Raul G Nogueira

Summary

Affiliation: Emory University
Country: USA

Publications

  1. doi request reprint Trevo versus Merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial
    Raul G Nogueira
    Department of Neurology, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA 30303, USA
    Lancet 380:1231-40. 2012
  2. ncbi request reprint Should clot composition affect choice of endovascular therapy?
    Brijesh P Mehta
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Neurology 79:S63-7. 2012
  3. ncbi request reprint North American SOLITAIRE Stent-Retriever Acute Stroke Registry: choice of anesthesia and outcomes
    Alex Abou-Chebl
    From the Texas Stroke Institute, Plano, TX A A C, V J Departments of Neurology, Neurosurgery, and Radiology, Medical College of Wisconsin Froedtert Hospital, Atlanta, GA O O Z, A C C, M A I Wellstar Neurosurgery Kennestone Hospital, Atlanta, GA R G Department of Neurology, Emory University School of Medicine, Atlanta, GA C H J S R G N Saint Luke s Kansas City, Kansas City, MO C O M, W E H Department of Neurology, Delray Medical Center, Delray Beach, FL N M K California Pacific Medical Center, San Francisco, CA J D E Division of Interventional Neuroradiology, Baptist Cardiac and Vascular Institute, Miami, FL I L, G D Alexian Brothers Medical Center, Elk Grove Village, IL T W M, F A M Oregon Health and Science University, Portland, OR H B Department of Neurology, Wayne State University School of Medicine, Detroit, MI A X Department of Radiology, West Virginia University Hospital, Morgantown, WV A T R Departments of Neurology
    Stroke 45:1396-401. 2014
  4. doi request reprint Comparison of final infarct volumes in patients who received endovascular therapy or intravenous thrombolysis for acute intracranial large-vessel occlusions
    Srikant Rangaraju
    Department of Neurology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, Georgia 30303, USA
    JAMA Neurol 70:831-6. 2013
  5. doi request reprint THRIVE score predicts outcomes with a third-generation endovascular stroke treatment device in the TREVO-2 trial
    Alexander C Flint
    From the Department of Neuroscience, Kaiser Permanente, Redwood City, CA A C F Department of Clinical Research, Prospect Analytical, San Jose, CA B X Departments of Neurology, Neurosurgery, and Radiology, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA R G, R G N Department of Neurology, Oregon Health and Science University, Portland, OR H L L Department of Neurology, UPMC Stroke Center, University of Pittsburgh Medical Center, PA T G J Department of Neurology, Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA G W A Department of Neurology, UCLA Stroke Center, University of California, Los Angeles, CA D S L Department of Neurology, University of Southern California, Los Angeles, CA N S and Department of Neurology, University of California, San Francisco, CA W S S
    Stroke 44:3370-5. 2013
  6. pmc Prestroke dementia is associated with poor outcomes after reperfusion therapy among elderly stroke patients
    Katharina M Busl
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Stroke Cerebrovasc Dis 22:718-24. 2013
  7. doi request reprint Endovascular Reperfusion and Cooling in Cerebral Acute Ischemia (ReCCLAIM I)
    Christopher M Horn
    Department of Neurology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, Georgia, USA
    J Neurointerv Surg 6:91-5. 2014
  8. ncbi request reprint Posttreatment variables improve outcome prediction after intra-arterial therapy for acute ischemic stroke
    Shyam Prabhakaran
    Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Ill, USA
    Cerebrovasc Dis 37:356-63. 2014
  9. doi request reprint Higher volume endovascular stroke centers have faster times to treatment, higher reperfusion rates and higher rates of good clinical outcomes
    Rishi Gupta
    Department of Neurology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA
    J Neurointerv Surg 5:294-7. 2013
  10. doi request reprint Safety of full-dose intravenous recombinant tissue plasminogen activator followed by multimodal endovascular therapy for acute ischemic stroke
    Raul G Nogueira
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Neurointerv Surg 5:298-301. 2013

Collaborators

Detail Information

Publications28

  1. doi request reprint Trevo versus Merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial
    Raul G Nogueira
    Department of Neurology, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA 30303, USA
    Lancet 380:1231-40. 2012
    ..We compared efficacy and safety of the Trevo Retriever, a new stent-like device, with its US Food and Drug Administration-cleared predecessor, the Merci Retriever...
  2. ncbi request reprint Should clot composition affect choice of endovascular therapy?
    Brijesh P Mehta
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Neurology 79:S63-7. 2012
    ..The objective of this article is to provide a review of clinical and experimental animal studies on the histology, imaging correlation, and ultrastructure of thromboemboli retrieved during acute ischemic stroke...
  3. ncbi request reprint North American SOLITAIRE Stent-Retriever Acute Stroke Registry: choice of anesthesia and outcomes
    Alex Abou-Chebl
    From the Texas Stroke Institute, Plano, TX A A C, V J Departments of Neurology, Neurosurgery, and Radiology, Medical College of Wisconsin Froedtert Hospital, Atlanta, GA O O Z, A C C, M A I Wellstar Neurosurgery Kennestone Hospital, Atlanta, GA R G Department of Neurology, Emory University School of Medicine, Atlanta, GA C H J S R G N Saint Luke s Kansas City, Kansas City, MO C O M, W E H Department of Neurology, Delray Medical Center, Delray Beach, FL N M K California Pacific Medical Center, San Francisco, CA J D E Division of Interventional Neuroradiology, Baptist Cardiac and Vascular Institute, Miami, FL I L, G D Alexian Brothers Medical Center, Elk Grove Village, IL T W M, F A M Oregon Health and Science University, Portland, OR H B Department of Neurology, Wayne State University School of Medicine, Detroit, MI A X Department of Radiology, West Virginia University Hospital, Morgantown, WV A T R Departments of Neurology
    Stroke 45:1396-401. 2014
    ..Previous work that predated the availability of the safer stent-retriever devices has suggested that general anesthesia (GA) may have a negative impact on outcomes in patients with acute ischemic stroke undergoing endovascular therapy...
  4. doi request reprint Comparison of final infarct volumes in patients who received endovascular therapy or intravenous thrombolysis for acute intracranial large-vessel occlusions
    Srikant Rangaraju
    Department of Neurology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, Georgia 30303, USA
    JAMA Neurol 70:831-6. 2013
    ..Studies comparing the efficacy of intra-arterial therapy (IAT) and medical therapy in reducing final infarct volume (FIV) in intracranial large-vessel occlusions (ILVOs) are lacking...
  5. doi request reprint THRIVE score predicts outcomes with a third-generation endovascular stroke treatment device in the TREVO-2 trial
    Alexander C Flint
    From the Department of Neuroscience, Kaiser Permanente, Redwood City, CA A C F Department of Clinical Research, Prospect Analytical, San Jose, CA B X Departments of Neurology, Neurosurgery, and Radiology, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA R G, R G N Department of Neurology, Oregon Health and Science University, Portland, OR H L L Department of Neurology, UPMC Stroke Center, University of Pittsburgh Medical Center, PA T G J Department of Neurology, Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA G W A Department of Neurology, UCLA Stroke Center, University of California, Los Angeles, CA D S L Department of Neurology, University of Southern California, Los Angeles, CA N S and Department of Neurology, University of California, San Francisco, CA W S S
    Stroke 44:3370-5. 2013
    ..The TREVO-2 trial was a randomized controlled trial comparing a novel endovascular stroke treatment device (the Trevo device) to a previous-generation endovascular stroke treatment device (the Merci device)...
  6. pmc Prestroke dementia is associated with poor outcomes after reperfusion therapy among elderly stroke patients
    Katharina M Busl
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Stroke Cerebrovasc Dis 22:718-24. 2013
    ..In elderly acute stroke patients, reperfusion therapy is often withheld. We sought to determine whether prestroke dementia contributed to poor outcomes after reperfusion therapy in these patients...
  7. doi request reprint Endovascular Reperfusion and Cooling in Cerebral Acute Ischemia (ReCCLAIM I)
    Christopher M Horn
    Department of Neurology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, Georgia, USA
    J Neurointerv Surg 6:91-5. 2014
    ..We conducted a phase I pilot study to assess the feasibility and safety of performing intravascular hypothermia after definitive intra-arterial reperfusion therapy (IAT)...
  8. ncbi request reprint Posttreatment variables improve outcome prediction after intra-arterial therapy for acute ischemic stroke
    Shyam Prabhakaran
    Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Ill, USA
    Cerebrovasc Dis 37:356-63. 2014
    ..Inclusion of posttreatment variables such as reperfusion and symptomatic hemorrhage greatly influences outcome and results in improved outcome prediction. © 2014 S. Karger AG, Basel. ..
  9. doi request reprint Higher volume endovascular stroke centers have faster times to treatment, higher reperfusion rates and higher rates of good clinical outcomes
    Rishi Gupta
    Department of Neurology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA
    J Neurointerv Surg 5:294-7. 2013
    ..Unfortunately, the sequence of events prior to reperfusion may lead to significant treatment delays. This study sought to determine if high-volume (HV) centers were efficient at delivery of endovascular treatment approaches...
  10. doi request reprint Safety of full-dose intravenous recombinant tissue plasminogen activator followed by multimodal endovascular therapy for acute ischemic stroke
    Raul G Nogueira
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Neurointerv Surg 5:298-301. 2013
    ..A study was undertaken to establish whether treatment with a standard intravenous t-PA dose (0.9 mg/kg) followed by multimodal endovascular therapy would have a similar safety profile to reduced dose (0.6 mg/kg) bridging therapy...
  11. ncbi request reprint Balloon guide catheter improves revascularization and clinical outcomes with the Solitaire device: analysis of the North American Solitaire Acute Stroke Registry
    Thanh N Nguyen
    From the Departments of Neurology T N N, H M, Neurosurgery T N N, and Radiology T N N, H M, A M N, Boston University School of Medicine, MA Alexian Brothers Medical Center, Elk Grove Village, IL T M, F A M Departments of Neurosurgery O O Z, Neurology A C C, M A I, O O Z, and Radiology O O Z, Medical College of Wisconsin, Milwaukee Department of Neurology, Emory University School of Medicine, Atlanta, GA R G, C H J S, R G N St Luke s Neuroscience Institute, Kansas City, MO C O M, W E H Department of Neurology, Delray Medical Center, Delray Beach, FL N M K California Pacific Medical Center, San Francisco J D E Division of Interventional Neuroradiology, Baptist Cardiac and Vascular Institute, Miami, FL I L, G D Oregon Health and Sciences, Portland H B Department of Neurology, Wayne State University School of Medicine, Detroit, Germany
    Stroke 45:141-5. 2014
    ..The goal of this study was to evaluate the role of the balloon guide catheter (BGC) and recanalization success in a substudy of the North American Solitaire Acute Stroke (NASA) registry...
  12. doi request reprint Effect of time to reperfusion on clinical outcome of anterior circulation strokes treated with thrombectomy: pooled analysis of the MERCI and Multi MERCI trials
    Raul G Nogueira
    Department of Neurology, Neurosurgery, and Radiology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA
    Stroke 42:3144-9. 2011
    ..We sought to establish how time influences outcomes in anterior circulation proximal arterial occlusions...
  13. doi request reprint Intra-arterial thrombolysis or stent placement during endovascular treatment for acute ischemic stroke leads to the highest recanalization rate: results of a multicenter retrospective study
    Rishi Gupta
    Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, Georgia 30303, USA
    Neurosurgery 68:1618-22; discussion 1622-3. 2011
    ..Reperfusion therapy for acute ischemic stroke (AIS) is rapidly evolving, with the development of multiple endovascular modalities that can be used alone or in combination...
  14. ncbi request reprint Dynamic contrast-enhanced MRA at 1.5 T for detection of arteriovenous shunting before and after Onyx embolization of cerebral arteriovenous malformations
    Raul G Nogueira
    Departments of Neurology Departments of Neurology, Neurosurgery, and Radiology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA
    J Neuroimaging 23:514-7. 2013
    ..We describe the use of dynamic contrast-enhanced magnetic resonance angiography (MRA) in the evaluation of residual arteriovenous shunting in cAVMs following Onyx embolization...
  15. ncbi request reprint Dexmedetomidine: a safe alternative to general anesthesia for endovascular stroke treatment
    Matthew K Whalin
    Department of Anesthesiology, Emory University, Atlanta, Georgia, USA
    J Neurointerv Surg 6:270-5. 2014
    ..Since traditional sedatives carry the risk of respiratory depression, this retrospective study was designed to compare sedation with the α2 adrenergic agonist dexmedetomidine (DEX) and with GA for IAT procedures...
  16. ncbi request reprint Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature
    Ashutosh P Jadhav
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Neurointerv Surg 5:562-5. 2013
    ..Onyx is a liquid non-adhesive viscous embolic agent ideal for slow targeted injections which is currently approved for the treatment of intracranial aneurysms and arteriovenous malformations...
  17. doi request reprint Advanced modality imaging evaluation in acute ischemic stroke may lead to delayed endovascular reperfusion therapy without improvement in clinical outcomes
    Kevin N Sheth
    Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Neurointerv Surg 5:i62-5. 2013
    ..We studied the effect of advanced modality imaging with CT perfusion (CTP) or MRI compared with non-contrast CT (NCT) in a multicenter cohort...
  18. doi request reprint Prospective, multicenter, single-arm study of mechanical thrombectomy using Solitaire Flow Restoration in acute ischemic stroke
    Vitor M Pereira
    From the Department of Neuroradiology V M P, and Department of Neurology R S, University Hospital of Geneva, Geneva, Switzerland Department for Diagnostic and Interventional Neuroradiology J G, G S, and Department of Neurology M A, Inselspital, University of Bern, Bern, Switzerland Department of Neurology A D, and Department of Neuroradiology C C, University Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain Department of Neuroradiology, CHU de Montpellier Guy de Chauliac, Montpellier, France A B Department of Neuroradiology, Alfred Krupp Krankenhaus, Essen, Germany R C Department of Neurology, UCLA Stroke Center, CA D S L Department of Neurology, Emory University School of Medicine, Atlanta, GA R G N Department of Neuroradiology, University Hospital of Cologne, Cologne, Germany T L Department for Neuroradiology, University of Calgary, Foothills Medical Centre, Calgary, AB, Canada M G Department of Neurology, Klinikum Osnabrueck, Osnabrueck, Germany M B and Department of Neuroradiology, Hospital Virgen de la Arrixaca, Murcia
    Stroke 44:2802-7. 2013
    ..We present the results of a large prospective study on the use of the Solitaire Flow Restoration in patients with acute ischemic stroke...
  19. doi request reprint The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion
    Fabricio O Lima
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Boston, Mass 02114, USA
    Stroke 41:2316-22. 2010
    ..The role of noninvasive methods in the evaluation of collateral circulation has yet to be defined. We hypothesized that a favorable pattern of leptomeningeal collaterals, as identified by CT angiography, correlates with improved outcomes...
  20. pmc Implementation of a patient selection protocol for intra-arterial therapy increases treatment rates in patients with acute ischemic stroke
    Natalia S Rost
    Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Neurointerv Surg 5:i44-7. 2013
    ..The degree of protocol adoption and treatment rates associated with implementation of a service-wide patient selection IAT protocol were assessed...
  21. doi request reprint Predictors of good clinical outcomes, mortality, and successful revascularization in patients with acute ischemic stroke undergoing thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI Trials
    Raul G Nogueira
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Stroke 40:3777-83. 2009
    ..We sought to determine the predictors of clinical and angiographic outcomes in these patients...
  22. doi request reprint Acute stroke: techniques and results with the Merci retriever
    Ali Reza Noorian
    Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA
    Tech Vasc Interv Radiol 15:47-52. 2012
    ..In this article, we review the indications for acute stroke endovascular treatment with the Merci retriever as well as the involved techniques and the results of research studies...
  23. doi request reprint "Picture to puncture": a novel time metric to enhance outcomes in patients transferred for endovascular reperfusion in acute ischemic stroke
    Chung Huan J Sun
    Department of Neurology, Emory University School of Medicine, Atlanta, GA 30303, USA
    Circulation 127:1139-48. 2013
    ..Efficacy of endovascular treatments, however, may be limited by delays in patient transfer. Our goal was to identify where these delays occurred and to assess the impact of such delays on patient outcome...
  24. doi request reprint The Trevo device: preclinical data of a novel stroke thrombectomy device in two different animal models of arterial thrombo-occlusive disease
    Raul G Nogueira
    Department of Neurology, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, Georgia, USA
    J Neurointerv Surg 4:295-300. 2012
    ..The currently available mechanical devices fail to achieve recanalization in as many as 20-40% of proximal arterial occlusion strokes...
  25. ncbi request reprint Conscious sedation versus general anesthesia during endovascular therapy for acute anterior circulation stroke: preliminary results from a retrospective, multicenter study
    Alex Abou-Chebl
    Department of Neurology, Vanderbilt Stroke Center, A 0118 Medical Center North, Nashville, TN 37232 2551, USA
    Stroke 41:1175-9. 2010
    ..We sought to determine whether there were differences in safety and outcomes in GA patients before initiation of IAT...
  26. doi request reprint Diagnosis and management of vertebrobasilar insufficiency
    Aaron Stayman
    Emory University School of Medicine, Department of Neurology, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, 49 Jesse Hill Jr Drive, SE, Faculty Office Bldg 393, Atlanta, GA, 30303, USA
    Curr Treat Options Cardiovasc Med 15:240-51. 2013
    ..In such circumstances, stenting and angioplasty may be considered. Intracranial atherosclerosis is best managed with maximal medical therapy due to the high rate of complications attributable to stenting and angioplasty...
  27. doi request reprint The neuro-critical care management of the endovascular stroke patient
    Vishal N Patel
    Department of Neurology, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Emory Faculty Office Building, 80 Jessee Hill Jr Drive, SE Room 398, Atlanta, GA, 30303, USA
    Curr Treat Options Neurol 15:113-24. 2013
    ..Because randomized prospective data is lacking, patients should be encouraged to enroll in clinical trials to optimize care of this growing patient population...
  28. doi request reprint Factor XIII deficiency related recurrent spontaneous intracerebral hemorrhage: a case and literature review
    David L Perez
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Neurol Neurosurg 113:142-5. 2011
    ..Early diagnosis and initiation of factor replacement therapy offer the best strategies to reduce the morbidities associated with this disease...