S V Faraone

Summary

Country: USA

Publications

  1. ncbi request reprint Genetic influences on attention deficit hyperactivity disorder
    S V Faraone
    Harvard Institute of Psychiatry, Epidemiology, and Genetics, Department of Psychiatry, Massachusetts Hospital Center, Harvard University, 750 Washington Street, Suite 255, South Easton, MA 02375, USA
    Curr Psychiatry Rep 2:143-6. 2000
  2. ncbi request reprint Assessing symptoms of attention deficit hyperactivity disorder in children and adults: which is more valid?
    S V Faraone
    Massachusetts General Hospital, Boston 02114, USA
    J Consult Clin Psychol 68:830-42. 2000
  3. ncbi request reprint The drug-placebo response curve: a new method for assessing drug effects in clinical trials
    S V Faraone
    The Pediatric Psychophamacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, and Harvard Medical School, Boston 02114, USA
    J Clin Psychopharmacol 20:673-9. 2000
  4. ncbi request reprint Toward guidelines for pedigree selection in genetic studies of attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston 02114, USA
    Genet Epidemiol 18:1-16. 2000
  5. ncbi request reprint Suggestive linkage of chromosome 10p to schizophrenia is not due to transmission ratio distortion
    S V Faraone
    Harvard Medical School Department of Psychiatry at the Massachusetts Mental Health Center, Boston, Massachusetts
    Am J Med Genet 88:607-8. 1999
  6. ncbi request reprint Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: a 4-year follow-up study
    S V Faraone
    Harvard Medical School Department of Psychiatry, Massachusetts Mental Health Center, South Easton 02375, USA
    J Abnorm Psychol 108:176-81. 1999
  7. ncbi request reprint Clinical correlates of ADHD in females: findings from a large group of girls ascertained from pediatric and psychiatric referral sources
    J Biederman
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    J Am Acad Child Adolesc Psychiatry 38:966-75. 1999
  8. pmc Neurocognitive impairment in unaffected siblings of youth with bipolar disorder
    A E Doyle
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Child Psychiatry Service, 55 Fruit Street, Boston, MA 02114, USA
    Psychol Med 39:1253-63. 2009
  9. ncbi request reprint Neuropsychological risk indicators for schizophrenia: a preliminary study of female relatives of schizophrenic and bipolar probands
    W S Kremen
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento 95817, USA
    Psychiatry Res 79:227-40. 1998
  10. ncbi request reprint Association of neuropsychological vulnerability markers in relatives of schizophrenic patients
    R Toomey
    Harvard Institute of Psychiatric Epidemiology and Genetics, Boston, MA, USA
    Schizophr Res 31:89-98. 1998

Detail Information

Publications66

  1. ncbi request reprint Genetic influences on attention deficit hyperactivity disorder
    S V Faraone
    Harvard Institute of Psychiatry, Epidemiology, and Genetics, Department of Psychiatry, Massachusetts Hospital Center, Harvard University, 750 Washington Street, Suite 255, South Easton, MA 02375, USA
    Curr Psychiatry Rep 2:143-6. 2000
    ..In addition, because ADHD appears to be genetically heterogeneous, more work is needed to delineate genetically homogeneous subtypes and describe the range of expression of their underlying genotypes...
  2. ncbi request reprint Assessing symptoms of attention deficit hyperactivity disorder in children and adults: which is more valid?
    S V Faraone
    Massachusetts General Hospital, Boston 02114, USA
    J Consult Clin Psychol 68:830-42. 2000
    ..They do not support the idea that parents of ADHD children are biased to report ADHD symptoms in themselves because of their exposure to an ADHD child...
  3. ncbi request reprint The drug-placebo response curve: a new method for assessing drug effects in clinical trials
    S V Faraone
    The Pediatric Psychophamacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, and Harvard Medical School, Boston 02114, USA
    J Clin Psychopharmacol 20:673-9. 2000
    ..The drug-placebo response curve provides clinically relevant information about the effect of drugs on continuous outcomes in controlled clinical trials...
  4. ncbi request reprint Toward guidelines for pedigree selection in genetic studies of attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston 02114, USA
    Genet Epidemiol 18:1-16. 2000
    ..This paper shows that these sub-phenotypes are useful for molecular genetic studies because (1) they have much higher empirical lambda values and (2) they affect a substantial minority of ADHD patients...
  5. ncbi request reprint Suggestive linkage of chromosome 10p to schizophrenia is not due to transmission ratio distortion
    S V Faraone
    Harvard Medical School Department of Psychiatry at the Massachusetts Mental Health Center, Boston, Massachusetts
    Am J Med Genet 88:607-8. 1999
    ..Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:607-608, 1999...
  6. ncbi request reprint Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: a 4-year follow-up study
    S V Faraone
    Harvard Medical School Department of Psychiatry, Massachusetts Mental Health Center, South Easton 02375, USA
    J Abnorm Psychol 108:176-81. 1999
    ..These results support the idea that neuropsychological dysfunction among relatives of patients with schizophrenia is a stable trait caused by the familial predisposition to schizophrenia...
  7. ncbi request reprint Clinical correlates of ADHD in females: findings from a large group of girls ascertained from pediatric and psychiatric referral sources
    J Biederman
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    J Am Acad Child Adolesc Psychiatry 38:966-75. 1999
    ..The aim of this study was to examine clinical correlates of ADHD in females using comprehensive assessments in multiple domains of functioning...
  8. pmc Neurocognitive impairment in unaffected siblings of youth with bipolar disorder
    A E Doyle
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Child Psychiatry Service, 55 Fruit Street, Boston, MA 02114, USA
    Psychol Med 39:1253-63. 2009
    ..The current study investigated whether these neurocognitive impairments index the familial risk underlying the diagnosis...
  9. ncbi request reprint Neuropsychological risk indicators for schizophrenia: a preliminary study of female relatives of schizophrenic and bipolar probands
    W S Kremen
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento 95817, USA
    Psychiatry Res 79:227-40. 1998
    ..Replication with a larger REL-BP sample and with male relatives is needed to evaluate the generalizability of the results...
  10. ncbi request reprint Association of neuropsychological vulnerability markers in relatives of schizophrenic patients
    R Toomey
    Harvard Institute of Psychiatric Epidemiology and Genetics, Boston, MA, USA
    Schizophr Res 31:89-98. 1998
    ..We discuss how the use of multiple risk indicators may help us better identify those relatives that carry the schizophrenia genotype...
  11. ncbi request reprint A controlled study of behavioral inhibition in children of parents with panic disorder and depression
    J F Rosenbaum
    Department of Psychiatry, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 157:2002-10. 2000
    ..Several lines of evidence suggest that behavioral inhibition is an index of anxiety proneness. The authors sought to replicate prior findings and examine the specificity of the association between behavioral inhibition and anxiety...
  12. pmc Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions
    K L Lunetta
    Department of Biostatistical Science, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Am J Hum Genet 66:605-14. 2000
    ..We apply our methods to a sample of families with attention-deficit/hyperactivity disorder and provide examples of how covariates and gene-environment and gene-gene interactions can be incorporated...
  13. ncbi request reprint Family study of girls with attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    Am J Psychiatry 157:1077-83. 2000
    ..To help fill this gap in the literature, the authors assessed the familial transmission of ADHD in families ascertained through girls...
  14. ncbi request reprint Patterns of psychopathology and dysfunction in high-risk children of parents with panic disorder and major depression
    J Biederman
    Pediatric Psychopharmacology Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 158:49-57. 2001
    ....
  15. pmc A controlled family study of children with DSM-IV bipolar-I disorder and psychiatric co-morbidity
    J Wozniak
    Clinical and Research Program in Pediatric Psychopharmacology and Adult ADHD at Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Med 40:1079-88. 2010
    ..To estimate the spectrum of familial risk for psychopathology in first-degree relatives of children with unabridged DSM-IV bipolar-I disorder (BP-I)...
  16. ncbi request reprint Further evidence of association between two NET single-nucleotide polymorphisms with ADHD
    J W Kim
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Mol Psychiatry 13:624-30. 2008
    ..This is the first time that identical alleles of NET from different studies were implicated, and thus our report provides further evidence that the NET gene is involved in the etiology of ADHD...
  17. ncbi request reprint Genetic association analysis of behavioral inhibition using candidate loci from mouse models
    J W Smoller
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Med Genet 105:226-35. 2001
    ..This study illustrates the potential utility of using candidate genes derived from mouse models to dissect the genetic basis of BI, a possible intermediate phenotype for panic and phobic disorders...
  18. pmc Whole-genome association study of bipolar disorder
    P Sklar
    Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA
    Mol Psychiatry 13:558-69. 2008
    ..Given the heritability of BP disorder, the lack of agreement between studies emphasizes that susceptibility alleles are likely to be modest in effect size and require even larger samples for detection...
  19. ncbi request reprint Intelligence quotient and neuropsychological profiles in patients with schizophrenia and in normal volunteers
    W S Kremen
    Department of Psychiatry, University of California, Davis School of Medicine, 2516 Stockton Boulevard, Sacramento, CA 95817, USA
    Biol Psychiatry 50:453-62. 2001
    ..The results strengthen the argument that neurocognitive deficits are core deficits of schizophrenic illness...
  20. ncbi request reprint Learning disabilities and executive dysfunction in boys with attention-deficit/hyperactivity disorder
    L J Seidman
    Department of Psychiatry, Harvard Medical School at Massachusetts General Hospital, Boston 02114, USA
    Neuropsychology 15:544-56. 2001
    ..These data indicate that comorbid LD, especially arithmetic disability, significantly increases the severity of executive function impairment in ADHD...
  21. ncbi request reprint Social impairment in girls with ADHD: patterns, gender comparisons, and correlates
    R W Greene
    Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston 02114, USA
    J Am Acad Child Adolesc Psychiatry 40:704-10. 2001
    ....
  22. ncbi request reprint Diagnostic accuracy and linkage analysis: how useful are schizophrenia spectrum phenotypes?
    S V Faraone
    Harvard Medical School Department of Psychiatry, Massachusetts Mental Health Center, Boston, USA
    Am J Psychiatry 152:1286-90. 1995
    ..However, most of these studies do not address a key measurement question: does the diagnostic accuracy of these spectrum classifications warrant their use in genetic linkage studies of schizophrenia?..
  23. pmc Examining the nature of the comorbidity between pediatric attention deficit/hyperactivity disorder and post-traumatic stress disorder
    J Biederman
    Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, MA 02114 3139, USA
    Acta Psychiatr Scand 128:78-87. 2013
    ....
  24. doi request reprint Deficient emotional self-regulation and pediatric attention deficit hyperactivity disorder: a family risk analysis
    J Biederman
    Clinical and Research Program in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Yawkey Center for Outpatient Care, Boston, MA 02114 3139, USA
    Psychol Med 42:639-46. 2012
    ..Family studies provide a method of clarifying the co-occurrence of clinical features, but no family studies have yet addressed ADHD and DESR in children...
  25. ncbi request reprint Systematic chart review of the pharmacologic treatment of comorbid attention deficit hyperactivity disorder in youth with bipolar disorder
    J Biederman
    Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston, USA
    J Child Adolesc Psychopharmacol 9:247-56. 1999
    ..Although TCAs can be helpful in the management of ADHD children with manic symptoms, these drugs should be used with caution since they can also have a destabilizing effect on manic symptoms...
  26. ncbi request reprint Genome scan of European-American schizophrenia pedigrees: results of the NIMH Genetics Initiative and Millennium Consortium
    S V Faraone
    Department of Psychiatry, Harvard Medical School at Massachusetts Mental Health Center, Boston, USA
    Am J Med Genet 81:290-5. 1998
    ..4, P = .0004) and its neighbor, D10S582 (NPL Z = 3.2, P = .0006)...
  27. ncbi request reprint Parsing pediatric bipolar disorder from its associated comorbidity with the disruptive behavior disorders
    T J Spencer
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, Massachusetts 02114-3139, USA
    Biol Psychiatry 49:1062-70. 2001
    ..What was previously considered refractory ADHD, oppositionality, aggression, and conduct disorder may respond after mood stabilization. We review these issues in this article...
  28. ncbi request reprint Sex differences in self-reported schizotypal traits in relatives of schizophrenic probands
    W S Kremen
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento 95817, USA
    Schizophr Res 34:27-37. 1998
    ....
  29. ncbi request reprint Lack of association between parental alcohol or drug addiction and behavioral inhibition in children
    J Biederman
    Department of Psychiatry Unit of Clinical Psychopharmacology, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 158:1731-3. 2001
    ..CONCLUSIONS: These results are not consistent with the hypothesis linking behavioral inhibition to addictions...
  30. ncbi request reprint Diagnostic efficiency of neuropsychological test scores for discriminating boys with and without attention deficit-hyperactivity disorder
    A E Doyle
    Department of Psychiatry, Harvard Medical School at Massachusetts General Hospital, Boston 02114, USA
    J Consult Clin Psychol 68:477-88. 2000
    ..The prognostic implications of variable neuropsychological deficits in children with ADHD require further investigation...
  31. ncbi request reprint Poor perception of nonverbal social-emotional cues in relatives of schizophrenic patients
    R Toomey
    Harvard Medical School Department of Psychiatry at the Massachusetts Mental Health Center, Boston 02301, USA
    Schizophr Res 40:121-30. 1999
    ..Further research is needed to clarify the nature of this relationship, to better characterize social perception deficits in relatives, and to determine whether these perceptual deficits are part of the genetic diathesis to schizophrenia...
  32. ncbi request reprint Separating attention deficit hyperactivity disorder and learning disabilities in girls: a familial risk analysis
    A E Doyle
    Pediatric Psychopharmacology Unit, Child Psychiatry Service, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 158:1666-72. 2001
    ....
  33. ncbi request reprint Long-term stability of the Child Behavior Checklist in a clinical sample of youth with attention deficit hyperactivity disorder
    J Biederman
    Harvard Medical School, Massachusetts General Hospital and McLean Hospital, Boston, MA, USA
    J Clin Child Psychol 30:492-502. 2001
    ..These results support the informativeness of the CBCL as a useful measure of longitudinal course in clinical samples of youth with ADHD...
  34. ncbi request reprint A family study of psychiatric comorbidity in girls and boys with attention-deficit/hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit, Child Psychiatry Service, Massachusetts General Hospital, Boston, Massachusetts 02114-3139, USA
    Biol Psychiatry 50:586-92. 2001
    ..Although this is consistent with prior work suggesting more similarities than differences in the nature of psychiatric comorbidity in ADHD boys and girls, we cannot make strong conclusions, owing to the possibility of cohort effects...
  35. doi request reprint The long-term longitudinal course of oppositional defiant disorder and conduct disorder in ADHD boys: findings from a controlled 10-year prospective longitudinal follow-up study
    J Biederman
    Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Med 38:1027-36. 2008
    ....
  36. ncbi request reprint Pharmacotherapy of attention-deficit/hyperactivity disorder reduces risk for substance use disorder
    J Biederman
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Pediatrics 104:e20. 1999
    ..To assess the risk for substance use disorders (SUD) associated with previous exposure to psychotropic medication in a longitudinal study of boys with attention-deficit/hyperactivity disorder (ADHD)...
  37. ncbi request reprint The paradox of normal neuropsychological function in schizophrenia
    W S Kremen
    Department of Psychiatry, University of California, Davis, School of Medicine, 4430 V Street, Sacramento, California 95817, USA
    J Abnorm Psychol 109:743-52. 2000
    ..Our results favor the view that even neuropsychologically normal schizophrenia patients have compromised cognitive function relative to their presumed expected or premorbid level of intellectual ability...
  38. ncbi request reprint Heterogeneity of childhood conduct disorder: further evidence of a subtype of conduct disorder linked to bipolar disorder
    J Wozniak
    Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Affect Disord 64:121-31. 2001
    ..Furthermore, they suggest that the comorbid condition of CD+BPD may be a distinct nosological entity. This suggests that clinicians treating CD or BPD children should consider the treatment implications of this comorbid condition...
  39. ncbi request reprint The effects of increasing resource demand on vigilance performance in adults with schizophrenia or developmental attentional/learning disorders: a preliminary study
    L J Seidman
    Harvard Medical School Department of Psychiatry, Massachusetts Mental Health Center, Boston 02115, USA
    Schizophr Res 34:101-12. 1998
    ..Further study comparing schizophrenic patients with patients who have other neuropsychiatric disorders, controlling for severity of illness, is required to determine the specificity of this deficit in schizophrenia...
  40. ncbi request reprint Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type
    J Biederman
    Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 157:816-8. 2000
    ..Symptom decline in attention deficit hyperactivity disorder (ADHD) was examined with different definitions of remission...
  41. ncbi request reprint The genetics of schizophrenia
    M T Tsuang
    Harvard Medical School, Department of Psychiatry at the Massachusetts Mental Health Center, 74 Fenwood Road, Boston, MA 02115, USA
    Curr Psychiatry Rep 1:20-4. 1999
    ..The potential importance of schizotaxia, or similar concepts, for use in genetic studies, is discussed...
  42. pmc The lifetime impact of attention deficit hyperactivity disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
    S Bernardi
    Department of Psychiatry, Columbia University New York State Psychiatric Institute, New York, NY, USA
    Psychol Med 42:875-87. 2012
    ....
  43. ncbi request reprint Further evidence of association between behavioral inhibition and social anxiety in children
    J Biederman
    Department of Psychiatry, Massachusetts General Hospital, Boston, 02114, USA
    Am J Psychiatry 158:1673-9. 2001
    ..1 versus 50.8). CONCLUSIONS: This study adds to the growing literature suggesting an association between behavioral inhibition and social anxiety disorder and an inverse relationship between inhibition and disruptive behavior disorders...
  44. ncbi request reprint Evidence for an association of the dopamine D5 receptor gene on age at onset of attention deficit hyperactivity disorder
    J Lasky-Su
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Ann Hum Genet 71:648-59. 2007
    ..Although definitive conclusions await independent replication, these results suggest that a variant in DRD5 may affect age at onset for ADHD...
  45. ncbi request reprint Cortical abnormalities in schizophrenia identified by structural magnetic resonance imaging
    J M Goldstein
    Department of Psychiatry, Institute of Psychiatric Epidemiology and Genetics, Massachusetts Mental Health Center, Boston 02115, USA
    Arch Gen Psychiatry 56:537-47. 1999
    ..We hypothesized, based on previous empirical and theoretical work, that dorsolateral prefrontal and paralimbic cortices would be significantly volumetrically reduced in patients with schizophrenia compared with normal controls...
  46. ncbi request reprint Methodological complexities in the diagnosis of major depression in youth: an analysis of mother and youth self-reports
    E B Braaten
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    J Child Adolesc Psychopharmacol 11:395-407. 2001
    ..To this end we evaluated whether morbidity and functional correlates on the diagnosis of MDD in youth vary by informant source...
  47. ncbi request reprint Evidence for the multigenic inheritance of schizophrenia
    R Freedman
    Department of Psychiatry, Denver VA Medical Center and University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Med Genet 105:794-800. 2001
    ....
  48. ncbi request reprint Meta-analysis of the association between the 7-repeat allele of the dopamine D(4) receptor gene and attention deficit hyperactivity disorder
    S V Faraone
    Pediatric Psychopharmacology Unit, Child Psychiatric Services, Massachusetts General Hospital, Boston 02114, USA
    Am J Psychiatry 158:1052-7. 2001
    ..Although several studies have shown an association between ADHD and the 7-repeat allele of the dopamine D(4) receptor gene (DRD4), several studies have not. Thus, the status of the ADHD-DRD4 association is uncertain...
  49. ncbi request reprint Patterns of remission and symptom decline in conduct disorder: a four-year prospective study of an ADHD sample
    J Biederman
    Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, USA
    J Am Acad Child Adolesc Psychiatry 40:290-8. 2001
    ..To evaluate systematically the longitudinal course of conduct disorder (CD) in a sample of youths with attention-deficit hyperactivity disorder (ADHD) to determine the effects of a persistent course on outcome...
  50. ncbi request reprint Therapeutic dilemmas in the pharmacotherapy of bipolar depression in the young
    J Biederman
    Child Psychiatry Service, Massachusetts General Hospital, Boston, USA
    J Child Adolesc Psychopharmacol 10:185-92. 2000
    ..Because bipolar youth commonly come to clinical practice with depression, these results underscore the importance of assessing a lifetime history of bipolar disorder in making treatment decisions in depressed youth...
  51. ncbi request reprint Attention deficit hyperactivity disorder with bipolar disorder in girls: further evidence for a familial subtype?
    S V Faraone
    Pediatric Psychopharmacology Unit, Psychiatry Service, ACC 725, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
    J Affect Disord 64:19-26. 2001
    ..To clarify the nosologic status of girls with attention deficit hyperactivity disorder (ADHD) who also satisfy diagnostic criteria for bipolar disorder (BPD)...
  52. pmc Personality traits among ADHD adults: implications of late-onset and subthreshold diagnoses
    S V Faraone
    Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Psychol Med 39:685-93. 2009
    ..Previous work has assessed the validity of such diagnoses based on psychiatric co-morbidity, family history and neuropsychological functions but none of these studies have used personality as a validation criterion...
  53. ncbi request reprint Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging
    J M Goldstein
    Harvard Medical School Department of Psychiatry at Massachusetts Mental Health Center, Boston, MA 02115, USA
    Cereb Cortex 11:490-7. 2001
    ..These findings have implications for developmental studies that would directly test hypotheses about mechanisms relating sex steroid hormones to sexual dimorphisms in humans...
  54. ncbi request reprint Efficacy of Adderall and methylphenidate in attention deficit hyperactivity disorder: a reanalysis using drug-placebo and drug-drug response curve methodology
    S V Faraone
    Pediatric Psychopharmacology Unit, Child Psychiatry Services, Massachusetts General Hospital, Boston 02114, USA
    J Child Adolesc Psychopharmacol 11:171-80. 2001
    ..They further suggest that, compared with the Conners Teacher Rating Scale, the Clinical Global Impressions scale may be more sensitive to improvements at the "well end" of the spectrum of functioning...
  55. ncbi request reprint Concurrent validation of schizotaxia: a pilot study
    W S Stone
    Department of Psychiatry at Massachusetts Mental Health Center, Harvard Medical School, 74 Fenwood Road, Boston, MA 02115, USA
    Biol Psychiatry 50:434-40. 2001
    ....
  56. pmc Predictors of persistence in girls with attention deficit hyperactivity disorder: results from an 11-year controlled follow-up study
    J Biederman
    Pediatric Psychopharmacology Research Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Acta Psychiatr Scand 125:147-56. 2012
    ..This study sought to examine the age-dependent persistence of attention deficit hyperactivity disorder (ADHD) and its predictors in a large sample of girls with and without ADHD followed prospectively for 11 years into young adulthood...
  57. ncbi request reprint Towards further understanding of the co-morbidity between attention deficit hyperactivity disorder and bipolar disorder: a MRI study of brain volumes
    J Biederman
    Clinical and Research Program in Pediatric Psychopharmacology, Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Med 38:1045-56. 2008
    ....
  58. ncbi request reprint Toward reformulating the diagnosis of schizophrenia
    M T Tsuang
    Harvard Medical School Department of Psychiatry, Massachusetts Mental Health Center, Boston 02115, USA
    Am J Psychiatry 157:1041-50. 2000
    ..The authors then discuss alternative conceptions of schizophrenia that take into account recent data concerning its genetic and neurodevelopmental origins and its pathophysiological substrates...
  59. ncbi request reprint Stability of executive function deficits into young adult years: a prospective longitudinal follow-up study of grown up males with ADHD
    J Biederman
    Pediatric Psychopharmacology Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Acta Psychiatr Scand 116:129-36. 2007
    ..Although individuals with attention deficit-hyperactivity disorder (ADHD) commonly exhibit deficits in executive functions that greatly increase the morbidity of the disorder, all available information on the subject is cross sectional...
  60. ncbi request reprint Investigation of variation in SNAP-25 and ADHD and relationship to co-morbid major depressive disorder
    J W Kim
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Med Genet B Neuropsychiatr Genet 144:781-90. 2007
    ..We further suggest that co-morbidity with MDD may enhance detection of the association between SNAP-25 and ADHD...
  61. pmc The CBCL as a screen for psychiatric comorbidity in paediatric patients with ADHD
    J Biederman
    Pediatric Psychopharmacology Research Program, Massachusetts General Hospital, Yawkey Center for Patient Care YAW 6A 6900, Boston, MA 02114, USA
    Arch Dis Child 90:1010-5. 2005
    ..It was hypothesised that specific scales of the CBCL would help identify specific comorbidities within ADHD cases in the primary care setting...
  62. ncbi request reprint Meta-analysis identifies an association between the dopamine D2 receptor gene and schizophrenia
    S J Glatt
    Department of Psychiatry, Harvard Medical School at Massachusetts Mental Health Center, Boston, MA 02115, USA
    Mol Psychiatry 8:911-5. 2003
    ..Although more family-based studies are needed to confirm this relation, our results provide strong evidence that DRD2 influences susceptibility to schizophrenia...
  63. ncbi request reprint Genes, environment and schizophrenia
    M T Tsuang
    Harvard Medical School, Department of Psychiatry at Massachusetts Mental Health Center, 74 Fenwood Road, Boston, MA 02115, USA
    Br J Psychiatry Suppl 40:s18-24. 2001
    ..Nevertheless, it remains clear that environmental factors both add to and interact with genetic factors to produce the disorder...
  64. ncbi request reprint The nature and heritability of attention-deficit/hyperactivity disorder
    S V Faraone
    Clinical and Research Program in Pediatric Psychopharmacology, Child Psychiatry Service, Massachusetts General Hospital, USA
    Child Adolesc Psychiatr Clin N Am 10:299-316, viii-ix. 2001
    ..Moreover, the effectiveness of stimulants, along with animal models of hyperactivity, point to catecholamine dysregulation as at least one source of ADHD brain dysfunction...
  65. ncbi request reprint Impact of exposure to parental attention-deficit hyperactivity disorder on clinical features and dysfunction in the offspring
    J Biederman
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    Psychol Med 32:817-27. 2002
    ..This study investigated the impact of exposure to parental ADHD on clinical features and dysfunction in offspring...
  66. ncbi request reprint An open-label, dose-ranging study of atomoxetine in children with attention deficit hyperactivity disorder
    T Spencer
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    J Child Adolesc Psychopharmacol 11:251-65. 2001
    ..These results support additional controlled trials of atomoxetine in cases of pediatric ADHD...