THADDEUS W PACE

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor
    Thaddeus W W Pace
    Department of Psychology and the Center for Neuroscience, University of Colorado at Boulder, Boulder, Colorado, USA
    Am J Physiol Endocrinol Metab 288:E1082-8. 2005
  2. ncbi A short review on the psychoneuroimmunology of posttraumatic stress disorder: from risk factors to medical comorbidities
    Thaddeus W W Pace
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
    Brain Behav Immun 25:6-13. 2011
  3. ncbi Activation of cAMP-protein kinase A abrogates STAT5-mediated inhibition of glucocorticoid receptor signaling by interferon-alpha
    Thaddeus W W Pace
    Department of Psychiatry and Behavioral Sciences, 1365 B Clifton Rd, Suite 5100, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Brain Behav Immun 25:1716-24. 2011
  4. ncbi Immediate-early gene induction in hippocampus and cortex as a result of novel experience is not directly related to the stressfulness of that experience
    Thaddeus W W Pace
    Department of Psychology, Campus Box 345, University of Colorado, Boulder, CO 80309, USA
    Eur J Neurosci 22:1679-90. 2005
  5. ncbi Differential glucocorticoid effects on stress-induced gene expression in the paraventricular nucleus of the hypothalamus and ACTH secretion in the rat
    Thaddeus W W Pace
    Department of Psychology, University of Colorado at Boulder, Boulder, CO, 80309 0345, USA
    Stress 12:400-11. 2009
  6. ncbi Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression
    Thaddeus W W Pace
    Department of Psychiatry and Behavioral Sciences, Winship Cancer Institute, Emory University School of Medicine, 101 Woodruff Cricle, Suite 4000, Atlanta, GA 30322, USA
    Brain Behav Immun 21:9-19. 2007
  7. ncbi Interferon-alpha inhibits glucocorticoid receptor-mediated gene transcription via STAT5 activation in mouse HT22 cells
    Fang Hu
    Department of Psychiatry and Behavioral Sciences, 1365 C Clifton Rd, 5th Floor, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Brain Behav Immun 23:455-63. 2009
  8. ncbi Cytokines and glucocorticoid receptor signaling. Relevance to major depression
    Thaddeus W W Pace
    Department of Psychiatry and Behavioral Sciences, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA
    Ann N Y Acad Sci 1179:86-105. 2009
  9. ncbi A new function of the leptin receptor: mediation of the recovery from lipopolysaccharide-induced hypothermia
    Alexandre A Steiner
    Systemic Inflammation Laboratory, Trauma Research, St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA
    FASEB J 18:1949-51. 2004

Research Grants

  1. Mineralocorticoid-R Control of HPA Stress Response
    THADDEUS PACE; Fiscal Year: 2003

Collaborators

  • Andrew Miller
  • M Girotti
  • C Heim
  • Fang Hu
  • Alexandre A Steiner
  • Shreya Patel
  • David H Jennings
  • Andrei I Ivanov
  • Alla Y Rudaya
  • Linda R Watkins
  • Miles Orchinik
  • M Devrim Dogan
  • Andrej A Romanovsky

Detail Information

Publications9

  1. ncbi Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor
    Thaddeus W W Pace
    Department of Psychology and the Center for Neuroscience, University of Colorado at Boulder, Boulder, Colorado, USA
    Am J Physiol Endocrinol Metab 288:E1082-8. 2005
    ..These data suggest that MR may be necessary for glucocorticoid regulation of HPA axis activity during mild stressors, but not during stressors that result in a more robust CORT response...
  2. ncbi A short review on the psychoneuroimmunology of posttraumatic stress disorder: from risk factors to medical comorbidities
    Thaddeus W W Pace
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
    Brain Behav Immun 25:6-13. 2011
    ..This short article reviews immune alterations in PTSD, and considers possible mechanisms by which such changes may be related to neuroendocrine alterations and medical comorbidities of PTSD...
  3. ncbi Activation of cAMP-protein kinase A abrogates STAT5-mediated inhibition of glucocorticoid receptor signaling by interferon-alpha
    Thaddeus W W Pace
    Department of Psychiatry and Behavioral Sciences, 1365 B Clifton Rd, Suite 5100, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Brain Behav Immun 25:1716-24. 2011
    ....
  4. ncbi Immediate-early gene induction in hippocampus and cortex as a result of novel experience is not directly related to the stressfulness of that experience
    Thaddeus W W Pace
    Department of Psychology, Campus Box 345, University of Colorado, Boulder, CO 80309, USA
    Eur J Neurosci 22:1679-90. 2005
    ....
  5. ncbi Differential glucocorticoid effects on stress-induced gene expression in the paraventricular nucleus of the hypothalamus and ACTH secretion in the rat
    Thaddeus W W Pace
    Department of Psychology, University of Colorado at Boulder, Boulder, CO, 80309 0345, USA
    Stress 12:400-11. 2009
    ....
  6. ncbi Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression
    Thaddeus W W Pace
    Department of Psychiatry and Behavioral Sciences, Winship Cancer Institute, Emory University School of Medicine, 101 Woodruff Cricle, Suite 4000, Atlanta, GA 30322, USA
    Brain Behav Immun 21:9-19. 2007
    ....
  7. ncbi Interferon-alpha inhibits glucocorticoid receptor-mediated gene transcription via STAT5 activation in mouse HT22 cells
    Fang Hu
    Department of Psychiatry and Behavioral Sciences, 1365 C Clifton Rd, 5th Floor, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Brain Behav Immun 23:455-63. 2009
    ..Given the role of GR in depressive disorders, IFN-alpha effects on GR function in cells of hippocampal origin may contribute to HPA axis alterations and depressive symptoms in IFN-alpha-treated patients...
  8. ncbi Cytokines and glucocorticoid receptor signaling. Relevance to major depression
    Thaddeus W W Pace
    Department of Psychiatry and Behavioral Sciences, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA
    Ann N Y Acad Sci 1179:86-105. 2009
    ....
  9. ncbi A new function of the leptin receptor: mediation of the recovery from lipopolysaccharide-induced hypothermia
    Alexandre A Steiner
    Systemic Inflammation Laboratory, Trauma Research, St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA
    FASEB J 18:1949-51. 2004
    ....

Research Grants2

  1. Mineralocorticoid-R Control of HPA Stress Response
    THADDEUS PACE; Fiscal Year: 2003
    ..And finally, the role of MR in controlling HPA responding will be examined after a stressor has been experienced repeatedly, a situation previously shown to increase the number of brain MR. ..