Donna M Hacek
Affiliation: Evanston Northwestern Healthcare
- Computer-assisted surveillance for detecting clonal outbreaks of nosocomial infectionDonna M Hacek
Clinical Microbiology Division, Department of Pathology and Laboratory Medicine, Evanston Northwestern Healthcare, Evanston, Illinois 60201 1718, USA
J Clin Microbiol 42:1170-5. 2004..Statistical methods applied to clinical microbiology laboratory information system data efficiently supplement infection control efforts for outbreak detection...
- Staphylococcus aureus nasal decolonization in joint replacement surgery reduces infectionDonna M Hacek
Evanston Northwestern Healthcare, Evanston, IL, USA
Clin Orthop Relat Res 466:1349-55. 2008..6%) developed SSIs for an overall rate of 0.77%. Among the 583 control patients who were not screened or decolonized, 10 (1.7%) developed S. aureus SSIs. SSIs from other organisms were 0.44% and 0.69%, respectively...
- Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitalsAri Robicsek
Evanston Northwestern Healthcare and Northwestern University Feinberg School of Medicine, Evanston, Illinois 60201, USA
Ann Intern Med 148:409-18. 2008..The effect of large-scale expanded surveillance for methicillin-resistant Staphylococcus aureus (MRSA) on health care-associated MRSA disease is not known...
- Optimization of a laboratory-developed test utilizing roche analyte-specific reagents for detection of Staphylococcus aureus, methicillin-resistant S. aureus, and vancomycin-resistant Enterococcus speciesMaitry S Mehta
Evanston Northwestern Healthcare, Evanston, Illinois 60201, USA
J Clin Microbiol 46:2377-80. 2008..The real-time PCR and culture results for S. aureus were similar. PCR had adequate sensitivity, but culture was more specific for the detection of VRE...
- Performance of the BD GeneOhm methicillin-resistant Staphylococcus aureus test before and during high-volume clinical useSuzanne M Paule
Department of Pathology and Laboratory Medicine, Evanston Northwestern Healthcare, 2650 Ridge Avenue, Evanston, IL 60201, USA
J Clin Microbiol 45:2993-8. 2007..When one is dealing with large specimen numbers, the ACP lysis method offers easier processing without negatively affecting the sensitivity or specificity of the PCR assay...
- Electronic surveillance for infectious disease trend analysis following a quality improvement interventionKari E Peterson
Department of Laboratory Medicine and Pathology, Division of Microbiology, NorthShore University Healthsystem, Evanston, Illinois 60201, USA
Infect Control Hosp Epidemiol 33:790-5. 2012..The purpose of this study was to validate electronic tools for MRSA healthcare-associated infection (HAI) trending that can replace manual medical record review...
- Significant impact of terminal room cleaning with bleach on reducing nosocomial Clostridium difficileDonna M Hacek
NorthShore University Healthsystem, Department of Pathology and Laboratory Medicine, Division of Microbiology, Evanston, IL 60201, USA
Am J Infect Control 38:350-3. 2010..In response, an intervention of terminal room cleaning with dilute bleach was instituted to decrease the amount of C difficile environmental spore contamination from patients with C difficile infection (CDI)...
- Management of a multidrug-resistant Acinetobacter baumannii outbreak in an intensive care unit using novel environmental disinfection: a 38-month reportCarlo La Forgia
Department of Medicine, University of Chicago, Evanston, IL, USA
Am J Infect Control 38:259-63. 2010..We describe the systematic investigation initiated to discover an environmental reservoir and a novel measure taken to terminate the outbreak...
- Implementation of a universal admission surveillance and decolonization program for methicillin-resistant staphylococcus aureus (MRSA) reduces the number of MRSA and total number of S. aureus isolates reported by the clinical laboratoryDonna M Hacek
NorthShore University Healthsystem, Department of Pathology and Laboratory Medicine, 2650 Ridge Avenue, Evanston, IL 60201, USA
J Clin Microbiol 47:3749-52. 2009..The decreases in the numbers of MRSA and total S. aureus clinical isolates for each year after August 2005 were highly statistically significant compared to the numbers in each of the prior 3 years (P < 0.0001)...
- Laboratory testing for Clostridium difficile infection: light at the end of the tunnelLance R Peterson
Department of Medicine, NorthShore University Healthsystem, University of Chicago, Evanston, IL, USA
Am J Clin Pathol 136:372-80. 2011..The common enzyme immunoassay tests all had sensitivity values less than 50%. Clinical laboratory professionals need to seriously consider their diagnostic testing and use the assays that perform best for the detection of CDI...
- Detection of toxigenic Clostridium difficile in stool samples by real-time polymerase chain reaction for the diagnosis of C. difficile-associated diarrheaLance R Peterson
Department of Pathology and Laboratory Medicine, Evanston Northwestern Healthcare, Evanston, IL 60201, USA
Clin Infect Dis 45:1152-60. 2007..Current laboratory testing lacks a single assay that is sensitive, specific, and rapid. The purpose of this work was to design and validate a sensitive and specific real-time polymerase chain reaction (PCR) diagnostic test for CDAD...
- Chromogenic media vs real-time PCR for nasal surveillance of methicillin-resistant Staphylococcus aureus: impact on detection of MRSA-positive personsSuzanne M Paule
Department of Pathology and Laboratory Medicine, Division of Microbiology, NorthShore University Healthsystem, Walgreen SB525, 2650 Ridge Ave, Evanston, IL 60201, USA
Am J Clin Pathol 131:532-9. 2009..There was no substantial difference in the labor required for any of the 3 approaches...
- 5 Million Lives Campaign. Case study: an MRSA intervention at Evanston Northwestern HealthcareLance R Peterson
Northwestern University, Feinberg School of Medicine, Department of Medicine and Pathology, Evanston, Illinois, USA
Jt Comm J Qual Patient Saf 33:732-8. 2007....
- Real-time detection of blaKPC in clinical samples and surveillance specimensKathy A Mangold
Pathology and Laboratory Medicine, NorthShore University Health System, 2650 Ridge Avenue, Evanston, IL 60201, USA
J Clin Microbiol 49:3338-9. 2011..The assay accurately detects KPC-containing strains with high analytical specificity and sensitivity...
- Direct detection of Staphylococcus aureus from adult and neonate nasal swab specimens using real-time polymerase chain reactionSuzanne M Paule
Division of Clinical Microbiology, Department of Pathology and Laboratory Medicine, Evanston Northwestern Healthcare, 2650 Ridge Avenue, Evanston, IL 60201, USA
J Mol Diagn 6:191-6. 2004..Real-time PCR was able to detect S. aureus in 2 hours compared to 1 to 4 days for culture and provided sensitivity equal to or greater than culture...
- Dose-ranging study to assess the application of intranasal 2% mupirocin calcium ointment to eradicate Staphylococcus aureus nasal colonizationMaitry S Mehta
NorthShore University Healthsystem, Evanston, Illinois 60201, USA
Surg Infect (Larchmt) 14:69-72. 2013..aureus from the anterior nares is twice daily for 5 d (10 doses). We performed a two-center, randomized, open-label study to compare the utility of six and 10 doses for decolonization of S. aureus...
- Three surveillance strategies for vancomycin-resistant enterococci in hospitalized patients: detection of colonization efficiency and a cost-effectiveness modelTodd A Lee
Midwest Center for Health Services and Policy Research, Hines VA Hospital, Hines, IL 60141, USA
Infect Control Hosp Epidemiol 26:39-46. 2005....
- Detection of a community infection outbreak with virtual surveillanceLance R Peterson
Lancet 362:1587-8. 2003