David S Yu

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc One stone, two birds: CDK9-directed activation of UBE2A regulates monoubiquitination of both H2B and PCNA
    Hui Zhang
    Department of Radiation Oncology Emory University School of Medicine Atlanta, GA USA
    Cell Cycle 11:2418. 2012
  2. pmc A role for CDK9-cyclin K in maintaining genome integrity
    David S Yu
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA
    Cell Cycle 10:28-32. 2011
  3. pmc ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA
    Hui Zhang
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cell Rep 14:1435-47. 2016
  4. pmc A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response
    Scott C Smith
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Nucleic Acids Res 42:11517-27. 2014
  5. pmc Pronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma
    Lauren E Colbert
    Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia
    Cancer 119:3148-55. 2013
  6. pmc Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
    David S Yu
    Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    EMBO Rep 11:876-82. 2010
  7. pmc SIRT2 directs the replication stress response through CDK9 deacetylation
    Hui Zhang
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 110:13546-51. 2013

Collaborators

  • Jie Wang
  • Walter J Curran
  • William A Hall
  • N Volkan Adsay
  • Charles A Staley
  • David A Kooby
  • Shishir K Maithel
  • Hui Zhang
  • Matthew D Warren
  • Claire W Hardy
  • Matthew Z Madden
  • Ya Wang
  • Elaine A Liu
  • Mylin A Torres
  • Yunfeng Pan
  • David Gius
  • Seong Hoon Park
  • Nicholas T Seyfried
  • Duc M Duong
  • Scott C Smith
  • Aleksandra V Petrova
  • Brooke G Pantazides
  • Lauren E Colbert
  • Chunyang Li
  • Bing Yu
  • Vishal R Dhere
  • Ivan Pradilla
  • William S Dynan
  • Xingming Deng
  • PamelaSara E Head
  • Paul W Doetsch
  • Maohua Xie
  • Waaqo Daddacha
  • Xingzhe Li
  • Dong Liang
  • Hongyan Wang
  • Soumon Rudra
  • Shahrzad Ehdaivand
  • M Hope Robinson
  • Khanjan Gandhi
  • Joseph W Shelton
  • Hyun Seok Kim
  • Athanassios Vassilopoulos
  • Oleksandra Karpiuk
  • Steven A Johnsen
  • So Jeong Park
  • Bassel F El-Rayes
  • Sarah B Fisher
  • Burcu Saka
  • Jerome C Landry
  • Jeanne Kowalski

Detail Information

Publications7

  1. pmc One stone, two birds: CDK9-directed activation of UBE2A regulates monoubiquitination of both H2B and PCNA
    Hui Zhang
    Department of Radiation Oncology Emory University School of Medicine Atlanta, GA USA
    Cell Cycle 11:2418. 2012
    ..Comment on: Shchebet A, et al. Cell Cycle 2012; 11:2122-7...
  2. pmc A role for CDK9-cyclin K in maintaining genome integrity
    David S Yu
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA
    Cell Cycle 10:28-32. 2011
    ..The direct role of CDK9-cyclin K in pathways that maintain genome integrity in response to replication stress appear to be evolutionarily conserved...
  3. pmc ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA
    Hui Zhang
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cell Rep 14:1435-47. 2016
    ....
  4. pmc A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response
    Scott C Smith
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Nucleic Acids Res 42:11517-27. 2014
    ..Thus, NEK9 is a critical component of the RSR that promotes CHK1 activity, maintaining genome integrity following challenges to DNA replication. ..
  5. pmc Pronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma
    Lauren E Colbert
    Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia
    Cancer 119:3148-55. 2013
    ..The goal of the current study was to evaluate the prognostic value of MLKL expression in patients with pancreatic adenocarcinoma (PAC)...
  6. pmc Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
    David S Yu
    Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    EMBO Rep 11:876-82. 2010
    ..These results reveal an unexpectedly direct role for CDK9-cyclin K in checkpoint pathways that maintain genome integrity in response to replication stress...
  7. pmc SIRT2 directs the replication stress response through CDK9 deacetylation
    Hui Zhang
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 110:13546-51. 2013
    ....