Leslie Real

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc Rabies virus in raccoons, Ohio, 2004
    J Caroline Henderson
    Emory University, Atlanta, Georgia, USA
    Emerg Infect Dis 14:650-2. 2008
  2. pmc Predictive spatial dynamics and strategic planning for raccoon rabies emergence in Ohio
    Colin A Russell
    Department of Zoology, University of Cambridge, United Kingdom
    PLoS Biol 3:e88. 2005
  3. pmc Unifying the spatial population dynamics and molecular evolution of epidemic rabies virus
    Leslie A Real
    Department of Biology and Center for Disease Ecology, 1510 Clifton Road, Emory University, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 102:12107-11. 2005
  4. ncbi request reprint Infectious disease modeling and the dynamics of transmission
    L A Real
    Department of Biology and Center for Disease Ecology, Emory University, Atlanta, GA 30322, USA
    Curr Top Microbiol Immunol 315:33-49. 2007
  5. pmc Spatial dynamics and genetics of infectious diseases on heterogeneous landscapes
    Leslie A Real
    Department of Biology and the Center for Disease Ecology, Emory University, Atlanta, GA 30322, USA
    J R Soc Interface 4:935-48. 2007
  6. ncbi request reprint Spatial dynamics and molecular ecology of North American rabies
    L A Real
    Department of Biology and Center for Disease Ecology, Emory University, 1510 Clifton Rd NE, Atlanta, GA 30322, USA
    J Hered 96:253-60. 2005
  7. pmc The community-wide dilemma of hospital-acquired drug resistance
    Leslie A Real
    Department of Biology, Center for Disease Ecology, Emory University, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 102:2683-4. 2005
  8. pmc Transmission bottlenecks as determinants of virulence in rapidly evolving pathogens
    C T Bergstrom
    Department of Biology, Emory University, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 96:5095-100. 1999
  9. pmc Temporal dynamics of rabies in a wildlife host and the risk of cross-species transmission
    E R Gordon
    Department of Biology, Emory University, 1510 Clifton Road, Atlanta, GA 30322, USA
    Epidemiol Infect 132:515-24. 2004
  10. ncbi request reprint Persistence of elevated rabies prevention costs following post-epizootic declines in rates of rabies among raccoons (Procyon lotor)
    E R Gordon
    Department of Biology, Emory University, 1510 Clifton Road, Atlanta, GA 30322, USA
    Prev Vet Med 68:195-222. 2005

Collaborators

Detail Information

Publications20

  1. pmc Rabies virus in raccoons, Ohio, 2004
    J Caroline Henderson
    Emory University, Atlanta, Georgia, USA
    Emerg Infect Dis 14:650-2. 2008
    ..Our genetic investigation indicates that this outbreak may have begun several years before 2004 and may have originated within the vaccination zone...
  2. pmc Predictive spatial dynamics and strategic planning for raccoon rabies emergence in Ohio
    Colin A Russell
    Department of Zoology, University of Cambridge, United Kingdom
    PLoS Biol 3:e88. 2005
    ....
  3. pmc Unifying the spatial population dynamics and molecular evolution of epidemic rabies virus
    Leslie A Real
    Department of Biology and Center for Disease Ecology, 1510 Clifton Road, Emory University, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 102:12107-11. 2005
    ..The use of integrated approaches, such as the geographical analysis of sequence variants, coupled with information on spatial dynamics will become indispensable aids in understanding patterns of disease emergence...
  4. ncbi request reprint Infectious disease modeling and the dynamics of transmission
    L A Real
    Department of Biology and Center for Disease Ecology, Emory University, Atlanta, GA 30322, USA
    Curr Top Microbiol Immunol 315:33-49. 2007
    ..In particular, we highlight recent technical innovations that could help to overcome some the logistical challenges commonly associated with empirical disease research in wild populations...
  5. pmc Spatial dynamics and genetics of infectious diseases on heterogeneous landscapes
    Leslie A Real
    Department of Biology and the Center for Disease Ecology, Emory University, Atlanta, GA 30322, USA
    J R Soc Interface 4:935-48. 2007
    ....
  6. ncbi request reprint Spatial dynamics and molecular ecology of North American rabies
    L A Real
    Department of Biology and Center for Disease Ecology, Emory University, 1510 Clifton Rd NE, Atlanta, GA 30322, USA
    J Hered 96:253-60. 2005
    ....
  7. pmc The community-wide dilemma of hospital-acquired drug resistance
    Leslie A Real
    Department of Biology, Center for Disease Ecology, Emory University, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 102:2683-4. 2005
  8. pmc Transmission bottlenecks as determinants of virulence in rapidly evolving pathogens
    C T Bergstrom
    Department of Biology, Emory University, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 96:5095-100. 1999
    ..We argue that the patterns of accumulation of deleterious mutation may explain differing levels of virulence in vertically and horizontally transmitted diseases...
  9. pmc Temporal dynamics of rabies in a wildlife host and the risk of cross-species transmission
    E R Gordon
    Department of Biology, Emory University, 1510 Clifton Road, Atlanta, GA 30322, USA
    Epidemiol Infect 132:515-24. 2004
    ..Forecasting of the public health and veterinary burden of rabies and assessing the economics of control programmes, requires linking outcomes to dynamic, but predictable, changes in the temporal evolution of rabies epizootics...
  10. ncbi request reprint Persistence of elevated rabies prevention costs following post-epizootic declines in rates of rabies among raccoons (Procyon lotor)
    E R Gordon
    Department of Biology, Emory University, 1510 Clifton Road, Atlanta, GA 30322, USA
    Prev Vet Med 68:195-222. 2005
    ..The costs for rabies prevention activities reached apices during the epizootic stage of raccoon rabies (2.7-10.8 times baseline) an unforeseen finding indicated elevated costs persisted (1.7-7.2 times baseline) into the enzootic stage...
  11. ncbi request reprint Spatiotemporal analysis of epizootic raccoon rabies propagation in Connecticut, 1991-1995
    B T Lucey
    Department of Biology, Rollins School of Public Health, Emory University, Atlanta, Georgia 30345, USA
    Vector Borne Zoonotic Dis 2:77-86. 2002
    ....
  12. pmc Predicting the local dynamics of epizootic rabies among raccoons in the United States
    J E Childs
    Viral and Rickettsial Zoonoses Branch and Office of the Director, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road MSG13, Atlanta, GA 30333, USA
    Proc Natl Acad Sci U S A 97:13666-71. 2000
    ..These results encourage the use of data obtained through wildlife surveillance in assessing and refining epidemic models for wildlife diseases...
  13. pmc Isolates of Zaire ebolavirus from wild apes reveal genetic lineage and recombinants
    Tatiana J Wittmann
    Centre International de Recherches Medicales de Franceville, BP 769 Franceville, Gabon
    Proc Natl Acad Sci U S A 104:17123-7. 2007
    ..The potential for recombination adds an additional level of complexity to unraveling and potentially controlling the emergence of ZEBOV in humans and wildlife species...
  14. pmc Predicting the spatial dynamics of rabies epidemics on heterogeneous landscapes
    David L Smith
    Department of Epidemiology and Preventive Medicine, University of Maryland, 115 Howard Hall, 660 West Redwood Street, Baltimore, MD 21201, USA
    Proc Natl Acad Sci U S A 99:3668-72. 2002
    ....
  15. pmc A high-resolution genetic signature of demographic and spatial expansion in epizootic rabies virus
    Roman Biek
    Department of Biology and Center for Disease Ecology, Emory University, 1510 Clifton Road, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 104:7993-8. 2007
    ..Such approaches will be of increasing relevance for understanding the epidemiology of emerging zoonotic diseases in a landscape context...
  16. pmc Wave-like spread of Ebola Zaire
    Peter D Walsh
    Max Planck Institute for Evolutionary Primatology, Leipzig, Germany
    PLoS Biol 3:e371. 2005
    ..Controlling the impact of Ebola on wild apes and human populations may be more feasible than previously recognized...
  17. pmc A priori prediction of disease invasion dynamics in a novel environment
    Colin A Russell
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Proc Biol Sci 271:21-5. 2004
    ..These results have general implications for predicting future pathogen invasions and evaluating potential containment strategies...
  18. ncbi request reprint Optimal control of vaccine distribution in a rabies metapopulation model
    Erika Asano
    Environmental Science, Policy and Geography Univesity of South Florida, St Petersburg, FL 33701, USA
    Math Biosci Eng 5:219-38. 2008
    ..This strategy is chosen to limit the disease optimally by making the number of infections as small as possible while accounting for the cost of vaccination...
  19. pmc Recent common ancestry of Ebola Zaire virus found in a bat reservoir
    Roman Biek
    Center for Disease Ecology, Department of Biology, Emory University, Atlanta, Georgia, USA
    PLoS Pathog 2:e90. 2006
  20. ncbi request reprint Inferring the population structure and demographic history of the tick, Amblyomma americanum Linnaeus
    Tonya R Mixson
    Program in Population Biology, Ecology, and Evolution, Graduate Division of Biomedical and Biological Sciences, Emory University, Atlanta, GA 30322, USA
    J Vector Ecol 31:181-92. 2006
    ..Alternatively, the high degree of panmixia found within A. americanum in Georgia may be due to bird-mediated dispersal of ticks increasing the genetic similarity between geographically separated populations...