the association between kidney function and cognitive impairment and decline in elderly men... - Voluntary weight reduction in older men increases hip bone loss: the osteoporotic fractures in men studyKristine E Ensrud
Department of Medicine 111 0, Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, Minnesota 55417, USA
J Clin Endocrinol Metab 90:1998-2004. 2005..7%/yr in those with weight loss; test for trend, P < 0.001). Older men who experience weight loss have increased rates of hip bone loss, even among overweight and obese men undergoing voluntary weight reduction... - Cost-effectiveness of bone densitometry followed by treatment of osteoporosis in older menJohn T Schousboe
Rheumatology, Park Nicollet Health Services, Minneapolis, MN 55416, USA
JAMA 298:629-37. 2007..Osteoporotic fractures are common among elderly men... - Serum 25-hydroxyvitamin D levels and rate of hip bone loss in older menKristine E Ensrud
Center for Chronic Disease Outcomes Research, VA Medical Center, One Veterans Drive 111 0, Minneapolis, MN 55417, USA
J Clin Endocrinol Metab 94:2773-80. 2009..Vitamin D deficiency is common among older adults, but the association between 25-hydroxyvitamin D [25(OH)D] levels and rates of bone loss is uncertain... - A comparison of prediction models for fractures in older women: is more better?Kristine E Ensrud
Department of Medicine, Minneapolis Veterans Affairs Medical Center, MN 55417, USA
Arch Intern Med 169:2087-94. 2009..However, it is uncertain whether prediction with FRAX models is superior to that based on parsimonious models... - Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older womenKristine E Ensrud
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, General Internal Medicine, Minneapolis, MN 55417, USA
Arch Intern Med 168:382-9. 2008..Frailty, as defined by the index derived from the Cardiovascular Health Study (CHS index), predicts risk of adverse outcomes in older adults. Use of this index, however, is impractical in clinical practice... - Pelvic floor muscle training to improve urinary incontinence after radical prostatectomy: a systematic review of effectivenessRoderick MacDonald
Minneapolis Veterans Affairs Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
BJU Int 100:76-81. 2007..To evaluate the effectiveness of pelvic floor muscle training (PFMT) for treating urinary incontinence (UI) after radical prostatectomy (RP) by reviewing evidence from randomized trials... - BMD and risk of hip and nonvertebral fractures in older men: a prospective study and comparison with older womenSteven R Cummings
San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California 94107, USA
J Bone Miner Res 21:1550-6. 2006..As in women, lumbar spine BMD in men is only weakly associated with risk of hip fracture. Regardless of whether sex-specific or female reference values were used, T scores indicated different risks of fractures in men than in women... - Diuretic use and bone mineral density in older USA men: the osteoporotic fractures in men (MrOS) studyLionel S Lim
Division of Preventive and Occupational Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Age Ageing 34:504-7. 2005 - Alcohol use, physical performance, and functional limitations in older menPeggy M Cawthon
Research Institute, California Pacific Medical Center, San Francisco, California 94107, USA
J Am Geriatr Soc 55:212-20. 2007..To describe associations between recent alcohol intake, physical performance, and functional limitations in older men... - Loop diuretic use and increased rates of hip bone loss in older men: the Osteoporotic Fractures in Men StudyLionel S Lim
Department of Internal Medicine, Griffin Hospital, 130 Division St, Derby, CT 06418, USA
Arch Intern Med 168:735-40. 2008..Studies examining the association between loop diuretics and bone mineral density (BMD) are lacking, particularly those involving men... - Is antidepressant plus sildenafil a recipe for priapism?Timothy J Wilt
University of Minnesota Medical School, Twin Cities, USA
Postgrad Med 116:11-2. 2004 - Poor sleep is associated with impaired cognitive function in older women: the study of osteoporotic fracturesTerri Blackwell
San Francisco Coordinating Center and California Pacific Medical Center Research Institute, 185 Berry Street, Lobby 4, Suite 5700, San Francisco, CA 94107, USA
J Gerontol A Biol Sci Med Sci 61:405-10. 2006..The association between objectively measured sleep and cognition among community-dwelling elderly persons remains understudied. This observational, cross-sectional analysis examined this association... - Identification of vertebral fracture and non-osteoporotic short vertebral height in men: the MrOS studyLynne Ferrar
Academic Unit of Bone Metabolism, University of Sheffield, United Kingdom
J Bone Miner Res 22:1434-41. 2007..Non-osteoporotic SVH may mimic VF but is excluded in ABQ. In men, this led to discordance between ABQ and other methods, but SVH was not linked to low bone density. Exclusion of SVH could reduce false positives... - Alcohol intake and its relationship with bone mineral density, falls, and fracture risk in older menPeggy M Cawthon
Research Institute, California Pacific Medical Center, San Francisco, California 94107, USA
J Am Geriatr Soc 54:1649-57. 2006..To examine the association between alcohol intake and problem drinking history and bone mineral density (BMD), falls and fracture risk... - Predictors of non-spine fracture in elderly men: the MrOS studyCora E Lewis
University of Alabama, Birmingham, AL 35205, USA
J Bone Miner Res 22:211-9. 2007..1 years. Six clinical risk factors predicted fracture risk independent of hip BMD: tricyclic antidepressant use, previous fracture, inability to complete a narrow walk trial, falls in previous year, age > or =80 years, and depressed mood... - Women who maintain optimal cognitive function into old ageDeborah E Barnes
Department of Psychiatry, University of California at San Francisco, Scan Francisco, California, USA
J Am Geriatr Soc 55:259-64. 2007..To determine whether older women who maintain optimal cognitive function into old age differ from those who experience minor cognitive decline typically associated with normal aging... - Vision impairment and combined vision and hearing impairment predict cognitive and functional decline in older womenMichael Y Lin
Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA
J Am Geriatr Soc 52:1996-2002. 2004..Studies are needed to determine whether treatment of vision and hearing impairment can decrease the risk for cognitive and functional decline... - Physical performance and risk of hip fractures in older menPeggy Mannen Cawthon
Research Institute, California Pacific Medical Center, San Francisco, California 94107 1762, USA
J Bone Miner Res 23:1037-44. 2008..The repeated chair stands exam should be considered in clinical settings for evaluation of hip fracture risk. Concurrent poor performance on multiple physical function exams is associated with an increased risk of hip fractures...