Research Topics
| A ShanderSummaryAffiliation: Englewood Hospital and Medical Center Country: USA Publications
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Detail Information
Publications
Clinical consequences of iron overload from chronic red blood cell transfusions, its diagnosis, and its management by chelation therapyAryeh Shander
Department of Anesthesiology, Critical Care Medicine, and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Transfusion 50:1144-55. 2010....- Iron overload and toxicity: implications for anesthesiologistsAryeh Shander
Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
J Clin Anesth 24:419-25. 2012..The management plan should be adjusted to account for iron overload and potential consequences of liver, heart, and other organ involvement... 
Patient blood management in EuropeA Shander
Department of Anaesthesiology, Critical Care Medicine, Pain Management and Hyperbaric Medicine, Englewood Hospital and Medical Center, 350 Engle Street, Englewood, NJ, USA
Br J Anaesth 109:55-68. 2012..After reviewing current PBM practices in Europe, this article offers recommendations supporting its wider implementation, focusing on anaemia management, the first of the three pillars of PBM...- Strategies to reduce the use of blood products: a US perspectiveAryeh Shander
Department of Anesthesiology and Critical Care Medicine, Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Curr Opin Anaesthesiol 25:50-8. 2012..To describe the recent developments in the strategies to reduce allogeneic blood transfusions with emphasis on the impact on clinical outcomes... - Appropriateness of allogeneic red blood cell transfusion: the international consensus conference on transfusion outcomesAryeh Shander
Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, 350 Engle Street, Englewood, NJ 07631, USA
Transfus Med Rev 25:232-246.e53. 2011..In addition, the large number of scenarios in which RBC transfusions were rated as uncertain can serve as a road map to identify areas in need of further investigation... 
Understanding the consequences of transfusion-related acute lung injuryAryeh Shander
Department of Anesthesiology and Critical Care Medicine, New Jersey Institute for the Advancement of Bloodless Medicine and Surgery, Englewood Hospital and Medical Center, 350 Engle Street, Englewood, NJ 07631, USA
Chest 128:598S-604S. 2005..This review summarizes what is known and unknown about the incidence, severity, etiology, diagnosis, and prevention of TRALI and the potential consequences of these knowledge gaps...- Update on transfusion medicineAryeh Shander
Department of Anesthesiology and Critical Care and Hyperbaric Medicine and the New Jersey Institute for the Advancement of Bloodless Medicine and Surgery, Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Pharmacotherapy 27:57S-68S. 2007..The benefits, risks, and several ongoing controversies that relate to the appropriateness and safety of blood product use are also summarized... - Objectives and limitations of bloodless medical careAryeh Shander
Department of Anesthesiology and Critical Care and Hyperbaric Medicine, New Jersey Institute for the Advancement of Bloodless Medicine and Surgery, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Curr Opin Hematol 13:462-70. 2006..To outline the rationale, limitations, and execution of bloodless medical and surgical programs, highlighting characteristics that contribute to successful outcomes... - Estimating the cost of blood: past, present, and future directionsAryeh Shander
Department of Anesthesiology and Critical Care, New Jersey Institute for the Advancement of Bloodless Medicine and Surgery Englewood Hospital and Medical Center, 350 Engle Street, Englewood, NJ 07631, USA
Best Pract Res Clin Anaesthesiol 21:271-89. 2007..g., academic, private, multi- or single-center clinic). These initiatives, their rationale, importance, and future directions are described... - Activity-based costs of blood transfusions in surgical patients at four hospitalsAryeh Shander
The Institute for Patient Blood Management and Bloodless Medicine at Englewood Hospital and Medical Center, Englewood, New Jersey, USA
Transfusion 50:753-65. 2010..Determining the cost of supplying patients with blood transfusions requires an in-depth examination of the complex array of activities surrounding the decision to transfuse... - Why an alternative to blood transfusion?Aryeh Shander
Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Crit Care Clin 25:261-77, Table of Contents. 2009..Global and local shortages are imminent. Alternatives to transfusion provide many advantages, and their use is likely to improve outcomes as safer and more effective agents are developed... - Financial and clinical outcomes associated with surgical bleeding complicationsAryeh Shander
Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Surgery 142:S20-5. 2007..New models for assessing the true costs of transfusion are discussed that allow incorporation and weighing of factors more often obscured in conventional discussions of the cost-effectiveness of transfusion... - Invited commentaryAryeh Shander
Anesthesiology and Critical Care Medicine, Englewood Hospital and Medical Center, 350 Engle St, Englewood, NJ 07631, USA
Ann Thorac Surg 85:844. 2008 - Optimizing transfusion in vascular surgery: is bloodless surgery an option?Aryeh Shander
Department of Anesthesiology and Critical Care Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Vascular 16:S37-47. 2008..Ongoing research offers the possibility of replacement or elimination of allogeneic blood transfusions in a variety of clinical settings... - Timing and incidence of postoperative infections associated with blood transfusion: analysis of 1,489 orthopedic and cardiac surgery patientsAryeh Shander
Department of Anesthesiology, Critical Care Medicine, Pain Management and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Surg Infect (Larchmt) 10:277-83. 2009..Transfusion rates remain high in cardiac and orthopedic surgery and differ widely across physician practices in spite of growing knowledge that allogeneic blood transfusion (ABT) is associated with a risk of postoperative infection... - The unresolved safety concerns of bovine thrombinAryeh Shander
Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, USA
Patient Saf Surg 2:23. 2008..Rather, continued vigilance in the post-surgical setting for bleeding events that may be associated with the development of acquired coagulation factor inhibitors following bovine thrombin administration is warranted... - Clinical outcomes in cardiac surgery: conventional surgery versus bloodless surgeryAryeh Shander
Mount Sinai Hospital, One Gustave L Levy Place, New York, NY 10029, USA
Anesthesiol Clin North America 23:327-45, vii. 2005.... - The safety and efficacy of "bloodless" cardiac surgeryAryeh Shander
Critical Care Medicine, Pain Management and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07361, USA
Semin Cardiothorac Vasc Anesth 9:53-63. 2005.... - Acute normovolemic hemodilutionAryeh Shander
Mount Sinai School of Medicine, Mount Sinai Hospital, New York, New York, USA
Transfusion 44:26S-34S. 2004 - Surgery without bloodAryeh Shander
Department of Anesthesiology, Critical Care Medicine, Pain Management and Hyperbaric Medicine, Englewood Hospital and Medical Center, NJ 07631, USA
Crit Care Med 31:S708-14. 2003..Blood transfusion is a significant adjunct to perioperative resuscitation. However, we aim to elucidate different approaches to minimizing blood loss and avoiding transfusion... - Iron overload and toxicity: the hidden risk of multiple blood transfusionsA Shander
Department of Anesthesiology, Critical Care Medicine, and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Vox Sang 97:185-97. 2009..Cumulative iron overload, in turn, leads to iron toxicity with organ dysfunction and damage... - From bloodless surgery to patient blood managementAryeh Shander
Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Mt Sinai J Med 79:56-65. 2012..Emerging evidence supports that appropriate use of these strategies as part of a multimodal program is a safe and effective way of reducing allogeneic transfusions and improving patient outcomes... - Clinical and economic burden of postoperative pulmonary complications: patient safety summit on definition, risk-reducing interventions, and preventive strategiesAryeh Shander
Englewood Hospital and Medical Center, Englewood, NJ, USA
Crit Care Med 39:2163-72. 2011.... - Use of a hemoglobin-based oxygen carrier in the treatment of severe anemiaAryeh Shander
Department of Anesthesiology and Critical Care Medicine, Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Obstet Gynecol 103:1096-9. 2004..Hemoglobin-based oxygen carriers hold promise for the treatment of acute anemia... - Anemia in the critically illAryeh Shander
Department of Anesthesiology, Critical Care Medicine, Pain Management and Hyperbaric Medicine, Englewood Hospital and Medical Center, NJ 07631, USA
Crit Care Clin 20:159-78. 2004..New approaches, continued research, and an understanding of anemia may result in more consistent and improved outcomes for critically ill patients... - What is really dangerous: anaemia or transfusion?A Shander
Department of Anesthesiology and Critical Care Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Br J Anaesth 107:i41-59. 2011.... - Drug-induced anemia and other red cell disorders: a guide in the age of polypharmacyAryeh Shander
Department of Anesthesiology and Critical Care Medicine, Englewood Hospital and Medical Center, NJ 07631, USA
Curr Clin Pharmacol 6:295-303. 2011.... - Acquired hemophilia: a rare but life-threatening potential cause of bleeding in the intensive care unitAryeh Shander
Department of Anesthesiology and Critical Care Medicine, Englewood Hospital and Medical Center, 350 Engle Street, Englewood, NJ 07631, USA
Intensive Care Med 37:1240-9. 2011..The purpose of this review is to familiarize the intensive care specialist with this underrecognized cause of bleeding, with an emphasis on diagnosis and treatment... - A practical approach to achieving bloodless surgeryS Ozawa
New Jersey Institute for the Advancement of Bloodless Medicine and Surgery, Englewood Hospital and Medical Center, Englewood, NJ, USA
AORN J 74:34-40, 42-7; quiz 48, 50-4. 2001..This article reviews the scientific and clinical literature regarding bloodless surgery and describes the application of a full-service, bloodless program within a community hospital... - Prevalence and outcomes of anemia in surgery: a systematic review of the literatureAryeh Shander
Department of Anesthesiology, Englewood Hospital Medical Center, Englewood, New Jersey 07631, USA
Am J Med 116:58S-69S. 2004..Establishing a uniform definition and specifically evaluating the effect of anemia on outcomes are important considerations for future study... - When blood is not an option: factors affecting survival after the use of a hemoglobin-based oxygen carrier in 54 patients with life-threatening anemiaColin F Mackenzie
Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland, USA
Anesth Analg 110:685-93. 2010..In consenting Jehovah's Witness patients and others for whom blood is contraindicated or not available, hemoglobin-based oxygen carrier (HBOC)-201 may enable survival in acutely anemic patients while underlying conditions are treated... - Postoperative blood loss and transfusion associated with use of Hextend in cardiac surgery patients at a blood conservation centerDavid M Moskowitz
Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Transfusion 48:768-75. 2008..doses of 1 to 20 mL/kg and allogeneic transfusion and 24-hour chest tube drainage (CTD) in cardiac surgeries at a blood conservation center... - Multidisciplinary management of a Jehovah's Witness patient for the removal of a renal cell carcinoma extending into the right atriumDavid M Moskowitz
Department of Anesthesiology, Division of Cardiothoracic Anesthesia, Critical Care Medicine, Pain Management and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Can J Anaesth 49:402-8. 2002..To highlight the management of a Jehovah's witness surgical patient presenting for cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest... - Predictors of transfusion requirements for cardiac surgical procedures at a blood conservation centerDavid M Moskowitz
Department of Anesthesiology and Critical Care Medicine, Englewood Hospital and Medical Center, Englewood, New Jersey, USA
Ann Thorac Surg 77:626-34. 2004.... - Use of the Hemobag for modified ultrafiltration in a Jehovah's Witness patient undergoing cardiac surgeryDavid M Moskowitz
Department of Anesthesiology, Critical Care Medicine, Pain Management and Hyperbaric Medicine, Englewood Hospital and Medical Center, 305 Engle Street, Englewood, New Jersey 07631, USA
J Extra Corpor Technol 38:265-70. 2006..This case report describes how to set up and operate the Hemobag in a Jehovah's Witness patient undergoing cardiac surgery that requires an extracorporeal circuit... - The impact of blood conservation on outcomes in cardiac surgery: is it safe and effective?David M Moskowitz
Department of Anesthesiology, Critical Care Medicine, Hyperbaric Medicine and Pain Management, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
Ann Thorac Surg 90:451-8. 2010..This study examines whether blood conservation is equally safe or superior to the common practice of transfusion in cardiac surgery... - Multidisciplinary approach to the challenge of hemostasisJerrold H Levy
Department of Anesthesiology, Division of Cardiothoracic Anesthesiology and Critical Care, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Anesth Analg 110:354-64. 2010..Because of the complexities of maintaining hemostatic balance, advances in hemostasis research and continuing communication across specialties are required to improve patient care and outcomes... - Emerging risks and outcomes of blood transfusion in surgeryAryeh Shander
Department of Anesthesiology, Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ, USA
Semin Hematol 41:117-24. 2004..In the meantime, blood product conservation techniques should become part of routine transfusion medicine... - Can intravenous iron therapy meet the unmet needs created by the new restrictions on erythropoietic stimulating agents?Aryeh Shander
Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ, USA
Transfusion 50:719-32. 2010..We will also review the available IV iron agents and their comparative safety profiles... - Current concepts in reoperative cardiac surgeryJoanna Chilwe
Department of Cardiothoracic Surgery, Mount Sinai Medical Center, New York, NY 10029, USA
Semin Cardiothorac Vasc Anesth 13:206-14. 2009..This article summarizes techniques used in reoperative cardiac surgery, outlines a risk-stratified approach to operative planning, and reviews the literature on outcomes after reoperative valvular and coronary surgery... - Blood conservation in practice: an overviewAryeh Shander
Department of Anesthesiology, Englewood Hospital and Medical Center, Englewood, New Jersey 07631, USA
Br J Hosp Med (Lond) 70:16-21. 2009..Blood conservation provides an alternative, with potential to improve patient care with limited or no blood transfusion. Many approaches are available, but the most essential ones are simple and cost free... - Blood conservation strategies in Jehovah's Witness patients undergoing complex aortic surgery: a report of three casesPaul G Loubser
Department of Anesthesiology, McAllen Medical Center, McAllen, TX, USA
J Cardiothorac Vasc Anesth 17:528-35. 2003 - Blood salvage use in gynecologic oncologyNimesh P Nagarsheth
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai Medical Center, New York, New York 10029 6574, USA
Transfusion 49:2048-53. 2009..Recent studies have demonstrated that filtering the salvaged blood using a leukoreduction filter (LRF) significantly decreases the number of cancer cells in the recovered RBC aliquot in a variety of cancer types... - Bloodless surgery in a Jehovah's Witness patient with a 12.7-kg uterine leiomyosarcomaNimesh P Nagarsheth
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Science, Englewood Hospital and Medical Center, Englewood, New Jersey, USA
J Surg Educ 64:212-9. 2007..The techniques of bloodless surgery have been incorporated in order to care for a patient with a large uterine sarcoma with involvement and invasion into adjacent organs... - Blood and starch in cardiac surgeryAryeh Shander
Chest 125:2369-70. 2004 - Evolution in alternatives to blood transfusionLawrence T Goodnough
Washington University School of Medicine, St Louis, MO 63110, USA
Hematol J 4:87-91. 2003 - The long and winding road of acute normovolemic hemodilutionAryeh Shander
Transfusion 46:1075-9. 2006 - Blood managementLawrence T Goodnough
Department of Pathology and Medicine, Stanford University Medical Center, 300 Pasteur Dr, M C 5626, Stanford, CA 94305, USA
Arch Pathol Lab Med 131:695-701. 2007..We provide an overview of the principles of blood management: the appropriate use of blood and blood components, with a goal of minimizing their use... - Blood use in elective surgery: the Austrian benchmark studyHans Gombotz
Department of Anesthesiology and Intensive Care, General Hospital Linz, Krankenhausstrasse 9, A 4020 Linz, Austria
Transfusion 47:1468-80. 2007..The goal of this study was to measure and to compare the current transfusion practice and to identify predictors of transfusion in public hospitals to develop strategies to optimize transfusion practices... - Bloodless medicine: clinical care without allogeneic blood transfusionLawrence T Goodnough
Washington University School of Medicine, St. Louis, Missouri, USA
Transfusion 43:668-76. 2003 - Transfusion medicine: looking to the futureLawrence T Goodnough
Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
Lancet 361:161-9. 2003..Finally, serious difficulties in blood safety and availability for poor, developing countries require innovative strategies and commitment of resources... - Does acute normovolemic hemodilution work in cardiac surgery?David M Moskowitz
Anesthesiology 97:1322; author reply 1322-3. 2002 - Invited commentaryLawrence Tim Goodnough
Department of Pathology and Medicine, Stanford Medical Center, 300 Pasteur Dr H-1402, Stanford, CA 94304-5626, USA
Ann Thorac Surg 78:1554-5. 2004 - Anemia screening in elective surgery: definition, significance and patients' interestsAryeh Shander
Anesth Analg 103:778-9; author reply 779-80. 2006 - Detection, evaluation, and management of anemia in the elective surgical patientLawrence T Goodnough
Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive H 1402, Stanford, CA 94305 5626, USA
Anesth Analg 101:1858-61. 2005.... - Hydroxyethyl starch and risk of bleeding: the missing linksAryeh Shander
Anesth Analg 102:968; author reply 968. 2006 - Another headache for anemiaAryeh Shander
Crit Care Med 35:2454-6. 2007 - Case 3-2008. The use of acute normovolemic hemodilution during cardiac surgery in a patient with human immunodeficiency virus infectionPaul G Loubser
National Cardiac Anesthesia Consultants, Sugar Land, TX 77478, USA
J Cardiothorac Vasc Anesth 22:474-81. 2008 - Hemoglobin-based blood substitutes and risk of myocardial infarction and deathAryeh Shander
JAMA 300:1296-7; author reply 1298-9. 2008 - The theory and practice of bloodless surgeryVladimir Martyn
Centre for Blood Conservation, Fremantle Kaleeya Hospital, Australia
Transfus Apher Sci 27:29-43. 2002..Accordingly, a brief overview of the history, theory and practice of bloodless surgery is presented, along with the clinical and institutional management requirements...