Shawn M Jobe

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis
    Shawn M Jobe
    Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA
    Blood 111:1257-65. 2008
  2. ncbi Mitochondrial calcium and reactive oxygen species regulate agonist-initiated platelet phosphatidylserine exposure
    Hyo Jung Choo
    Department of Pediatrics, Aflac Cancer Center and Blood Disorders Service, Emory University and Children s Healthcare of Atlanta, Atlanta, GA, USA
    Arterioscler Thromb Vasc Biol 32:2946-55. 2012
  3. ncbi Role of FcRgamma and factor XIIIA in coated platelet formation
    Shawn M Jobe
    Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Blood 106:4146-51. 2005
  4. ncbi Platelet biogenesis and functions require correct protein O-glycosylation
    Yingchun Wang
    Departments of Biochemistry and Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 109:16143-8. 2012

Research Grants

  1. The platelet mitochondrial permeability transition and thrombosis
    Shawn Jobe; Fiscal Year: 2009
  2. The platelet mitochondrial permeability transition and thrombosis
    Shawn M Jobe; Fiscal Year: 2010

Collaborators

Detail Information

Publications4

  1. ncbi Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis
    Shawn M Jobe
    Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA
    Blood 111:1257-65. 2008
    ..These results implicate CypD and the MPTP as critical regulators of platelet activation and suggest a novel CypD-dependent negative-feedback mechanism regulating arterial thrombosis...
  2. ncbi Mitochondrial calcium and reactive oxygen species regulate agonist-initiated platelet phosphatidylserine exposure
    Hyo Jung Choo
    Department of Pediatrics, Aflac Cancer Center and Blood Disorders Service, Emory University and Children s Healthcare of Atlanta, Atlanta, GA, USA
    Arterioscler Thromb Vasc Biol 32:2946-55. 2012
    ..To study the interactions of cytoplasmic calcium elevation, mitochondrial permeability transition pore (mPTP) formation, and reactive oxygen species formation in the regulation of phosphatidylserine (PS) exposure in platelets...
  3. ncbi Role of FcRgamma and factor XIIIA in coated platelet formation
    Shawn M Jobe
    Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Blood 106:4146-51. 2005
    ..We conclude that FcRgamma, but not factor XIIIA, is essential for formation of highly procoagulant coated platelets following dual stimulation with collagen and thrombin...
  4. ncbi Platelet biogenesis and functions require correct protein O-glycosylation
    Yingchun Wang
    Departments of Biochemistry and Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 109:16143-8. 2012
    ....

Research Grants2

  1. The platelet mitochondrial permeability transition and thrombosis
    Shawn Jobe; Fiscal Year: 2009
    ....
  2. The platelet mitochondrial permeability transition and thrombosis
    Shawn M Jobe; Fiscal Year: 2010
    ....