Hui Mao

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi request reprint Magnetic resonance imaging of activated proliferating rhesus macaque T cells labeled with superparamagnetic monocrystalline iron oxide nanoparticles
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Woodruff Memorial Building, Room 2335A, 1639 Pierce Drive, Atlanta, GA, USA
    J Acquir Immune Defic Syndr 35:9-21. 2004
  2. ncbi request reprint Diffusion tensor and functional magnetic resonance imaging of diffuse axonal injury and resulting language impairment
    Hui Mao
    Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Neuroimaging 17:292-4. 2007
  3. pmc Receptor-targeted nanoparticles for in vivo imaging of breast cancer
    Lily Yang
    Department of Surgery and Winship Cancer Institute, Emory University School of Medicine, C 4088, 1365 C Clifton Road NE, Atlanta, GA 30322, USA
    Clin Cancer Res 15:4722-32. 2009
  4. ncbi request reprint Changes of metabolite profile in kainic acid induced hippocampal injury in rats measured by HRMAS NMR
    Hui Mao
    Department of Radiology and Frederick Philips MR Research Center, Emory University School of Medicine, 1364 Clifton Road, Atlanta, Georgia 30322, USA
    Exp Brain Res 183:477-85. 2007
  5. pmc Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging
    Lily Yang
    Department of Surgery, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Small 5:235-43. 2009
  6. pmc Casein-coated iron oxide nanoparticles for high MRI contrast enhancement and efficient cell targeting
    Jing Huang
    Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia 30322, United States
    ACS Appl Mater Interfaces 5:4632-9. 2013
  7. pmc Biocompatible polysiloxane-containing diblock copolymer PEO-b-PgammaMPS for coating magnetic nanoparticles
    Hongwei Chen
    Department of Radiology, Center for Systems Imaging, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    ACS Appl Mater Interfaces 1:2134-40. 2009
  8. pmc T₁-weighted ultrashort echo time method for positive contrast imaging of magnetic nanoparticles and cancer cells bound with the targeted nanoparticles
    Longjiang Zhang
    Department of Radiology, Center for Systems Imaging, Emory University School of Medicine, Atlanta, Georgia, USA
    J Magn Reson Imaging 33:194-202. 2011
  9. pmc EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma
    Costas G Hadjipanayis
    Brain Tumor Nanotechnology Laboratory, Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 70:6303-12. 2010
  10. pmc PEGylation of protein-based MRI contrast agents improves relaxivities and biocompatibilities
    Shunyi Li
    Department of Chemistry and Biology, Georgia State University, Atlanta, GA 30303, USA
    J Inorg Biochem 107:111-8. 2012

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Magnetic resonance imaging of activated proliferating rhesus macaque T cells labeled with superparamagnetic monocrystalline iron oxide nanoparticles
    J Bruce Sundstrom
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Woodruff Memorial Building, Room 2335A, 1639 Pierce Drive, Atlanta, GA, USA
    J Acquir Immune Defic Syndr 35:9-21. 2004
    ..These results indicate that intracellular labeling with MION can be a useful technique for noninvasively monitoring trafficking patterns of adoptively transferred leukocyte subsets in real-time by MRI in nonhuman primate models of AIDS...
  2. ncbi request reprint Diffusion tensor and functional magnetic resonance imaging of diffuse axonal injury and resulting language impairment
    Hui Mao
    Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Neuroimaging 17:292-4. 2007
    ..The findings demonstrate the utility of DTI for identifying white matter changes secondary to traumatic brain injury (TBI)...
  3. pmc Receptor-targeted nanoparticles for in vivo imaging of breast cancer
    Lily Yang
    Department of Surgery and Winship Cancer Institute, Emory University School of Medicine, C 4088, 1365 C Clifton Road NE, Atlanta, GA 30322, USA
    Clin Cancer Res 15:4722-32. 2009
    ..Cell-surface receptor-targeted magnetic iron oxide nanoparticles provide molecular magnetic resonance imaging contrast agents for improving specificity of the detection of human cancer...
  4. ncbi request reprint Changes of metabolite profile in kainic acid induced hippocampal injury in rats measured by HRMAS NMR
    Hui Mao
    Department of Radiology and Frederick Philips MR Research Center, Emory University School of Medicine, 1364 Clifton Road, Atlanta, Georgia 30322, USA
    Exp Brain Res 183:477-85. 2007
    ..This study demonstrates that ex vivo HRMAS NMR is a useful tool for analyzing and quantifying changes of neurochemistry and cerebral metabolism in the intact brain...
  5. pmc Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging
    Lily Yang
    Department of Surgery, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Small 5:235-43. 2009
    ..Efficient internalization of ScFvEGFR nanoparticles into tumor cells after systemic delivery suggests that the EGFR-targeted nanoparticles can also be used for the targeted delivery of therapeutic agents...
  6. pmc Casein-coated iron oxide nanoparticles for high MRI contrast enhancement and efficient cell targeting
    Jing Huang
    Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia 30322, United States
    ACS Appl Mater Interfaces 5:4632-9. 2013
    ..These favorable properties suggest CNIOs as a class of biomarker targeted magnetic nanoparticles for MRI contrast enhancement and related biomedical applications...
  7. pmc Biocompatible polysiloxane-containing diblock copolymer PEO-b-PgammaMPS for coating magnetic nanoparticles
    Hongwei Chen
    Department of Radiology, Center for Systems Imaging, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    ACS Appl Mater Interfaces 1:2134-40. 2009
    ..Furthermore, a much lower level of intracellular uptake by macrophage cells was observed with polysiloxane containing diblock copolymers coated IONPs, suggesting the reduction of nonspecific cell uptakes and antibiofouling effect...
  8. pmc T₁-weighted ultrashort echo time method for positive contrast imaging of magnetic nanoparticles and cancer cells bound with the targeted nanoparticles
    Longjiang Zhang
    Department of Radiology, Center for Systems Imaging, Emory University School of Medicine, Atlanta, Georgia, USA
    J Magn Reson Imaging 33:194-202. 2011
    ....
  9. pmc EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma
    Costas G Hadjipanayis
    Brain Tumor Nanotechnology Laboratory, Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 70:6303-12. 2010
    ....
  10. pmc PEGylation of protein-based MRI contrast agents improves relaxivities and biocompatibilities
    Shunyi Li
    Department of Chemistry and Biology, Georgia State University, Atlanta, GA 30303, USA
    J Inorg Biochem 107:111-8. 2012
    ..Such improvement can be important to the animal imaging and pre-clinical research at high or ultra-high field where there is an urgent need for molecular imaging probes and optimized contrast agent...
  11. pmc Molecular imaging of pancreatic cancer in an animal model using targeted multifunctional nanoparticles
    Lily Yang
    Department of Surgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Gastroenterology 136:1514-25.e2. 2009
    ....
  12. pmc Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy
    Xiang Hong Peng
    Department of Medical Oncology Hematology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Int J Nanomedicine 3:311-21. 2008
    ..We review recent advances in the development of targeted IO nanoparticles for tumor imaging and therapy...
  13. pmc Theranostic nanoparticles with controlled release of gemcitabine for targeted therapy and MRI of pancreatic cancer
    Gee Young Lee
    Departments of Surgery, Emory University School of Medicine, Atlanta, Georgia 30322, United States
    ACS Nano 7:2078-89. 2013
    ....
  14. doi request reprint Blockade of glioma proliferation through allosteric inhibition of JAK2
    Kunyan He
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Sci Signal 6:ra55. 2013
    ....
  15. pmc Acridine yellow G blocks glioblastoma growth via dual inhibition of epidermal growth factor receptor and protein kinase C kinases
    Qi Qi
    Department of Pathology and Laboratory Medicine, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Biol Chem 287:6113-27. 2012
    ..Hence, combinatorial inhibition of EGFR and PKCs might provide proof of concept in developing therapeutic agents for treating malignant glioma and other human cancers...
  16. pmc Targeted delivery of siRNA-generating DNA nanocassettes using multifunctional nanoparticles
    Young Seok Cho
    Emory University School of Medicine, Atlanta, GA 30322, USA
    Small 9:1964-73. 2013
    ..The ability of expression of siRNAs from multiple nanocassettes conjugated to a single nanoparticle following receptor-mediated internalization should enhance the therapeutic effect of the siRNA-mediated cancer therapy...
  17. pmc Group independent component analysis and functional MRI examination of changes in language areas associated with brain tumors at different locations
    Liya Wang
    Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia, United States of America
    PLoS ONE 8:e59657. 2013
    ..This study investigates the effect of tumor location on alterations of language network by brain tumors at different locations using blood oxygenation level dependent (BOLD) fMRI and group independent component analysis (ICA)...
  18. doi request reprint A dual-modal magnetic nanoparticle probe for preoperative and intraoperative mapping of sentinel lymph nodes by magnetic resonance and near infrared fluorescence imaging
    Zhengyang Zhou
    Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA
    J Biomater Appl 28:100-11. 2013
    ....
  19. pmc Protein-based MRI contrast agents for molecular imaging of prostate cancer
    Lixia Wei
    Department of Chemistry and Biology, Georgia State University, Atlanta, GA 30302, USA
    Mol Imaging Biol 13:416-23. 2011
    ....
  20. pmc Reducing non-specific binding and uptake of nanoparticles and improving cell targeting with an antifouling PEO-b-PgammaMPS copolymer coating
    Hongwei Chen
    Department of Radiology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Biomaterials 31:5397-407. 2010
    ....
  21. doi request reprint Detection of "oncometabolite" 2-hydroxyglutarate by magnetic resonance analysis as a biomarker of IDH1/2 mutations in glioma
    Juliya Kalinina
    Department of Neurosurgery, Emory University, Atlanta, GA 30329, USA
    J Mol Med (Berl) 90:1161-71. 2012
    ..It further opens up the possibility of developing analogous non-invasive MR-based imaging and spectroscopy studies directly in humans in the neuro-oncology clinic...
  22. pmc Development of multifunctional nanoparticles for targeted drug delivery and noninvasive imaging of therapeutic effect
    Hari Krishna Sajja
    Department of Surgery and Winship Cancer Institute, Emory University School of Medicine, Room C 4088, 1365 C Clifton Road, Atlanta, GA 30322, USA
    Curr Drug Discov Technol 6:43-51. 2009
    ....
  23. pmc Adaptor protein complex-4 (AP-4) deficiency causes a novel autosomal recessive cerebral palsy syndrome with microcephaly and intellectual disability
    Andres Moreno-De-Luca
    Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, USA
    J Med Genet 48:141-4. 2011
    ..Hypoxic-ischaemic injury, long considered the most frequent causative factor, accounts for fewer than 10% of cases, whereas a growing body of evidence suggests that diverse genetic abnormalities likely play a major role...
  24. doi request reprint Re-examine tumor-induced alterations in hemodynamic responses of BOLD fMRI: implications in presurgical brain mapping
    Liya Wang
    Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia, USA
    Acta Radiol 53:802-11. 2012
    ..Blood oxygenation level dependent (BOLD) fMRI is used for presurgical functional mapping of brain tumor patients. Abnormal tumor blood supply may affect hemodynamic responses and BOLD fMRI signals...
  25. pmc Targeted delivery of cisplatin to lung cancer using ScFvEGFR-heparin-cisplatin nanoparticles
    Xiang Hong Peng
    Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia 30322, United States
    ACS Nano 5:9480-93. 2011
    ..The new EHDDP nanoparticle delivery system significantly enhanced antitumor activity of DDP without weight loss or damage to the kidney and spleen in nude mice bearing H292 cell tumors...
  26. pmc White matter hyperintensities and changes in white matter integrity in patients with Alzheimer's disease
    Liya Wang
    Department of Radiology, Emory University School of Medicine, 1364 Clifton Road, Atlanta, GA 30329, USA
    Neuroradiology 53:373-81. 2011
    ..This study investigated the relationship between WMHs and white matter changes in AD using diffusion tensor imaging (DTI) and the sensitivity of each DTI index in distinguishing AD with WMHs...
  27. pmc Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation
    Dan Yan
    Department of Radiation Oncology, Emory University School of Medicine, Winship Cancer Institute of Emory University, Atlanta, Georgia, United States of America
    PLoS ONE 5:e11397. 2010
    ..In this study, we tested the new hypothesis: identifying the miRNAs to target DNA DSB repair genes could be a new way for sensitizing tumors to ionizing radiation...
  28. pmc Improving the magnetic resonance imaging contrast and detection methods with engineered magnetic nanoparticles
    Jing Huang
    1 Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Theranostics 2:86-102. 2012
    ..Furthermore, MRI methods for imaging magnetic nanoparticles including several newly developed MRI approaches aiming at improving the detection and quantification of the engineered magnetic nanoparticles are described...
  29. ncbi request reprint Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging
    Matthew N Rhyner
    Department of Biomedical Engineering, Chemistry, Hematology and Oncology, and the Winship Cancer Institute, Emory University and Georgia Institute of Technology, Atlanta, GA 30322, USA
    Nanomedicine (Lond) 1:209-17. 2006
    ..g., anticancer) agents. In this review, recent advances in the development and applications of bioconjugated quantum dots and multifunctional nanoparticles for in vivo tumor imaging and targeting are discussed...
  30. pmc Rational design of protein-based MRI contrast agents
    Jenny J Yang
    Department of Chemistry, Center for Drug Design and Advanced Biotechnology, Georgia State University, Atlanta, Georgia 30303, USA
    J Am Chem Soc 130:9260-7. 2008
    ..With good biocompatibility and potential functionalities, these protein contrast agents may be used as molecular imaging probes to target disease markers, thereby extending applications of MRI...
  31. doi request reprint Adiabatic pulse preparation for imaging iron oxide nanoparticles
    Steven S Harris
    Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA
    Magn Reson Med 67:1133-7. 2012
    ..With its linearity with iron concentration and insensitivity to changes in the main magnetic field, the new method is well suited for quantitative iron oxide nanoparticle imaging...
  32. pmc Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism
    Balveen Kaur
    Department of Neurosurgery, Laboratory of Molecular Neuro Oncology, Winship Cancer Institute, Emory University, School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 69:1212-20. 2009
    ..These results advance the understanding of brain-specific angiogenic regulation, and suggest that Vstat120 has therapeutic potential in the treatment of brain tumors and other intracerebral vasculopathies...
  33. pmc Noninvasive monitoring of embryonic stem cells in vivo with MRI transgene reporter
    Jun Liu
    Neuroscience Program, Graduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, GA 30322, USA
    Tissue Eng Part C Methods 15:739-47. 2009
    ..The compatibility and functionality of ferritin as a reporter in mES cells opens up the possibility of using MRI for longitudinal noninvasive monitoring of ES cell-derived cell grafts at both molecular and cellular levels...
  34. ncbi request reprint Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model
    Seung Hee Kang
    Department of Hematology Oncology, Emory University, School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 66:11991-7. 2006
    ....
  35. ncbi request reprint Individual kidney blood flow measured with contrast-enhanced first-pass perfusion MR imaging
    Diego R Martin
    Department of Radiology, Emory University School of Medicine, Building A, AT 622, 1365 Clifton Rd NE, Atlanta, GA 30322, USA
    Radiology 246:241-8. 2008
    ..This study demonstrates feasibility of the gadolinium chelate perfusion method for RBF measurement and discusses potential applications. Supplemental material: http://radiology.rsnajnls.org/cgi/content/full/246/1/241/DC1...
  36. ncbi request reprint Altered brain activation during cognitive control in patients with moderate to severe traumatic brain injury
    Randall S Scheibel
    Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX 77030, USA
    Neurorehabil Neural Repair 21:36-45. 2007
    ..Persistent deficits in cognitive control have been documented following traumatic brain injury (TBI) but are inconsistently related to the presence and location of focal lesions...
  37. ncbi request reprint Detection of lactate in the human vitreous body using proton magnetic resonance spectroscopy
    Janet C Rucker
    Arch Ophthalmol 121:909-11. 2003