D W Wright

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi A novel technology to screen for cognitive impairment in the elderly
    David W Wright
    Emory University School of Medicine, Department of Emergency Medicine, Atlanta, GA 30303, USA
    Am J Alzheimers Dis Other Demen 26:484-91. 2011
  2. ncbi Use of a novel technology for presenting screening measures to detect mild cognitive impairment in elderly patients
    D W Wright
    Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Int J Clin Pract 64:1190-7. 2010
  3. ncbi ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury
    David W Wright
    Department of Emergency Medicine, School of Medicine of Emory University, Atlanta, GA, USA
    Ann Emerg Med 49:391-402, 402.e1-2. 2007
  4. ncbi Enrolling subjects by exception from consent versus proxy consent in trauma care research
    David W Wright
    Department of Emergency Medicine, School of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Ann Emerg Med 51:355-60, 360.e1-3. 2008
  5. ncbi Progesterone in the clinical treatment of acute traumatic brain injury
    Donald G Stein
    Department of Emergency Medicine, Brain Research Laboratory, Emory University, Atlanta, GA 30322, USA
    Expert Opin Investig Drugs 19:847-57. 2010
  6. ncbi Shedding new light on the "safe" club drug: methylenedioxymethamphetamine (ecstasy)-related fatalities
    Manish M Patel
    Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA 30333, USA
    Acad Emerg Med 11:208-10. 2004
  7. ncbi Proxy identification: a time-dependent analysis
    David W Wright
    Department of Emergency Medicine, Emory University, Atlanta, GA 30303, USA
    Acad Emerg Med 11:204-7. 2004
  8. ncbi The DETECT system: portable, reduced-length neuropsychological testing for mild traumatic brain injury via a novel immersive environment
    J M Barker
    College of Computing, Georgia Institute of Technology, 801 Atlanta Drive, Atlanta, GA 30332 0280, USA
    J Med Eng Technol 31:161-9. 2007
  9. ncbi Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats
    D W Wright
    Department of Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Neurotrauma 18:901-9. 2001
  10. ncbi Steady-state serum concentrations of progesterone following continuous intravenous infusion in patients with acute moderate to severe traumatic brain injury
    David W Wright
    Department of Emergency Medicine, Emory University School of Medicine, Emergency Medicine Research Center, 49 Jessie Hill Jr Drive, Atlanta, GA 30303, USA
    J Clin Pharmacol 45:640-8. 2005

Research Grants

  1. Neurorehabilitation with Progesterone & Pregnenolone
    David Wright; Fiscal Year: 2005
  2. ProTECT II: Progesterone for TBI, MCCT Planning Grant
    David Wright; Fiscal Year: 2007
  3. Neurological Emergencies Treatment Trials (NETT)
    David Wright; Fiscal Year: 2007

Detail Information

Publications50

  1. ncbi A novel technology to screen for cognitive impairment in the elderly
    David W Wright
    Emory University School of Medicine, Department of Emergency Medicine, Atlanta, GA 30303, USA
    Am J Alzheimers Dis Other Demen 26:484-91. 2011
    ..DETECT is a portable device developed to rapidly perform cognitive testing in diverse settings. This study compares DETECT with formal clinical assessment...
  2. ncbi Use of a novel technology for presenting screening measures to detect mild cognitive impairment in elderly patients
    D W Wright
    Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Int J Clin Pract 64:1190-7. 2010
    ..Display Enhanced TEsting for Cognitive impairment and Traumatic brain injury (DETECT) addresses these issues by creating an immersive environment for the brief administration of neuropsychological (NP) measures...
  3. ncbi ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury
    David W Wright
    Department of Emergency Medicine, School of Medicine of Emory University, Atlanta, GA, USA
    Ann Emerg Med 49:391-402, 402.e1-2. 2007
    ..Laboratory evidence indicates that progesterone has potent neuroprotective effects. We conducted a pilot clinical trial to assess the safety and potential benefit of administering progesterone to patients with acute traumatic brain injury...
  4. ncbi Enrolling subjects by exception from consent versus proxy consent in trauma care research
    David W Wright
    Department of Emergency Medicine, School of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Ann Emerg Med 51:355-60, 360.e1-3. 2008
    ..The objective of this study is to compare the time required to enroll brain-injured trauma patients in a study with proxy consent versus exception from consent...
  5. ncbi Progesterone in the clinical treatment of acute traumatic brain injury
    Donald G Stein
    Department of Emergency Medicine, Brain Research Laboratory, Emory University, Atlanta, GA 30322, USA
    Expert Opin Investig Drugs 19:847-57. 2010
    ..Traumatic brain injury (TBI) has yet to find a safe and effective acute-stage neuroprotective treatment. Experimental drugs targeting a single receptor mechanism, gene, or brain locus have failed...
  6. ncbi Shedding new light on the "safe" club drug: methylenedioxymethamphetamine (ecstasy)-related fatalities
    Manish M Patel
    Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA 30333, USA
    Acad Emerg Med 11:208-10. 2004
    ..To report the pathology, toxicology, cause, and manner of death in 3,4-methylenedioxymethamphetamine (MDMA)-associated fatalities in the United States. Although use trends are increasing, data regarding the hazards of MDMA are limited...
  7. ncbi Proxy identification: a time-dependent analysis
    David W Wright
    Department of Emergency Medicine, Emory University, Atlanta, GA 30303, USA
    Acad Emerg Med 11:204-7. 2004
    ..To describe the availability of next-of-kin (NOK) for proxy consent over the 24-hour time period following presentation of major trauma patients to a Level I trauma center...
  8. ncbi The DETECT system: portable, reduced-length neuropsychological testing for mild traumatic brain injury via a novel immersive environment
    J M Barker
    College of Computing, Georgia Institute of Technology, 801 Atlanta Drive, Atlanta, GA 30332 0280, USA
    J Med Eng Technol 31:161-9. 2007
    ..The immersive environment, portability, and brevity of the DETECT system allow for real-time cognitive testing in situations previously deemed impractical or unavailable for mTBI patients...
  9. ncbi Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats
    D W Wright
    Department of Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Neurotrauma 18:901-9. 2001
    ..These findings confirm that progesterone significantly decreases cerebral edema after TBI in adult male subjects...
  10. ncbi Steady-state serum concentrations of progesterone following continuous intravenous infusion in patients with acute moderate to severe traumatic brain injury
    David W Wright
    Department of Emergency Medicine, Emory University School of Medicine, Emergency Medicine Research Center, 49 Jessie Hill Jr Drive, Atlanta, GA 30303, USA
    J Clin Pharmacol 45:640-8. 2005
    ..In addition, t(1/2) was longer and V(d) was higher than anticipated. These results demonstrate that stable PG concentrations can be rapidly achieved following TBI...
  11. ncbi Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury
    Edward H Pettus
    Department of Cell Biology, Emory University, Atlanta, GA 30322, USA
    Brain Res 1049:112-9. 2005
    ..The therapeutic benefit of post-TBI progesterone administration may be due to its salutary effect on inflammatory proteins known to increase immune cell invasion and cerebral edema...
  12. ncbi Does progesterone have neuroprotective properties?
    Donald G Stein
    Brain Research Laboratory, Department of Emergency Medicine, School of Medicine, Emory University, Atlanta, GA 30322, USA
    Ann Emerg Med 51:164-72. 2008
    ..All are plausible mechanisms of neuroprotection...
  13. ncbi Gender and traumatic brain injury: do the sexes fare differently?
    Jonathan J Ratcliff
    Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA
    Brain Inj 21:1023-30. 2007
    ..To examine the relationship between gender and cognitive recovery 1 year following traumatic brain injury (TBI)...
  14. ncbi Effects of medroxyprogesterone acetate on cerebral oedema and spatial learning performance after traumatic brain injury in rats
    David W Wright
    Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Brain Inj 22:107-13. 2008
    ....
  15. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 8. Cerebral perfusion pressure
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S31-3. 2003
  16. ncbi Guidelines for the management of severe traumatic brain injury. X. Brain oxygen monitoring and thresholds
    Susan L Bratton
    J Neurotrauma 24:S65-70. 2007
  17. ncbi Guidelines for the management of severe traumatic brain injury. IX. Cerebral perfusion thresholds
    Susan L Bratton
    J Neurotrauma 24:S59-64. 2007
  18. ncbi Guidelines for the management of severe traumatic brain injury. XI. Anesthetics, analgesics, and sedatives
    Susan L Bratton
    J Neurotrauma 24:S71-6. 2007
  19. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 2: Trauma systems, pediatric trauma centers, and the neurosurgeon
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S5-8. 2003
  20. ncbi Guidelines for the management of severe traumatic brain injury. VIII. Intracranial pressure thresholds
    Susan L Bratton
    J Neurotrauma 24:S55-8. 2007
  21. ncbi Guidelines for the management of severe traumatic brain injury. I. Blood pressure and oxygenation
    Susan L Bratton
    J Neurotrauma 24:S7-13. 2007
  22. ncbi Guidelines for the management of severe traumatic brain injury. XIII. Antiseizure prophylaxis
    Susan L Bratton
    J Neurotrauma 24:S83-6. 2007
  23. ncbi Guidelines for the management of severe traumatic brain injury. XII. Nutrition
    Susan L Bratton
    J Neurotrauma 24:S77-82. 2007
  24. ncbi Guidelines for the management of severe traumatic brain injury. XIV. Hyperventilation
    Susan L Bratton
    J Neurotrauma 24:S87-90. 2007
  25. ncbi Guidelines for the management of severe traumatic brain injury. XV. Steroids
    Susan L Bratton
    J Neurotrauma 24:S91-5. 2007
  26. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 7. Intracranial pressure monitoring technology
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S28-30. 2003
  27. ncbi Guidelines for prehospital management of traumatic brain injury 2nd edition
    Neeraj Badjatia
    Columbia University Medical Center, Neurological Institute, USA
    Prehosp Emerg Care 12:S1-52. 2008
  28. ncbi Depression and poverty among rural women: a relationship of social causation or social selection?
    Leigh A Simmons
    Department of Family Studies, University of Kentucky, Lexington, Kentucky 40506 0054, USA
    J Rural Health 24:292-8. 2008
    ..The purpose of this study was to test the competing theories of social causation and social selection to assess the relationship between depression and economic status for a sample of rural, low-income women in the United States...
  29. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 1: Introduction
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S2-4. 2003
  30. ncbi Guidelines for the management of severe traumatic brain injury. VII. Intracranial pressure monitoring technology
    Susan L Bratton
    J Neurotrauma 24:S45-54. 2007
  31. ncbi Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring
    Susan L Bratton
    J Neurotrauma 24:S37-44. 2007
  32. ncbi Guidelines for the management of severe traumatic brain injury. V. Deep vein thrombosis prophylaxis
    Susan L Bratton
    J Neurotrauma 24:S32-6. 2007
  33. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 10. The role of cerebrospinal fluid drainage in the treatment of severe pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S38-9. 2003
  34. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 11. Use of hyperosmolar therapy in the management of severe pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S40-4. 2003
  35. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 12. Use of hyperventilation in the acute management of severe pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S45-8. 2003
  36. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 13. The use of barbiturates in the control of intracranial hypertension in severe pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S49-52. 2003
  37. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 14. The role of temperature control following severe pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S53-5. 2003
  38. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 15. Surgical treatment of pediatric intracranial hypertension
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S56-9. 2003
  39. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 16. The use of corticosteroids in the treatment of severe pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S60-4. 2003
  40. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 17. Critical pathway for the treatment of established intracranial hypertension in pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S65-7. 2003
  41. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 18. Nutritional support
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S68-71. 2003
  42. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 19. The role of anti-seizure prophylaxis following severe pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S72-5. 2003
  43. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 6. Threshold for treatment of intracranial hypertension
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S25-7. 2003
  44. ncbi The role of sexual satisfaction, age, and cardiac risk factors in the reduction of post-MI anxiety
    Elaine E Steinke
    School of Nursing, Wichita State University, 1845 Fairmount, Wichita, Kansas, 67260 0041, USA
    Eur J Cardiovasc Nurs 5:190-6. 2006
    ..Anxiety is common after myocardial infarction (MI); however, little is known about the role of sexual satisfaction and return to sexual activity on anxiety post-MI...
  45. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 5. Indications for intracranial pressure monitoring in pediatric patients with severe traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S19-24. 2003
  46. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 3. Prehospital airway management
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S9-11. 2003
  47. ncbi Guidelines for the management of severe traumatic brain injury. II. Hyperosmolar therapy
    Susan L Bratton
    J Neurotrauma 24:S14-20. 2007
  48. ncbi Guidelines for the management of severe traumatic brain injury. III. Prophylactic hypothermia
    Susan L Bratton
    J Neurotrauma 24:S21-5. 2007
  49. ncbi Guidelines for the management of severe traumatic brain injury. IV. Infection prophylaxis
    Susan L Bratton
    J Neurotrauma 24:S26-31. 2007
  50. ncbi Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 9. Use of sedation and neuromuscular blockade in the treatment of severe pediatric traumatic brain injury
    P David Adelson
    University of Pittsburgh/Children's Hospital, USA
    Pediatr Crit Care Med 4:S34-7. 2003

Research Grants4

  1. Neurorehabilitation with Progesterone & Pregnenolone
    David Wright; Fiscal Year: 2005
    ..Therefore, we will examine two delayed treatment paradigms (7 days & 28 days post injury) on the recovery process at the behavioral and morphological levels of analysis. ..
  2. ProTECT II: Progesterone for TBI, MCCT Planning Grant
    David Wright; Fiscal Year: 2007
    ....
  3. Neurological Emergencies Treatment Trials (NETT)
    David Wright; Fiscal Year: 2007
    ....