Christopher L Kliethermes

Summary

Affiliation: Ernest Gallo Clinic and Research Center
Country: USA

Publications

  1. ncbi Genetic independence of mouse measures of some aspects of novelty seeking
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and Portland Alcohol Research Center, Veterans Affairs Medical Center, Portland, OR 97239 3098, USA
    Proc Natl Acad Sci U S A 103:5018-23. 2006
  2. ncbi Anxiety-like behaviors following chronic ethanol exposure
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Neurosci Biobehav Rev 28:837-50. 2005
  3. ncbi Home cage activity and ingestive behaviors in mice following chronic ethanol vapor inhalation
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Physiol Behav 85:479-88. 2005
  4. ncbi Selection for pentobarbital withdrawal severity: correlated differences in withdrawal from other sedative drugs
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and the Portland Alcohol Research Center, Veterans Affairs Medical Center, c o Portland VA Medical Center, Portland, OR 97239, USA
    Brain Res 1009:17-25. 2004
  5. ncbi Validation of a modified mirrored chamber sensitive to anxiolytics and anxiogenics in mice
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Portland Alcohol Research Center, Oregon Health and Science University, VAMC Research R and D 12, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Psychopharmacology (Berl) 169:190-7. 2003
  6. ncbi Pharmacological and genetic influences on hole-board behaviors in mice
    Christopher L Kliethermes
    Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, CA 94608, USA
    Pharmacol Biochem Behav 85:57-65. 2006

Research Grants

  1. Behavioral Prediction of Alcohol and Drug Reinforcement
    CHRISTOPHER KLIETHERMES; Fiscal Year: 2004
  2. Regulation of Ethanol-related Behaviors by Insulin Signaling
    CHRISTOPHER KLIETHERMES; Fiscal Year: 2007

Detail Information

Publications6

  1. ncbi Genetic independence of mouse measures of some aspects of novelty seeking
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and Portland Alcohol Research Center, Veterans Affairs Medical Center, Portland, OR 97239 3098, USA
    Proc Natl Acad Sci U S A 103:5018-23. 2006
    ....
  2. ncbi Anxiety-like behaviors following chronic ethanol exposure
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Neurosci Biobehav Rev 28:837-50. 2005
    ..In addition, standard anxiolytic drugs should ameliorate the anxiogenic-like effects of withdrawal, preferably in multiple tests of anxiety-like behavior...
  3. ncbi Home cage activity and ingestive behaviors in mice following chronic ethanol vapor inhalation
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Physiol Behav 85:479-88. 2005
    ..Further, even in a relatively severe mouse model of alcohol withdrawal, any decreases in general home cage activity are short-lived...
  4. ncbi Selection for pentobarbital withdrawal severity: correlated differences in withdrawal from other sedative drugs
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and the Portland Alcohol Research Center, Veterans Affairs Medical Center, c o Portland VA Medical Center, Portland, OR 97239, USA
    Brain Res 1009:17-25. 2004
    ..These results indicate that some of the same genes that affect the severity of withdrawal from pentobarbital also influence ethanol and zolpidem withdrawal, but that diazepam withdrawal may be less influenced by these genes...
  5. ncbi Validation of a modified mirrored chamber sensitive to anxiolytics and anxiogenics in mice
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Portland Alcohol Research Center, Oregon Health and Science University, VAMC Research R and D 12, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Psychopharmacology (Berl) 169:190-7. 2003
    ..Anxiety is a common disorder in humans that exists in many forms, and animal models of human anxiety are typically employed for the discovery of anxiolytic drugs with human therapeutic potential...
  6. ncbi Pharmacological and genetic influences on hole-board behaviors in mice
    Christopher L Kliethermes
    Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, CA 94608, USA
    Pharmacol Biochem Behav 85:57-65. 2006
    ..However, the results with the genetically heterogeneous mice and HEB and LEB mice suggest that some aspects of the dopaminergic system are involved in head dipping...

Research Grants3

  1. Behavioral Prediction of Alcohol and Drug Reinforcement
    CHRISTOPHER KLIETHERMES; Fiscal Year: 2004
    ..These experiments will provide valuable insights into the genetic association between novelty seeking and drug abuse, and provide a useful model for preclinical evaluation of potential therapeutic agents aimed at reducing dependence. ..
  2. Regulation of Ethanol-related Behaviors by Insulin Signaling
    CHRISTOPHER KLIETHERMES; Fiscal Year: 2007
    ....