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Species | Nancy J NewmanSummaryAffiliation: Emory University Country: USA Publications
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Publications
Perioperative visual loss after nonocular surgeriesNancy J Newman
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Ophthalmol 145:604-610. 2008..To review the current knowledge of persistent visual loss after nonocular surgeries under general anesthesia...
Treatment of hereditary optic neuropathiesNancy J Newman
Neuro Ophthalmology Unit, Department of Ophthalmology, Neurology and Neurological Surgery, Emory University School of Medicine, 1365 B Clifton Road NE, Atlanta, GA 30322, USA
Nat Rev Neurol 8:545-56. 2012..In this Review, the natural history of the common inherited optic neuropathies, the presumed pathogenesis of several of these disorders, and the literature to date regarding potential therapies are summarized...
Mitochondrial oxidative phosphorylation in autosomal dominant optic atrophyVladimir I Mayorov
Division of Basic Medical Sciences, Mercer University School of Medicine, Macon, GA 31207, USA
BMC Biochem 9:22. 2008..While OPA1 has been characterized for its role in mitochondrial cristae structure and organelle fusion, possible effects of OPA1 on mitochondrial function have not been determined...
Magnetic resonance imaging abnormalities in cat-scratch disease encephalopathyAlvin B H Seah
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
J Neuroophthalmol 23:16-21. 2003..The variety of neuroimaging findings supports multiple pathophysiologic mechanisms of central nervous system involvement in this disorder...
The ischemic optic neuropathy decompression trialNancy J Newman
Department of Ophthalmology, Neurology, and Neurological Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
Arch Ophthalmol 125:1568-70. 2007
Hereditary optic neuropathies: from the mitochondria to the optic nerveNancy J Newman
Department of Ophthalmology, Emory University School of Medicine, Emory Eye Center, 1365 B Clifton Road NE, Atlanta, GA 30322, USA
Am J Ophthalmol 140:517-23. 2005..To review our current knowledge of inherited optic neuropathies...
Prophylaxis for second eye involvement in leber hereditary optic neuropathy: an open-labeled, nonrandomized multicenter trial of topical brimonidine puriteNancy J Newman
Department of Ophthalmology, Emory University School of Medicine, Emory Eye Center, 1365 B Clifton Road NE, Atlanta, GA 30322, USA
Am J Ophthalmol 140:407-15. 2005....
Progression of visual field defects in leber hereditary optic neuropathy: experience of the LHON treatment trialNancy J Newman
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA 30322, USA
Am J Ophthalmol 141:1061-1067. 2006..To describe the visual fields of patients with Leber hereditary optic neuropathy (LHON), a maternally inherited disorder characterized by bilateral, often sequential vision loss, before and during progressive visual deterioration...
Quality of nonmydriatic digital fundus photography obtained by nurse practitioners in the emergency department: the FOTO-ED studyCédric Lamirel
Department of Ophthalmology, Emory University, Atlanta, Georgia, USA
Ophthalmology 119:617-24. 2012..We evaluated the reliability of a novel quality rating scale and applied this scale to nonmydriatic fundus photographs taken during routine ED patient encounters to determine factors associated with diminished photograph quality...
Congruency in homonymous hemianopiaSachin Kedar
Department of Ophthalmology, Emory University, Atlanta, Georgia 30322, USA
Am J Ophthalmol 143:772-80. 2007..To evaluate the value of congruency in the localization of brain lesions in patients with homonymous hemianopia (HH)...
Nonmydriatic ocular fundus photography among headache patients in an emergency departmentPraneetha Thulasi
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
Neurology 80:432-7. 2013..Determine the frequency of and the predictive factors for abnormal ocular fundus findings among emergency department (ED) headache patients...
Feasibility and quality of nonmydriatic fundus photography in childrenDaniela Toffoli
Department of Ophthalmology, Emory University, Atlanta, Georgia 30822, USA
J AAPOS 15:567-72. 2011..Ocular funduscopic examination is difficult in young children and is rarely attempted by nonophthalmologists. Our objective was to determine the feasibility of reliably obtaining high-quality nonmydriatic fundus photographs in children...
Hypertension-related eye abnormalities and the risk of strokeAmanda D Henderson
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
Rev Neurol Dis 8:1-9. 2011....
Clinical course of idiopathic intracranial hypertension with transverse sinus stenosisBryan D Riggeal
From the Departments of Ophthalmology B D R, B B B, M A R, L P K, N J N, V B, Neurology B B B, N J N, V B, Neurological Surgery N J N, and Radiology and Imaging Sciences A M S, Emory University School of Medicine and Rollins School of Public Health and Laney Graduate School B B B, Emory University, Atlanta, GA
Neurology 80:289-95. 2013..We evaluated differences in TSS characteristics between patients with IIH with "good" vs "poor" clinical courses...
Management of optic neuritis and impact of clinical trials: an international surveyValerie Biousse
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA 30322, USA
J Neurol Sci 276:69-74. 2009..1) To evaluate the management of acute isolated optic neuritis (ON) by ophthalmologists and neurologists; 2) to evaluate the impact of clinical trials; 3) to compare these practices among 7 countries...
The Berlin questionnaire screens for obstructive sleep apnea in idiopathic intracranial hypertensionMatthew J Thurtell
Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, Iowa, USA
J Neuroophthalmol 31:316-9. 2011..The Berlin questionnaire (BQ) reliably identifies middle-aged and older persons in the community who are at high-risk for OSA. We aimed to validate the BQ as a screening tool for OSA in IIH patients...
Fulminant idiopathic intracranial hypertensionMadhav Thambisetty
Departments of Neurology, Emory University, Atlanta, GA, USA
Neurology 68:229-32. 2007..To describe the incidence and characteristics of acute and rapidly progressive visual loss in idiopathic intracranial hypertension (IIH)...
The neuro-ophthalmology of mitochondrial diseaseJ Alexander Fraser
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Surv Ophthalmol 55:299-334. 2010..Most patients and their relatives benefit from informed genetic counseling...
An update on idiopathic intracranial hypertensionMatthew J Thurtell
Department of Ophthalmology, Emory University, Atlanta, GA, USA
Rev Neurol Dis 7:e56-68. 2010..Ongoing studies of venous anatomy and physiology in IIH patients, as well as a recently begun randomized clinical treatment trial, should provide further insight into this common yet poorly understood syndrome...
Treatment of nonarteritic anterior ischemic optic neuropathyEdward J Atkins
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Surv Ophthalmol 55:47-63. 2010..Similarly, therapies aimed at secondary prevention of fellow eye involvement in NAION remain of unproven benefit...
Risk factors for idiopathic intracranial hypertension in men: a case-control studyJ Alexander Fraser
Department of Ophthalmology, Emory University, Atlanta, GA, USA
J Neurol Sci 290:86-9. 2010..To identify risk factors for idiopathic intracranial hypertension (IIH) in men...
A patient with acute visual loss and transient neurologic symptoms. Diagnosis: an acute central retinal artery occlusion (CRAO) in the left eye with severe retinal ischemiaJohnstone M Kim
Department of Ophthalmology, Emory University, Atlanta, GA, USA
Rev Neurol Dis 7:e89-90; discussion e98-101. 2010..A 73-year-old man presented with acute visual loss in his left eye associated with transient left upper extremity numbness. Diagnosis was made in the emergency room, where treatment strategies were discussed...
Genetic screening for OPA1 and OPA3 mutations in patients with suspected inherited optic neuropathiesPatrick Yu-Wai-Man
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Ophthalmology 118:558-63. 2011..The aim of this study was to determine the yield of OPA1 and OPA3 screening in a cohort of presumed DOA cases referred to a tertiary diagnostic laboratory...
Homonymous hemianopia in strokeXiaojun Zhang
Departments of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
J Neuroophthalmol 26:180-3. 2006..The configuration of the HH does not predict the location of the lesion within the retrochiasmal visual pathway...
Disorders of the optic tract, radiation, and occipital lobeJ Alexander Fraser
Departments of Ophthalmology, Neurology, and Neurological Surgery, Neuro Ophthalmology Unit, Emory Eye Center, Emory University School of Medicine, Atlanta, GA 30322, USA
Handb Clin Neurol 102:205-21. 2011..Although treatment options are limited to those of the underlying cause, appropriate counseling and low-vision rehabilitation may be helpful...
Visual function in anterior ischemic optic neuropathy: effect of Vision Restoration Therapy--a pilot studyCecilia S Jung
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
J Neurol Sci 268:145-9. 2008..To evaluate the effects of Vision Restoration Therapy (VRT) on the visual function of patients with anterior ischemic optic neuropathy...
Pediatric homonymous hemianopiaSachin Kedar
Department of Ophthalmology, Emory University, Atlanta, GA 30322, USA
J AAPOS 10:249-52. 2006..Although spontaneous improvement can be expected in approximately one third to one half of patients within the first few months, the recognition of homonymous hemianopia frequently is delayed in this population...
Grade III or Grade IV Hypertensive Retinopathy with Severely Elevated Blood PressureAmanda D Henderson
Emory University School of Medicine, Department of Ophthalmology, Atlanta, Georgia
West J Emerg Med 13:529-34. 2012....
Optic nerve head drusen in black patientsMatthew J Thurtell
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
J Neuroophthalmol 32:13-6. 2012..We aimed to determine the percentage of patients with ONHD who are black and to describe the clinical, ophthalmoscopic, and perimetric findings in these patients...
Update on the pathophysiology and management of idiopathic intracranial hypertensionValerie Biousse
Department of Ophthalmology, Emory University, Atlanta, GA, USA
J Neurol Neurosurg Psychiatry 83:488-94. 2012..However, many questions remain regarding the efficacy of acetazolamide, CSF shunting procedures and cerebral transverse venous sinus stenting...
Most cases labeled as "retinal migraine" are not migraineDonna L Hill
Departments of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
J Neuroophthalmol 27:3-8. 2007....
Multiple brain infarcts after orbital inflammationKatie Luneau
Department of Ophthalmology, Emory University, School of Medicine, Atlanta, GA, USA
Rev Neurol Dis 6:E75-6. 2009..Medical therapy improved her ophthalmoplegia, but she developed a right hemiparesis and aphasia...
Vision loss: overviewValerie Biousse
Department of Ophthalmology Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
Semin Neurol 27:199-210. 2007..However, a detailed ocular examination is always necessary before obtaining further neurological workup...
Feasibility of nonmydriatic ocular fundus photography in the emergency department: Phase I of the FOTO-ED studyBeau B Bruce
Department of Ophthalmology, Emory University, Atlanta, GA, USA
Acad Emerg Med 18:928-33. 2011..The objective was to examine the feasibility of nonmydriatic fundus photography as a clinical alternative to direct ophthalmoscopy by emergency physicians (EPs)...
A patient with headache and increased intracranial pressureDonna L Hill
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
Rev Neurol Dis 5:95-6. 2008
A patient with headache and increased intracranial pressureDonna L Hill
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
Rev Neurol Dis 5:90-1. 2008..These 2 cases presented with acutely raised intracranial pressure and had characteristic CT and MRI changes...
Headaches, rapidly progressive visual loss, and bilateral disc edemaCarrie R Muh
Department of Neurological Surgery, Emory University School of Medicine, Atlanta, GA, USA
Rev Neurol Dis 6:E133-4; discussion E141-5. 2009..Results of her initial general examination were normal. Thorough medical follow-up resulted in a rare diagnosis...
Minocycline-induced fulminant intracranial hypertensionClare L Fraser
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Arch Neurol 69:1067-70. 2012..To describe the clinical course of an unusually severe case of minocycline-induced intracranial hypertension...
Lesions of the optic nerveEdward J Atkins
Department of Ophthalmology, Neuro Ophthalmology Unit, Emory Eye Center, Emory University School of Medicine, Atlanta, GA 30322, USA
Handb Clin Neurol 102:159-84. 2011..Specific ancillary tests, especially new imaging modalities, help further localization and differential diagnosis...
Advances in neuro-ophthalmologyValerie Biousse
Emory Eye Center, Emory University School of Medicine, Atlanta, GA, USA
Rev Neurol Dis 4:92-6. 2007..Highlights from the 33rd Annual Meeting of the North American Neuro-Ophthalmology Society, Snowbird, UT, February 10-15, 2007...
Vascular neuro-ophthalmologyCédric Lamirel
Department of Ophthalmolgy, Emory Eye Center, 1365 B Clifton Road, NE Atlanta, GA 30322, USA
Neurol Clin 28:701-27. 2010..Funduscopic examination allows direct visualization of the retinal circulation, which shares many common characteristics with the cerebral microcirculation, and can be used as a marker of vascular disease...
Neurologic and ophthalmic manifestations of fetal alcohol syndromeBeau B Bruce
Departments of Ophthalmology and Neurology, Emory University School of Medicine, Atlanta, GA, USA
Rev Neurol Dis 6:13-20. 2009....
Update on idiopathic intracranial hypertensionBeau B Bruce
Department of Ophthalmology, Emory University, Atlanta, Georgia, USA
Am J Ophthalmol 152:163-9. 2011..To provide an update on various features of idiopathic intracranial hypertension...
Clinicopathologic correlations in giant cell arteritis: a retrospective study of 107 casesLing Zhou
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Ophthalmology 116:1574-80. 2009..To correlate the pathologic findings of temporal artery biopsies in patients clinically defined as positive, presumed, or negative for giant cell arteritis (GCA)...
The fellow eye in NAION: report from the ischemic optic neuropathy decompression trial follow-up studyNancy J Newman
Department of Ophthalmology, Neurology, and Neurological Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Ophthalmol 134:317-28. 2002..7% of IONDT patients over approximately 5 years. Increased incidence is associated with poor baseline visual acuity in the study eye and diabetes, but not age, sex, smoking history, or aspirin use...
Can Swedish interactive thresholding algorithm fast perimetry be used as an alternative to goldmann perimetry in neuro-ophthalmic practice?Gabriella Szatmáry
Neuro Ophthalmology Unit, Emory Eye Center, 1365 B Clifton Rd NE, Atlanta, GA 30322, USA
Arch Ophthalmol 120:1162-73. 2002....
Cat-scratch encephalopathyAlvin B H Seah
Department of Ophthalmology, Emory University School of Medicine, 1365-B Clifton Road NE, Atlanta, GA 30322, USA
Arch Neurol 61:145-7. 2004
Images in clinical medicine. Regression of optociliary shunt vesselsAdrienne Ruth
Emory University School of Medicine, Atlanta, GA 30322, USA
N Engl J Med 355:1262. 2006
Functional visual lossBeau B Bruce
Department of Ophthalmology and Neurology, Emory University School of Medicine, 1365 B Clifton Road, NE, Atlanta, GA 30322, USA
Neurol Clin 28:789-802. 2010..The relationship of true psychological disease and functional visual loss is unclear, and most patients respond well to simple reassurance...
Underdiagnosis of posterior communicating artery aneurysm in noninvasive brain vascular studiesValerie I Elmalem
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
J Neuroophthalmol 31:103-9. 2011..The aim of our study was to review the diagnostic strategies used to evaluate patients with isolated aneurysmal third nerve palsy at a large academic center...
OPA1 mutations and mitochondrial DNA haplotypes in autosomal dominant optic atrophyJian Han
Department of Basic Medical Sciences, Mercer University School of Medicine, Macon, GA, USA
Genet Med 8:217-25. 2006..The purpose of this study was therefore to determine if the background mtDNA genotype acts as a genetic modifier for the expression of this disease...
Subretinal hemorrhage from a peripapillary choroidal neovascular membrane in papilledema caused by idiopathic intracranial hypertensionBusaba Sathornsumetee
Department of Ophthalmology, and Neurological Surgery (NJN, Emory University, Atlanta, Georgia, USA
J Neuroophthalmol 26:197-9. 2006..Visual function did not improve after the surgery. CNVM can complicate chronic papilledema and account for sudden worsening of vision. The appropriate management of this type of CNVM is unresolved...
Diffusion-weighted magnetic resonance imaging in Shaken Baby SyndromeValerie Biousse
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Ophthalmol 133:249-55. 2002..To evaluate the role of diffusion-weighted magnetic resonance imaging (DWIMRI) in the diagnosis and management of children with suspected or confirmed Shaken Baby Syndrome (SBS)...
Neuro-ophthalmology of mitochondrial diseasesValerie Biousse
Departments of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Curr Opin Neurol 16:35-43. 2003..To review recent data on mitochondrial diseases with emphasis on their neuro-ophthalmic manifestations...
Optic nerve glioma and optic neuritis mimicking one another: case reportLuis M Tumialan
Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA
Neurosurgery 57:E190; discussion E190. 2005..We present two cases illustrating the occasional difficulty one can encounter in distinguishing neoplastic from inflammatory optic neuropathies...
Vascular damage in giant cell arteritisKisha Piggott
Lowance Center for Human Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
Autoimmunity 42:596-604. 2009..Differences in vascular damage pattern encountered in different patients may relate to distinct instigators of vasculitis...
Anemia and papilledemaValerie Biousse
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Ophthalmol 135:437-46. 2003..To elucidate the relationship between anemia and raised intracranial pressure (ICP)...
Ischemic optic neuropathiesKatie Luneau
Departments of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia
Neurologist 14:341-54. 2008..Posterior ischemic neuropathy (in which the optic nerve is normal acutely) is rare and should be considered a diagnosis of exclusion...
A case of acute posterior multifocal placoid pigment epitheliopathy with recurrent strokeKatie Luneau
Departments of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Neuroophthalmol 29:111-8. 2009..Because neurologic complications of APMPPE are rare, it is reasonable to reserve neuroimaging for patients who have unusual headaches or other new neurologic manifestations...
Thrombolysis for central retinal artery occlusionValerie Biousse
Department of Ophthalmology, Neuro Ophthalmology Unit, Emory University, 1365 B Clifton Road, Atlanta, GA 30322, USA
J Neuroophthalmol 27:215-30. 2007..Even if this trial demonstrates a benefit, thrombolytic treatment is unlikely to become widespread in the management of CRAO unless it can be deployed quickly after the event...
The diagnosis of giant cell arteritisMark R Melson
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
Rev Neurol Dis 4:128-42. 2007..We systematically review the diagnostic modalities used in suspected GCA patients who present with neuro-ophthalmic symptoms and signs...
Arachnoid cyst of the optic nerve: report of two cases and review of the literatureCharlotte Akor
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Ophthal Plast Reconstr Surg 19:466-9. 2003..The clinicopathologic features of arachnoid cyst should be differentiated from optic nerve sheath meningioma and other conditions...
Idiopathic intracranial hypertension: relation between obesity and visual outcomesAimee J Szewka
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
J Neuroophthalmol 33:4-8. 2013..Increased body mass index (BMI) has been associated with increased risk of idiopathic intracranial hypertension (IIH), but the relationship of BMI to visual outcomes in IIH is unclear...
Vitreous hemorrhage secondary to optociliary shunt vessels from papilledemaClare L Fraser
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA 30322, USA
J Neuroophthalmol 32:332-4. 2012..Optic nerve sheath fenestration was performed in an effort to promote regression of the papilledema and the shunt vessels. Our case illustrates a rare complication of optociliary shunt vessels in the setting of papilledema...
The use of retinal photography in nonophthalmic settings and its potential for neurologyMario A Pérez
Department of Ophthalmology, Emory University, Atlanta, GA, USA
Neurologist 18:350-5. 2012..Recent studies have suggested that digital retinal photography can replace direct ophthalmoscopy in many settings...
Hypertensive brainstem encephalopathy: clinical and radiographic featuresMadhav Thambisetty
Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA
J Neurol Sci 208:93-9. 2003..The clinical findings and neuroimaging abnormalities resolve with treatment of the hypertension, further distinguishing this syndrome from brainstem infarction...
Simultaneous bilateral retinal artery occlusions associated with a mitral valve massSachin Kedar
Department of Ophthalmology, Emory University, Atlanta, Georgia 30322, USA
J Neuroophthalmol 25:215-6. 2005..Such cases should be evaluated not merely by trans-thoracic echocardiography, but by trans-esophageal echocardiography, which better visualizes the aortic arch and left heart cavities...
Intracranial vascular anomalies in patients with morning glory disk anomalyPhoebe D Lenhart
Department of Pediatric Ophthalmology, Emory Eye Center, Atlanta, GA 30322, USA
Am J Ophthalmol 142:644-50. 2006..Follow-up imaging should be considered in patients with cerebrovascular anomalies and is clearly indicated if neurologic signs or symptoms are present...
Leptomeningeal enhancement and venous abnormalities in granulomatous angiitis of the central nervous systemJanet C Rucker
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
J Neuroophthalmol 23:148-50. 2003..This case, therefore, extends the pathologic and imaging spectrum of this disorder...
Posttraumatic cerebrospinal fluid hypertension and hypotensionTanya N Turan
Department of Neurology, Emory Eye Center, Emory University School of Medicine, 1365-B Clifton Road NE, Atlanta, GA 30322, USA
Arch Neurol 61:1124-5. 2004
The neuro-ophthalmology of pituitary tumorsVaninder S Chhabra
Department of Neurological Surgery, Emory University School of Medicine, Atlanta, GA, USA
Compr Ophthalmol Update 7:225-40; discussion 241-2. 2006..The goals of such treatment include the control of tumor growth, normalization of pituitary function, and preservation or restoration of visual function...
Visual outcomes after treatment of pituitary adenomasClare Louise Fraser
Department of Neuro Ophthalmology, Emory Eye Center, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA
Neurosurg Clin N Am 23:607-19. 2012..Treatments themselves may also cause neuro-ophthalmic complications. The current literature and avenues of future research are reviewed...
Voluntary alteration of full-field electroretinogramAlyson B Reiss
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
Am J Ophthalmol 139:571-2. 2005..These results confirm that abnormal full-field ERGs indicate true retinal disease...
The eyes of mito-mouse: mouse models of mitochondrial diseaseValerie Biousse
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
J Neuroophthalmol 22:279-85. 2002..In this article, we describe the currently available mouse models for mitochondrial diseases with special emphasis on their ocular phenotype. These mouse models demonstrate multiple and varied ophthalmologic manifestations...
Third nerve palsiesBeau B Bruce
Department of Ophthalmology Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
Semin Neurol 27:257-68. 2007..Recent advances in noninvasive neuroimaging facilitate early diagnosis, but the management of a patient presenting with isolated third nerve palsy remains a challenge...
MRI findings in isolated spontaneous thrombosis of the superior ophthalmic veinTodd Abruzzo
Department of Radiology, Section of Interventional Neuroradiology, Neuroscience Institute, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Rev Neurol Dis 4:161-5. 2007..The diagnosis was established by noncontrast CT scanning, gadolinium-enhanced MRI, and conventional catheter angiography...
From genotype to phenotype in Leber hereditary optic neuropathy: still more questions than answersNancy J Newman
J Neuroophthalmol 22:257-61. 2002
Optic nerve enhancement in leber hereditary optic neuropathy: four years laterMichael S Vaphiades
J Neuroophthalmol 22:66-7. 2002
Ischemic optic neuropathiesJanet C Rucker
Departments of Neurology and Ophthalmology, Case Western Reserve School of Medicine, Cleveland, Ohio, USA
Curr Opin Neurol 17:27-35. 2004....
Morbidity and mortality following pallidotomy in PDValerie Biousse
Neurology 59:1822; author reply 1822. 2002
Diagnosis and management of MELASMadhav Thambisetty
Department of Neurology, Institute of Psychiatry, King s College London, UK
Expert Rev Mol Diagn 4:631-44. 2004..Newer reproductive technologies hold promise for reducing the recurrence of MELAS in subsequent generations. Advances in research into gene therapy offer hope of treatment for the future...
Post-traumatic visual lossEdward J Atkins
Division of Neurology, University of Saskatchewan, Saskatoon, SK, Canada
Rev Neurol Dis 5:73-81. 2008..This review provides an update on the diagnosis and management of these conditions...
Anterior ischemic optic neuropathy in patients younger than 50 yearsPisit Preechawat
Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Thailand
Am J Ophthalmol 144:953-60. 2007..To characterize anterior ischemic optic neuropathy (AION) in patients younger than 50 years...
Optic neuritisEdward J Atkins
Division of Neurology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Semin Neurol 27:211-20. 2007..High-dose steroids hasten the rate, but not the final extent, of visual recovery in optic neuritis, and the decision to use this therapy is individualized. Interferon therapy should be considered in selected high-risk patients...
Heritable features of the optic disc: a novel twin method for determining genetic significanceAlex W Hewitt
Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia
Invest Ophthalmol Vis Sci 48:2469-75. 2007..Numerous genetic diseases and environmental stimuli affect optic nerve morphology. The purpose of this study was to identify the principal heritable components of visible optic nerve head structures in a population-based sample of twins...
Ophthalmoparesis in idiopathic intracranial hypertensionBeau B Bruce
Department of Neurology, Massachusetts General Hospital, Harvard University School of Medicine, Boston, Massachusetts, USA
Am J Ophthalmol 142:878-80. 2006..CONCLUSIONS: These exceptional vertical and horizontal ophthalmopareses in the setting of IIH may be related directly to very elevated CSF pressures and may be secondary to altered CSF flow in the posterior fossa...
The American Society of Anesthesiologists Postoperative Visual Loss Registry: analysis of 93 spine surgery cases with postoperative visual lossLorri A Lee
Departments of Anesthesiology and Neurological Surgery Adjunct, University of Washington, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104, USA
Anesthesiology 105:652-9; quiz 867-8. 2006..Postoperative visual loss after prone spine surgery is increasingly reported in association with ischemic optic neuropathy, but its etiology is unknown...
Eliminating the Ant1 isoform produces a mouse with CPEO pathology but normal ocular motilityHang Yin
Atlanta VA Medical Center, Decatur, Georgia 30033, USA
Invest Ophthalmol Vis Sci 46:4555-62. 2005..Because the extraocular muscles (EOM) are preferentially affected in human CPEO, the objective of this study was to determine whether Ant1-/- mice also exhibit an EOM mitochondrial myopathy...
The role of the ND5 gene in LHON: characterization of a new, heteroplasmic LHON mutationVladimir Mayorov
Division of Basic Medical Sciences, Mercer University School of Medicine, Macon, GA 31207, USA
Ann Neurol 58:807-11. 2005..The 12848T mutation alters a highly conserved amino acid in the ND5 complex I gene, is not found in controls, and is heteroplasmic. Despite ND5 being the largest of the mtDNA complex I genes, ND5 mutations are quite rare in LHON...
Erectile dysfunction drugs and nonarteritic anterior ischemic optic neuropathyAndrew G Lee
Am J Ophthalmol 140:707-8. 2005
The natural history of optic neuritisEdward J Atkins
Department of Neurology, University of Saskatchewan, Saskatoon, SK, Canada
Rev Neurol Dis 3:45-56. 2006..High-dose steroids hasten the rate, but not the final extent, of visual recovery in optic neuritis, and the decision to use this therapy is individualized. Interferon beta-1a therapy should be considered in selected high-risk patients...
Transient monocular visual loss in two patients with impending central retinal vein occlusionR Keith Shuler
J Neuroophthalmol 25:152-4. 2005
Ischemic optic neuropathy following spine surgeryVivien T-G Ho
Pritzker School of Medicine, University of Chicago, Chicago, Illinois 60637, USA
J Neurosurg Anesthesiol 17:38-44. 2005..The etiology of postoperative ION remains incompletely understood. Potential strategies to avoid this complication are discussed...
The eye in neurological diseaseNeil R Miller
Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD 21287, USA
Lancet 364:2045-54. 2004..In other cases, recognition of the ocular abnormality can prevent permanent visual dysfunction...
Angiographic shaded surface display artifact falsely suggests ophthalmic artery stenosisMaria Woodward
J Neuroophthalmol 27:241-2. 2007
