Research Topics
| T Bruce FergusonSummaryCountry: USA Publications
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Publications
The STS National Database: current changes and challenges for the new millennium. Committee to Establish a National Database in Cardiothoracic Surgery, The Society of Thoracic SurgeonsT B Ferguson
Department of Surgery, LSU School of Medicine, New Orleans, LA 70112 2822, USA
Ann Thorac Surg 69:680-91. 2000..Since then it has grown to be the largest database of its kind in medicine. The NDB has been one of the pioneers in the analysis and reporting of risk-adjusted outcomes in cardiothoracic surgery...
The Society of Thoracic Surgeons' National Cardiac Database: provider engagement in continuous quality improvementT Bruce Ferguson
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA 70119, USA
Am Heart Hosp J 1:180-2. 2003
Continuous quality improvement in medicine: validation of a potential role for medical specialty societiesT Bruce Ferguson
Louisiana State University Cardiovascular Outcomes Research Group, New Orleans, LA 70119, USA
Am Heart Hosp J 1:264-72. 2003..This Society CQI Platform is a potential model for large-scale quality improvement efforts across all disciplines of medicine...
Invited commentaryT Bruce Ferguson
Division of Cardiothoracic and Vascular Surgery, The Brody School of Medicine at East Carolina University, 600 Moye Ave, Greenville, NC 27858-4354, USA
Ann Thorac Surg 82:1756-7. 2006
Preoperative beta-blocker use and mortality and morbidity following CABG surgery in North AmericaT Bruce Ferguson
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA 70012 2822, USA
JAMA 287:2221-7. 2002..The effect of preoperative beta-blocker therapy on coronary artery bypass graft surgery (CABG) outcomes has not been assessed...
A decade of change--risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990-1999: a report from the STS National Database Committee and the Duke Clinical Research Institute. Society of Thoracic SurgeonsT Bruce Ferguson
The Society of Thoracic Surgeons National Database Committee, Chicago, Illinois, USA
Ann Thorac Surg 73:480-9; discussion 489-90. 2002..Using this database we examined changes in the risk profile of patients undergoing isolated coronary artery bypass grafting (CABG) and their outcomes during the decade 1990 to 1999...
Use of continuous quality improvement to increase use of process measures in patients undergoing coronary artery bypass graft surgery: a randomized controlled trialT Bruce Ferguson
Department of Surgery and Cardiovascular Outcomes Research Group, Louisiana State University Health Sciences Center, New Orleans, LA 70119, USA
JAMA 290:49-56. 2003..A rigorous evaluation of continuous quality improvement (CQI) in medical practice has not been carried out on a national scale...
Robotic mitral valve repairs in 300 patients: a single-center experienceW Randolph Chitwood
Department of Cardiovascular Sciences, East Carolina Heart Institute, East Carolina University, Greenville, NC 27858, USA
J Thorac Cardiovasc Surg 136:436-41. 2008..Robotic mitral valve repair provides the least-invasive surgical approach. We report the largest single-center robotic mitral valve repair experience...
Cardiac surgery in nonagenarians and centenariansCharles R Bridges
Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA
J Am Coll Surg 197:347-56; discussion 356-7. 2003..But with careful patient selection, a majority of these patients have a lower risk of CABG-related mortality approaching that of younger patients...
Internal thoracic artery grafting in the elderly patient undergoing coronary artery bypass grafting: room for process improvement?T Bruce Ferguson
Surgery and Physiology, LSU Health Sciences Center, New Orleans, LA 70112 2822, USA
J Thorac Cardiovasc Surg 123:869-80. 2002..This study examined the use, complication risks, and operative (30-day) mortality associated with internal thoracic artery grafting in patients 75 years of age and older...
Cardiac procedures in patients with a body mass index exceeding 45: outcomes and long-term resultsG Hart Tyson
Department of Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, USA
Ann Thorac Surg 84:3-9; discussion 9. 2007..We undertook this study to evaluate outcomes in this cohort...
Use of mitral valve repair: analysis of contemporary United States experience reported to the Society of Thoracic Surgeons National Cardiac DatabaseEdward B Savage
Department of Cardiovascular Thoracic Surgery, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
Ann Thorac Surg 75:820-5. 2003..2%, 1999 to 32.0%, p < 0.0001). We examined contemporary (1999 to 2000) usage of mitral repair in the United States...
Clinical predictors of major infections after cardiac surgeryVance G Fowler
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Circulation 112:I358-65. 2005....
A decade of short-term outcomes in post cardiac surgery ventricular assist device implantation: data from the Society of Thoracic Surgeons' National Cardiac DatabaseAdrian F Hernandez
Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
Circulation 116:606-12. 2007..We examined a large national clinical database to assess trends in the incidence of post-cardiac surgery shock requiring VAD implantation, survival rates, and risk factors for mortality...
Outcomes associated with the use of secondary prevention medications after coronary artery bypass graft surgeryAbhinav Goyal
Duke Clinical Research Institute and Division of Cardiology, Duke University Medical Center, Durham, North Carolina 27710, USA
Ann Thorac Surg 83:993-1001. 2007..We investigated whether greater use of secondary prevention medications after coronary artery bypass graft surgery is associated with improved clinical outcomes...
Should coronary artery bypass graft surgery patients with mild or moderate aortic stenosis undergo concomitant aortic valve replacement? A decision analysis approach to the surgical dilemmaWilliam T Smith
Duke University Medical Center, Durham, North Carolina, USA
J Am Coll Cardiol 44:1241-7. 2004..Multiple sensitivity analyses were also performed to determine the variables that most profoundly affect outcome...
Contemporary performance of surgical ventricular restoration procedures: data from the Society of Thoracic Surgeons' National Cardiac DatabaseAdrian F Hernandez
Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
Am Heart J 152:494-9. 2006..We sought to characterize the performance of SVR nationally and describe the acute risks of mortality and major morbidity plus predictors of adverse outcomes...
Validation of European System for Cardiac Operative Risk Evaluation (EuroSCORE) in North American cardiac surgerySamer A M Nashef
Cardiothoracic Surgical Unit, Papworth Hospital, Papworth Everard, Cambridge CB3 8RE, UK
Eur J Cardiothorac Surg 22:101-5. 2002..To assess the performance of the European System for Cardiac Operative Risk Evaluation (EuroSCORE) when applied in a North American cardiac surgical population...
Validity of the Society of Thoracic Surgeons National Adult Cardiac Surgery DatabaseKarl F Welke
Ann Thorac Surg 77:1137-9. 2004
Atrial fibrillation correction surgery: lessons from the Society of Thoracic Surgeons National Cardiac DatabaseJames S Gammie
Division of Cardiac Surgery, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
Ann Thorac Surg 85:909-14. 2008..We also examined the subset of patients having mitral valve surgery to determine whether concurrent surgical AF correction procedures were associated with an increased risk of morbidity or mortality...
The Society of Thoracic Surgeons: 30-day operative mortality and morbidity risk modelsA Laurie W Shroyer
Denver Department of Veterans Affairs Medical Center, Denver, Colorado 80220, USA
Ann Thorac Surg 75:1856-64; discussion 1864-5. 2003..This study identified the preoperative risk factors associated with several complications and a composite outcome (the presence of any major morbidity or 30-day operative mortality or both)...
Comparison of cardiac surgery volumes and mortality rates between the Society of Thoracic Surgeons and Medicare databases from 1993 through 2001Karl F Welke
Division of Cardiothoracic Surgery, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
Ann Thorac Surg 84:1538-46. 2007....
Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgeryRajendra H Mehta
Duke Clinical Research Institute, Durham, NC 27715, USA
Circulation 114:2208-16; quiz 2208. 2006..Estimation of an individual patient's risk for postoperative dialysis can support informed clinical decision making and patient counseling...
Aprotinin--are there lessons learned?T Bruce Ferguson
JAMA 297:527-9. 2007
Impact of perioperative myocardial infarction on angiographic and clinical outcomes following coronary artery bypass grafting (from PRoject of Ex-vivo Vein graft ENgineering via Transfection [PREVENT] IV)James M Yau
Duke University Medical Center, Durham, North Carolina, USA
Am J Cardiol 102:546-51. 2008..Further research is needed into the prevention and treatment of perioperative MI in patients undergoing CABG...
Impact of residency status on perfusion times and outcomes for coronary artery bypass graft surgeryConstance K Haan
University of Florida College of Medicine Jacksonville, Jacksonville, Florida 32209, USA
Ann Thorac Surg 83:2103-10. 2007..Because these indicators are also thought to adversely affect operative outcome, we investigated the association between residency training status, perfusion times, and outcomes...
Revascularization for unprotected left main stem coronary artery stenosis stenting or surgeryDavid P Taggart
Department of Cardiac Surgery, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
J Am Coll Cardiol 51:885-92. 2008..We conclude that CABG should indeed remain the preferred revascularization treatment in good surgical candidates with unprotected LMS stenosis...
Impact of saphenous vein graft radiographic markers on clinical events and angiographic parametersStephen A Olenchock
Cardiothoracic Surgery Department, Tufts University School of Medicine and Caritas St Elizabeth s Medical Center, Boston, Massachusetts, USA
Ann Thorac Surg 85:520-4. 2008..The goal of the present analysis was to evaluate the association of SVG markers with clinical outcomes and graft patency...
Universal definition of myocardial infarctionKristian Thygesen
Circulation 116:2634-53. 2007
Coronary artery bypass graft failure after on-pump and off-pump coronary artery bypass: findings from PREVENT IVMitchell J Magee
Cardiopulmonary Research Science and Technology Institute, Dallas, Texas, USA
Ann Thorac Surg 85:494-9; discussion 499-500. 2008....
Off-pump techniques benefit men and women and narrow the disparity in mortality after coronary bypass graftingJohn D Puskas
Emory University School of Medicine, Atlanta, Georgia 30308, USA
Ann Thorac Surg 84:1447-54; discussion 1454-6. 2007..It is controversial whether off-pump CABG (OPCAB) alters this gender-based disparity...
The risk of valve surgery for endocarditis in patients with dialysis-dependent renal failureJ Scott Rankin
Centennial Medical Center, Nashville, TN, USA
J Heart Valve Dis 16:617-22; discussion 622. 2007..The study aim was to develop a simple risk scoring system to identify high-risk dialysis patients undergoing valve surgery for endocarditis...
Acute clopidogrel use and outcomes in patients with non-ST-segment elevation acute coronary syndromes undergoing coronary artery bypass surgeryRajendra H Mehta
Division of Cardiology and the Duke Clinical Research Institute, Durham, North Carolina 27715, USA
J Am Coll Cardiol 48:281-6. 2006....
Trends in emergency coronary artery bypass grafting after percutaneous coronary intervention, 1994-2003Constance K Haan
Division of Cardiothoracic Surgery, University of Florida Jacksonville, Jacksonville, Florida, USA
Ann Thorac Surg 81:1658-65. 2006..In the last decade, percutaneous coronary intervention (PCI) has undergone profound changes in techniques used to achieve revascularization and in patient selection. We examine trends in emergency surgical revascularization after PCI...
ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on the Management of Patients Raymond J Gibbons
J Am Coll Cardiol 41:159-68. 2003
From controlled trials to clinical practice: monitoring transmyocardial revascularization use and outcomesEric D Peterson
Duke Clinical Research Institute, Durham, North Carolina 27710, USA
J Am Coll Cardiol 42:1611-6. 2003..We also identified important risk factors for TMR and compared outcomes of TMR combined with coronary artery bypass graft surgery (TMR + CABG) versus bypass alone in patients receiving incomplete revascularization...
Procedural volume as a marker of quality for CABG surgeryEric D Peterson
Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, NC 27715, USA
JAMA 291:195-201. 2004....
Preoperative calcium-channel blockade in cardiac surgery: the good, the bad, the issuesT Bruce Ferguson
J Thorac Cardiovasc Surg 127:622-4. 2004
The Society of Thoracic Surgeons Practice GuidelinesFred H Edwards
Ann Thorac Surg 77:1140-1. 2004
Mentoring clinical trials in thoracic and cardiovascular surgery: a new role for the Society of Thoracic SurgeonsHenning A Gaissert
Division of Thoracic Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA
Ann Thorac Surg 77:1874-5. 2004
Secondary prevention after coronary artery bypass graft: a primary issue?T Bruce Ferguson
Am Heart J 147:948-9. 2004
Part II: Sealing holes in the safety netEric D Peterson
Centers for Education and Research on Therapeutics (CERTs) Coordinating Center, Duke Clinical Research Institute, Durham, NC 27705, USA
Am Heart J 147:985-90. 2004
Racial and ethnic disparities in care: the perspectives of cardiologistsNicole Lurie
RAND Corporation, 1200 S Hayes St, Arlington, VA 22202, USA
Circulation 111:1264-9. 2005..To be effective, educational efforts for physicians must consider providers' knowledge and beliefs about what causes disparities and what can be done about them...
Comparing on-pump and off-pump coronary artery bypass grafting: numerous studies but few conclusions: a scientific statement from the American Heart Association council on cardiovascular surgery and anesthesia in collaboration with the interdisciplinary wFrank W Sellke
Beth Israel Deaconess Medical Center, USA
Circulation 111:2858-64. 2005..To definitively answer the remaining questions of whether either strategy is superior and in which patients, a large-scale prospective randomized trial is required...
Intraoperative interventions: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgeryLawrence L Creswell
Division of Cardiothoracic Surgery, Washington University School of Medicine, 11155 Dunn Rd, Suite 204N, St Louis, MO 63136, USA
Chest 128:28S-35S. 2005....
The PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) trial: study rationale, design, and baseline patient characteristicsJohn H Alexander
Duke University Medical Center, Duke Clinical Research Institute, Durham, NC 27715, USA
Am Heart J 150:643-9. 2005..Edifoligide inhibits E2F, a transcription factor that activates cell-cycle genes responsible for neointimal hyperplasia...
Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trialJohn H Alexander
Duke University Medical Center, Duke Clinical Research Institute, Durham, NC 27715, USA
JAMA 294:2446-54. 2005..Edifoligide is an oligonucleotide decoy that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure...
Impact of unstable angina on outcomes of transmyocardial laser revascularization combined with coronary artery bypass graftingKeith A Horvath
National Heart, Lung, Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Ann Thorac Surg 80:2082-5. 2005..The objective of this study was to investigate the preoperative risk profile of patients undergoing TMR plus coronary artery bypass graft surgery (CABG) and to determine the impact of unstable angina on outcomes...
The evaluation of treatment when center-specific selection criteria vary with respect to patient riskElizabeth R DeLong
The Outcomes Research and Assessment Group, Duke Clinical Research Institute, Durham, North Carolina 27710, USA
Biometrics 61:942-9. 2005..An example that examines the effect of early extubation after bypass surgery is also presented...
Determinants of operative mortality in valvular heart surgeryJ Scott Rankin
Vanderbilt University, Nashville, Tenn, USA
J Thorac Cardiovasc Surg 131:547-57. 2006..The goal of this study was to evaluate risk factors for operative mortality comprehensively across the entire spectrum of cardiac valvular procedures over the past decade...
Hospital variability in length of stay after coronary artery bypass surgery: results from the Society of Thoracic Surgeon's National Cardiac DatabaseEric D Peterson
The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, North Carolina, USA
Ann Thorac Surg 74:464-73. 2002..We also sought to determine the relationship between hospitals' risk-adjusted PLOS and mortality outcomes...
