P W F Wilson

Summary

Affiliation: Emory University
Country: USA

Publications

  1. doi request reprint An international model to predict recurrent cardiovascular disease
    Peter W F Wilson
    Atlanta VA Medical Center and Cardiology Division, Emory University School of Medicine, GA, USA
    Am J Med 125:695-703.e1. 2012
  2. doi request reprint Prediction of cardiovascular disease events
    Peter W F Wilson
    Atlanta VAMC Epidemiology and Genetics Section, Emory Clinical Cardiovascular Research Institute, Atlanta, GA 30322, USA
    Cardiol Clin 29:1-13. 2011
  3. doi request reprint Cardiometabolic risk: a Framingham perspective
    P W F Wilson
    EPICORE, Emory University School of Medicine, Atlanta, GA, USA
    Int J Obes (Lond) 32:S17-20. 2008
  4. doi request reprint Prediction of first events of coronary heart disease and stroke with consideration of adiposity
    Peter W F Wilson
    EPICORE, Emory University School of Medicine, Atlanta, GA 30306, USA
    Circulation 118:124-30. 2008
  5. doi request reprint Low-cost strategies to predict cardiovascular disease
    Peter W F Wilson
    Emory University, Atlanta, GA 30306, USA
    Nat Clin Pract Cardiovasc Med 5:518-9. 2008
  6. doi request reprint Risk scores for prediction of coronary heart disease: an update
    Peter W F Wilson
    Division of Cardiology, Emory University School of Medicine, EPICORE, Suite 1 North, 1256 Briarcliff Road, Atlanta, GA 30306, USA
    Endocrinol Metab Clin North Am 38:33-44. 2009
  7. pmc C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study
    Peter W F Wilson
    EPICORE, Emory University School of Medicine, and the Atlanta VAMC Epidemiology and Genetics Section, Atlanta, GA 30306, USA
    Circ Cardiovasc Qual Outcomes 1:92-7. 2008
  8. doi request reprint Evidence of systemic inflammation and estimation of coronary artery disease risk: a population perspective
    Peter W F Wilson
    Cardiology Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30306 2636, USA
    Am J Med 121:S15-20. 2008
  9. ncbi request reprint Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study
    Peter W F Wilson
    Emory Program in Cardiovascular Outcomes Research and Epidemiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Arch Intern Med 167:1068-74. 2007
  10. doi request reprint Attained educational level and incident atherothrombotic events in low- and middle-income compared with high-income countries
    Abhinav Goyal
    Emory Rollins School of Public Health, 1518 Clifton Road NE, Atlanta, GA 30322, USA
    Circulation 122:1167-75. 2010

Detail Information

Publications80

  1. doi request reprint An international model to predict recurrent cardiovascular disease
    Peter W F Wilson
    Atlanta VA Medical Center and Cardiology Division, Emory University School of Medicine, GA, USA
    Am J Med 125:695-703.e1. 2012
    ..Prediction models for cardiovascular events and cardiovascular death in patients with established cardiovascular disease are not generally available...
  2. doi request reprint Prediction of cardiovascular disease events
    Peter W F Wilson
    Atlanta VAMC Epidemiology and Genetics Section, Emory Clinical Cardiovascular Research Institute, Atlanta, GA 30322, USA
    Cardiol Clin 29:1-13. 2011
    ..Performance criteria for risk estimation include discrimination, calibration, and reclassification, and newer heart disease risk factors and biomarkers can be evaluated in the context of existing risk estimation approaches...
  3. doi request reprint Cardiometabolic risk: a Framingham perspective
    P W F Wilson
    EPICORE, Emory University School of Medicine, Atlanta, GA, USA
    Int J Obes (Lond) 32:S17-20. 2008
    ..To review published data on vascular disease- and diabetes-related outcomes related to adiposity and metabolic risk factors...
  4. doi request reprint Prediction of first events of coronary heart disease and stroke with consideration of adiposity
    Peter W F Wilson
    EPICORE, Emory University School of Medicine, Atlanta, GA 30306, USA
    Circulation 118:124-30. 2008
    ..Previous reports have focused on traditional cardiovascular risk factors; less information has been available on the role of overweight and obesity...
  5. doi request reprint Low-cost strategies to predict cardiovascular disease
    Peter W F Wilson
    Emory University, Atlanta, GA 30306, USA
    Nat Clin Pract Cardiovasc Med 5:518-9. 2008
    ..Strategies such as these might enhance screening and prevention programs but require validation. Testing the usefulness of low-cost prediction models in developing regions is the next logical step in carrying this concept forward...
  6. doi request reprint Risk scores for prediction of coronary heart disease: an update
    Peter W F Wilson
    Division of Cardiology, Emory University School of Medicine, EPICORE, Suite 1 North, 1256 Briarcliff Road, Atlanta, GA 30306, USA
    Endocrinol Metab Clin North Am 38:33-44. 2009
    ....
  7. pmc C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study
    Peter W F Wilson
    EPICORE, Emory University School of Medicine, and the Atlanta VAMC Epidemiology and Genetics Section, Atlanta, GA 30306, USA
    Circ Cardiovasc Qual Outcomes 1:92-7. 2008
    ..The relationship of circulating levels of high-sensitivity C-reactive protein (CRP) with cardiovascular disease (CVD) risk, particularly with consideration of effects at intermediate levels of risk, has not been fully assessed...
  8. doi request reprint Evidence of systemic inflammation and estimation of coronary artery disease risk: a population perspective
    Peter W F Wilson
    Cardiology Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30306 2636, USA
    Am J Med 121:S15-20. 2008
    ....
  9. ncbi request reprint Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study
    Peter W F Wilson
    Emory Program in Cardiovascular Outcomes Research and Epidemiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Arch Intern Med 167:1068-74. 2007
    ..Prediction rules for type 2 diabetes mellitus (T2DM) have been developed, but we lack consensus for the most effective approach...
  10. doi request reprint Attained educational level and incident atherothrombotic events in low- and middle-income compared with high-income countries
    Abhinav Goyal
    Emory Rollins School of Public Health, 1518 Clifton Road NE, Atlanta, GA 30322, USA
    Circulation 122:1167-75. 2010
    ..However, most of these studies have been conducted in high-income countries (HICs) and lack representation from low- and middle-income countries (LMICs), which bear >80% of the global burden of cardiovascular disease...
  11. pmc Insulin therapy in acute coronary syndromes: an appraisal of completed and ongoing randomised trials with important clinical end points
    Abhinav Goyal
    Department of Epidemiology, Emory Rollins School of Public Health, Atlanta, GA, USA
    Diab Vasc Dis Res 5:276-84. 2008
    ....
  12. pmc Diabetes care in black and white veterans in the southeastern U.S
    Jennifer G Twombly
    Division of Endocrinology and Metabolism, Emory University School of Medicine, Atlanta, Georgia, USA
    Diabetes Care 33:958-63. 2010
    ..We investigated whether there were differences in diabetes care in the Veterans Administration (VA), where health care access should be relatively uniform...
  13. pmc Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study
    Javed Butler
    Emory University, Atlanta GA, USA
    Arterioscler Thromb Vasc Biol 29:1144-9. 2009
    ..We investigated the association of serum resistin concentrations with risk for incident heart failure (HF) in humans...
  14. doi request reprint Improved near-term coronary artery disease risk classification with gated stress myocardial perfusion SPECT
    Leslee J Shaw
    Emory University School of Medicine, Atlanta, Georgia, USA
    JACC Cardiovasc Imaging 3:1139-48. 2010
    ..We compared analytical approaches to estimate the added value of myocardial perfusion single-photon emission computed tomography (MPS) variables in estimating coronary artery disease (CAD) outcomes...
  15. pmc Predictors of incident heart failure in a large insured population: a one million person-year follow-up study
    Abhinav Goyal
    Emory Rollins School of Public Health, 1518 Clifton Road NE, Atlanta, GA 30322, USA
    Circ Heart Fail 3:698-705. 2010
    ..Studies on the incidence and predictors of heart failure (HF) are often restricted to elderly persons or identify only inpatient cases...
  16. pmc Epidemiology of incident heart failure in a contemporary elderly cohort: the health, aging, and body composition study
    Andreas Kalogeropoulos
    Cardiology Division, Emory University Hospital, Emory University, 1365 Clifton Rd NE, Ste AT430, Atlanta, GA 30322, USA
    Arch Intern Med 169:708-15. 2009
    ..The race- and sex-specific epidemiology of incident heart failure (HF) among a contemporary elderly cohort are not well described...
  17. pmc Validation of the health ABC heart failure model for incident heart failure risk prediction: the Cardiovascular Health Study
    Andreas Kalogeropoulos
    Department of Medicine, Division of Cardiology, Emory University, Atlanta, GA 30322, USA
    Circ Heart Fail 3:495-502. 2010
    ..The recently developed and internally validated Health ABC HF model uses 9 routinely available clinical variables to determine incident heart failure risk. In this study, we sought to externally validate the Health ABC HF model...
  18. ncbi request reprint The REduction of Atherothrombosis for Continued Health (REACH) Registry: an international, prospective, observational investigation in subjects at risk for atherothrombotic events-study design
    E Magnus Ohman
    Division of Cardiology, Duke University Medical Center, Durham, NC, USA
    Am Heart J 151:786.e1-10. 2006
    ....
  19. pmc Glycemic status and incident heart failure in elderly without history of diabetes mellitus: the health, aging, and body composition study
    Andreas Kalogeropoulos
    Emory University, Atlanta, GA, USA
    J Card Fail 15:593-9. 2009
    ..It is unclear whether measures of glycemic status beyond fasting glucose (FG) levels improve incident heart failure (HF) prediction in patients without history of diabetes mellitus (DM)...
  20. ncbi request reprint Comparison of prognostic usefulness of coronary artery calcium in men versus women (results from a meta- and pooled analysis estimating all-cause mortality and coronary heart disease death or myocardial infarction)
    Antonio Bellasi
    Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Cardiol 100:409-14. 2007
    ..66), suggesting an equivalent ability to risk stratify by gender. In conclusion, this meta- and pooled analysis revealed that CAC screening is equally accurate in stratifying risk in women and men...
  21. ncbi request reprint Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: results from the third National Health and Nutrition Examination Survey
    Suzanne E Judd
    Nutrition and Health Sciences Program, Graduate Division of Biological and Biomedical Sciences and Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Am J Clin Nutr 87:136-41. 2008
    ..The prevalences of both hypertension and vitamin D insufficiency are high in the United States. Recent clinical trials and animal studies have suggested that vitamin D insufficiency may be associated with elevated blood pressure...
  22. ncbi request reprint Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham Study
    David S Freedman
    Division of Nutrition and Physical Activity, CDC, Atlanta, GA, USA
    Clin Chem 50:1189-200. 2004
    ..We examined whether this differential CHD risk might, in part, be attributable to the sizes of lipoprotein particles or concentrations of lipoprotein subclasses...
  23. doi request reprint Obesity: why be concerned?
    W Virgil Brown
    Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia 30033, USA
    Am J Med 122:S4-11. 2009
    ....
  24. pmc Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease
    Martin K Rutter
    Cardiovascular Research Group, Division of Cardiovascular and Endocrine Sciences, University of Manchester, and The Manchester Diabetes Centre, Manchester Royal Infirmary, Manchester, United Kingdom
    Circulation 117:1003-9. 2008
    ....
  25. ncbi request reprint Clinical trial issues in weight-loss therapy
    Manesh R Patel
    Duke University Medical Center, Durham, NC 27708, USA
    Am Heart J 151:633-42. 2006
    ..Effective obesity therapies also have the potential for off-label use and unintended consequences...
  26. ncbi request reprint Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level
    Sekar Kathiresan
    Framingham Heart Study, Framingham, MA 01702 5827, USA
    Circulation 113:1415-23. 2006
    ..Serum C-reactive protein (CRP) level is a heritable complex trait that predicts incident cardiovascular disease. We investigated the clinical and genetic sources of interindividual variability in serum CRP...
  27. ncbi request reprint Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease
    James B Meigs
    General Medicine Division, Massachusetts General Hospital, 50 Staniford Street, 9th Floor, Boston, MA 02114, USA
    J Clin Endocrinol Metab 91:2906-12. 2006
    ..Metabolic risk conferred by adiposity may be due to associated risk factor clustering...
  28. ncbi request reprint PAI-1 Gene 4G/5G polymorphism and risk of type 2 diabetes in a population-based sample
    James B Meigs
    General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Obesity (Silver Spring) 14:753-8. 2006
    ..Elevated PAI-1 levels may be associated with an increased risk for diabetes as a marker for underlying endothelial dysfunction rather than by a direct effect of genetically mediated elevated levels...
  29. ncbi request reprint Magnesium intake is related to improved insulin homeostasis in the framingham offspring cohort
    Marcella E Rumawas
    Nutritional Epidemiology Program, JM USDA HNRC at Tufts University, Boston, MA 02111 1524, USA
    J Am Coll Nutr 25:486-92. 2006
    ..Higher dietary intake of magnesium may protect against development of type 2 diabetes. The aim of this study was to examine the association between dietary magnesium intake and metabolic risk factors for diabetes...
  30. ncbi request reprint Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome
    James B Meigs
    Harvard Medical School and the General Medicine Division, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
    Diabetes Care 30:1219-25. 2007
    ..Metabolic syndrome increases the risk for type 2 diabetes and cardiovascular disease (CVD) and may be associated with insulin resistance...
  31. ncbi request reprint The significant effect of diabetes duration on coronary heart disease mortality: the Framingham Heart Study
    Caroline S Fox
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702, USA
    Diabetes Care 27:704-8. 2004
    ..We hypothesized that duration of diabetes is an important predictor of incident CHD among people with diabetes...
  32. pmc A coronary heart disease risk score based on patient-reported information
    Arch G Mainous
    Department of Family Medicine, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Cardiol 99:1236-41. 2007
    ..69, p = 0.01). In conclusion, the Personal HEART score identifies 10-year risk for CHD based on self-report data, is similar in predictive ability to the FRS and European SCORE, and has the potential for easy self-assessment...
  33. ncbi request reprint Cardiovascular risk assessment--where are we going?
    Peter W F Wilson
    American Society of Preventive Cardiology
    Prev Cardiol 11:183-4. 2008
  34. ncbi request reprint A likely explanation for the J-curve of blood pressure cardiovascular risk
    William B Kannel
    Boston University School of Medicine Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    Am J Cardiol 94:380-4. 2004
    ..Patients with this condition of isolated systolic hypertension have been shown to benefit from antihypertensive treatment...
  35. pmc Differences in cardiovascular disease mortality associated with body mass between Black and White persons
    Jill E Abell
    Medical University of South Carolina, Charleston, SC 29401, USA
    Am J Public Health 98:63-6. 2008
    ..91 (95% CI=0.77, 1.05), respectively. The results suggest that obesity is an independent risk factor in White people, and additional study of body size and disease progression is necessary in the assessment of racial disparities...
  36. pmc C-reactive protein, inflammatory conditions, and cardiovascular disease risk
    Ravi Dhingra
    National Heart Lung and Blood Institute s NHBLI Framingham Heart Study, Framingham, Mass 01702 5827, USA
    Am J Med 120:1054-62. 2007
    ..It is uncertain to what extent high C-reactive protein (CRP) concentrations reflect the presence of inflammatory conditions in the community...
  37. pmc Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study
    Caroline S Fox
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Diabetes Care 31:1582-4. 2008
    ..We assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes...
  38. doi request reprint BMI vs. waist circumference for identifying vascular risk
    Matthew S Freiberg
    Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Obesity (Silver Spring) 16:463-9. 2008
    ..0 and 34.9 kg/m(2). We investigated the relative contributions of BMI and WC toward identifying risk of adverse vascular events in a community-based sample...
  39. ncbi request reprint Hemostatic markers of endothelial dysfunction and risk of incident type 2 diabetes: the Framingham Offspring Study
    James B Meigs
    General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
    Diabetes 55:530-7. 2006
    ..09-1.77). We conclude that in this community-based sample, plasma markers of endothelial dysfunction increased risk of incident diabetes independent of other diabetes risk factors including obesity, insulin resistance, and inflammation...
  40. ncbi request reprint Assessing coronary heart disease risk with traditional and novel risk factors
    Peter W F Wilson
    Department of Endocrinology, Diabetes, and Medical Geriatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Cardiol 27:III7-11. 2004
    ..Assessment of global risk is particularly important in lipid management, as the LDL-C target goals are determined by risk category...
  41. ncbi request reprint Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?
    Paul M Ridker
    Donald W Reynolds Center for Cardiovascular Research, Boston, Mass, USA
    Circulation 109:2818-25. 2004
    ..Toward this end, we believe experts in the fields of epidemiology, prevention, vascular biology, and clinical cardiology should be convened to begin discussing the merits of this proposal...
  42. ncbi request reprint Plasma natriuretic peptides for community screening for left ventricular hypertrophy and systolic dysfunction: the Framingham heart study
    Ramachandran S Vasan
    National Heart, Lung, and Blood Institute s Framingham Heart Study, 73 Mt Wayte Ave, Suite 2, Framingham, MA 01702, USA
    JAMA 288:1252-9. 2002
    ..Prior studies were limited by small sample sizes and selection bias and none compared the diagnostic performance of these peptides in men and women...
  43. ncbi request reprint Risk stratification of obesity as a coronary risk factor
    William B Kannel
    Framingham Study, Boston University School of Medicine, Framingham, Massachusetts, USA
    Am J Cardiol 90:697-701. 2002
    ..Global risk assessment can identify high-risk overweight candidates for CHD who most urgently need correction of associated risk factors, as well as sustained weight reduction...
  44. ncbi request reprint Impact of obesity on plasma natriuretic peptide levels
    Thomas J Wang
    Framingham Heart Study, Framingham, Mass 01702, USA
    Circulation 109:594-600. 2004
    ..The natriuretic peptides are important regulators of sodium homeostasis and neurohormonal activation, raising the possibility that obese individuals have an impaired natriuretic peptide response...
  45. ncbi request reprint Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study
    John F Keaney
    Evans Memorial Department of Medicine, Boston University School of Medicine, Whitaker Cardiovascular Institute, 715 Albany St, Rm W507, Boston, MA 02118, USA
    Arterioscler Thromb Vasc Biol 23:434-9. 2003
    ..Thus, it has been difficult to evaluate the relative contribution of each cardiovascular risk factor to systemic oxidative stress and to determine whether such risk factors act independently and are applicable to the general population...
  46. ncbi request reprint Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study
    Ramachandran S Vasan
    Framingham Heart Study, Framingham, Mass 01702 5803, USA
    Circulation 107:1486-91. 2003
    ..It is unclear whether cytokine levels can predict the incidence of CHF in asymptomatic individuals...
  47. ncbi request reprint Overweight and obesity as determinants of cardiovascular risk: the Framingham experience
    Peter W F Wilson
    Boston University School of Medicine, 715 Albany St, Evans 204, Boston, MA 02118, USA
    Arch Intern Med 162:1867-72. 2002
    ..To our knowledge, no single investigation concerning the long-term effects of overweight status on the risk for hypertension, hypercholesterolemia, diabetes mellitus, and cardiovascular sequelae has been reported...
  48. ncbi request reprint Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort
    Nicola M McKeown
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    Diabetes Care 27:538-46. 2004
    ..The aim of this study was to examine the relation between carbohydrate-related dietary factors, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort...
  49. ncbi request reprint Insulin resistance syndrome and the prothrombotic state: a Framingham perspective
    Peter W F Wilson
    Endocr Pract 9:50-2. 2003
  50. ncbi request reprint Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies
    James B Meigs
    Department of Medicine, General Medicine Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 52:2160-7. 2003
    ..S. By any criteria, subjects with the metabolic syndrome are more insulin resistant and at increased predicted risk for CHD versus those without the metabolic syndrome...
  51. ncbi request reprint The metabolic syndrome: practical guide to origins and treatment: Part I
    Peter W F Wilson
    Framingham Heart Study of the National Heart, Blood, and Lung Institute, Boston, Mass, USA
    Circulation 108:1422-4. 2003
  52. ncbi request reprint Concept and usefulness of cardiovascular risk profiles
    William B Kannel
    National Heart, Lung, and Blood Institute s Framingham Study, National Institutes of Health, Boston University School of Medicine, Framingham, Mass 01702, USA
    Am Heart J 148:16-26. 2004
    ..Multivariable risk stratification is now recognized as essential in efficiently identifying likely candidates for CVD and quantifying the hazard...
  53. ncbi request reprint Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study
    Nicola M McKeown
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 76:390-8. 2002
    ..The influence of whole grains on cardiovascular disease risk may be mediated through multiple pathways, eg, a reduction in blood lipids and blood pressure, an enhancement of insulin sensitivity, and an improvement in blood glucose control...
  54. ncbi request reprint C-reactive protein and risk of cardiovascular disease in men and women from the Framingham Heart Study
    Peter W F Wilson
    General Clinical Research Center, Medical University of South Carolina, Charleston 29425, USA
    Arch Intern Med 165:2473-8. 2005
    ..Determination of C-reactive protein (CRP) level has been suggested to improve cardiovascular disease (CVD) risk assessment. This study examines the utility of CRP levels to assess CVD risk in a community setting...
  55. ncbi request reprint Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus
    Peter W F Wilson
    The NHLBI s Framingham Heart Study, Framingham, Massachusetts, USA
    Circulation 112:3066-72. 2005
    ..The objective was to investigate risk for CVD, CHD, and T2DM according to metabolic syndrome traits...
  56. ncbi request reprint Cardiac rehabilitation and getting to lipid goals
    Peter W F Wilson
    J Cardiopulm Rehabil 25:264-5. 2005
  57. ncbi request reprint Estimating the risk for atherothrombosis: are current approaches sufficient?
    Peter W F Wilson
    General Clinical Research Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Eur J Cardiovasc Prev Rehabil 12:427-32. 2005
    ....
  58. ncbi request reprint CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: ability of inflammatory markers to predict disease in asymptomatic patients: a background paper
    Peter W F Wilson
    Circulation 110:e568-71. 2004
    ....
  59. ncbi request reprint The insulin gene variable number tandem repeat and risk of type 2 diabetes in a population-based sample of families and unrelated men and women
    James B Meigs
    General Medicine Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 90:1137-43. 2005
    ..These data support the hypothesis that the INS VNTR is a genetic risk factor for type 2 diabetes, with the TT genotype accounting for about 6.6% of cases in the FHS population...
  60. ncbi request reprint Obesity, diabetes, and risk of cardiovascular disease in the elderly
    Peter W F Wilson
    Department of Medicine, Boston University Medical School, Boston, MA 02118, USA
    Am J Geriatr Cardiol 11:119-23,125. 2002
    ..Trial data indicate that preventive measures benefit obese diabetics even more than nondiabetics...
  61. ncbi request reprint C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study
    Martin K Rutter
    Countess of Chester Hospital, Chester, UK
    Circulation 110:380-5. 2004
    ..Inflammation (assessed by C-reactive protein [CRP]) and the metabolic syndrome (MetS) are associated with cardiovascular disease (CVD), but population-based data are limited...
  62. ncbi request reprint Elevated remnant-like particle cholesterol and triglyceride levels in diabetic men and women in the Framingham Offspring Study
    Ernst J Schaefer
    Lipid Research Laboratory, Division of Endocrinology, Diabetes, Metabolism, and Molecular Medicine, New England Medical Center, Boston, Massachusetts 02111, USA
    Diabetes Care 25:989-94. 2002
    ..We hypothesized that diabetic patients would have higher remnant levels than nondiabetic patients...
  63. ncbi request reprint Heritability and correlates of intercellular adhesion molecule-1 in the Framingham Offspring Study
    John F Keaney
    Evans Memorial Department of Medicine, Boston University School of Medicine, Massachusetts 02118, USA
    J Am Coll Cardiol 44:168-73. 2004
    ..We sought to determine the clinical factors and heritability associated with inflammation measured as circulating levels of soluble-intercellular adhesion molecule-1 (sICAM-1) in a community-based cohort...
  64. ncbi request reprint American College of Endocrinology position statement on the insulin resistance syndrome
    Daniel Einhorn
    American College of Endocrinology
    Endocr Pract 9:237-52. 2003
  65. pmc Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistance
    Marie France Hivert
    Department of Medicine, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 93:3165-72. 2008
    ..Adipose tissue-derived adipokines may contribute to insulin resistance...
  66. ncbi request reprint Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study
    Zaldy Sy Tan
    Division on Aging, Harvard Medical School, Boston, MA, USA
    Arch Intern Med 163:1053-7. 2003
    ..We examined the impact of baseline and lifetime plasma total cholesterol levels averaged across many years on the risk for AD in a large, population-based cohort...
  67. ncbi request reprint Coronary artery calcification in type 2 diabetes and insulin resistance: the framingham offspring study
    James B Meigs
    General Medicine Division and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Diabetes Care 25:1313-9. 2002
    ....
  68. ncbi request reprint The ankle-brachial index in the elderly and risk of stroke, coronary disease, and death: the Framingham Study
    Joanne M Murabito
    National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Framingham, MA 01702 5827, USA
    Arch Intern Med 163:1939-42. 2003
    ..Limited data exist regarding the relation between a low ABI and stroke. We sought to examine the relation between a low ABI and stroke, coronary heart disease, and death in the elderly...
  69. ncbi request reprint Framingham and European risk algorithms: implications for African Americans
    Peter W F Wilson
    General Clinical Research Center, Medical University of South Carolina, Charleston, South Carolina, USA
    Rev Cardiovasc Med 5:S34-41. 2004
    ..Estimation of risk for cardiovascular events is a dynamic field, and current approaches will likely be modified as newer information is obtained...
  70. ncbi request reprint Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study
    Sekar Kathiresan
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    Circulation 113:20-9. 2006
    ..However, the atherogenic potential of LDL may depend on the number and size of LDL particles in addition to the cholesterol content of LDL...
  71. ncbi request reprint Clinical utility of different lipid measures for prediction of coronary heart disease in men and women
    Erik Ingelsson
    Framingham Heart Study, 73 Mount Wayte Ave, Suite 2, Framingham, MA 01702 5803
    JAMA 298:776-85. 2007
    ..Evidence is conflicting regarding the performance of apolipoproteins vs traditional lipids for predicting coronary heart disease (CHD) risk...
  72. ncbi request reprint Association between obesity and a prothrombotic state: the Framingham Offspring Study
    Guido A Rosito
    Hospital Clinicas, Porto Alegre, Brazil
    Thromb Haemost 91:683-9. 2004
    ..The association between increased body mass index and waist-to-hip ratio and prothrombotic factors and impaired fibrinolysis suggests that obesity is a risk factor whose effect is mediated in part by a prothrombotic state...
  73. ncbi request reprint Accuracy of offspring reports of parental cardiovascular disease history: the Framingham Offspring Study
    Joanne M Murabito
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    Ann Intern Med 140:434-40. 2004
    ..Family history is used to infer the risk for heart disease; however, little is known about the accuracy of family history reports...
  74. ncbi request reprint Relations of serum aldosterone to cardiac structure: gender-related differences in the Framingham Heart Study
    Ramachandran S Vasan
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Bethesda, MD, USA
    Hypertension 43:957-62. 2004
    ..Additional investigations are warranted to confirm these findings...
  75. ncbi request reprint 34th Bethesda Conference: Task force #1--Identification of coronary heart disease risk: is there a detection gap?
    Richard C Pasternak
    Preventive Cardiology and Cardiac Rehabilitation, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114 2620, USA
    J Am Coll Cardiol 41:1863-74. 2003
  76. ncbi request reprint Anticardiolipin antibodies and risk of ischemic stroke and transient ischemic attack: the Framingham cohort and offspring study
    Vallabh Janardhan
    Department of Neurology, Boston University, Boston, Mass, USA
    Stroke 35:736-41. 2004
    ..Prior cohort studies included only selected subjects, mostly men. We related serum concentrations of aCLs to incident first ischemic stroke/TIA among men and women in the Framingham Heart Study cohort and offspring...
  77. doi request reprint CETP genes, metabolic effects, and coronary disease risk
    Peter W F Wilson
    JAMA 299:2795-6. 2008
  78. pmc Development of appropriate coronary heart disease risk prediction models in HIV-infected patients
    Morris Schambelan
    Circulation 118:e48-53. 2008
  79. ncbi request reprint Obesity modulates the association among APOE genotype, insulin, and glucose in men
    Roberto Elosua
    Nutrition and Genomics Laboratory and Lipid Metabolism Laboratory, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Obes Res 11:1502-8. 2003
    ..Obesity, insulin resistance, and apolipoprotein E (APOE) genotype have all been associated with coronary heart disease. We examined the interaction between obesity and APOE genotype in determining fasting insulin and glucose levels...
  80. ncbi request reprint Relative importance of borderline and elevated levels of coronary heart disease risk factors
    Ramachandran S Vasan
    Framingham Heart Study, Framingham, Massachusetts 01702 5803, USA
    Ann Intern Med 142:393-402. 2005
    ..Clinical trials indicate that a sizable proportion of adults have multiple borderline coronary risk factors and may benefit from treatment...