Dorothea Zahner

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc Induction of efflux-mediated macrolide resistance in Streptococcus pneumoniae
    Scott T Chancey
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Antimicrob Agents Chemother 55:3413-22. 2011
  2. pmc Increase in pilus islet 2-encoded pili among Streptococcus pneumoniae isolates, Atlanta, Georgia, USA
    Dorothea Zahner
    Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Emerg Infect Dis 16:955-62. 2010
  3. pmc Mitis group streptococci express variable pilus islet 2 pili
    Dorothea Zahner
    Division of Infectious Diseases, Department of Medicine, Atlanta, Georgia, United States of America
    PLoS ONE 6:e25124. 2011
  4. pmc Pilus backbone protein PitB of Streptococcus pneumoniae contains stabilizing intramolecular isopeptide bonds
    Dorothea Zahner
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, 1639 Pierce Dr, Suite 2101, Atlanta, GA 30322, USA
    Biochem Biophys Res Commun 409:526-31. 2011
  5. pmc SipA is required for pilus formation in Streptococcus pyogenes serotype M3
    Dorothea Zahner
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Bacteriol 190:527-35. 2008
  6. pmc Human antimicrobial peptide LL-37 induces MefE/Mel-mediated macrolide resistance in Streptococcus pneumoniae
    Dorothea Zahner
    Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Antimicrob Agents Chemother 54:3516-9. 2010
  7. doi request reprint Linkage of T3 and Cpa pilins in the Streptococcus pyogenes M3 pilus
    Bernard R Quigley
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Microbiol 72:1379-94. 2009
  8. pmc Acquired inducible antimicrobial resistance in Gram-positive bacteria
    Scott T Chancey
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Future Microbiol 7:959-78. 2012
  9. ncbi request reprint Pili with strong attachments: Gram-positive bacteria do it differently
    June R Scott
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Microbiol 62:320-30. 2006
  10. pmc The LuxS-dependent quorum-sensing system regulates early biofilm formation by Streptococcus pneumoniae strain D39
    Jorge E Vidal
    Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Infect Immun 79:4050-60. 2011

Collaborators

Detail Information

Publications10

  1. pmc Induction of efflux-mediated macrolide resistance in Streptococcus pneumoniae
    Scott T Chancey
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Antimicrob Agents Chemother 55:3413-22. 2011
    ..The induction of mef(E)-mel expression by inducing macrolides appears to be based on specific interactions of the macrolide C-5 saccharide with the ribosome that alleviate transcriptional attenuation of mef(E)-mel...
  2. pmc Increase in pilus islet 2-encoded pili among Streptococcus pneumoniae isolates, Atlanta, Georgia, USA
    Dorothea Zahner
    Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Emerg Infect Dis 16:955-62. 2010
    ..The increase in PI-2-containing isolates and the finding that isolates of all identified serotypes expressed highly conserved PI-2 pili supports their potential as a vaccine candidate...
  3. pmc Mitis group streptococci express variable pilus islet 2 pili
    Dorothea Zahner
    Division of Infectious Diseases, Department of Medicine, Atlanta, Georgia, United States of America
    PLoS ONE 6:e25124. 2011
    ..Their close relative, the human pathogen S. pneumoniae uses pilus-islet 2 (PI-2)-encoded pili to facilitate adhesion to eukaryotic cells...
  4. pmc Pilus backbone protein PitB of Streptococcus pneumoniae contains stabilizing intramolecular isopeptide bonds
    Dorothea Zahner
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, 1639 Pierce Dr, Suite 2101, Atlanta, GA 30322, USA
    Biochem Biophys Res Commun 409:526-31. 2011
    ..However, absence of these bonds substantially decreased the melting temperature of the PitB-derivatives, indicating a stabilizing function of these bonds in PitB of the pneumococcal type 2 pilus...
  5. pmc SipA is required for pilus formation in Streptococcus pyogenes serotype M3
    Dorothea Zahner
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Bacteriol 190:527-35. 2008
    ..A possible chaperone-like function of SipA2 in T3 pilus formation is discussed...
  6. pmc Human antimicrobial peptide LL-37 induces MefE/Mel-mediated macrolide resistance in Streptococcus pneumoniae
    Dorothea Zahner
    Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Antimicrob Agents Chemother 54:3516-9. 2010
    ..Such induction may impact the efficacy of host defenses and of macrolide-based treatment of pneumococcal disease...
  7. doi request reprint Linkage of T3 and Cpa pilins in the Streptococcus pyogenes M3 pilus
    Bernard R Quigley
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Microbiol 72:1379-94. 2009
    ....
  8. pmc Acquired inducible antimicrobial resistance in Gram-positive bacteria
    Scott T Chancey
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Future Microbiol 7:959-78. 2012
    ..g., oxacillin), glycopeptides (e.g., vancomycin) and the polypeptide bacitracin, leading to drug inactivation or resistance due to cell wall alterations...
  9. ncbi request reprint Pili with strong attachments: Gram-positive bacteria do it differently
    June R Scott
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Microbiol 62:320-30. 2006
    ..This enzyme is encoded elsewhere on the genome. Because pili of Gram-positive bacteria have not been extensively investigated yet, we hope that this MicroReview will help to pinpoint the areas most in need of further study...
  10. pmc The LuxS-dependent quorum-sensing system regulates early biofilm formation by Streptococcus pneumoniae strain D39
    Jorge E Vidal
    Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Infect Immun 79:4050-60. 2011
    ..In conclusion, the luxS-controlled QS system is a key regulator of early biofilm formation by S. pneumoniae strain D39...