Philip L F Johnson

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age
    Philip L F Johnson
    Department of Biology, Emory University, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 109:21432-7. 2012
  2. pmc How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens?
    Philip L F Johnson
    Department of Biology, Emory University, Atlanta, GA, USA
    Proc Biol Sci 279:2777-85. 2012
  3. pmc Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections
    Philip L F Johnson
    Department of Biology, Emory University, Atlanta, Georgia, USA
    J Virol 85:5565-70. 2011
  4. pmc Mutation rate distribution inferred from coincident SNPs and coincident substitutions
    Philip L F Johnson
    Department of Biology, Emory University, Atlanta, Georgia, USA
    Genome Biol Evol 3:842-50. 2011
  5. pmc A population biological approach to understanding the maintenance and loss of the T-cell repertoire during aging
    Philip L F Johnson
    Biology, Emory University, Atlanta, GA
    Immunology 142:167-75. 2014

Detail Information

Publications5

  1. pmc Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age
    Philip L F Johnson
    Department of Biology, Emory University, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 109:21432-7. 2012
    ..g., by an increased division rate or decreased death rate), with the person as a whole incurring the long-term cost of a decreased ability to fight infections...
  2. pmc How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens?
    Philip L F Johnson
    Department of Biology, Emory University, Atlanta, GA, USA
    Proc Biol Sci 279:2777-85. 2012
    ....
  3. pmc Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections
    Philip L F Johnson
    Department of Biology, Emory University, Atlanta, Georgia, USA
    J Virol 85:5565-70. 2011
    ..These findings should be taken into account when developing vaccines against persistent infections...
  4. pmc Mutation rate distribution inferred from coincident SNPs and coincident substitutions
    Philip L F Johnson
    Department of Biology, Emory University, Atlanta, Georgia, USA
    Genome Biol Evol 3:842-50. 2011
    ..At least for primates, these quickly mutating sites are few enough that the infinite sites model in population genetics remains appropriate...
  5. pmc A population biological approach to understanding the maintenance and loss of the T-cell repertoire during aging
    Philip L F Johnson
    Biology, Emory University, Atlanta, GA
    Immunology 142:167-75. 2014
    ..We also discuss consequences for strategies to rejuvenate the immune repertoire in old age. ..