Research Topics
| Guang Jer WuSummaryAffiliation: Emory University Country: USA Publications
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Detail Information
Publications
Expression of a human cell adhesion molecule, MUC18, in prostate cancer cell lines and tissuesG J Wu
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Prostate 48:305-15. 2001....
Isolation and characterization of the major form of human MUC18 cDNA gene and correlation of MUC18 over-expression in prostate cancer cell lines and tissues with malignant progressionG J Wu
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
Gene 279:17-31. 2001..Furthermore, the lacking of predominant cytoplasmic membrane expression of MUC18 appeared to correlate with malignant progression of prostate cancer...
Ectopical expression of human MUC18 increases metastasis of human prostate cancer cellsGuang Jer Wu
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
Gene 327:201-13. 2004..We therefore conclude that HuMUC18 is an important determinant in increasing metastasis of human prostate cancer LNCaP cells to distant organs in a nude mouse model...
Increased expression of MUC18 correlates with the metastatic progression of mouse prostate adenocarcinoma in the TRAMP modelGuang Jer Wu
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Urol 173:1778-83. 2005..In this study we investigated the possible correlation of increased MUC18 expression with the malignant progression of prostate cancer in the TRAMP model...
Enforced expression of MCAM/MUC18 increases in vitro motility and invasiveness and in vivo metastasis of two mouse melanoma K1735 sublines in a syngeneic mouse modelGuang Jer Wu
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
Mol Cancer Res 6:1666-77. 2008....
Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cellsGuo Fang Zeng
Bioengineering College, Chongqing University, Chongqing 400044, China
BMC Cancer 11:113. 2011..To resolve this, we have re-investigated the role of this CAM in the progression of human breast cancer cells...
Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse modelChia Ling Hsieh
Molecular Urology and Therapeutic Program, Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Prostate 67:685-91. 2007....
Enforced expression of METCAM/MUC18 increases tumorigenesis of human prostate cancer LNCaP cells in nude miceGuang Jer Wu
Department of Microbiology and Immunology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA
J Urol 185:1504-12. 2011..To investigate this and determine whether human metastasis cell adhesion molecule/MUC18 may act as a possible tumor progression gene, we studied the effect of its enforced expression on LNCaP cell tumorigenesis...
