Research Topics
| Elaine WalkerSummaryAffiliation: Emory University Country: USA Publications
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Detail Information
Publications
Stress and the prodromal phase of psychosisCarrie W Holtzman
Emory University Atlanta, GA 30322, USA
Curr Pharm Des 18:527-33. 2012....- Pubertal neurodevelopment and the emergence of psychotic symptomsElaine Walker
Department of Psychology, Emory University, Atlanta, GA 30322, USA
Schizophr Res 54:17-23. 2002..We then consider how postpubertal hormone changes might serve to trigger the expression of vulnerability genes that code for abnormal brain development... 
Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophreniaElaine Walker
Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
Annu Rev Clin Psychol 4:189-216. 2008....
The relation of antipsychotic and antidepressant medication with baseline symptoms and symptom progression: a naturalistic study of the North American Prodrome Longitudinal SampleElaine F Walker
Department of Psychology, Emory University, Atlanta, GA 30322, USA
Schizophr Res 115:50-7. 2009..The results are discussed in light of the relative risks and benefits of preventive interventions, both medication and cognitive therapies, and the importance of future clinical trials...- Pubertal neuromaturation, stress sensitivity, and psychopathologyElaine F Walker
Department of Psychology, Emory University, Atlanta, GA 30322, USA
Dev Psychopathol 16:807-24. 2004..Implications for adult psychopathology and preventive intervention are discussed... - Longitudinal changes in cortisol secretion and conversion to psychosis in at-risk youthElaine F Walker
Department of Psychology, Emory University, Atlanta, GA 30322, USA
J Abnorm Psychol 119:401-8. 2010..Future research with larger samples is needed to confirm and extend these results... - Schizophrenia: etiology and courseElaine Walker
Department of Psychology and Department of Psychiatry and Behavioral Science, Emory University, Atlanta, Georgia 30322, USA
Annu Rev Psychol 55:401-30. 2004..Subsequent neuromaturational processes, especially those that occur during adolescence, and exposure to stressful events can trigger the behavioral expression of this vulnerability... - Markers of basal ganglia dysfunction and conversion to psychosis: neurocognitive deficits and dyskinesias in the prodromal periodVijay A Mittal
Department of Psychology, University of California Los Angeles, Los Angeles, California, USA
Biol Psychiatry 68:93-9. 2010.... - Physical manifestations of neurodevelopmental disruption: are minor physical anomalies part of the syndrome of schizophrenia?Michael T Compton
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 49 Jesse Hill Jr Drive, SE, Room No 333, Atlanta, GA 30303, USA
Schizophr Bull 35:425-36. 2009.... - Lack of support for the inability to taste phenylthiocarbamide as an endophenotypic marker in patients with schizophrenia and their first-degree relativesMichael T Compton
Emory University School of Medicine, 49 Jesse Hill Jr Drive, S E, Room 333, Atlanta, GA 30303, USA
Schizophr Res 95:65-9. 2007..Associations between PTC-tasting status and olfactory identification scores also were examined... - Nicotine consumption and schizotypy in first-degree relatives of individuals with schizophrenia and non-psychiatric controlsMichelle L Esterberg
Emory University Graduate School of Arts and Sciences, Department of Psychology, 1462 Clifton Road, Suite 235, Atlanta, GA 30322, United States
Schizophr Res 97:6-13. 2007.... - The relation of cortisol levels with hippocampus volumes under baseline and challenge conditionsKevin D Tessner
Department of Psychology, Emory University, Atlanta, GA 30322, USA
Brain Res 1179:70-8. 2007..e. under baseline conditions). The present findings are consistent with other evidence that the hippocampus, as reflected in volume, partially determines the efficacy of negative feedback in modulating cortisol levels... - Movement abnormalities predict conversion to Axis I psychosis among prodromal adolescentsVijay A Mittal
Department of Psychology, Emory University, Atlanta, GA 30322, USA
J Abnorm Psychol 116:796-803. 2007..The implications for neural mechanisms and for identifying candidates for preventive intervention are discussed... - Longitudinal progression of movement abnormalities in relation to psychotic symptoms in adolescents at high risk of schizophreniaVijay A Mittal
Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
Arch Gen Psychiatry 65:165-71. 2008..To date, there have been no published longitudinal studies examining the progression of movement abnormalities and their relation with symptom progression in at-risk youth... - Patient-level predictors and clinical correlates of duration of untreated psychosis among hospitalized first-episode patientsMichael T Compton
Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, 49 Jesse Hill Jr Drive, SE, Room 333, Atlanta, GA 30303, USA
J Clin Psychiatry 72:225-32. 2011..This study examined patient-level predictors of DUP and clinical correlates of both DUP and duration of untreated illness (DUI), both of which have been implicated as prognostic indicators... - Maternal depression and infant cortisol: influences of timing, comorbidity and treatmentPatricia A Brennan
Psychology Department, Emory University, Atlanta, GA 30322, USA
J Child Psychol Psychiatry 49:1099-107. 2008..The potential roles of comorbid maternal anxiety disorders, timing of maternal depression, and maternal treatment with psychotropic medications during pregnancy are addressed... - Childhood and current autistic features in adolescents with schizotypal personality disorderMichelle L Esterberg
Emory University Graduate School of Arts and Sciences, Department of Psychology, United States, 1462 Clifton Road, Suite 235, Atlanta, GA 30322, United States
Schizophr Res 104:265-73. 2008..The findings indicate that past and current autistic signs are more common in adolescents with SPD, but neither current nor childhood autistic features are linked with conversion to psychosis... - Early signs, diagnosis and therapeutics of the prodromal phase of schizophrenia and related psychotic disordersMolly K Larson
Emory University, Department of Psychology, Atlanta, GA, USA
Expert Rev Neurother 10:1347-59. 2010..Findings support further research for the establishment of best-practice standards... - Association of pre-onset cannabis, alcohol, and tobacco use with age at onset of prodrome and age at onset of psychosis in first-episode patientsMichael T Compton
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30303, USA
Am J Psychiatry 166:1251-7. 2009..Effects of the progression of frequency of use were examined through time-dependent covariates in survival analyses... - The impact of a family history of psychosis on age-at-onset and positive and negative symptoms of schizophrenia: a meta-analysisMichelle L Esterberg
Emory University Graduate School of Arts and Sciences, Department of Psychology, 36 Eagle Row, Atlanta, Georgia 30322, USA
Schizophr Res 120:121-30. 2010..Implications of the current findings, limitations of the review, and directions for future research are highlighted... - Characteristics of the retrospectively assessed prodromal period in hospitalized patients with first-episode nonaffective psychosis: findings from a socially disadvantaged, low-income, predominantly African American populationMichael T Compton
Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, 49 Jesse Hill Jr Drive, SE, Room 333, Atlanta, GA 30303, USA
J Clin Psychiatry 71:1279-85. 2010..This study describes the prodromal period of 109 hospitalized first-episode patients from an urban, socially disadvantaged, predominantly African American population... - Elevated social Internet use and schizotypal personality disorder in adolescentsVijay A Mittal
Emory University, Psychology, Department of Psychology, 235 Dental Building, 1462 Clifton Road, Atlanta, GA 30322, USA
Schizophr Res 94:50-7. 2007.... - Movement abnormalities and the progression of prodromal symptomatology in adolescents at risk for psychotic disordersVijay A Mittal
Department of Psychology, Emory University, Atlanta, GA 30322, USA
J Abnorm Psychol 116:260-7. 2007..Within the SPD group, baseline movement abnormalities predicted symptom severity 1 year later. Movement abnormalities represent an early risk indicator that may be predictive of later symptom severity and potentially of psychosis onset... - Gesture behavior in unmedicated schizotypal adolescentsVijay A Mittal
Department of Psychology, Emory University, Atlanta, GA 30322, USA
J Abnorm Psychol 115:351-8. 2006..The findings are discussed in light of brain regions involved in dysfunction, parallels to schizophrenia, and treatment implications... - Cortisol responses of healthy volunteers undergoing magnetic resonance imagingKevin D Tessner
Emory University Psychological Center, Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
Hum Brain Mapp 27:889-95. 2006..The implications for neuroimaging studies are discussed... - Associations between olfactory identification and verbal memory in patients with schizophrenia, first-degree relatives, and non-psychiatric controlsMichael T Compton
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
Schizophr Res 86:154-66. 2006.... - The relations among putative biorisk markers in schizotypal adolescents: minor physical anomalies, movement abnormalities, and salivary cortisolVijay A Mittal
Emory University, Department of Psychology, Atlanta, Georgia 30322, USA
Biol Psychiatry 61:1179-86. 2007.... - The influence of perceived control and locus of control on the cortisol and subjective responses to stressAnnie M Bollini
Emory University, 1462 Clifton Road, Suite 235, Atlanta, GA 30322, USA
Biol Psychol 67:245-60. 2004..The results are discussed in light of their implications for elucidating the determinants of the effects of perceived control on stress... - Observations on parent/family factors that may influence the duration of untreated psychosis among African American first-episode schizophrenia-spectrum patientsMichael T Compton
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Grady Memorial Hospital, Box 26238, 80 Jesse Hill Jr Drive, S E, Atlanta, GA 30303, USA
Schizophr Res 68:373-85. 2004..These preliminary observations may serve to generate hypotheses for further research that aims to elucidate the determinants of treatment delays in the early course of schizophrenia, especially among African American populations... - Facial measurement differences between patients with schizophrenia and non-psychiatric controlsMichael T Compton
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 101 Woodruff Circle, Suite 4000, Atlanta, Georgia, 30322, United States
Schizophr Res 93:245-52. 2007..differ from controls in terms of a number of specific facial measurements?, and (2) Does cluster analysis based on these facial measurements reveal distinct facial morphologies that significantly discriminate patients from controls?.. - Neurological soft signs and minor physical anomalies in patients with schizophrenia and related disorders, their first-degree biological relatives, and non-psychiatric controlsMichael T Compton
Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, 49 Jesse Hill Jr Drive, S E, Room 333, Atlanta, GA 30303, United States
Schizophr Res 94:64-73. 2007.... - Factor structure of the Neurological Evaluation Scale in a predominantly African American sample of patients with schizophrenia, unaffected relatives, and non-psychiatric controlsMichael T Compton
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 49 Jesse Hill Jr Drive, S E, Atlanta, GA 30303, USA
Schizophr Res 84:365-77. 2006..This study aimed to identify latent factors of the most widely used scale to measure neurological soft signs, the Neurological Evaluation Scale (NES), in a sample of schizophrenia patients, their relatives, and non-psychiatric controls... - Cognitive function and symptoms in adolescents with schizotypal personality disorderHanan Trotman
Department of Psychology, Emory University, USA
Schizophr Bull 32:489-97. 2006.... - Plasma hormones and catecholamine metabolites in monozygotic twins discordant for psychosisElaine F Walker
Emory University, Atlanta, Georgia 30322, USA
Neuropsychiatry Neuropsychol Behav Neurol 15:10-7. 2002..CONCLUSION: These findings suggest the potential role of adrenal steroids and hippocampal function in the expression of psychosis... - Catechol-O-methyltransferase modulation of cortisol secretion in psychiatrically at-risk and healthy adolescentsDeborah J Walder
Department of Psychology, Brooklyn College and the Graduate Center of the City University of New York, New York 11210, USA
Psychiatr Genet 20:166-70. 2010..In addition, this study examined the relation of COMT genotype with longitudinal changes in cortisol... - Childhood videotaped social and neuromotor precursors of schizophrenia: a prospective investigationJason Schiffman
Department of Psychology, University of Hawaii at Manoa, Gartley Hall 110, 2430 Campus Road, Honolulu, HI 96822 2216, USA
Am J Psychiatry 161:2021-7. 2004..The authors examined videotaped behaviors of children who developed schizophrenia as adults and of comparison subjects to disclose possible social and neuromotor deficits foreshadowing later development of schizophrenia... - A descriptive study of pathways to care among hospitalized urban African American first-episode schizophrenia-spectrum patientsMichael T Compton
Dept. of Psychiatry, Emory University School of Medicine, Grady Memorial Hospital, Box 26238, 80 Jesse Hill Jr. Drive, S.E, Atlanta, GA 30303, USA
Soc Psychiatry Psychiatr Epidemiol 41:566-73. 2006..Such investigations may provide insights into service enhancements that can promote early detection and intervention, thus improving illness outcomes... - Neuromotor functioning in adolescents with schizotypal personality disorder: associations with symptoms and neurocognitionCraig S Neumann
Department of Psychology, University of North Texas, Denton 76203 1280, USA
Schizophr Bull 29:285-98. 2003..Differences as well as broad similarities in the pattern of motor findings between the adult and adolescent SPD studies are discussed... - Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factorDeborah J Walder
Psychology Department at Brooklyn College City University of New York, Brooklyn, NY 11210, USA
Schizophr Res 86:118-22. 2006..Diagnostic group differences were restricted to White/Caucasian males with greater right 2D:4D in SPDs. Findings suggest disruptions in prenatal gonadal hormones in vulnerability for schizophrenia... - Course of general cognitive functioning in high-risk individuals with psychosis outcomesAnnie M Bollini
Schizophr Res 79:347-8. 2005 - North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia researchJean Addington
Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada
Schizophr Bull 33:665-72. 2007.... - Associations between schizotypal features and indicators of neurological and morphological abnormalitiesAnnie M Bollini
Emory University School of Medicine, USA
Schizophr Res 92:32-40. 2007..Additionally, associations between MPA scores and schizotypy were explored in these two groups...
Research Grants
- Prediction of Psychosis in Schizotypal AdolescentsElaine Walker; Fiscal Year: 2006..In the long-term, the research holds promise for yielding findings that have implications for our conceptualization of the prodromal course of schizophrenia and other psychoses, and for approaches to preventive intervention. ..