Research Topics
| J Bruce SundstromSummaryAffiliation: Emory University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Is peripartum cardiomyopathy an organ-specific autoimmune disease?J Bruce Sundstrom
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Autoimmun Rev 1:73-7. 2002..g. expression of PD-L1 on cardiac tissues and the role of regulatory T cells, may help to elucidate the autoimmune mechanisms of PPCM...
Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cellsJ B Sundstrom
Department of Pathology and Laboratory Medicine, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30323, USA
J Virol 75:6070-85. 2001..These results reveal a possible mechanism by which hantavirus infection and a TH1 immune response can cooperate to synergistically enhance chemokine expression by HMVEC-Ls and trigger immune-mediated increases in vascular permeability...- Effects of norepinephrine, HIV type 1 infection, and leukocyte interactions with endothelial cells on the expression of matrix metalloproteinasesJ B Sundstrom
Department of Laboratory Medicine, Winship Cancer Institute, Room B4337, Emory University School of Medicine, Atlanta, GA 30322, USA
AIDS Res Hum Retroviruses 17:1605-14. 2001.... - Human tissue mast cells are an inducible reservoir of persistent HIV infectionJ Bruce Sundstrom
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Blood 109:5293-300. 2007..These data provide the first in vivo evidence that tissue MCs, developed from infected circulating prMCs, comprise a long-lived inducible reservoir of persistent HIV in infected persons during HAART... - Signaling through Toll-like receptors triggers HIV-1 replication in latently infected mast cellsJ Bruce Sundstrom
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
J Immunol 172:4391-401. 2004..Taken together, these results indicate that mast cells may serve both as a viral reservoir and as a model for studying mechanisms of postintegration latency in HIV infection... - Magnetic resonance imaging of activated proliferating rhesus macaque T cells labeled with superparamagnetic monocrystalline iron oxide nanoparticlesJ Bruce Sundstrom
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Woodruff Memorial Building, Room 2335A, 1639 Pierce Drive, Atlanta, GA, USA
J Acquir Immune Defic Syndr 35:9-21. 2004..These results indicate that intracellular labeling with MION can be a useful technique for noninvasively monitoring trafficking patterns of adoptively transferred leukocyte subsets in real-time by MRI in nonhuman primate models of AIDS... - Norepinephrine enhances adhesion of HIV-1-infected leukocytes to cardiac microvascular endothelial cellsJ B Sundstrom
Department of Pathology, Emory University, Atlanta, Georgia 30322, USA
Exp Biol Med (Maywood) 228:730-40. 2003..These data suggest a model in which NE primes HIV-1-infected leukocytes for enhanced adhesion and localization in HMVEC-C where they can initiate and participate in vascular injury associated with AIDS-related cardiomyopathy... - Fetal cord blood mononuclear cells that are collected at term from HIV-1 infected women harbor transcriptionally active integrated proviral DNAJane E Ellis
Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA
Am J Obstet Gynecol 197:371.e1-6. 2007.... - IgE-FcepsilonRI interactions determine HIV coreceptor usage and susceptibility to infection during ontogeny of mast cellsJ Bruce Sundstrom
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
J Immunol 182:6401-9. 2009.... - Autoimmune mechanisms as the basis for human peripartum cardiomyopathyAftab A Ansari
Department of Pathology and Laboratory Medicine, Room 4107B Winship Cancer Institute, Emory University School of Medicine, 1365 B Clifton Rd, Atlanta, GA 30322, USA
Clin Rev Allergy Immunol 23:301-24. 2002..A working model for the pathogenesis of this disease is also described herein... - Below the belt: new insights into potential complications of HIV-1/schistosome coinfectionsW Evan Secor
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
Curr Opin Infect Dis 20:519-23. 2007..In this review, the 'gut wrenching' consequences of schistosome infection on HIV disease progression that may ensue during coinfection are considered... - IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaquesF Villinger
Department of Pathology and Laboratory Medicine, Emory University, Woodruff Memorial Building 2339, 1639 Pierce Drive, Atlanta, GA 30322, USA
Vaccine 22:3510-21. 2004..Following booster immunization, however, only IL-15 appeared able to enhance CD8 T cell responses while IL-2 or IL2/IL-15 administration were less effective... - Administration of recombinant rhesus interleukin-12 during acute simian immunodeficiency virus (SIV) infection leads to decreased viral loads associated with prolonged survival in SIVmac251-infected rhesus macaquesA A Ansari
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Virol 76:1731-43. 2002..This is the first study to demonstrate the capacity of IL-12 to significantly protect macaques from SIV-induced disease, and it provides a useful model to more precisely identify correlates of virus-specific disease-protective responses... - Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infectionF Villinger
Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia 30322, USA
J Infect Dis 179:S188-91. 1999..Taken together, these results suggest that a high degree of immune activation accompanies and potentially contributes to a fatal outcome in EHF patients... - Unusual presentation of anaplastic large cell lymphoma with clinical course mimicking fever of unknown origin and sepsis: autopsy study of five casesMarina B Mosunjac
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Room CG 42, Atlanta, GA 30303, USA
Croat Med J 49:660-8. 2008..To describe a subset of cases with the unusual clinical and histomorphological presentation of anaplastic large cell lymphoma (ALCL) mimicking fever of unknown origin (FUO) and sepsis... - Magnitude of alloresponses to MHC class I/II expressing human cardiac myocytes is limited by their intrinsic ability to process and present antigenic peptidesJ Bruce Sundstrom
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Clin Dev Immunol 10:213-26. 2003..These results suggest that weak allogenicity of cardiac myocytes may be governed by their limited expression of MHC genes and gene products critical for antigen processing and presentation... 
Combined pathological effects of cocaine abuse and HIV infection on the cardiovascular system: an autopsy study of 187 cases from the Fulton County Medical Examiner's officeMario I Mosunjac
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
Am J Forensic Med Pathol 29:9-13. 2008..5%, 17.4%, and 17.4% vs. 6.5%, 3.3%, and 0% in CONT group) may indicate possible combined and/or cumulative effects of HIV and cocaine on cardiovascular pathology...- Peripartum cardiomyopathy: a selenium disconnection and an autoimmune connectionJames D Fett
Department of Adult Medicine, Hospital Albert Schweitzer, Deschapelles, Haiti
Int J Cardiol 86:311-6. 2002..This report details results of initial studies to test the hypothesis that plasma levels of Se and/or other micronutrients may be related to PPCM risk in this population...