Research Topics
| Stacy M PlumSummaryAffiliation: EntreMed Inc Country: USA Publications
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Detail Information
Publications
Administration of a liposomal FGF-2 peptide vaccine leads to abrogation of FGF-2-mediated angiogenesis and tumor developmentS M Plum
EntreMed, Inc, 9640 Medical Center Drive, Rockville, MD 20850, USA
Vaccine 19:1294-303. 2000..These data suggest that a heparin binding domain peptide of FGF-2, when presented to a host in a liposomal adjuvant formulation, can ultimately lead to inhibition of angiogenesis and tumor growth...
Synergistic activity of recombinant human endostatin in combination with adriamycin: analysis of in vitro activity on endothelial cells and in vivo tumor progression in an orthotopic murine mammary carcinoma modelStacy M Plum
EntreMed, Inc, Rockville, Maryland 20850, USA
Clin Cancer Res 9:4619-26. 2003..In this study, we determine the antitumor effect of rhEndostatin administered alone or in combination with Adriamycin against established orthotopic murine mammary carcinoma...
Generation of a specific immunological response to FGF-2 does not affect wound healing or reproductionStacy M Plum
EntreMed, Inc, Rockville, Maryland 20850, USA
Immunopharmacol Immunotoxicol 26:29-41. 2004..Thus, while vaccination against FGF-2 induces a specific FGF-2 antibody response, and inhibits angiogenesis and tumor development in a pathological setting, it does not adversely alter normal physiological events dependent on FGF-2...
Anti-angiogenic vaccines as a treatment modality for cancerStacy M Plum
EntreMed Inc, 9640 Medical Center Drive, Rockville, MD 20850, USA
Curr Opin Investig Drugs 5:1243-6. 2004..In this review we describe a number of novel vaccines that target mediators of angiogenesis and inhibit tumor progression in preclinical models...
Disease modifying and antiangiogenic activity of 2-methoxyestradiol in a murine model of rheumatoid arthritisStacy M Plum
EntreMed, Inc, Rockville, MD 20850, USA
BMC Musculoskelet Disord 10:46. 2009..We investigated the impact of orally administered 2ME2 on the initiation and development of proliferative synovitis using the anti-collagen monoclonal antibodies (CAIA) model...
Identification and characterization of a very low density lipoprotein receptor-binding peptide from tissue factor pathway inhibitor that has antitumor and antiangiogenic activityTodd A Hembrough
EntreMed, Inc, 9640 Medical Center Dr, Rockville, MD 20850, USA
Blood 103:3374-80. 2004....
