Ted Feldman

..The impact of improved acute results on the long-term clinical outcome for this patient group will require further study...

..Ultimately, the acceptance of femoral closure devices will depend on which device provides a simple approach with reliable hemostasis and a cost that can justify their incorporation into routine practice...

..Furthermore, a thorough understanding of the clip design, in particular its unlocking mechanism, is essential and facilitates surgical clip removal...

..This study sought to evaluate the clinical results of a percutaneous approach to mitral valve repair for mitral regurgitation (MR)...

..This Review examines the established selection criteria for surgical repair and discusses the potential impact of new percutaneous approaches...

..These approaches are already attractive for use in older patients and will hopefully make treatments available to many with no current options...

..Despite these limitations, most patients are symptomatically improved for a year or more. BAV remains an effective palliative therapy for selected patients...

..The era of percutaneous valve therapy has clearly arrived, and ongoing trials will define the clinical role for these new therapies...

..While no devices specific for closure of paravalvular leaks have been designed, growing experience with a variety of devices and the use of echo guidance have allowed successful therapy in many complex cases...

..We undertook a prospective multicenter single-arm study to evaluate the feasibility, safety, and efficacy of the MitraClip system (Evalve Inc., Menlo Park, California)...

..We applied this technique to a series of patients and evaluated its feasibility as an alternative to conventional transseptal needle puncture...

..Here, we describe the use of a temporary subcutaneous "Figure-of-Eight" suture technique for venous access site closure after removal of large-caliber sheaths...

..This has simplified postprocedural management in terms of early mobilization and diminished late access site bleeding...

..In the accompanying two articles, we report the results of a survey of the status of SHD training in programs in the United States and define a core curriculum for structural intervention training...

..During hemodynamic assessment prior to antegrade balloon aortic valvuloplasty (BAV), unanticipated transmitral valve pressure gradients (MVG) were noted frequently...

..We describe a fluoroscopically-guided micropuncture technique for accurate placement of large-caliber arterial sheaths...

..Mitral-valve repair can be accomplished with an investigational procedure that involves the percutaneous implantation of a clip that grasps and approximates the edges of the mitral leaflets at the origin of the regurgitant jet...

..The large excursion of the foot of the new closer device may not be as applicable in arteries as small as the brachial artery. Patients who are obese may be best suited for this approach...

..The use of a vascular plug is an effective method for aneurysm occlusion when the anatomy is suitable...

..The purpose of this review is to summarize recent advances in the care of these critically ill patients including the consideration of etiology and pathophysiology as well as the influence of age and adjunctive therapies...

..There is increasing experience in both trials and practice to begin to define the clinical utility of percutanenous leaflet repair, and annuloplasty approaches are undergoing significant development...

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..This allows for the rapid and accurate diagnosis of PAVF when a PFO is not found and for the exclusion of associated PAVF when PFO exists...

..This study reports the initial use of an endovascular technology that enables a double-orifice edge-to-edge mitral valve repair without cardiopulmonary bypass in an animal model...

..Determine if the iCoapsys device could be accurately and safely implanted using a novel transcatheter system...

..We evaluated the ability of a catheter-delivered clip (Evalve, Inc) to achieve edge-to-edge mitral valve approximation without cardiopulmonary bypass and the healing response of this technique...

..Our aim was to assess the accuracy of Real-Time 3D echo (RT3D) to measure the MVA in the immediate post-PMV period. The invasively determined MVA was used as the gold standard...

..The feasibility and accuracy of direct transthoracic 3-dimensional (3D) mitral valve area (MVA) measurements obtained using freehand scanning was investigated in patients with mitral stenosis...

..The effects on the mitral valve gradient (MVG) and mitral valve area (MVA) are not known...

..transesophageal echocardiography (TEE) is used as the primary imaging modality to guide this procedure and is essential to its success...

..0; p <0.0018). In conclusion, quantitative assessment of MR is feasible in a multicenter trial, and percutaneous mitral repair with the MitraClip produces a sustained decrease in MR severity to moderate or less for > or =6 months...

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