Irwin D Waldman

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi request reprint The adrenergic receptor alpha-2A gene (ADRA2A) and neuropsychological executive functions as putative endophenotypes for childhood ADHD
    Irwin D Waldman
    Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
    Cogn Affect Behav Neurosci 6:18-30. 2006
  2. pmc Gene x environment interactions for ADHD: synergistic effect of 5HTTLPR genotype and youth appraisals of inter-parental conflict
    Molly Nikolas
    Department of Psychology, Michigan State University, East Lansing, Michigan, USA
    Behav Brain Funct 6:23. 2010
  3. ncbi request reprint Antisocial behavior and alcoholism: a behavioral genetic perspective on comorbidity
    I D Waldman
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Clin Psychol Rev 20:255-87. 2000
  4. ncbi request reprint A logistic regression based extension of the TDT for continuous and categorical traits
    I D Waldman
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Ann Hum Genet 63:329-40. 1999
  5. ncbi request reprint Gene-environment interactions reexamined: does mother's marital stability interact with the dopamine receptor D2 gene in the etiology of childhood attention-deficit/hyperactivity disorder?
    Irwin D Waldman
    Department of Psychology, Emory University, 532 North Kilgo Circle, Atlanta, GA 30322, USA
    Dev Psychopathol 19:1117-28. 2007
  6. doi request reprint Child and adolescent conduct disorder substantially shares genetic influences with three socioemotional dispositions
    Irwin D Waldman
    Department of Psychology, Emory University, Atlanta, GA30322, USA
    J Abnorm Psychol 120:57-70. 2011
  7. ncbi request reprint The genetics of attention deficit hyperactivity disorder
    Irwin D Waldman
    Emory University, USA
    Clin Psychol Rev 26:396-432. 2006
  8. ncbi request reprint Statistical approaches to complex phenotypes: evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder
    Irwin D Waldman
    Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
    Biol Psychiatry 57:1347-56. 2005
  9. pmc A quasi-experimental analysis of the influence of neighborhood disadvantage on child and adolescent conduct problems
    Jackson A Goodnight
    Department of Psychology, University of Dayton, Dayton, OH 45469 1430, USA
    J Abnorm Psychol 121:95-108. 2012
  10. doi request reprint Evaluating the utility of sluggish cognitive tempo in discriminating among DSM-IV ADHD subtypes
    Kelly M Harrington
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    J Abnorm Child Psychol 38:173-84. 2010

Research Grants

Detail Information

Publications34

  1. ncbi request reprint The adrenergic receptor alpha-2A gene (ADRA2A) and neuropsychological executive functions as putative endophenotypes for childhood ADHD
    Irwin D Waldman
    Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
    Cogn Affect Behav Neurosci 6:18-30. 2006
    ..Implications of the results for evaluating the validity and utility of putative endophenotype measures and for finding candidate gene effects on ADHD are discussed...
  2. pmc Gene x environment interactions for ADHD: synergistic effect of 5HTTLPR genotype and youth appraisals of inter-parental conflict
    Molly Nikolas
    Department of Psychology, Michigan State University, East Lansing, Michigan, USA
    Behav Brain Funct 6:23. 2010
    ....
  3. ncbi request reprint Antisocial behavior and alcoholism: a behavioral genetic perspective on comorbidity
    I D Waldman
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Clin Psychol Rev 20:255-87. 2000
    ..e., genetic and environmental influences) on comorbidity. Although not a panacea and somewhat demanding technically, behavior genetic approaches can shed new light on the comorbidity among disorders...
  4. ncbi request reprint A logistic regression based extension of the TDT for continuous and categorical traits
    I D Waldman
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Ann Hum Genet 63:329-40. 1999
    ..Given its features, we regard the logistic regression extension of the TDT as a flexible new data analytic method with extensive potential applications to problems in medical, psychiatric, and behavioral genetics...
  5. ncbi request reprint Gene-environment interactions reexamined: does mother's marital stability interact with the dopamine receptor D2 gene in the etiology of childhood attention-deficit/hyperactivity disorder?
    Irwin D Waldman
    Department of Psychology, Emory University, 532 North Kilgo Circle, Atlanta, GA 30322, USA
    Dev Psychopathol 19:1117-28. 2007
    ..The present findings highlight the importance of considering both the nexus of putative environmental risk factors and whether their etiology and effects are truly environmental in future Gene x Environment interaction research...
  6. doi request reprint Child and adolescent conduct disorder substantially shares genetic influences with three socioemotional dispositions
    Irwin D Waldman
    Department of Psychology, Emory University, Atlanta, GA30322, USA
    J Abnorm Psychol 120:57-70. 2011
    ....
  7. ncbi request reprint The genetics of attention deficit hyperactivity disorder
    Irwin D Waldman
    Emory University, USA
    Clin Psychol Rev 26:396-432. 2006
    ..We conclude with a consideration of some of the emerging themes that will be important in future studies of the genetics of ADHD...
  8. ncbi request reprint Statistical approaches to complex phenotypes: evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder
    Irwin D Waldman
    Department of Psychology, Emory University, Atlanta, Georgia 30322, USA
    Biol Psychiatry 57:1347-56. 2005
    ..It is demonstrated that both putative endophenotypes show association with the dopamine D4 receptor gene and meet most (but not all) of the criteria proposed for their validity and utility...
  9. pmc A quasi-experimental analysis of the influence of neighborhood disadvantage on child and adolescent conduct problems
    Jackson A Goodnight
    Department of Psychology, University of Dayton, Dayton, OH 45469 1430, USA
    J Abnorm Psychol 121:95-108. 2012
    ..These findings are consistent with the hypothesis that ND has influence on conduct problems...
  10. doi request reprint Evaluating the utility of sluggish cognitive tempo in discriminating among DSM-IV ADHD subtypes
    Kelly M Harrington
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    J Abnorm Child Psychol 38:173-84. 2010
    ....
  11. doi request reprint Relations between multi-informant assessments of ADHD symptoms, DAT1, and DRD4
    Ian R Gizer
    Department of Psychology, Emory University, 532 N Kilgo Circle, Atlanta, GA 30322, USA
    J Abnorm Psychol 117:869-80. 2008
    ..e., the and, or, and averaging rules). The implications of these results for future molecular genetic studies of ADHD are discussed...
  12. pmc Population density and youth antisocial behavior
    K Paige Harden
    Department of Psychology, University of Virginia, Charlottesville, USA
    J Child Psychol Psychiatry 50:999-1008. 2009
    ..Rather, the association between population density and delinquency appears to be due to unmeasured selection variables that differ between families who live in more or less densely populated counties...
  13. ncbi request reprint Genetic and environmental influences on antisocial behavior: a meta-analysis of twin and adoption studies
    Soo Hyun Rhee
    Department of Psychology, Emory University, USA
    Psychol Bull 128:490-529. 2002
    ....
  14. ncbi request reprint Gene-environment interactions in attention-deficit/hyperactivity disorder
    Courtney A Ficks
    Emory University, 317 Psychology Building, 532 Kilgo Circle, Atlanta, GA 30322, USA
    Curr Psychiatry Rep 11:387-92. 2009
    ..We discuss these findings and the future directions and limitations of current gene-environment research...
  15. ncbi request reprint Is depression best viewed as a continuum or discrete category? A taxometric analysis of childhood and adolescent depression in a population-based sample
    Benjamin L Hankin
    Department of Psychology, University of Illinois at Chicago, Chicago, IL, USA
    J Abnorm Psychol 114:96-110. 2005
    ..e., boys vs. girls and younger vs. older youth)...
  16. ncbi request reprint Sex differences in the etiology of psychopathic traits in youth
    Courtney A Ficks
    Department of Psychology, Emory University
    J Abnorm Psychol 123:406-11. 2014
    ..No qualitative sex differences were found in the influences underlying any of the 3 trait dimensions, suggesting that the same genes and environments contribute to these psychopathic traits in males and females...
  17. doi request reprint Fearless dominance and the U.S. presidency: implications of psychopathic personality traits for successful and unsuccessful political leadership
    Scott O Lilienfeld
    Department of Psychology, Emory University, Atlanta, GA, USA
    J Pers Soc Psychol 103:489-505. 2012
    ....
  18. pmc Annual research review: phenotypic and causal structure of conduct disorder in the broader context of prevalent forms of psychopathology
    Benjamin B Lahey
    Departments of Health Studies and Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA
    J Child Psychol Psychiatry 53:536-57. 2012
    ..We posit that any prevalent form of psychopathology, including CD, can be best understood if it is studied in the context of other correlated forms of child and adolescent psychopathology using formal models to guide inquiry...
  19. ncbi request reprint Improved association analyses of disease subtypes in case-parent triads
    Michael P Epstein
    Department of Human Genetics, Emory University, Atlanta, Georgia 30322, USA
    Genet Epidemiol 30:209-19. 2006
    ....
  20. ncbi request reprint Sex differences in the causes of self-reported adolescent delinquency
    Carol A Van Hulle
    Department of Health Studies, University of Chicago, Chicago, IL 60637, USA
    J Abnorm Psychol 116:236-48. 2007
    ..Similarly, a test of the polygenic multiple threshold model suggested that girls require greater causal liability for the expression of delinquency than boys...
  21. ncbi request reprint The structure of child and adolescent psychopathology: generating new hypotheses
    Benjamin B Lahey
    Department of Psychiatry, University of Chicago, Chicago, IL 60637, USA
    J Abnorm Psychol 113:358-85. 2004
    ....
  22. ncbi request reprint Dopamine transporter genotype and methylphenidate dose response in children with ADHD
    Mark A Stein
    Department of Psychiatry, The University of Chicago, Chicago, IL 60637, USA
    Neuropsychopharmacology 30:1374-82. 2005
    ..Further research is needed to determine the mechanisms related to poor response in patients with the 9/9-repeat genotype, and to determine if this group responds differentially to alternative treatments...
  23. ncbi request reprint Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD?
    Alysa E Doyle
    Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Child Psychol Psychiatry 46:774-803. 2005
    ..Thus far, potential endophenotypes for ADHD have not been systematically studied...
  24. pmc Smoking during pregnancy and offspring externalizing problems: an exploration of genetic and environmental confounds
    Brian M D'Onofrio
    Indiana University, Bloomington, IN 47405, USA
    Dev Psychopathol 20:139-64. 2008
    ..That is, the current analyses imply that important unidentified environmental factors account for the association between SDP and offspring externalizing problems, not teratogenic effects of SDP...
  25. doi request reprint Functional gene variation in the human norepinephrine transporter: association with attention deficit hyperactivity disorder
    Chun Hyung Kim
    Molecular Neurobiology Laboratory, McLean Hospital, Harvard Medical School, 115 Mill St, Belmont, MA 02478, USA
    Ann N Y Acad Sci 1129:256-60. 2008
    ..Moreover, we observed a significant association of the -3081(T) variant with ADHD. Altered transcription of SLC6A2 may therefore represent a novel risk factor for the development of ADHD...
  26. pmc A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder
    Chun Hyung Kim
    Molecular Neurobiology, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA
    Proc Natl Acad Sci U S A 103:19164-9. 2006
    ....
  27. ncbi request reprint Testing structural models of DSM-IV symptoms of common forms of child and adolescent psychopathology
    Benjamin B Lahey
    Department of Health Studies MC 2007, University of Chicago, 5811 South Maryland Avenue, Chicago, IL 60637, USA
    J Abnorm Child Psychol 36:187-206. 2008
    ....
  28. ncbi request reprint Normal variation and abnormality: an empirical study of the liability distributions underlying depression and delinquency
    Edwin J C G van den Oord
    Department of Psychiatry, Medical College of Virginia of Virginia Commonwealth University, Richmond 23298 0126, USA
    J Child Psychol Psychiatry 44:180-92. 2003
    ..This invites an interpretation of their forming an abnormal group, one that may be qualitatively distinct...
  29. ncbi request reprint A dose-response study of OROS methylphenidate in children with attention-deficit/hyperactivity disorder
    Mark A Stein
    Department of Psychiatry, University of Chicago, Chicago, Illinois 60637, USA
    Pediatrics 112:e404. 2003
    ..This study was conducted to examine dosage effects on ADHD symptoms and stimulant side effects and to explore potential moderating effects of ADHD subtype...
  30. ncbi request reprint Etiology of sex differences in the prevalence of ADHD: an examination of inattention and hyperactivity-impulsivity
    Soo Hyun Rhee
    Department of Psychology and Institute for Behavioral Genetics, University of Colorado, Colorado 80309, USA
    Am J Med Genet B Neuropsychiatr Genet 127:60-4. 2004
    ..This evidence for the PMT model and against the CV model was found for both inattention and hyperactivity-impulsivity, but became weaker for hyperactivity-impulsivity as symptom severity increased...
  31. ncbi request reprint Testing descriptive hypotheses regarding sex differences in the development of conduct problems and delinquency
    Benjamin B Lahey
    Department of Health Studies, University of Chicago, IL 60637, USA
    J Abnorm Child Psychol 34:737-55. 2006
    ..Although more males followed a childhood-onset trajectory, there were few sex differences in the early childhood risk correlates of either delinquency trajectory...
  32. ncbi request reprint Causal inferences regarding prenatal alcohol exposure and childhood externalizing problems
    Brian M D'Onofrio
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA
    Arch Gen Psychiatry 64:1296-304. 2007
    ..Existing research on the neurobehavioral consequences of prenatal alcohol exposure (PAE) has not adequately accounted for genetic and environmental confounds...
  33. pmc Specification, testing, and interpretation of gene-by-measured-environment interaction models in the presence of gene-environment correlation
    Paul J Rathouz
    Department of Health Studies, University of Chicago, 5841 S Maryland Ave, MC 2007, Chicago, IL 60637, USA
    Behav Genet 38:301-15. 2008
    ..We propose a statistical method for deriving and interpreting variance decompositions that are true to the fitted model...
  34. ncbi request reprint Investigation of parent-of-origin effects in ADHD candidate genes
    Jang Woo Kim
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Med Genet B Neuropsychiatr Genet 144:776-80. 2007
    ..Thus, we conclude that a substantial parent-of-origin effect is unlikely for these leading ADHD candidate genes...

Research Grants1

  1. MOLECULAR GENETICS OF CHILDHOOD DISRUPTIVE DISORDERS
    Irwin Waldman; Fiscal Year: 2004
    ..The proposed study will increase substantially our understanding of specific genetic influences on the childhood disruptive disorders. ..