D W Loring

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi Testing the limits: cautions and concerns regarding the new Wechsler IQ and Memory scales
    David W Loring
    Department of Neurology, Emory University, 101 Woodruff Circle, Suite 6000, Atlanta, GA, USA
    Neurology 74:685-90. 2010
  2. ncbi Acute lorazepam effects on neurocognitive performance
    David W Loring
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Epilepsy Behav 25:329-33. 2012
  3. ncbi Diagnostic utility of Wada Memory Asymmetries: sensitivity, specificity, and likelihood ratio characterization
    David W Loring
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Neuropsychology 23:687-93. 2009
  4. ncbi Topiramate dose effects on cognition: a randomized double-blind study
    D W Loring
    Department of Neurology, Emory University, 101 Woodruff Circle, Suite 6000, Atlanta, GA 30322, USA
    Neurology 76:131-7. 2011
  5. ncbi History of neuropsychology through epilepsy eyes
    David W Loring
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Arch Clin Neuropsychol 25:259-73. 2010
  6. ncbi Common data elements in epilepsy research: development and implementation of the NINDS epilepsy CDE project
    David W Loring
    Department of Neurology, Emory University, Atlanta, Georgia, USA
    Epilepsia 52:1186-91. 2011
  7. ncbi Neuropsychological advocacy and epilepsy
    David W Loring
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Clin Neuropsychol 24:417-28. 2010
  8. ncbi Effects of fetal antiepileptic drug exposure: outcomes at age 4.5 years
    K J Meador
    Neurology and Pediatrics, Emory University, Atlanta, GA, USA
    Neurology 78:1207-14. 2012
  9. ncbi Differential cognitive effects of carbamazepine and gabapentin
    K J Meador
    Department of Neurology, Medical College of Georgia, Augusta 30912, USA
    Epilepsia 40:1279-85. 1999
  10. ncbi Cognitive and behavioral effects of lamotrigine and topiramate in healthy volunteers
    K J Meador
    Department of Neurology, Georgetown University, Washington, DC, USA
    Neurology 64:2108-14. 2005

Detail Information

Publications40

  1. ncbi Testing the limits: cautions and concerns regarding the new Wechsler IQ and Memory scales
    David W Loring
    Department of Neurology, Emory University, 101 Woodruff Circle, Suite 6000, Atlanta, GA, USA
    Neurology 74:685-90. 2010
    ....
  2. ncbi Acute lorazepam effects on neurocognitive performance
    David W Loring
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Epilepsy Behav 25:329-33. 2012
    ....
  3. ncbi Diagnostic utility of Wada Memory Asymmetries: sensitivity, specificity, and likelihood ratio characterization
    David W Loring
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Neuropsychology 23:687-93. 2009
    ..9%) obtained a difference score of -8. Multiple level LRs indicate impressive diagnostic sensitivity for certain WMA ranges, greatly increasing the probability of undergoing either left or right TL surgery depending on WMA magnitude...
  4. ncbi Topiramate dose effects on cognition: a randomized double-blind study
    D W Loring
    Department of Neurology, Emory University, 101 Woodruff Circle, Suite 6000, Atlanta, GA 30322, USA
    Neurology 76:131-7. 2011
    ..Topiramate (TPM), a broad-spectrum antiepileptic drug, has been associated with neuropsychological impairment in patients with epilepsy and in healthy volunteers...
  5. ncbi History of neuropsychology through epilepsy eyes
    David W Loring
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Arch Clin Neuropsychol 25:259-73. 2010
    ....
  6. ncbi Common data elements in epilepsy research: development and implementation of the NINDS epilepsy CDE project
    David W Loring
    Department of Neurology, Emory University, Atlanta, Georgia, USA
    Epilepsia 52:1186-91. 2011
    ..This article describes the NINDS CDE Initiative, the process used in developing Epilepsy CDEs, and the benefits of CDEs for the clinical investigator and NINDS...
  7. ncbi Neuropsychological advocacy and epilepsy
    David W Loring
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Clin Neuropsychol 24:417-28. 2010
    ..We also include a seizure action plan, which is designed to be both an educational tool for individuals with limited epilepsy knowledge, and a way to minimize stigma associated with an event should a seizure occur during school or work...
  8. ncbi Effects of fetal antiepileptic drug exposure: outcomes at age 4.5 years
    K J Meador
    Neurology and Pediatrics, Emory University, Atlanta, GA, USA
    Neurology 78:1207-14. 2012
    ..To examine outcomes at age 4.5 years and compare to earlier ages in children with fetal antiepileptic drug (AED) exposure...
  9. ncbi Differential cognitive effects of carbamazepine and gabapentin
    K J Meador
    Department of Neurology, Medical College of Georgia, Augusta 30912, USA
    Epilepsia 40:1279-85. 1999
    ..The cognitive effects of the newer antiepileptic drugs (AEDs) compared with the older standard AEDs are uncertain...
  10. ncbi Cognitive and behavioral effects of lamotrigine and topiramate in healthy volunteers
    K J Meador
    Department of Neurology, Georgetown University, Washington, DC, USA
    Neurology 64:2108-14. 2005
    ..The relative cognitive and behavioral effects of lamotrigine (LTG) and topiramate (TPM) are unclear...
  11. ncbi Effects of breastfeeding in children of women taking antiepileptic drugs
    K J Meador
    Department of Neurology, Emory University, Woodruff Memorial Research Building, 101 Woodruff Circle, Suite 6000, Atlanta, GA 30322, USA
    Neurology 75:1954-60. 2010
    ..Animal and human studies have demonstrated that some AEDs can adversely affect the immature brain. However, no investigation has examined effects of breastfeeding during AED therapy on subsequent cognitive abilities in children...
  12. ncbi Differential cognitive and behavioral effects of carbamazepine and lamotrigine
    K J Meador
    Department of Neurology, Medical College of Georgia, Augusta, 30912, USA
    Neurology 56:1177-82. 2001
    ..The relative cognitive and behavioral effects of lamotrigine compared with the older standard antiepileptic drugs (AED) are uncertain...
  13. ncbi Differential cognitive and behavioral effects of topiramate and valproate
    K J Meador
    Department of Neurology, Medical College of Georgia, Augusta, USA
    Neurology 60:1483-8. 2003
    ..Cognitive effects have been reported during topiramate (TPM) treatment, but effects relative to standard antiepileptic drugs are unclear...
  14. ncbi Neuropsychological and neurophysiologic effects of carbamazepine and levetiracetam
    K J Meador
    Department of Neurology, University of Florida, McKnight Brain Institute L3 100, 100 South Newell Drive, Gainesville, FL 32610, USA
    Neurology 69:2076-84. 2007
    ..The relative effects of levetiracetam (LEV) and carbamazepine (CBZ) on cognitive and neurophysiologic measures are uncertain...
  15. ncbi In utero antiepileptic drug exposure: fetal death and malformations
    K J Meador
    Department of Neurology, University of Florida, Gainesville 32610, USA
    Neurology 67:407-12. 2006
    ..Pregnancy outcomes following in utero exposure to antiepileptic drugs (AEDs) are uncertain, limiting an evidenced-based approach...
  16. ncbi Limb and hemispatial hypometria
    K J Meador
    Department of Neurology, Medical College of Georgia, Augusta 30912 3280, USA
    J Int Neuropsychol Soc 6:71-5. 2000
    ..No effect was found for direction of sensory input. The results suggest that the directional hypometria is predominantly produced by hemispatial output deficits...
  17. ncbi Time perception following unilateral amobarbital injection in patients with temporal lobe epilepsy
    D L Drane
    Medical College of Georgia, Department of Neurology, Gainesville, USA
    J Clin Exp Neuropsychol 21:385-96. 1999
    ..These findings are discussed in the context of the growing evidence for a right-hemispheric attentional network...
  18. ncbi Subjective preference for lamotrigine or topiramate in healthy volunteers: relationship to cognitive and behavioral functioning
    Mary Ann Werz
    Department of Neurology, University Hospitals of Cleveland and Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Epilepsy Behav 8:181-91. 2006
    ..Additionally, drug preference was related to effects of lamotrigine and topiramate on objective neuropsychological tests as well as self-perception on behavioral instruments...
  19. ncbi Relationship of extinction to perceptual thresholds for single stimuli
    K J Meador
    Section of Behavioral Neurology, Department of Neurology, Medical College of Georgia, Augusta 30912-3280, USA
    Neurology 56:1044-7. 2001
    ..Asymmetries in mask and target intensities (relative to single-stimulus perceptual thresholds) affect extinction in RBS patients less for left targets but more for right targets as compared with control subjects...
  20. ncbi Antiepileptic drug use in women of childbearing age
    Kimford J Meador
    Department of Neurology, Emory University, Woodruff Memorial Research Building, 101 Woodruff Circle, Suite 6000, Mail Stop 1930 001 1AN, Atlanta, GA 30322, USA
    Epilepsy Behav 15:339-43. 2009
    ..Except for the top two AED monotherapies, there were marked differences in other monotherapies and in polytherapies between U.S. and UK centers. Future investigations are needed to examine reasons for drug choice...
  21. ncbi Dimensions of the epilepsy foundation concerns index
    David W Loring
    Department of Neurology, University of Florida, Gainesville, FL, USA
    Epilepsy Behav 6:348-52. 2005
    ..We conclude that the Epilepsy Foundation Concerns Index is multidimensional, and using a global score based on all items may mask specific concerns that may be relevant when applied to individual patients...
  22. ncbi Prediction of verbal memory decline after epilepsy surgery in children: effectiveness of Wada memory asymmetries
    Gregory P Lee
    Department of Neurology, Medical College of Georgia, Augusta, Georgia 30912 3275, USA
    Epilepsia 46:97-103. 2005
    ..It is unknown, however, whether these Wada memory asymmetries apply to children who undergo focal cortical resection or to epilepsy surgery patients who undergo resection outside the temporal lobes...
  23. ncbi Neurocognitive effects of brivaracetam, levetiracetam, and lorazepam
    Kimford J Meador
    Department of Neurology, Emory University, Atlanta, Georgia 30322, USA
    Epilepsia 52:264-72. 2011
    ..Although BRV is an analog of levetiracetam (LEV), in addition to being an SV2A ligand, it also inhibits sodium channels in a voltage-dependent manner. The cognitive effects of BRV are uncertain...
  24. ncbi Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age
    Kimford J Meador
    Department of Neurology, Emory University, Atlanta, GA 30322, USA
    Brain 134:396-404. 2011
    ..Additional research is needed to confirm these findings, extend the study to other drugs, define the risks associated with drug treatment for seizures in the neonates, and understand the underlying mechanisms...
  25. ncbi Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs
    Kimford J Meador
    Department of Neurology, Emory University, Woodruff Memorial Research Bldg, 101 Woodruff Cir, Suite 6000, Atlanta, GA 30322, USA
    N Engl J Med 360:1597-605. 2009
    ....
  26. ncbi Pre-surgical evaluation for epilepsy surgery
    D W Loring
    Department of Neurology, Medical College of Georgia, Augusta, Georgia 30912 3275, USA
    Saudi Med J 21:609-16. 2000
    ....
  27. ncbi Victoria symptom validity test performance in non-litigating epilepsy surgery candidates
    David W Loring
    Department of Neurology, Georgetown University Medical Center, Washington, DC 20057, USA
    J Clin Exp Neuropsychol 27:610-7. 2005
    ....
  28. ncbi Neuropsychological and behavioral effects of antiepilepsy drugs
    David W Loring
    Department of Neurology, University of Florida, Gainesville, USA
    Neuropsychol Rev 17:413-25. 2007
    ..The present article serves to provide an overview of our current understanding regarding the risks of antiepilepsy drug use for both cognitive and behavioral side effects...
  29. ncbi Differential neuropsychological test sensitivity to left temporal lobe epilepsy
    David W Loring
    Department of Neurology, University of Florida, Gainesville, Florida 32610, USA
    J Int Neuropsychol Soc 14:394-400. 2008
    ....
  30. ncbi Visual confrontation naming following left anterior temporal lobectomy: a comparison of surgical approaches
    B P Hermann
    Department of Neurology, University of Wisconsin Madison, 53792 5132, USA
    Neuropsychology 13:3-9. 1999
    ..Across surgical approaches, the risk for decline in visual confrontation naming was associated with a later age of seizure onset and more extensive resection of lateral temporal neocortex...
  31. ncbi Structural versus functional prediction of memory change following anterior temporal lobectomy
    David W Loring
    Department of Neurology, Georgetown University Medical Center, Building D, Suite 207, 4000 Reservoir Road, NW, Washington, DC 22057, USA
    Epilepsy Behav 5:264-8. 2004
    ..In the present case, behavioral measures were superior to structural measures in predicting cognitive change following surgery...
  32. ncbi Cognitive side effects of antiepileptic drugs in children
    David W Loring
    Department of Neurology, Georgetown University Medical Center, Washington, DC, USA
    Neurology 62:872-7. 2004
    ....
  33. ncbi A test of the mechanisms of sensory extinction to simultaneous stimulation
    B M Kluger
    Department of Neurology, University of Florida College of Medicine, Box 100236, Gainesville, FL 32610-0236, USA
    Neurology 70:1644-5. 2008
  34. ncbi Gamma coherence and conscious perception
    K J Meador
    Department of Neurology, Medical College of Georgia, Augusta, USA
    Neurology 59:847-54. 2002
    ..In addition, controversy exists as to whether the primary sensory cortices are involved directly in the mechanisms of conscious perception or just in processes prior to conscious awareness...
  35. ncbi Victoria Symptom Validity Test performance in a heterogenous clinical sample
    David W Loring
    Department of Neurology, University of Florida, Gainesville, FL 2610 0236, USA
    Clin Neuropsychol 21:522-31. 2007
    ..These data suggest that intentional response distortion in patients referred for non-forensic neuropsychological evaluation is rare. Performances by specific diagnosis using different classification criteria are also presented...
  36. ncbi Sensitivity of the Halstead and Wechsler Test Batteries to brain damage: Evidence from Reitan's original validation sample
    David W Loring
    Department of Neurology, Center for Neuropsychological Studies, McKnight Brian Institute, University of Florida, Gainesville, FL 32610, USA
    Clin Neuropsychol 20:221-9. 2006
    ..6). We suggest that differences in the statistical properties of each battery (e.g., raw scores vs. standardized scores) likely contribute to classification characteristics including test sensitivity and specificity...
  37. ncbi Determinants of quality of life in epilepsy
    David W Loring
    Department of Neurology, University of Florida, Gainesville, FL 32610, USA
    Epilepsy Behav 5:976-80. 2004
    ..Although quality of life has multiple determinants, symptoms of depression and seizure worry are the most important factors affecting QOL in patients with intractable epilepsy...
  38. ncbi Lateralized changes in autonomic arousal during emotional processing in patients with unilateral temporal lobe seizure onset
    Gregory P Lee
    Department of Occupational Therapy, School of Allied Health, Department of Neurology, School of Medicine, Medical College of Georgia, Augusta, Georgia, USA
    Int J Neurosci 112:743-57. 2002
    ..Dysfunction of left mesial temporal lobe structures may result in autonomic hyperarousal and a release of the unrestrained negative emotional tendencies of the right hemisphere...
  39. ncbi Role of cerebral lateralization in control of immune processes in humans
    Kimford J Meador
    Department of Neurology, Georgetown University, Washington, DC 20007, USA
    Ann Neurol 55:840-4. 2004
    ..The findings demonstrate a differential role of the left and right cerebral hemispheres on immune functions in humans...
  40. ncbi Structured cueing on a semantic fluency task differentiates patients with temporal versus frontal lobe seizure onset
    Daniel L Drane
    Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA
    Epilepsy Behav 9:339-44. 2006
    ....