Research Topics
Genomes and GenesSpecies | Shishir K MaithelSummaryAffiliation: Emory University Country: USA Publications
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Publications
Importance of low preoperative platelet count in selecting patients for resection of hepatocellular carcinoma: a multi-institutional analysisShishir K Maithel
Division of Surgical Oncology, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Am Coll Surg 212:638-48; discussion 648-50. 2011..We hypothesized that low platelet count would be independently associated with increased perioperative morbidity and mortality after resection...
Differential expression of ERCC1 in pancreas adenocarcinoma: high tumor expression is associated with earlier recurrence and shortened survival after resectionShishir K Maithel
Department of Surgery, Division of Surgical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA
Ann Surg Oncol 18:2699-705. 2011..Increased tumor expression of excision repair cross-complementing gene-1 (ERCC1) is associated with decreased survival in patients with various cancers. Its effect in pancreatic adenocarcinoma (PAC) is not defined...
Laparoscopic distal pancreatectomy: trends and lessons learned through an 11-year experiencePeter J Kneuertz
Department of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA
J Am Coll Surg 215:167-76. 2012..We aimed to determine outcomes after LDP at a specialized center, analyze trends of patient selection and operative technique, and validate a complication risk score (CRS)...
An analysis of human equilibrative nucleoside transporter-1, ribonucleoside reductase subunit M1, ribonucleoside reductase subunit M2, and excision repair cross-complementing gene-1 expression in patients with resected pancreas adenocarcinoma: implicationSarah B Fisher
Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, USA
Cancer 119:445-53. 2013..To the authors's knowledge, their role in PAC is not defined...
Improving the clinical risk score: an analysis of molecular biomarkers in the era of modern chemotherapy for resectable hepatic colorectal cancer metastasesShishir K Maithel
Department of Surgery, Division of Surgical Oncology, Emory University, Atlanta, GA 10065, USA
Surgery 151:162-70. 2012..The prognostic relevance of variations in expression of specific tumor genes in colorectal cancer liver metastases (CRCLMs) in patients treated with resection and modern chemotherapy is not known...
Excision repair cross-complementing gene-1, ribonucleotide reductase subunit M1, ribonucleotide reductase subunit M2, and human equilibrative nucleoside transporter-1 expression and prognostic value in biliary tract malignancySarah B Fisher
Department of Surgery, Division of Surgical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, USA
Cancer 119:454-62. 2013..The differential expression and prognostic value of these biomarkers in biliary tract malignancy (BTM) is unknown...
Lymphovascular and perineural invasion as selection criteria for adjuvant therapy in intrahepatic cholangiocarcinoma: a multi-institution analysisSarah B Fisher
Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA
HPB (Oxford) 14:514-22. 2012..Some authors advocate treating patients with lymph node (LN) involvement; however, nodal assessment is often inadequate or not performed. This study aimed to identify surrogate criteria based on characteristics of the primary tumour...
Factors influencing readmission after pancreaticoduodenectomy: a multi-institutional study of 1302 patientsSyed A Ahmad
Central Pancreas Consortium, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Ann Surg 256:529-37. 2012..Despite this progress, early readmission rates after PD have been reported as high as 50%. Few reports have delineated factors associated with readmission after PD...
The prognostic importance of lymphovascular invasion in cholangiocarcinoma above the cystic duct: a new selection criterion for adjuvant therapy?Sameer H Patel
Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA
HPB (Oxford) 13:605-11. 2011..Pathological factors were recorded. The primary outcome assessed was overall survival (OS)...
Clinically relevant biomarkers to select patients for targeted inhibitor therapy after resection of hepatocellular carcinomaSameer H Patel
Department of Surgery, Division of Surgical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA
Ann Surg Oncol 18:3384-90. 2011..We hypothesized that overexpression of these proteins is associated with decreased survival after resection...
Preoperative CA 19-9 and the yield of staging laparoscopy in patients with radiographically resectable pancreatic adenocarcinomaShishir K Maithel
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ann Surg Oncol 15:3512-20. 2008..Factors associated with the likelihood of subradiographic unresectable disease have not been clearly defined...
Risk factors for pancreatic fistula after stapled gland transectionPreeti D Subhedar
Department of Surgery, Division of Surgical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA
Am Surg 77:965-70. 2011..Stapled pancreatic transection provides an acceptable PF rate after DP. Diabetes and staple size influence PF rates. In our experience, use of mesh staple line reinforcement did not reduce the incidence of PF after stapled transection...
Natural history of patients with subcentimeter pulmonary nodules undergoing hepatic resection for metastatic colorectal cancerShishir K Maithel
Department of Surgery, Division of Surgical Oncology, Emory University, Atlanta, GA, USA
J Am Coll Surg 210:31-8. 2010..CT imaging frequently detects subcentimeter pulmonary nodules (SPN) in patients undergoing resection of colorectal cancer liver metastases. Their clinical significance is unknown...
Effects of perioperative red blood cell transfusion on disease recurrence and survival after pancreaticoduodenectomy for ductal adenocarcinomaPeter J Kneuertz
Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA
Ann Surg Oncol 18:1327-34. 2011..We examined the effects of RBCT during and after pancreaticoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC) on disease recurrence and survival...
Ampullary region carcinomas: definition and site specific classification with delineation of four clinicopathologically and prognostically distinct subsets in an analysis of 249 casesVolkan Adsay
Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
Am J Surg Pathol 36:1592-608. 2012..In conclusion, ACs comprise 4 clinicopathologic subtypes that are prognostically distinct...
Chemotherapy-associated liver injury: impact on surgical management of colorectal cancer liver metastasesPeter J Kneuertz
Department of Surgery, Division of Surgical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA
Ann Surg Oncol 18:181-90. 2011..In this review, we provide an overview of the spectrum of chemotherapy-associated liver injury and discuss its relevance to perioperative management of patients undergoing hepatic resection of colorectal cancer liver metastases...
Epidural analgesia for pancreatoduodenectomy: a critical appraisalWande B Pratt
Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
J Gastrointest Surg 12:1207-20. 2008..However, there is no detailed analysis of its efficacy for pancreatic operations. This study compares clinical and economic outcomes after epidural and intravenous analgesia for pancreatoduodenectomy...
Quality assessment in high-acuity surgery: volume and mortality are not enoughCharles M Vollmer
Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Arch Surg 142:371-80. 2007....
Clinical and economic validation of the International Study Group of Pancreatic Fistula (ISGPF) classification schemeWande B Pratt
Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Ann Surg 245:443-51. 2007..The authors sought to validate the ISGPF classification scheme in a large cohort of patients following pancreaticoduodenectomy (PD) in a pancreaticobiliary surgical specialty unit...
Is it time to abandon routine operative drain use? A single institution assessment of 709 consecutive pancreaticoduodenectomiesVishes V Mehta
Division of Surgical Oncology, Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA
J Am Coll Surg 216:635-42; discussion 642-4. 2013..We reviewed our experience with PD for postoperative (secondary) drainage and postoperative pancreatic fistula (POPF) rates based on use of primary drains...
Technical aspects of performing transduodenal ampullectomyShishir K Maithel
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
J Gastrointest Surg 12:1582-5. 2008..Specific indications for performing this procedure remain controversial. In this report, we describe the technical details necessary for successfully completing an ampullectomy...
Adjuncts to liver surgery: is acute normovolemic hemodilution useful for major hepatic resections?Shishir K Maithel
Department of Surgery, Hepatopancreatobiliary Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue C 887, New York, NY 10065, USA
Adv Surg 43:259-68. 2009..However, given the relatively low transfusion rate overall, future efforts should be directed at preoperatively identifying patients most likely to benefit from ANH...
An update on randomized clinical trials in advanced and metastatic colorectal carcinomaShishir K Maithel
Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Surg Oncol Clin N Am 19:163-81. 2010....
Safety and efficacy of doxorubicin drug-eluting bead transarterial chemoembolization in patients with advanced hepatocellular carcinomaHasmukh J Prajapati
Interventional Radiology and Image Guided Medicine, Winship Cancer Institute, Emory University School of Medicine, 1364 Clifton Road NE, Suite AG 05, Atlanta, GA 30322, USA
J Vasc Interv Radiol 24:307-15. 2013..To investigate the safety and efficacy of transarterial chemoembolization using doxorubicin drug-eluting beads (DEBs) in patients with Barcelona Clinic Liver Cancer (BCLC) C stage hepatocellular carcinoma (HCC)...
Impact of regional lymph node evaluation in staging patients with periampullary tumorsShishir K Maithel
Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Stoneman 9, 330 Brookline Avenue, Boston, Massachusetts, 02215, USA
Ann Surg Oncol 14:202-10. 2007..We examined whether radiographical enlargement of either lymph node predicts tumor resectability, nodal metastasis, or patient survival...
Hepatic ablation for neuroendocrine tumor metastasesShishir K Maithel
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
J Surg Oncol 100:635-8. 2009..In particular, radiofrequency ablation has been utilized with good results and minimal morbidity for treating patients with advanced neuroendocrine disease...
1 or 2 cm margins of excision for T2 melanomas: do they impact recurrence or survival?Laura E Hudson
Division of Surgical Oncology, Department of Surgery, Emory University School of Medicine and the Winship Cancer Institute, Atlanta, Georgia, USA
Ann Surg Oncol 20:346-51. 2013..We hypothesized 1- or 2-cm margins would have similar local recurrence (LR) and overall survival (OS)...
Presentation and management of gastrointestinal stromal tumors of the duodenum: a multi-institutional analysisFabian M Johnston
Department of Surgery, The Johns Hopkins University, Baltimore, MD, USA
Ann Surg Oncol 19:3351-60. 2012..We evaluated surgical management and outcomes of patients with duodenal GISTs treated with pancreaticoduodenectomy (PD) versus local resection (LR) and defined factors associated with prognosis...
Natural orifice translumenal endoscopic surgery in humans: a reviewMichelle P Clark
Division of Digestive Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, GA 30322, USA
Minim Invasive Surg 2012:189296. 2012..A preponderance of published NOTES procedures were performed internationally. With further development, NOTES may make less invasive surgery available to a larger human population...
Postoperative pancreatic fistulas are not equivalent after proximal, distal, and central pancreatectomyWande Pratt
Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
J Gastrointest Surg 10:1264-78; discussion 1278-9. 2006..This translates into variable severity that guides management decisions, which ultimately dictate clinical outcomes and economic impact...
Posterior lumbar vein off the retrohepatic inferior vena cava: a novel anatomical variant with surgical implicationsAmmara Abbasi
Department of Urology, Emory University, Atlanta, Georgia, USA
J Urol 187:296-301. 2012..Since this represents an unrecognized source of hemorrhage, we investigated the frequency of a superior lumbar vein in cadaveric dissection...
A prospective randomized trial of acute normovolemic hemodilution compared to standard intraoperative management in patients undergoing major hepatic resectionWilliam R Jarnagin
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, C 887, New York, NY 10065, USA
Ann Surg 248:360-9. 2008....
