Elaine Walker

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc Cortisol levels and risk for psychosis: initial findings from the North American prodrome longitudinal study
    Elaine F Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Biol Psychiatry 74:410-7. 2013
  2. ncbi request reprint Risk factors, and the neurodevelopmental course of schizophrenia
    E Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Eur Psychiatry 17:363s-369s. 2002
  3. ncbi request reprint Stress and the prodromal phase of psychosis
    Carrie W Holtzman
    Emory University Atlanta, GA 30322, USA
    Curr Pharm Des 18:527-33. 2012
  4. ncbi request reprint Pubertal neurodevelopment and the emergence of psychotic symptoms
    Elaine Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Schizophr Res 54:17-23. 2002
  5. pmc Longitudinal changes in cortisol secretion and conversion to psychosis in at-risk youth
    Elaine F Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    J Abnorm Psychol 119:401-8. 2010
  6. ncbi request reprint Pubertal neuromaturation, stress sensitivity, and psychopathology
    Elaine F Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Dev Psychopathol 16:807-24. 2004
  7. pmc The relation of antipsychotic and antidepressant medication with baseline symptoms and symptom progression: a naturalistic study of the North American Prodrome Longitudinal Sample
    Elaine F Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Schizophr Res 115:50-7. 2009
  8. ncbi request reprint Schizophrenia: etiology and course
    Elaine Walker
    Department of Psychology and Department of Psychiatry and Behavioral Science, Emory University, Atlanta, Georgia 30322, USA
    Annu Rev Psychol 55:401-30. 2004
  9. doi request reprint Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia
    Elaine Walker
    Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
    Annu Rev Clin Psychol 4:189-216. 2008
  10. pmc Markers of basal ganglia dysfunction and conversion to psychosis: neurocognitive deficits and dyskinesias in the prodromal period
    Vijay A Mittal
    Department of Psychology, University of California Los Angeles, Los Angeles, California, USA
    Biol Psychiatry 68:93-9. 2010

Research Grants

Detail Information

Publications44

  1. pmc Cortisol levels and risk for psychosis: initial findings from the North American prodrome longitudinal study
    Elaine F Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Biol Psychiatry 74:410-7. 2013
    ..It was hypothesized that cortisol levels would be 1) elevated in the CHR group relative to control subjects, 2) positively correlated with symptom severity, and 3) most elevated in CHR patients who transition to psychotic level severity...
  2. ncbi request reprint Risk factors, and the neurodevelopmental course of schizophrenia
    E Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Eur Psychiatry 17:363s-369s. 2002
    ..It is likely that preventive interventions for schizophrenia, be they pharmacological or behavioural, will have the best chance of success if they are directed at adolescents who are showing preschizophrenic indicators...
  3. ncbi request reprint Stress and the prodromal phase of psychosis
    Carrie W Holtzman
    Emory University Atlanta, GA 30322, USA
    Curr Pharm Des 18:527-33. 2012
    ....
  4. ncbi request reprint Pubertal neurodevelopment and the emergence of psychotic symptoms
    Elaine Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Schizophr Res 54:17-23. 2002
    ..We then consider how postpubertal hormone changes might serve to trigger the expression of vulnerability genes that code for abnormal brain development...
  5. pmc Longitudinal changes in cortisol secretion and conversion to psychosis in at-risk youth
    Elaine F Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    J Abnorm Psychol 119:401-8. 2010
    ..Future research with larger samples is needed to confirm and extend these results...
  6. ncbi request reprint Pubertal neuromaturation, stress sensitivity, and psychopathology
    Elaine F Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Dev Psychopathol 16:807-24. 2004
    ..Implications for adult psychopathology and preventive intervention are discussed...
  7. pmc The relation of antipsychotic and antidepressant medication with baseline symptoms and symptom progression: a naturalistic study of the North American Prodrome Longitudinal Sample
    Elaine F Walker
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Schizophr Res 115:50-7. 2009
    ..The results are discussed in light of the relative risks and benefits of preventive interventions, both medication and cognitive therapies, and the importance of future clinical trials...
  8. ncbi request reprint Schizophrenia: etiology and course
    Elaine Walker
    Department of Psychology and Department of Psychiatry and Behavioral Science, Emory University, Atlanta, Georgia 30322, USA
    Annu Rev Psychol 55:401-30. 2004
    ..Subsequent neuromaturational processes, especially those that occur during adolescence, and exposure to stressful events can trigger the behavioral expression of this vulnerability...
  9. doi request reprint Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia
    Elaine Walker
    Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
    Annu Rev Clin Psychol 4:189-216. 2008
    ....
  10. pmc Markers of basal ganglia dysfunction and conversion to psychosis: neurocognitive deficits and dyskinesias in the prodromal period
    Vijay A Mittal
    Department of Psychology, University of California Los Angeles, Los Angeles, California, USA
    Biol Psychiatry 68:93-9. 2010
    ....
  11. pmc Cognitive function and symptoms in adolescents with schizotypal personality disorder
    Hanan Trotman
    Department of Psychology, Emory University, USA
    Schizophr Bull 32:489-97. 2006
    ....
  12. doi request reprint The impact of a family history of psychosis on age-at-onset and positive and negative symptoms of schizophrenia: a meta-analysis
    Michelle L Esterberg
    Emory University Graduate School of Arts and Sciences, Department of Psychology, 36 Eagle Row, Atlanta, Georgia 30322, USA
    Schizophr Res 120:121-30. 2010
    ..Implications of the current findings, limitations of the review, and directions for future research are highlighted...
  13. pmc Nicotine consumption and schizotypy in first-degree relatives of individuals with schizophrenia and non-psychiatric controls
    Michelle L Esterberg
    Emory University Graduate School of Arts and Sciences, Department of Psychology, 1462 Clifton Road, Suite 235, Atlanta, GA 30322, United States
    Schizophr Res 97:6-13. 2007
    ....
  14. ncbi request reprint The relation of cortisol levels with hippocampus volumes under baseline and challenge conditions
    Kevin D Tessner
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Brain Res 1179:70-8. 2007
    ..e. under baseline conditions). The present findings are consistent with other evidence that the hippocampus, as reflected in volume, partially determines the efficacy of negative feedback in modulating cortisol levels...
  15. ncbi request reprint Movement abnormalities predict conversion to Axis I psychosis among prodromal adolescents
    Vijay A Mittal
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    J Abnorm Psychol 116:796-803. 2007
    ..The implications for neural mechanisms and for identifying candidates for preventive intervention are discussed...
  16. pmc Association of pre-onset cannabis, alcohol, and tobacco use with age at onset of prodrome and age at onset of psychosis in first-episode patients
    Michael T Compton
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30303, USA
    Am J Psychiatry 166:1251-7. 2009
    ..Effects of the progression of frequency of use were examined through time-dependent covariates in survival analyses...
  17. pmc Maternal depression and infant cortisol: influences of timing, comorbidity and treatment
    Patricia A Brennan
    Psychology Department, Emory University, Atlanta, GA 30322, USA
    J Child Psychol Psychiatry 49:1099-107. 2008
    ..The potential roles of comorbid maternal anxiety disorders, timing of maternal depression, and maternal treatment with psychotropic medications during pregnancy are addressed...
  18. doi request reprint Childhood and current autistic features in adolescents with schizotypal personality disorder
    Michelle L Esterberg
    Emory University Graduate School of Arts and Sciences, Department of Psychology, United States, 1462 Clifton Road, Suite 235, Atlanta, GA 30322, United States
    Schizophr Res 104:265-73. 2008
    ..The findings indicate that past and current autistic signs are more common in adolescents with SPD, but neither current nor childhood autistic features are linked with conversion to psychosis...
  19. pmc Physical manifestations of neurodevelopmental disruption: are minor physical anomalies part of the syndrome of schizophrenia?
    Michael T Compton
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 49 Jesse Hill Jr Drive, SE, Room No 333, Atlanta, GA 30303, USA
    Schizophr Bull 35:425-36. 2009
    ....
  20. doi request reprint Patient-level predictors and clinical correlates of duration of untreated psychosis among hospitalized first-episode patients
    Michael T Compton
    Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, 49 Jesse Hill Jr Drive, SE, Room 333, Atlanta, GA 30303, USA
    J Clin Psychiatry 72:225-32. 2011
    ..This study examined patient-level predictors of DUP and clinical correlates of both DUP and duration of untreated illness (DUI), both of which have been implicated as prognostic indicators...
  21. pmc Early signs, diagnosis and therapeutics of the prodromal phase of schizophrenia and related psychotic disorders
    Molly K Larson
    Emory University, Department of Psychology, Atlanta, GA, USA
    Expert Rev Neurother 10:1347-59. 2010
    ..Findings support further research for the establishment of best-practice standards...
  22. doi request reprint Characteristics of the retrospectively assessed prodromal period in hospitalized patients with first-episode nonaffective psychosis: findings from a socially disadvantaged, low-income, predominantly African American population
    Michael T Compton
    Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, 49 Jesse Hill Jr Drive, SE, Room 333, Atlanta, GA 30303, USA
    J Clin Psychiatry 71:1279-85. 2010
    ..This study describes the prodromal period of 109 hospitalized first-episode patients from an urban, socially disadvantaged, predominantly African American population...
  23. ncbi request reprint Lack of support for the inability to taste phenylthiocarbamide as an endophenotypic marker in patients with schizophrenia and their first-degree relatives
    Michael T Compton
    Emory University School of Medicine, 49 Jesse Hill Jr Drive, S E, Room 333, Atlanta, GA 30303, USA
    Schizophr Res 95:65-9. 2007
    ..Associations between PTC-tasting status and olfactory identification scores also were examined...
  24. pmc Elevated social Internet use and schizotypal personality disorder in adolescents
    Vijay A Mittal
    Emory University, Psychology, Department of Psychology, 235 Dental Building, 1462 Clifton Road, Atlanta, GA 30322, USA
    Schizophr Res 94:50-7. 2007
    ....
  25. ncbi request reprint Observations on parent/family factors that may influence the duration of untreated psychosis among African American first-episode schizophrenia-spectrum patients
    Michael T Compton
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Grady Memorial Hospital, Box 26238, 80 Jesse Hill Jr Drive, S E, Atlanta, GA 30303, USA
    Schizophr Res 68:373-85. 2004
    ..These preliminary observations may serve to generate hypotheses for further research that aims to elucidate the determinants of treatment delays in the early course of schizophrenia, especially among African American populations...
  26. ncbi request reprint The influence of perceived control and locus of control on the cortisol and subjective responses to stress
    Annie M Bollini
    Emory University, 1462 Clifton Road, Suite 235, Atlanta, GA 30322, USA
    Biol Psychol 67:245-60. 2004
    ..The results are discussed in light of their implications for elucidating the determinants of the effects of perceived control on stress...
  27. ncbi request reprint Cortisol responses of healthy volunteers undergoing magnetic resonance imaging
    Kevin D Tessner
    Emory University Psychological Center, Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
    Hum Brain Mapp 27:889-95. 2006
    ..The implications for neuroimaging studies are discussed...
  28. ncbi request reprint Factor structure of the Neurological Evaluation Scale in a predominantly African American sample of patients with schizophrenia, unaffected relatives, and non-psychiatric controls
    Michael T Compton
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 49 Jesse Hill Jr Drive, S E, Atlanta, GA 30303, USA
    Schizophr Res 84:365-77. 2006
    ..This study aimed to identify latent factors of the most widely used scale to measure neurological soft signs, the Neurological Evaluation Scale (NES), in a sample of schizophrenia patients, their relatives, and non-psychiatric controls...
  29. ncbi request reprint Gesture behavior in unmedicated schizotypal adolescents
    Vijay A Mittal
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    J Abnorm Psychol 115:351-8. 2006
    ..The findings are discussed in light of brain regions involved in dysfunction, parallels to schizophrenia, and treatment implications...
  30. ncbi request reprint Associations between olfactory identification and verbal memory in patients with schizophrenia, first-degree relatives, and non-psychiatric controls
    Michael T Compton
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
    Schizophr Res 86:154-66. 2006
    ....
  31. ncbi request reprint The relations among putative biorisk markers in schizotypal adolescents: minor physical anomalies, movement abnormalities, and salivary cortisol
    Vijay A Mittal
    Emory University, Department of Psychology, Atlanta, Georgia 30322, USA
    Biol Psychiatry 61:1179-86. 2007
    ....
  32. doi request reprint Longitudinal progression of movement abnormalities in relation to psychotic symptoms in adolescents at high risk of schizophrenia
    Vijay A Mittal
    Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
    Arch Gen Psychiatry 65:165-71. 2008
    ..To date, there have been no published longitudinal studies examining the progression of movement abnormalities and their relation with symptom progression in at-risk youth...
  33. ncbi request reprint Movement abnormalities and the progression of prodromal symptomatology in adolescents at risk for psychotic disorders
    Vijay A Mittal
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    J Abnorm Psychol 116:260-7. 2007
    ..Within the SPD group, baseline movement abnormalities predicted symptom severity 1 year later. Movement abnormalities represent an early risk indicator that may be predictive of later symptom severity and potentially of psychosis onset...
  34. ncbi request reprint Neurological soft signs and minor physical anomalies in patients with schizophrenia and related disorders, their first-degree biological relatives, and non-psychiatric controls
    Michael T Compton
    Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, 49 Jesse Hill Jr Drive, S E, Room 333, Atlanta, GA 30303, United States
    Schizophr Res 94:64-73. 2007
    ....
  35. ncbi request reprint Facial measurement differences between patients with schizophrenia and non-psychiatric controls
    Michael T Compton
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 101 Woodruff Circle, Suite 4000, Atlanta, Georgia, 30322, United States
    Schizophr Res 93:245-52. 2007
    ..differ from controls in terms of a number of specific facial measurements?, and (2) Does cluster analysis based on these facial measurements reveal distinct facial morphologies that significantly discriminate patients from controls?..
  36. pmc Catechol-O-methyltransferase modulation of cortisol secretion in psychiatrically at-risk and healthy adolescents
    Deborah J Walder
    Department of Psychology, Brooklyn College and the Graduate Center of the City University of New York, New York 11210, USA
    Psychiatr Genet 20:166-70. 2010
    ..In addition, this study examined the relation of COMT genotype with longitudinal changes in cortisol...
  37. ncbi request reprint Plasma hormones and catecholamine metabolites in monozygotic twins discordant for psychosis
    Elaine F Walker
    Emory University, Atlanta, Georgia 30322, USA
    Neuropsychiatry Neuropsychol Behav Neurol 15:10-7. 2002
    ..To examine plasma cortisol, adrencorticotropin hormone, and indicators of catecholamine activity in monozygotic twins discordant for schizophrenia or major affective disorders...
  38. ncbi request reprint Childhood videotaped social and neuromotor precursors of schizophrenia: a prospective investigation
    Jason Schiffman
    Department of Psychology, University of Hawaii at Manoa, Gartley Hall 110, 2430 Campus Road, Honolulu, HI 96822 2216, USA
    Am J Psychiatry 161:2021-7. 2004
    ..The authors examined videotaped behaviors of children who developed schizophrenia as adults and of comparison subjects to disclose possible social and neuromotor deficits foreshadowing later development of schizophrenia...
  39. ncbi request reprint A descriptive study of pathways to care among hospitalized urban African American first-episode schizophrenia-spectrum patients
    Michael T Compton
    Dept of Psychiatry, Emory University School of Medicine, Grady Memorial Hospital, Box 26238, 80 Jesse Hill Jr Drive, S E, Atlanta, GA 30303, USA
    Soc Psychiatry Psychiatr Epidemiol 41:566-73. 2006
    ..The objectives of this study were to examine the pathways to care and number of help contacts prior to hospitalization in first-episode patients, and to ascertain the frequency of contact with primary care providers and police...
  40. ncbi request reprint Neuromotor functioning in adolescents with schizotypal personality disorder: associations with symptoms and neurocognition
    Craig S Neumann
    Department of Psychology, University of North Texas, Denton 76203 1280, USA
    Schizophr Bull 29:285-98. 2003
    ..Differences as well as broad similarities in the pattern of motor findings between the adult and adolescent SPD studies are discussed...
  41. pmc North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia research
    Jean Addington
    Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada
    Schizophr Bull 33:665-72. 2007
    ....
  42. ncbi request reprint Course of general cognitive functioning in high-risk individuals with psychosis outcomes
    Annie M Bollini
    Schizophr Res 79:347-8. 2005
  43. ncbi request reprint Associations between schizotypal features and indicators of neurological and morphological abnormalities
    Annie M Bollini
    Emory University School of Medicine, USA
    Schizophr Res 92:32-40. 2007
    ..Additionally, associations between MPA scores and schizotypy were explored in these two groups...
  44. ncbi request reprint Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factor
    Deborah J Walder
    Psychology Department at Brooklyn College City University of New York, Brooklyn, NY 11210, USA
    Schizophr Res 86:118-22. 2006
    ..Diagnostic group differences were restricted to White/Caucasian males with greater right 2D:4D in SPDs. Findings suggest disruptions in prenatal gonadal hormones in vulnerability for schizophrenia...

Research Grants6

  1. Prediction of Psychosis in Schizotypal Adolescents
    Elaine Walker; Fiscal Year: 2006
    ..In the long-term, the research holds promise for yielding findings that have implications for our conceptualization of the prodromal course of schizophrenia and other psychoses, and for approaches to preventive intervention. ..