Research Topics
Species | Kyle SteenlandSummaryAffiliation: Emory University Country: USA Publications
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Publications
Mortality analyses in a cohort of 18 235 ethylene oxide exposed workers: follow up extended from 1987 to 1998K Steenland
Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Occup Environ Med 61:2-7. 2004..To extend mortality follow up from 1987 to 1998 for cohort of 18 235 men and women exposed to ethylene oxide...
Monte Carlo sensitivity analysis and Bayesian analysis of smoking as an unmeasured confounder in a study of silica and lung cancerKyle Steenland
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Am J Epidemiol 160:384-92. 2004..15, 1.78). Bayesian results were similar (95% posterior limits: 1.13, 1.84). The authors believe that these types of analyses, which make explicit and quantify sources of uncertainty, should be more widely adopted by epidemiologists...
Dioxin revisited: developments since the 1997 IARC classification of dioxin as a human carcinogenKyle Steenland
Rollins School of Public Health, Emory University, Atlanta, Georgia 30306, USA
Environ Health Perspect 112:1265-8. 2004..There are also new data regarding how the AhR functions in mediating the carcinogenic response to TCDD. The new evidence generally supports the 1997 IARC classification...
Analyses of diagnostic patterns at 30 Alzheimer's disease centers in the USKyle Steenland
Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Neuroepidemiology 35:19-27. 2010..The US Alzheimer's Disease Centers (ADCs) (n = 30) recently created a uniform data set. We sought to determine which variables were most important in making a diagnosis, and how these differed across ADCs...
Prostate cancer incidence and survival in relation to education (United States)Kyle Steenland
Rollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA 30322, USA
Cancer Causes Control 15:939-45. 2004..There are few data on prostate cancer incidence and survival in relation to socioeconomic status in the 1990s, after the introduction of prostate specific Antigen (PSA) testing...
One agent, many diseases: exposure-response data and comparative risks of different outcomes following silica exposureKyle Steenland
Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA
Am J Ind Med 48:16-23. 2005..Silica has, therefore, joined a handful of other toxic exposures such as tobacco smoke, dioxin, and asbestos which cause multiple serious diseases...
Silica: déjà vu all over again?K Steenland
Rollins School of Public Health, Emory University, Atlanta, GA, USA
Occup Environ Med 62:430-2. 2005
Association of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) with uric acid among adults with elevated community exposure to PFOAKyle Steenland
Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Environ Health Perspect 118:229-33. 2010..PFOA has been associated with elevated uric acid in two studies of chemical workers. Uric acid is a risk factor for hypertension and possibly other cardiovascular outcomes...
Association of perfluorooctanoic acid and perfluorooctane sulfonate with serum lipids among adults living near a chemical plantKyle Steenland
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
Am J Epidemiol 170:1268-78. 2009..Because these data are cross-sectional, causal inference is limited. Nonetheless, the associations between these compounds and lipids raise concerns, given their common presence in the general population...
Predictors of PFOA levels in a community surrounding a chemical plantKyle Steenland
Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Environ Health Perspect 117:1083-8. 2009..S. Environmental Protection Agency. It does not exist in nature but has been used widely since World War II. It is present in the serum of most Americans at about 4-5 ng/mL, although the routes of exposure remain unknown...
Recent trends in Alzheimer disease mortality in the United States, 1999 to 2004Kyle Steenland
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA
Alzheimer Dis Assoc Disord 23:165-70. 2009..AD reporting on death certificates is known to be poor. This is the first analysis of recent trends in AD mortality since the advent of ICD-10...
Polychlorinated biphenyls and neurodegenerative disease mortality in an occupational cohortKyle Steenland
Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, Georgia 30322, USA
Epidemiology 17:8-13. 2006..PCBs decrease dopamine levels in rats and monkeys. Loss of dopamine is the hallmark of Parkinson disease, a neurodegenerative disease. There are no epidemiologic studies of PCBs and neurodegenerative disease...
Development of a rapid screening instrument for mild cognitive impairment and undiagnosed dementiaN Kyle Steenland
Department of Environmental and Occupational Health, School of Public Health, Emory University, Atlanta, GA 30322, USA
J Alzheimers Dis 15:419-27. 2008....
All-cause and cause-specific mortality by socioeconomic status among employed persons in 27 US states, 1984-1997Kyle Steenland
Department of Environmental and Occupational Health, Rollins School of Public Health, 1518 Clifton Avenue, Atlanta, GA 30322, USA
Am J Public Health 94:1037-42. 2004..We investigated mortality differences according to socioeconomic status (SES) for employed persons in 27 states during 1984-1997...
Factors affecting survival of patients with neurodegenerative diseaseKyle Steenland
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Neuroepidemiology 35:28-35. 2010..Survival varies widely among different neurodegenerative diseases. Data on the role of the Mini Mental State Examination (MMSE) and apolipoprotein E (APOE) in survival are sparse except for Alzheimer's disease (AD)...
Mortality patterns following downsizing at Pan American World AirwaysKyle Steenland
Department of Occupational and Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Am J Epidemiol 167:1-6. 2008..69 and 0.64, respectively). These data do not indicate that mortality among those who left involuntarily was higher than for those who left voluntarily. Both groups showed a strong healthy worker effect...
Deaths due to injuries among employed adults: the effects of socioeconomic classKyle Steenland
National Institute for Occupational Safety and Health NIOSH, Atlanta, GA, USA
Epidemiology 14:74-9. 2003..These deaths are of particular interest because they are potentially preventable and they represent the second leading cause of years of life lost under age 75...
Silicosis and end-stage renal diseaseKyle Steenland
National Institute for Occupational Safety and Health NIOSH, Cincinnati, Ohio, USA
Scand J Work Environ Health 28:439-42. 2002..The objective of this study was to determine the incidence of renal disease among workers with silicosis...
Dying for work: The magnitude of US mortality from selected causes of death associated with occupationKyle Steenland
National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA
Am J Ind Med 43:461-82. 2003..Deaths due to occupational disease and injury place a heavy burden on society in terms of economic costs and human suffering...
An overview of methods for calculating the burden of disease due to specific risk factorsKyle Steenland
Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA
Epidemiology 17:512-9. 2006....
Quality of life among men with prostate cancer in rural GeorgiaK Steenland
Emory University Rollins School of Public Health, Atlanta, GA 30322, USA
Urology 77:927-33. 2011..To perform a population-based study on the quality of life (QOL) after prostate cancer treatment in a rural and disadvantaged population, because these have been sparse...
Ethylene oxide and breast cancer incidence in a cohort study of 7576 women (United States)Kyle Steenland
National Institute for Occupational Safety and Health NIOSH, Cincinnati, Ohio 30322, USA
Cancer Causes Control 14:531-9. 2003..ETO causes mammary tumors in mice, and has been associated with breast cancer incidence in one small epidemiologic study...
Epidemiology and drinking water: are we running dry?Kyle Steenland
Department of Environment and Occupational Health at Emory University, Atlanta, GA 30322, USA
Epidemiology 14:635-6. 2003
Risk estimation with epidemiologic data when response attenuates at high-exposure levelsKyle Steenland
Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Environ Health Perspect 119:831-7. 2011..Conversely, a model of untransformed (linear) exposure may underestimate risks attributable to exposures in the low-dose region...
Ten-year update on mortality among mild-steel weldersKyle Steenland
National Institute for Occupational Safety and Health, Cincinnati, Ohio, 45226, USA
Scand J Work Environ Health 28:163-7. 2002..This study is an update on the lung cancer risk of mild-steel welders with no asbestos exposure using a cohort of nonwelders for comparison...
Accumulation and clearance of perfluorooctanoic acid (PFOA) in current and former residents of an exposed communityRyan Seals
Department of Environmental and Occupational Health, Emory University, Atlanta, Georgia, USA
Environ Health Perspect 119:119-24. 2011..Perfluorooctanoic acid (PFOA) is a perfluoroalkyl acid found in > 99% of Americans. Its health effects are unknown. Prior estimates of serum half-life range from 2.3 to 3.8 years...
Cohort mortality study of workers exposed to perfluorooctanoic acidKyle Steenland
Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
Am J Epidemiol 176:909-17. 2012..These results were limited by small numbers and restriction to mortality data, which are of limited relevance for several nonfatal outcomes of a priori interest...
Update of the NIOSH life table analysis system: a person-years analysis program for the windows computing environmentMary K Schubauer-Berigan
Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Am J Ind Med 54:915-24. 2011..Users may export stratified data for Poisson regression modeling. CONCLUSIONS: LTAS.NET incorporates improvements that will facilitate more complex person-years analysis of occupational cohort data...
Use of complementary and alternative medicine among men with prostate cancer in a rural settingSusan Butler
Department of Behavioral Sciences and Health Education, Emory University Rollins School of Public Health, 1518 Clifton Road, Atlanta, GA 30322, USA
J Community Health 36:1004-10. 2011..In line with national patterns, younger and more educated rural patients were significantly more likely to have ever used CAM and to use it after treatment...
The contribution of occupational risks to the global burden of disease: summary and next stepsMarilyn Fingerhut
National Institute for Occupational Safety and Health, Room 715H, Humphrey Building, 200 Independence Avenue SW, Washington, DC 20201, USA
Med Lav 97:313-21. 2006..This article summarizes findings of the WHO CRA project, presents the estimates of the International Labor Organization (ILO) for total deaths due to workplace risks, and calls for action...
Individual- and area-level socioeconomic status variables as predictors of mortality in a cohort of 179,383 personsKyle Steenland
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Am J Epidemiol 159:1047-56. 2004..Multivariate models that consider socioeconomic status as a potential confounder may not need to consider area-level socioeconomic status if data are available on individual-level education...
The effect of race and rural residence on prostate cancer treatment choice among men in GeorgiaKyle Steenland
Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Urology 77:581-7. 2011..To analyze differences for prostate cancer by race and in rural areas...
Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA)Kyle Steenland
Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
Environ Health Perspect 118:1100-8. 2010..CONCLUSIONS: Epidemiologic evidence remains limited, and to date data are insufficient to draw firm conclusions regarding the role of PFOA for any of the diseases of concern...
Time-related aspects of the healthy worker survivor effectDavid Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Ann Epidemiol 14:633-9. 2004..We use simulations and an empirical example to demonstrate that time-since-termination can be a confounding factor in analyses of occupational-exposure-mortality associations...
Dioxin: exposure-response analyses and risk assessmentKyle Steenland
Emory University School of Public Health, Atlanta, Georgia, USA
Ind Health 41:175-80. 2003..1 and 13.0%. Our results agree broadly with results from a German cohort, which is the only other cohort for which a quantitative risk assessment has been conducted...
Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's diseaseAllan Levey
Department of Neurology and Alzheimer s Disease Center, Emory University School of Medicine, Atlanta, GA 30322, USA
Clin Ther 28:991-1001. 2006..Ongoing research is focusing on the identification of those individuals with mild cognitive impairment (MCI) who are most likely to convert to AD. Of the MCI subtypes, patients with amnestic MCI (a-MCI) are at greatest risk...
Attenuation of exposure-response curves in occupational cohort studies at high exposure levelsLeslie Stayner
Risk Evaluation Branch, Education and Information Division, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, United States
Scand J Work Environ Health 29:317-24. 2003....
All-cause and cause-specific death rates by educational status for two million people in two American Cancer Society cohorts, 1959-1996Kyle Steenland
National Institute for Occupational Safety and Health, Cincinnati, OH 45226 1998, USA
Am J Epidemiol 156:11-21. 2002..Temporal trends showed increasing mortality differences by education for coronary heart disease, diabetes, and lung cancer for women...
Caution in drawing conclusions from PBPK models based on sparse human dataKyle Steenland
Risk Anal 27:7-8; author reply 9-10. 2007
Development of quantitative exposure data for a pooled exposure-response analysis of 10 silica cohortsKyle Steenland
Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, Lyon, France
Am J Ind Med 42:73-86. 2002..The difficulties encountered in deriving common exposure estimates across cohorts are discussed...
The global burden of disease due to occupational carcinogensTimothy Driscoll
ELMATOM Pty Ltd, Sydney, Australia
Am J Ind Med 48:419-31. 2005..Cases reported in the year 2000 that resulted from relevant past and current exposures are assessed...
Lung cancer risk and workplace exposure to environmental tobacco smokeLeslie Stayner
School of Public Health, Division of Epidemiology and Biostatistics, University of Illinois, Chicago, IL 60612, USA
Am J Public Health 97:545-51. 2007..We sought to quantitatively evaluate the association between work-place environmental tobacco smoke exposure and lung cancer...
The global burden of selected occupational diseases and injury risks: Methodology and summaryDeborah Imel Nelson
Protection of the Human Environment, World Health Organization, Geneva, Switzerland
Am J Ind Med 48:400-18. 2005..To better advise policy makers, we assessed the global burden of disease and injury due to selected occupational hazards. This article presents an overview, and describes the methodology employed in the companion studies...
Review of estimates of the global burden of injury and illness due to occupational exposuresTimothy Driscoll
School of Public Health, University of Sydney, New South Wales, Australia
Am J Ind Med 48:491-502. 2005..Over the last decade, there have been several attempts to estimate the global burden of ill health due to work activity. The most recent of these is the Comparative Risk Assessment (CRA) project of the World Health Organization...
Higher serum uric acid associated with decreased Parkinson's disease prevalence in a large community-based surveyAndrea Winquist
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Mov Disord 25:932-6. 2010..78 mg/dl lower than the mean UA level among those not reporting PD (P <or= 0.0001). These findings concur with several previous longitudinal studies that found an association between higher UA levels and decreased PD risk...
A practical guide to dose-response analyses and risk assessment in occupational epidemiologyKyle Steenland
Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Epidemiology 15:63-70. 2004..Points are illustrated using data from a study of dioxin and cancer...
Exposures to diesel exhaust in the International Brotherhood of Teamsters, 1950-1990Chad R Bailey
Environmental Protection Agency, Office of Transportation and Air Quality, 2565 Plymouth Road, Ann Arbor, MI 48105, USA
AIHA J (Fairfax, Va) 64:472-9. 2003..Monte Carlo sampling is used to characterize exposure distributions. The methodology used in this article-a probabilistic model for historical exposure assessment-is novel...
Late-life depression as a risk factor for mild cognitive impairment or Alzheimer's disease in 30 US Alzheimer's disease centersKyle Steenland
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
J Alzheimers Dis 31:265-75. 2012..The effect of recent depression did not differ by antidepressant treatment, APOE4 allele status, or type of MCI. In conclusion, late-life depression is a strong risk factor for normal subjects progressing to MCI...
Cancer outcomes research in a rural area: a multi-institution partnership modelMichael Goodman
Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA 30322, USA
J Community Health 34:23-32. 2009..Our partnership model may provide a useful framework for cancer outcomes research projects in rural communities...
The global burden of non-malignant respiratory disease due to occupational airborne exposuresTimothy Driscoll
ELMATOM Pty Ltd, Sydney, Australia
Am J Ind Med 48:432-45. 2005..We describe the worldwide mortality and morbidity from asthma, chronic obstructive pulmonary disease (COPD), and pneumoconioses arising from these occupational exposure and focus on cases reported in the year 2000...
The association between late-life depression, mild cognitive impairment and dementia: is inflammation the missing link?Adriana P Hermida
Department of Psychiatry and Behavioral Science, Emory University School of Medicine, Wesley Woods Health Center, 4th Floor, 1841 Clifton Road, NE, Atlanta, GA 30329, USA
Expert Rev Neurother 12:1339-50. 2012..The diagnostic challenges, the importance of biomarkers and the discussion of inflammation as a possible link between depression, MCI and dementia are examined in this article...
Association between polychlorinated biphenyls and Parkinson's disease neuropathologyJaime M Hatcher-Martin
Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA 30322, United States Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, United States
Neurotoxicology 33:1298-304. 2012..Furthermore, these data support epidemiological and laboratory studies reporting a link between PCB exposure and an increased risk for Parkinson's disease, including greater susceptibility of females...
Carcinogenicity of EBDCsKyle Steenland
Environ Health Perspect 111:A266; author reply A266-7. 2003
Costs of needlestick injuries and subsequent hepatitis and HIV infectionJ Paul Leigh
Center for Healthcare Policy and Research and Department of Public Health Sciences, University of California, Davis, CA 95616 8638, USA
Curr Med Res Opin 23:2093-105. 2007..Physicians, nurses and other healthcare workers (HCWs) are at risk of bloodborne pathogens infection from needlestick injuries, but costs of needlesticks are little studied...
Research Grants
- Mortality and Renal Disease in a Cohort Study of Lead-Exposed Workers in a SurveiNELSON STEENLAND; Fiscal Year: 2009..The proposed study would be the far larger than any prior cohort study of lead- exposed subjects, and will provide a model of collaboration across state-based surveillance systems. ..
- Mortality and Renal Disease in a Cohort Study of Lead-Exposed Workers in a SurveiNELSON K STEENLAND; Fiscal Year: 2010..The proposed study would be the far larger than any prior cohort study of lead- exposed subjects, and will provide a model of collaboration across state-based surveillance systems. ..
