J Bruce Sundstrom

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi request reprint Is peripartum cardiomyopathy an organ-specific autoimmune disease?
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Autoimmun Rev 1:73-7. 2002
  2. pmc Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells
    J B Sundstrom
    Department of Pathology and Laboratory Medicine, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30323, USA
    J Virol 75:6070-85. 2001
  3. ncbi request reprint Effects of norepinephrine, HIV type 1 infection, and leukocyte interactions with endothelial cells on the expression of matrix metalloproteinases
    J B Sundstrom
    Department of Laboratory Medicine, Winship Cancer Institute, Room B4337, Emory University School of Medicine, Atlanta, GA 30322, USA
    AIDS Res Hum Retroviruses 17:1605-14. 2001
  4. pmc Human tissue mast cells are an inducible reservoir of persistent HIV infection
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Blood 109:5293-300. 2007
  5. ncbi request reprint Signaling through Toll-like receptors triggers HIV-1 replication in latently infected mast cells
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Immunol 172:4391-401. 2004
  6. ncbi request reprint Magnetic resonance imaging of activated proliferating rhesus macaque T cells labeled with superparamagnetic monocrystalline iron oxide nanoparticles
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Woodruff Memorial Building, Room 2335A, 1639 Pierce Drive, Atlanta, GA, USA
    J Acquir Immune Defic Syndr 35:9-21. 2004
  7. ncbi request reprint Norepinephrine enhances adhesion of HIV-1-infected leukocytes to cardiac microvascular endothelial cells
    J B Sundstrom
    Department of Pathology, Emory University, Atlanta, Georgia 30322, USA
    Exp Biol Med (Maywood) 228:730-40. 2003
  8. pmc Fetal cord blood mononuclear cells that are collected at term from HIV-1 infected women harbor transcriptionally active integrated proviral DNA
    Jane E Ellis
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA
    Am J Obstet Gynecol 197:371.e1-6. 2007
  9. pmc IgE-FcepsilonRI interactions determine HIV coreceptor usage and susceptibility to infection during ontogeny of mast cells
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Immunol 182:6401-9. 2009
  10. ncbi request reprint Autoimmune mechanisms as the basis for human peripartum cardiomyopathy
    Aftab A Ansari
    Department of Pathology and Laboratory Medicine, Room 4107B Winship Cancer Institute, Emory University School of Medicine, 1365 B Clifton Rd, Atlanta, GA 30322, USA
    Clin Rev Allergy Immunol 23:301-24. 2002

Detail Information

Publications18

  1. ncbi request reprint Is peripartum cardiomyopathy an organ-specific autoimmune disease?
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Autoimmun Rev 1:73-7. 2002
    ..g. expression of PD-L1 on cardiac tissues and the role of regulatory T cells, may help to elucidate the autoimmune mechanisms of PPCM...
  2. pmc Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells
    J B Sundstrom
    Department of Pathology and Laboratory Medicine, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30323, USA
    J Virol 75:6070-85. 2001
    ..These results reveal a possible mechanism by which hantavirus infection and a TH1 immune response can cooperate to synergistically enhance chemokine expression by HMVEC-Ls and trigger immune-mediated increases in vascular permeability...
  3. ncbi request reprint Effects of norepinephrine, HIV type 1 infection, and leukocyte interactions with endothelial cells on the expression of matrix metalloproteinases
    J B Sundstrom
    Department of Laboratory Medicine, Winship Cancer Institute, Room B4337, Emory University School of Medicine, Atlanta, GA 30322, USA
    AIDS Res Hum Retroviruses 17:1605-14. 2001
    ....
  4. pmc Human tissue mast cells are an inducible reservoir of persistent HIV infection
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Blood 109:5293-300. 2007
    ..These data provide the first in vivo evidence that tissue MCs, developed from infected circulating prMCs, comprise a long-lived inducible reservoir of persistent HIV in infected persons during HAART...
  5. ncbi request reprint Signaling through Toll-like receptors triggers HIV-1 replication in latently infected mast cells
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Immunol 172:4391-401. 2004
    ..Taken together, these results indicate that mast cells may serve both as a viral reservoir and as a model for studying mechanisms of postintegration latency in HIV infection...
  6. ncbi request reprint Magnetic resonance imaging of activated proliferating rhesus macaque T cells labeled with superparamagnetic monocrystalline iron oxide nanoparticles
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Woodruff Memorial Building, Room 2335A, 1639 Pierce Drive, Atlanta, GA, USA
    J Acquir Immune Defic Syndr 35:9-21. 2004
    ..These results indicate that intracellular labeling with MION can be a useful technique for noninvasively monitoring trafficking patterns of adoptively transferred leukocyte subsets in real-time by MRI in nonhuman primate models of AIDS...
  7. ncbi request reprint Norepinephrine enhances adhesion of HIV-1-infected leukocytes to cardiac microvascular endothelial cells
    J B Sundstrom
    Department of Pathology, Emory University, Atlanta, Georgia 30322, USA
    Exp Biol Med (Maywood) 228:730-40. 2003
    ..These data suggest a model in which NE primes HIV-1-infected leukocytes for enhanced adhesion and localization in HMVEC-C where they can initiate and participate in vascular injury associated with AIDS-related cardiomyopathy...
  8. pmc Fetal cord blood mononuclear cells that are collected at term from HIV-1 infected women harbor transcriptionally active integrated proviral DNA
    Jane E Ellis
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA
    Am J Obstet Gynecol 197:371.e1-6. 2007
    ....
  9. pmc IgE-FcepsilonRI interactions determine HIV coreceptor usage and susceptibility to infection during ontogeny of mast cells
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Immunol 182:6401-9. 2009
    ....
  10. ncbi request reprint Autoimmune mechanisms as the basis for human peripartum cardiomyopathy
    Aftab A Ansari
    Department of Pathology and Laboratory Medicine, Room 4107B Winship Cancer Institute, Emory University School of Medicine, 1365 B Clifton Rd, Atlanta, GA 30322, USA
    Clin Rev Allergy Immunol 23:301-24. 2002
    ..A working model for the pathogenesis of this disease is also described herein...
  11. ncbi request reprint Below the belt: new insights into potential complications of HIV-1/schistosome coinfections
    W Evan Secor
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Curr Opin Infect Dis 20:519-23. 2007
    ..In this review, the 'gut wrenching' consequences of schistosome infection on HIV disease progression that may ensue during coinfection are considered...
  12. ncbi request reprint IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques
    F Villinger
    Department of Pathology and Laboratory Medicine, Emory University, Woodruff Memorial Building 2339, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Vaccine 22:3510-21. 2004
    ..Following booster immunization, however, only IL-15 appeared able to enhance CD8 T cell responses while IL-2 or IL2/IL-15 administration were less effective...
  13. pmc Administration of recombinant rhesus interleukin-12 during acute simian immunodeficiency virus (SIV) infection leads to decreased viral loads associated with prolonged survival in SIVmac251-infected rhesus macaques
    A A Ansari
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Virol 76:1731-43. 2002
    ..This is the first study to demonstrate the capacity of IL-12 to significantly protect macaques from SIV-induced disease, and it provides a useful model to more precisely identify correlates of virus-specific disease-protective responses...
  14. ncbi request reprint Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection
    F Villinger
    Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia 30322, USA
    J Infect Dis 179:S188-91. 1999
    ..Taken together, these results suggest that a high degree of immune activation accompanies and potentially contributes to a fatal outcome in EHF patients...
  15. pmc Unusual presentation of anaplastic large cell lymphoma with clinical course mimicking fever of unknown origin and sepsis: autopsy study of five cases
    Marina B Mosunjac
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Room CG 42, Atlanta, GA 30303, USA
    Croat Med J 49:660-8. 2008
    ..To describe a subset of cases with the unusual clinical and histomorphological presentation of anaplastic large cell lymphoma (ALCL) mimicking fever of unknown origin (FUO) and sepsis...
  16. pmc Magnitude of alloresponses to MHC class I/II expressing human cardiac myocytes is limited by their intrinsic ability to process and present antigenic peptides
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Clin Dev Immunol 10:213-26. 2003
    ..These results suggest that weak allogenicity of cardiac myocytes may be governed by their limited expression of MHC genes and gene products critical for antigen processing and presentation...
  17. doi request reprint Combined pathological effects of cocaine abuse and HIV infection on the cardiovascular system: an autopsy study of 187 cases from the Fulton County Medical Examiner's office
    Mario I Mosunjac
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
    Am J Forensic Med Pathol 29:9-13. 2008
    ..5%, 17.4%, and 17.4% vs. 6.5%, 3.3%, and 0% in CONT group) may indicate possible combined and/or cumulative effects of HIV and cocaine on cardiovascular pathology...
  18. ncbi request reprint Peripartum cardiomyopathy: a selenium disconnection and an autoimmune connection
    James D Fett
    Department of Adult Medicine, Hospital Albert Schweitzer, Deschapelles, Haiti
    Int J Cardiol 86:311-6. 2002
    ..This report details results of initial studies to test the hypothesis that plasma levels of Se and/or other micronutrients may be related to PPCM risk in this population...