Gretchen N Neigh

Summary

Affiliation: Emory University
Country: USA

Publications

  1. doi request reprint Translational reciprocity: bridging the gap between preclinical studies and clinical treatment of stress effects on the adolescent brain
    G N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, 101 Woodruff Circle, Suite 4000, Atlanta, GA 30322, United States
    Neuroscience 249:139-53. 2013
  2. pmc Cardiac arrest and cardiopulmonary resuscitation dysregulates the hypothalamic-pituitary-adrenal axis
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30322, USA
    J Cereb Blood Flow Metab 29:1673-82. 2009
  3. doi request reprint The neurobiological toll of child abuse and neglect
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, USA
    Trauma Violence Abuse 10:389-410. 2009
  4. pmc Changes in the vascular area fraction of the hippocampus and amygdala are induced by prenatal dexamethasone and/or adult stress
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30322, USA
    J Cereb Blood Flow Metab 30:1100-4. 2010
  5. pmc Psychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge
    Christopher J Barnum
    Department of Physiology, School of Medicine, Emory University, 615 Michael Street, Atlanta, GA 30324, USA
    J Neuroinflammation 9:9. 2012
  6. pmc Exposure to repeated maternal aggression induces depressive-like behavior and increases startle in adult female rats
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States
    Behav Brain Res 227:270-5. 2012
  7. pmc Estradiol activates epithelial sodium channels in rat alveolar cells through the G protein-coupled estrogen receptor
    Megan M Greenlee
    Dept of Physiology, Emory Univ School of Medicine, 615 Michael St, Ste 655B, Atlanta, GA 30322
    Am J Physiol Lung Cell Mol Physiol 305:L878-89. 2013
  8. pmc Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, 101 Woodruff Circle, Suite 4000, Atlanta, GA 30322, United States
    Psychoneuroendocrinology 38:84-93. 2013
  9. ncbi request reprint 3-aminobenzamide prevents restraint-evoked immunocompromise
    Gretchen N Neigh
    Department of Psychology, Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 19:351-6. 2005
  10. ncbi request reprint Sex and lineage interact to predict behavioral effects of chronic adolescent stress in rats
    Constance S Harrell
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, USA
    Behav Brain Res 248:57-61. 2013

Collaborators

Detail Information

Publications20

  1. doi request reprint Translational reciprocity: bridging the gap between preclinical studies and clinical treatment of stress effects on the adolescent brain
    G N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, 101 Woodruff Circle, Suite 4000, Atlanta, GA 30322, United States
    Neuroscience 249:139-53. 2013
    ....
  2. pmc Cardiac arrest and cardiopulmonary resuscitation dysregulates the hypothalamic-pituitary-adrenal axis
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30322, USA
    J Cereb Blood Flow Metab 29:1673-82. 2009
    ..Therefore, sustained changes in activity of the HPA axis and the CRF system after CA/CPR may contribute to the postischemic increase in affective disorders...
  3. doi request reprint The neurobiological toll of child abuse and neglect
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, USA
    Trauma Violence Abuse 10:389-410. 2009
    ..Recognition of the biological consequences and transgenerational impact of violence and abuse has critical importance for both disease research and public health policy...
  4. pmc Changes in the vascular area fraction of the hippocampus and amygdala are induced by prenatal dexamethasone and/or adult stress
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia 30322, USA
    J Cereb Blood Flow Metab 30:1100-4. 2010
    ..These data indicate that in addition to the well-documented stress-induced changes in neurons and glia, cerebral vasculature is also altered by exposure to stressors...
  5. pmc Psychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge
    Christopher J Barnum
    Department of Physiology, School of Medicine, Emory University, 615 Michael Street, Atlanta, GA 30324, USA
    J Neuroinflammation 9:9. 2012
    ..However, long-term outcomes of chronic psychological stressors that elicit a neuroinflammatory response remain unknown...
  6. pmc Exposure to repeated maternal aggression induces depressive-like behavior and increases startle in adult female rats
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States
    Behav Brain Res 227:270-5. 2012
    ....
  7. pmc Estradiol activates epithelial sodium channels in rat alveolar cells through the G protein-coupled estrogen receptor
    Megan M Greenlee
    Dept of Physiology, Emory Univ School of Medicine, 615 Michael St, Ste 655B, Atlanta, GA 30322
    Am J Physiol Lung Cell Mol Physiol 305:L878-89. 2013
    ..The results presented herein implicate E2-mediated regulation of alveolar sodium channels in the sex differences observed in the pathogenesis of several pulmonary diseases. ..
  8. pmc Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, 101 Woodruff Circle, Suite 4000, Atlanta, GA 30322, United States
    Psychoneuroendocrinology 38:84-93. 2013
    ..This study provides new evidence for sex differences during development and adaptation of the glucocorticoid receptor chaperone system...
  9. ncbi request reprint 3-aminobenzamide prevents restraint-evoked immunocompromise
    Gretchen N Neigh
    Department of Psychology, Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 19:351-6. 2005
    ..These data suggest that PARP inhibitors may be useful to prevent compromised immune function in response to stressors...
  10. ncbi request reprint Sex and lineage interact to predict behavioral effects of chronic adolescent stress in rats
    Constance S Harrell
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, USA
    Behav Brain Res 248:57-61. 2013
    ..Collectively, these data indicate that selective breeding interacts with chronic stress exposure during adolescence to dictate behavioral outcomes...
  11. ncbi request reprint SSRI or CRF antagonism partially ameliorate depressive-like behavior after adolescent social defeat
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA
    Behav Brain Res 270:295-9. 2014
    ..These data suggest that CRF1 receptor antagonists may be a viable alternative for treatment of depressive behaviors in adolescents. ..
  12. ncbi request reprint Chronic stress modulates regional cerebral glucose transporter expression in an age-specific and sexually-dimorphic manner
    Sean D Kelly
    Department of Physiology, Emory University, Atlanta, GA 30322, United States
    Physiol Behav 126:39-49. 2014
    ..Given the importance of appropriate metabolic balance within the brain, further assessment of the functional implications of life stage and environmentally-induced changes in GLUTs are warranted. ..
  13. pmc Prenatal exposure to escitalopram and/or stress in rats produces limited effects on endocrine, behavioral, or gene expression measures in adult male rats
    Chase H Bourke
    Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA
    Neurotoxicol Teratol 39:100-9. 2013
    ..Study design should be carefully considered before implications for human health are ascribed to prenatal exposure to stress or antidepressant medication. ..
  14. pmc Not all depression is created equal: sex interacts with disease to precipitate depression
    Christina L Nemeth
    Emory University Department of Physiology, Atlanta, GA, USA
    Biol Sex Differ 4:8. 2013
    ....
  15. pmc Stress-induced sex differences: adaptations mediated by the glucocorticoid receptor
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA
    Horm Behav 62:210-8. 2012
    ..New considerations of glucocorticoid regulation through the co-chaperone complex in the brain will be vital to the development of treatment strategies for men and women afflicted by neuropsychiatric and somatic disorders...
  16. doi request reprint Microembolism infarcts lead to delayed changes in affective-like behaviors followed by spatial memory impairment
    Christina L Nemeth
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, United States
    Behav Brain Res 234:259-66. 2012
    ..Collectively, these data demonstrate that microembolism infarcts are sufficient to induce changes in affective-like behavior and these changes precede alterations in spatial memory...
  17. ncbi request reprint Reduced glucocorticoid receptors: consequence or cause of depression?
    Gretchen N Neigh
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 101 Woodruff Circle, Suite 4000 Atlanta, GA 30322, USA
    Trends Endocrinol Metab 17:124-5. 2006
    ..This model offers a novel system for the study of the pathophysiology that underlies depression-like behaviors. It also adds to the growing evidence that implicates glucocorticoid receptor dysfunction in depression...
  18. ncbi request reprint Microembolism induces anhedonia but no detectable changes in white matter integrity in aged rats
    Christina L Nemeth
    Department of Psychiatry and Behavioral Science, Emory University, Atlanta, Georgia, United States of America Department of Physiology, Emory University, Atlanta, Georgia, United States of America
    PLoS ONE 9:e96624. 2014
    ..Together, data suggest that behavioral deficits are not the result of damage to brain regions or white matter tracts, rather the activity of other systems may underlie functional disruption and recovery. ..
  19. pmc Estradiol stimulates an anti-translocation expression pattern of glucocorticoid co-regulators in a hippocampal cell model
    Sanjana A Malviya
    Department of Physiology, Emory University, Atlanta, GA, United States
    Physiol Behav 122:187-92. 2013
    ..The results presented here illustrate that E2 generates an anti-translocation pattern of GR co-regulators in hippocampal cells. ..
  20. pmc Behavioral effects of chronic adolescent stress are sustained and sexually dimorphic
    Chase H Bourke
    Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA 30322, USA
    Horm Behav 60:112-20. 2011
    ....