Gretchen N Neigh

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc Not all depression is created equal: sex interacts with disease to precipitate depression
    Christina L Nemeth
    Emory University Department of Physiology, Atlanta, GA, USA
    Biol Sex Differ 4:8. 2013
  2. ncbi request reprint 3-aminobenzamide prevents restraint-evoked immunocompromise
    Gretchen N Neigh
    Department of Psychology, Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 19:351-6. 2005
  3. ncbi request reprint Exogenous pyruvate prevents stress-evoked suppression of mitogen-stimulated proliferation
    Gretchen N Neigh
    Departments of Neuroscience and Psychology, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 18:425-33. 2004
  4. pmc Anxiety after cardiac arrest/cardiopulmonary resuscitation: exacerbated by stress and prevented by minocycline
    Gretchen N Neigh
    Department of Psychology, The Ohio State University, Columbus, Ohio 30322, USA
    Stroke 40:3601-7. 2009
  5. pmc Cardiac arrest and cardiopulmonary resuscitation dysregulates the hypothalamic-pituitary-adrenal axis
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30322, USA
    J Cereb Blood Flow Metab 29:1673-82. 2009
  6. ncbi request reprint Cardiac arrest/cardiopulmonary resuscitation augments cell-mediated immune function and transiently suppresses humoral immune function
    Gretchen N Neigh
    Department of Psychology, The Ohio State University, Townshend Hall, Columbus, Ohio 43210, USA
    J Cereb Blood Flow Metab 25:1424-32. 2005
  7. ncbi request reprint Cardiac arrest with cardiopulmonary resuscitation reduces dendritic spine density in CA1 pyramidal cells and selectively alters acquisition of spatial memory
    Gretchen N Neigh
    Department of Psychology, Townshend Hall, 1885 Neil Avenue Mall, The Ohio State University, Columbus, OH 43210, USA
    Eur J Neurosci 20:1865-72. 2004
  8. ncbi request reprint Immune and stress responses in C57BL/6 and C3H/HeN mouse strains following photoperiod manipulation
    Michelle L Gatien
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Neuro Endocrinol Lett 25:267-72. 2004
  9. ncbi request reprint Pyruvate prevents restraint-induced immunosuppression via alterations in glucocorticoid responses
    Gretchen N Neigh
    Townshend Hall, 1885 Neil Avenue Mall, Columbus, Ohio 43210, USA
    Endocrinology 145:4309-19. 2004
  10. pmc Exposure to repeated maternal aggression induces depressive-like behavior and increases startle in adult female rats
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States
    Behav Brain Res 227:270-5. 2012

Collaborators

Detail Information

Publications25

  1. pmc Not all depression is created equal: sex interacts with disease to precipitate depression
    Christina L Nemeth
    Emory University Department of Physiology, Atlanta, GA, USA
    Biol Sex Differ 4:8. 2013
    ....
  2. ncbi request reprint 3-aminobenzamide prevents restraint-evoked immunocompromise
    Gretchen N Neigh
    Department of Psychology, Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 19:351-6. 2005
    ..These data suggest that PARP inhibitors may be useful to prevent compromised immune function in response to stressors...
  3. ncbi request reprint Exogenous pyruvate prevents stress-evoked suppression of mitogen-stimulated proliferation
    Gretchen N Neigh
    Departments of Neuroscience and Psychology, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 18:425-33. 2004
    ....
  4. pmc Anxiety after cardiac arrest/cardiopulmonary resuscitation: exacerbated by stress and prevented by minocycline
    Gretchen N Neigh
    Department of Psychology, The Ohio State University, Columbus, Ohio 30322, USA
    Stroke 40:3601-7. 2009
    ..The goal of this study was to determine the effects of prior exposure to chronic stress on ischemia-induced neuronal death, microglial activation, and anxiety-like behavior...
  5. pmc Cardiac arrest and cardiopulmonary resuscitation dysregulates the hypothalamic-pituitary-adrenal axis
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30322, USA
    J Cereb Blood Flow Metab 29:1673-82. 2009
    ..Therefore, sustained changes in activity of the HPA axis and the CRF system after CA/CPR may contribute to the postischemic increase in affective disorders...
  6. ncbi request reprint Cardiac arrest/cardiopulmonary resuscitation augments cell-mediated immune function and transiently suppresses humoral immune function
    Gretchen N Neigh
    Department of Psychology, The Ohio State University, Townshend Hall, Columbus, Ohio 43210, USA
    J Cereb Blood Flow Metab 25:1424-32. 2005
    ..These data highlight the potential impact of neuronal damage on cell-mediated immune function and the role of humoral immune activation in outcome after global ischemia...
  7. ncbi request reprint Cardiac arrest with cardiopulmonary resuscitation reduces dendritic spine density in CA1 pyramidal cells and selectively alters acquisition of spatial memory
    Gretchen N Neigh
    Department of Psychology, Townshend Hall, 1885 Neil Avenue Mall, The Ohio State University, Columbus, OH 43210, USA
    Eur J Neurosci 20:1865-72. 2004
    ..Data presented here suggest that morphological changes, such as spine density, that occur in neurons that survive CA/CPR may be associated with cognitive impairments...
  8. ncbi request reprint Immune and stress responses in C57BL/6 and C3H/HeN mouse strains following photoperiod manipulation
    Michelle L Gatien
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Neuro Endocrinol Lett 25:267-72. 2004
    ..The purpose of this study was to determine whether two different strains of mice, that are reproductively unresponsive to photoperiod, adjust immune function in response to photoperiod...
  9. ncbi request reprint Pyruvate prevents restraint-induced immunosuppression via alterations in glucocorticoid responses
    Gretchen N Neigh
    Townshend Hall, 1885 Neil Avenue Mall, Columbus, Ohio 43210, USA
    Endocrinology 145:4309-19. 2004
    ..Pyruvate prevents restraint-induced immunosuppression via alterations in the glucocorticoid response to restraint...
  10. pmc Exposure to repeated maternal aggression induces depressive-like behavior and increases startle in adult female rats
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States
    Behav Brain Res 227:270-5. 2012
    ....
  11. ncbi request reprint 2006 Curt P. Richter award winner: Social influences on stress responses and health
    A Courtney Devries
    Department of Psychology and Neuroscience, The Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    Psychoneuroendocrinology 32:587-603. 2007
    ..Taken together, these studies provide support for the detrimental effects of stress and identify potential mechanisms underlying the well-documented clinical observation that social support positively influences human health...
  12. pmc Psychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge
    Christopher J Barnum
    Department of Physiology, School of Medicine, Emory University, 615 Michael Street, Atlanta, GA 30324, USA
    J Neuroinflammation 9:9. 2012
    ..However, long-term outcomes of chronic psychological stressors that elicit a neuroinflammatory response remain unknown...
  13. doi request reprint The neurobiological toll of child abuse and neglect
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, USA
    Trauma Violence Abuse 10:389-410. 2009
    ..Recognition of the biological consequences and transgenerational impact of violence and abuse has critical importance for both disease research and public health policy...
  14. pmc Changes in the vascular area fraction of the hippocampus and amygdala are induced by prenatal dexamethasone and/or adult stress
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30322, USA
    J Cereb Blood Flow Metab 30:1100-4. 2010
    ..These data indicate that in addition to the well-documented stress-induced changes in neurons and glia, cerebral vasculature is also altered by exposure to stressors...
  15. ncbi request reprint Nyctohemeral differences in response to restraint stress in CD-1 and C57BL/6 mice
    Andrew K Hotchkiss
    Department of Psychology, The Ohio State University, 48A Townshend Hall, 1885 Neil Avenue Mall, Columbus, OH 43210, USA
    Physiol Behav 80:441-7. 2004
    ..These results suggest that the physiological response to restraint is similar in both strains. However, corticosterone responses to both restraint and food deprivation were highest during the transitional and dark phases...
  16. ncbi request reprint Social environment modulates photoperiodic immune and reproductive responses in adult male white-footed mice (Peromyscus leucopus)
    Leah M Pyter
    Department of Neuroscience, Institute of Behavioral Medicine Research, Ohio State University, Columbus, Ohio, USA
    Am J Physiol Regul Integr Comp Physiol 288:R891-6. 2005
    ..Together, these results suggest that social environment may have important modulatory effects on photoperiod-regulated immune responses in male white-footed mice...
  17. doi request reprint Microembolism infarcts lead to delayed changes in affective-like behaviors followed by spatial memory impairment
    Christina L Nemeth
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States
    Behav Brain Res 234:259-66. 2012
    ..Collectively, these data demonstrate that microembolism infarcts are sufficient to induce changes in affective-like behavior and these changes precede alterations in spatial memory...
  18. ncbi request reprint Sex and lineage interact to predict behavioral effects of chronic adolescent stress in rats
    Constance S Harrell
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, USA
    Behav Brain Res 248:57-61. 2013
    ..Collectively, these data indicate that selective breeding interacts with chronic stress exposure during adolescence to dictate behavioral outcomes...
  19. pmc Behavioral effects of chronic adolescent stress are sustained and sexually dimorphic
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, USA
    Horm Behav 60:112-20. 2011
    ....
  20. pmc Stress-induced sex differences: adaptations mediated by the glucocorticoid receptor
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA
    Horm Behav 62:210-8. 2012
    ..New considerations of glucocorticoid regulation through the co-chaperone complex in the brain will be vital to the development of treatment strategies for men and women afflicted by neuropsychiatric and somatic disorders...
  21. ncbi request reprint SSRI or CRF antagonism partially ameliorate depressive-like behavior after adolescent social defeat
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA
    Behav Brain Res 270:295-9. 2014
    ..These data suggest that CRF1 receptor antagonists may be a viable alternative for treatment of depressive behaviors in adolescents. ..
  22. pmc Prenatal exposure to escitalopram and/or stress in rats produces limited effects on endocrine, behavioral, or gene expression measures in adult male rats
    Chase H Bourke
    Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA
    Neurotoxicol Teratol 39:100-9. 2013
    ..Study design should be carefully considered before implications for human health are ascribed to prenatal exposure to stress or antidepressant medication. ..
  23. pmc Microembolism induces anhedonia but no detectable changes in white matter integrity in aged rats
    Christina L Nemeth
    Department of Psychiatry and Behavioral Science, Emory University, Atlanta, Georgia, United States of America Department of Physiology, Emory University, Atlanta, Georgia, United States of America
    PLoS ONE 9:e96624. 2014
    ..Together, data suggest that behavioral deficits are not the result of damage to brain regions or white matter tracts, rather the activity of other systems may underlie functional disruption and recovery. ..
  24. pmc Estradiol stimulates an anti-translocation expression pattern of glucocorticoid co-regulators in a hippocampal cell model
    Sanjana A Malviya
    Department of Physiology, Emory University, Atlanta, GA, United States
    Physiol Behav 122:187-92. 2013
    ..The results presented here illustrate that E2 generates an anti-translocation pattern of GR co-regulators in hippocampal cells. ..
  25. pmc Cardiac arrest/cardiopulmonary resuscitation increases anxiety-like behavior and decreases social interaction
    Gretchen N Neigh
    Department of Psychology, The Ohio State University, Columbus 43210, USA
    J Cereb Blood Flow Metab 24:372-82. 2004
    ....