Estee Lauder Research Laboratories

Summary

Organization: Estee Lauder Research Laboratories
Country: USA

Top Publications

  1. ncbi Aging of human skin: review of a mechanistic model and first experimental data
    P U Giacomoni
    Clinique Research Laboratories, Melville, NY, USA
    IUBMB Life 49:259-63. 2000
  2. ncbi Prevention of oxidative damage that contributes to the loss of bioenergetic capacity in ageing skin
    H Corstjens
    Estee Lauder Companies, Biological Research Department Europe, Nijverheidsstraat 15, 2260 Oevel, Belgium
    Exp Gerontol 42:924-9. 2007
  3. ncbi Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytes
    Edward Pelle
    Estee Lauder Research Laboratories, Melville, New York 11747, USA
    J Invest Dermatol 128:1280-5. 2008
  4. doi Norepinephrine modulates human dendritic cell activation by altering cytokine release
    Earl Goyarts
    Clinique Laboratories, Melville, NY 11747, USA
    Exp Dermatol 17:188-96. 2008
  5. doi Glycation associated skin autofluorescence and skin elasticity are related to chronological age and body mass index of healthy subjects
    H Corstjens
    Estee Lauder Companies, Biological Research Department Europe, Nijverheidsstraat 15, 2260 Oevel, Belgium
    Exp Gerontol 43:663-7. 2008
  6. doi Osmotic stress induces terminal differentiation in cultured normal human epidermal keratinocytes
    Thomas Mammone
    Estee Lauder Research Laboratories, Melville, NY 11747, USA
    In Vitro Cell Dev Biol Anim 44:135-9. 2008
  7. doi An in vivo study of the mechanical properties of facial skin and influence of aging using digital image speckle correlation
    Isabelle Afriat Staloff
    Estee Lauder Companies, Melville, NY 11747, USA
    Skin Res Technol 14:127-34. 2008
  8. doi Measurement of skin stretch using digital image speckle correlation
    Isabelle Afriat Staloff
    Estee Lauder Companies, Melville, NY 11747, USA
    Skin Res Technol 14:298-303. 2008
  9. doi Gender-linked differences in human skin
    Paolo U Giacomoni
    Clinique Laboratories, Melville, NY 11747, United States
    J Dermatol Sci 55:144-9. 2009
  10. doi Non-sunscreen photoprotection: antioxidants add value to a sunscreen
    Mary S Matsui
    The Clinique Laboratories, New York, NY, USA
    J Investig Dermatol Symp Proc 14:56-9. 2009

Scientific Experts

Detail Information

Publications25

  1. ncbi Aging of human skin: review of a mechanistic model and first experimental data
    P U Giacomoni
    Clinique Research Laboratories, Melville, NY, USA
    IUBMB Life 49:259-63. 2000
    ..Topical application of antioxidants decreases the rate at which skin elasticity and skin thickness are modified...
  2. ncbi Prevention of oxidative damage that contributes to the loss of bioenergetic capacity in ageing skin
    H Corstjens
    Estee Lauder Companies, Biological Research Department Europe, Nijverheidsstraat 15, 2260 Oevel, Belgium
    Exp Gerontol 42:924-9. 2007
    ..Actives specifically selected for optimal protection against these stress situations will decrease skin vulnerability and prevent the premature loss of skin function...
  3. ncbi Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytes
    Edward Pelle
    Estee Lauder Research Laboratories, Melville, New York 11747, USA
    J Invest Dermatol 128:1280-5. 2008
    ....
  4. doi Norepinephrine modulates human dendritic cell activation by altering cytokine release
    Earl Goyarts
    Clinique Laboratories, Melville, NY 11747, USA
    Exp Dermatol 17:188-96. 2008
    ....
  5. doi Glycation associated skin autofluorescence and skin elasticity are related to chronological age and body mass index of healthy subjects
    H Corstjens
    Estee Lauder Companies, Biological Research Department Europe, Nijverheidsstraat 15, 2260 Oevel, Belgium
    Exp Gerontol 43:663-7. 2008
    ..It is hypothesised that skin AGE accumulation contributes to the loss of skin elasticity in aged and/or overweight people...
  6. doi Osmotic stress induces terminal differentiation in cultured normal human epidermal keratinocytes
    Thomas Mammone
    Estee Lauder Research Laboratories, Melville, NY 11747, USA
    In Vitro Cell Dev Biol Anim 44:135-9. 2008
    ..These observations suggest that keratinocytes in the epidermis may use dehydration as a sign to trigger the differentiation of the skin barrier...
  7. doi An in vivo study of the mechanical properties of facial skin and influence of aging using digital image speckle correlation
    Isabelle Afriat Staloff
    Estee Lauder Companies, Melville, NY 11747, USA
    Skin Res Technol 14:127-34. 2008
    ....
  8. doi Measurement of skin stretch using digital image speckle correlation
    Isabelle Afriat Staloff
    Estee Lauder Companies, Melville, NY 11747, USA
    Skin Res Technol 14:298-303. 2008
    ..We introduce the use of digital image speckle correlation (DISC), a non-contact technique, to map, in two dimensions, the surface deformation patterns resulting from skin stretching...
  9. doi Gender-linked differences in human skin
    Paolo U Giacomoni
    Clinique Laboratories, Melville, NY 11747, United States
    J Dermatol Sci 55:144-9. 2009
    ..The physiology of body organs can be affected by gender. Skin and skin appendages are influenced by sex hormones...
  10. doi Non-sunscreen photoprotection: antioxidants add value to a sunscreen
    Mary S Matsui
    The Clinique Laboratories, New York, NY, USA
    J Investig Dermatol Symp Proc 14:56-9. 2009
    ..Journal of Investigative Dermatology Symposium Proceedings (2009) 14, 56-59; doi:10.1038/jidsymp.2009.14...
  11. doi Sunscreens: the impervious path from theory to practice
    Paolo U Giacomoni
    Clinique Laboratories, 125 Pinelawn Road, Melville, NY 11747, USA
    Photochem Photobiol Sci 9:524-9. 2010
    ..This paper describes several aspects of the preparation of commercial sunscreens. It also points out several of the hidden hypotheses which, when not tested, might lead to the overestimation of the protection factor of a product...
  12. ncbi Apoptotic cell death increases with senescence in normal human dermal fibroblast cultures
    Thomas Mammone
    Skin Biology Laboratory, Estee Lauder Companies Inc, 125 Pinelawn Road, Melville, NY 11747, USA
    Cell Biol Int 30:903-9. 2006
    ..The apoptotic markers caspase-3 and cytochrome c were both found to increase in senescent cells. These results suggest the activation of an apoptotic pathway within a population of human fibroblasts as a function of cell passage...
  13. pmc Ageing, science and the cosmetics industry. The micro-inflammatory model serves as a basis for developing effective anti-ageing products for the skin
    Paolo U Giacomoni
    Clinique Laboratories, Melville, NY, USA
    EMBO Rep 6:S45-8. 2005
  14. ncbi Keratinocytes act as a source of reactive oxygen species by transferring hydrogen peroxide to melanocytes
    Edward Pelle
    Estee Lauder Research Laboratories, Melville, New York, USA
    J Invest Dermatol 124:793-7. 2005
    ....
  15. ncbi Successful separation of apoptosis and necrosis pathways in HaCaT keratinocyte cells induced by UVB irradiation
    T Mammone
    Estee Lauder, Melville, New York 11747, USA
    Cell Biol Toxicol 16:293-302. 2000
    ..We conclude that low doses of UVB (5-20 mJ/cm2) induced an apoptotic pathway, whereas increasing doses (greater than 20 mJ/cm2) of UVB produce a direct necrotic effect and inhibit terminal differentiation...
  16. ncbi The cytoprotective effects of exogenous DNA fragments
    Thomas Mammone
    Estee Lauder Research Laboratories, Melville, NY 11747, USA
    Skin Pharmacol Appl Skin Physiol 15:26-34. 2002
    ..This is believed to allow them sufficient time to repair the host DNA. The cellular response to exogenous damaged DNA may be a similar mechanism...
  17. ncbi Cigarette smoke-induced lipid peroxidation in human skin and its inhibition by topically applied antioxidants
    E Pelle
    Estee Lauder Research Laboratories, Melville, NY 11747, USA
    Skin Pharmacol Appl Skin Physiol 15:63-8. 2002
    ..9% in lipid peroxide values was observed. These data demonstrate that peroxidation was induced in human skin by cigarette smoke and subsequently inhibited by the presence of antioxidants...
  18. ncbi Factors of skin ageing share common mechanisms
    P U Giacomoni
    Clinique Laboratories, Melville NY 11747, USA
    Biogerontology 2:219-29. 2001
    ....
  19. ncbi Sulfated polysaccharides from red microalgae have antiinflammatory properties in vitro and in vivo
    Mary S Matsui
    Biological Research Division, The Estee Lauder Companies, 125 Pinelawn Road, Melville, NY 11747, USA
    Appl Biochem Biotechnol 104:13-22. 2003
    ..In addition, the data suggested that the antiinflammatory mechanism for the polysaccharide was, at least in part, due to inhibition of circulating immune cell recruitment toward inflammatory stimuli...
  20. ncbi Impact of stress of marital dissolution on skin barrier recovery: tape stripping and measurement of trans-epidermal water loss (TEWL)
    Neelam Muizzuddin
    Estee Lauder Companies, Melville, NY, USA
    Skin Res Technol 9:34-8. 2003
    ..Skin barrier strength was defined as the number of tape strippings required to disrupt skin barrier, which is a TEWL of 18 g/m2/h or more. Barrier recovery was denoted by the level of TEWL, 3 h and 24 h after barrier disruption...
  21. ncbi Ultraviolet-B-induced oxidative DNA base damage in primary normal human epidermal keratinocytes and inhibition by a hydroxyl radical scavenger
    Edward Pelle
    Estee Lauder Research Laboratories, Melville, New York 11747, USA
    J Invest Dermatol 121:177-83. 2003
    ....
  22. ncbi Bioinformation within the biofield: beyond bioelectromagnetics
    Glen Rein
    Quantum Biology Research Lab, Northport, NY 11768, USA
    J Altern Complement Med 10:59-68. 2004
    ..This model is used to explain a wide variety of anomalies reported in the scientific literature, which can not be explained by traditional biophysics and bioelectromagnetics...
  23. ncbi A mechanistic model for the aging of human skin
    Paolo U Giacomoni
    Clinique Laboratories, Inc and Estee Lauder Research Park, 125 Pinelawn Road, Melville, NY 11747, USA
    Micron 35:179-84. 2004
    ..The micro-inflammatory model of skin aging fails to predict the appearance of age spots on the surface of the skin...
  24. ncbi Normal human keratinocytes pretreated with damaged mRNA are resistant to UVB damage and exhibit increased DNA repair
    T Mammone
    Estee Lauder Research Laboratories, Melville, NY 11747, USA
    Skin Pharmacol Physiol 18:12-9. 2005
    ..Sections of skin models pretreated with UV-damaged mRNA exhibit greater removal of these TT dimers after 24 h. The above evidence suggests that damaged mRNA can trigger a host cell DNA repair pathway...
  25. doi Modification of skin discoloration by a topical treatment containing an extract of Dianella ensifolia: a potent antioxidant
    Thomas Mammone
    Clinique Laboratories, Melville, NY, USA
    J Cosmet Dermatol 9:89-95. 2010
    ..We found that the cosmetic formula containing DP produced an increase in the rate of fading compared to the two pharmaceutical treatments containing HQ...