J S Mandel
Affiliation: Exponent Inc
- Paraquat and Parkinson's disease: an overview of the epidemiology and a review of two recent studiesJ S Mandel
Exponent, Inc, Menlo Park, CA 94025, United States
Regul Toxicol Pharmacol 62:385-92. 2012..Both studies are derived primarily from the Agricultural Health Study (AHS). A review and evaluation is also provided on the AHS and several additional studies of paraquat and PD...
- The effect of fecal occult-blood screening on the incidence of colorectal cancerJ S Mandel
Exponent, Menlo Park, Calif 94025, USA
N Engl J Med 343:1603-7. 2000..However, the effect of screening on the incidence of colorectal cancer remains uncertain, despite the diagnosis and removal of precancerous lesions in many persons who undergo screening...
- Cohort mortality study of employees at the Celanese plant in Pampa, TexasJack S Mandel
Exponent Health Group, Menlo Park, California 94025, USA
Am J Ind Med 43:656-61. 2003..plant through 1991 has been previously reported. This study updates that effort and presents an additional seven years of data and follow-up that provided 268 additional cohort members and 71 new deaths...
- Pesticides and prostate cancer: a review of epidemiologic studies with specific agricultural exposure informationPamela J Mink
Exponent Health Sciences Group, Exponent, Inc, Washington, DC 20036, USA
Eur J Cancer Prev 17:97-110. 2008..Existing evidence does not point to any pesticide as satisfying widely used guidelines for establishing causation: a strong, exposure-dependent and demonstrably unconfounded, unbiased association, documented in several studies...
- Implications for epidemiologic research on variation by pesticide in studies of farmers and their familiesJohn F Acquavella
Monsanto Company/A2NE, St Louis, Missouri, USA
Scand J Work Environ Health 31:105-9; discussion 63-5. 2005..These findings point to the need to validate assumptions about exposures in studies of people who are not directly involved in pesticide application...
- A mortality update of male and female capacitor workers exposed to polychlorinated biphenylsRenate D Kimbrough
J Occup Environ Med 45:271-82. 2003..These results expand on our previous observations and as before the data fail to demonstrate any causal association between occupational PCB exposure and excess cancer mortality or any other causes of death...
- Chlorpyrifos exposure in farm families: results from the farm family exposure studyBruce H Alexander
Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Expo Sci Environ Epidemiol 16:447-56. 2006..Chlorpyrifos exposure to farm family members from the observed application was largely determined by the extent of contact with the mixing, loading, and application process...
- Agreement of pesticide biomarkers between morning void and 24-h urine samples from farmers and their childrenDeanna P Scher
Environmental Health Sciences Division, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
J Expo Sci Environ Epidemiol 17:350-7. 2007..g., farm families), the pharmacokinetics of the pesticide and the timing of exposure events and urine collection must be understood when relying on single voids as a surrogate for longer time-frames of exposure...
- Gliomas and farm pesticide exposure in men: the upper midwest health studyAvima M Ruder
Division of Surveillance, Hazard Evaluations and Field Studies, The National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio 45226, USA
Arch Environ Health 59:650-7. 2004..0. No positive association of farm pesticide exposure and glioma was found. Other farm exposures may explain the excess brain cancer risk seen in previous studies...
- Lycopene intake and prostate cancer risk: effect modification by plasma antioxidants and the XRCC1 genotypeMichael Goodman
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Nutr Cancer 55:13-20. 2006..01). Although limited by small sample size, these findings indicate that the association between lycopene and prostate cancer is complex and may be modified by other antioxidants and by XRCC1 genotype...
- Biomonitoring of 2,4-dichlorophenoxyacetic acid exposure and dose in farm familiesBruce H Alexander
University of Minnesota, School of Public Health, Minneapolis, Minnesota 55455, USA
Environ Health Perspect 115:370-6. 2007..We estimated 2,4-dichlorophenoxyacetic acid (2,4-D) exposure and systemic dose in farm family members following an application of 2,4-D on their farm...
- Hypothesis: oxidative stress score as a combined measure of pro-oxidant and antioxidant exposuresMichael Goodman
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Ann Epidemiol 17:394-9. 2007..To explore the hypothesis that a combination of several risk factors acting through the same pathway may produce an overall large increase in risk even in the presence of weak associations with each individual factor...
- Folic acid for the prevention of colorectal adenomas: a randomized clinical trialBernard F Cole
Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
JAMA 297:2351-9. 2007..Laboratory and epidemiological data suggest that folic acid may have an antineoplastic effect in the large intestine...
- Counting alleles in single lesions of prostate tumors from ethnically diverse patientsAki Morikawa
Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia 30322, USA
Prostate 68:231-40. 2008..Nevertheless, it is unclear whether such disparities are due to genetic alterations that are involved in prostate cancer initiation. Here, we evaluated chromosome 8p allelic loss in a racially diverse cohort...
- Exposure misclassification in studies of agricultural pesticides: insights from biomonitoringJohn F Acquavella
Monsanto Company, Retired, St. Louis, Missouri, USA
Epidemiology 17:69-74. 2006..CONCLUSIONS: Our results demonstrate the importance of collecting type of pesticide formulation and suggest a generic exposure assessment is likely to result in appreciable exposure misclassification for many pesticides...
- Assessment of mortality in patients enrolled in a risedronate clinical trial program: a retrospective cohort studyMichael Steinbuch
Procter and Gamble Pharmaceuticals, Mason, Ohio, USA
Regul Toxicol Pharmacol 35:320-6. 2002..Follow-up mortality data in this retrospective cohort study demonstrate that treatment with risedronate has no effect on overall mortality rates...
- Biomonitoring for farm families in the farm family exposure studyJack S Mandel
Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd, NE, Atlanta, GA 30322, USA
Scand J Work Environ Health 31:98-104; discussion 63-5. 2005..The Farm Family Exposure Study was conducted to evaluate real-world pesticide exposure for farmers, spouses, and children...
- Sigmoidoscopy screening probably works, but how well is still unknownJack S Mandel
J Natl Cancer Inst 95:571-3. 2003
- Re: All-cause mortality in randomized trials of cancer screeningTimothy R Church
J Natl Cancer Inst 94:861; author reply 865-6. 2002
- Dioxin and cancer: a critical reviewPhilip Cole
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, USA
Regul Toxicol Pharmacol 38:378-88. 2003..The long-term accumulation of negative, weak, and inconsistent findings suggests that TCDD eventually will be recognized as not carcinogenic for humans...
- Glyphosate biomonitoring for farmers and their families: results from the Farm Family Exposure StudyJohn F Acquavella
Epidemiology, Monsanto Company, mail stop A2NE, 800 North Lindbergh Boulevard, St Louis, MO 63167, USA
Environ Health Perspect 112:321-6. 2004..Nonetheless, it is advisable to minimize exposure to pesticides, and this study did identify specific practices that could be modified to reduce the potential for exposure...
- Surgical margin and Gleason score as predictors of postoperative recurrence in prostate cancer with or without chromosome 8p allelic imbalanceWei Zhou
Department of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, 1365 Clifton Road NE, Atlanta, GA 30322, USA
Prostate 61:81-91. 2004..Existing pathological markers can predict disease recurrence only to a certain extent, and there is a need for more accurate predictors...
- Reproductive factors and risk of glioma in womenKui Huang
National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
Cancer Epidemiol Biomarkers Prev 13:1583-8. 2004..7; 95% confidence interval, 0.5-1.1). CONCLUSION: These results support the hypothesis that reproductive hormones play a role in the etiology of glioma among women...
- Risk of prostate cancer in a randomized clinical trial of calcium supplementationJohn A Baron
Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire, USA
Cancer Epidemiol Biomarkers Prev 14:586-9. 2005..CONCLUSION: In this randomized controlled clinical trial, there was no increase in prostate cancer risk associated with calcium supplementation and some suggestion of a protective effect...
- Gliomas and farm pesticide exposure in women: the Upper Midwest Health StudyTania Carreon
Divion of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
Environ Health Perspect 113:546-51. 2005..Results show that exposure to pesticides was not associated with an increased risk of intracranial gliomas in women. Other farm-related factors could be etiologic factors and will be discussed in future reports...
- Temporal trends and misclassification in residential 60 Hz magnetic field measurementsRobert S Banks
Division of Environmental and Occupational Health, University of Minnesota School of Public Health, Minneapolis, Minnesota, USA
Bioelectromagnetics 23:196-205. 2002..While the 2 week measurement does somewhat decrease exposure misclassification, its added intrusiveness and cost are likely to outweigh the improved precision...
- Farm Family Exposure Study: methods and recruitment practices for a biomonitoring study of pesticide exposureBeth A Baker
Regions Hospital, St Paul, Minnesota, USA
J Expo Anal Environ Epidemiol 15:491-9. 2005..CONCLUSION: The Farm Family Exposure Study should provide insights about pesticide exposure under real world conditions and thereby facilitate improved exposure assessment in epidemiologic studies of agricultural populations...