R L Huot

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi Negative affect in offspring of depressed mothers is predicted by infant cortisol levels at 6 months and maternal depression during pregnancy, but not postpartum
    R L Huot
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Ann N Y Acad Sci 1032:234-6. 2004
  2. ncbi Development of adult ethanol preference and anxiety as a consequence of neonatal maternal separation in Long Evans rats and reversal with antidepressant treatment
    R L Huot
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University, Suite 4000, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Psychopharmacology (Berl) 158:366-73. 2001
  3. ncbi Jugular vein catheterization for repeated blood sampling in the unrestrained conscious rat
    K V Thrivikraman
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, WMRB 4000, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Brain Res Brain Res Protoc 10:84-94. 2002
  4. ncbi Foster litters prevent hypothalamic-pituitary-adrenal axis sensitization mediated by neonatal maternal separation
    R L Huot
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Psychoneuroendocrinology 29:279-89. 2004
  5. ncbi Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans rats
    Rebecca L Huot
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Brain Res 950:52-63. 2002
  6. ncbi Differential neuroendocrine responses to chronic variable stress in adult Long Evans rats exposed to handling-maternal separation as neonates
    Charlotte O Ladd
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Ste 4105, Atlanta, GA 30322, USA
    Psychoneuroendocrinology 30:520-33. 2005
  7. ncbi Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation
    Charlotte O Ladd
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Biol Psychiatry 55:367-75. 2004
  8. ncbi Postnatal maternal separation elevates the expression of the postsynaptic protein kinase C substrate RC3, but not presynaptic GAP-43, in the developing rat hippocampus
    Robert K McNamara
    Molecular Neuropsychopharmacology Laboratory, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Dev Neurosci 24:485-94. 2002

Research Grants

  1. Maternal Depression, Child Temperament and Cortisol
    Rebecca Huot; Fiscal Year: 2004

Detail Information

Publications8

  1. ncbi Negative affect in offspring of depressed mothers is predicted by infant cortisol levels at 6 months and maternal depression during pregnancy, but not postpartum
    R L Huot
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Ann N Y Acad Sci 1032:234-6. 2004
    ..We conclude that the effects of maternal depression on behavioral problems and vulnerability to mental illness may be mediated by altered temperament and enhanced stress responsiveness...
  2. ncbi Development of adult ethanol preference and anxiety as a consequence of neonatal maternal separation in Long Evans rats and reversal with antidepressant treatment
    R L Huot
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University, Suite 4000, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Psychopharmacology (Berl) 158:366-73. 2001
    ..CONCLUSIONS: These observations suggest that this maternal separation paradigm is a good model to study the effects of early adverse experience on the development of alcohol preference and anxiety...
  3. ncbi Jugular vein catheterization for repeated blood sampling in the unrestrained conscious rat
    K V Thrivikraman
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, WMRB 4000, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Brain Res Brain Res Protoc 10:84-94. 2002
    ..Application of this technique to monitor temporal changes in plasma stress hormones during stressor paradigms as well as after behavioral and pharmacological challenges is discussed...
  4. ncbi Foster litters prevent hypothalamic-pituitary-adrenal axis sensitization mediated by neonatal maternal separation
    R L Huot
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Psychoneuroendocrinology 29:279-89. 2004
    ....
  5. ncbi Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans rats
    Rebecca L Huot
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Brain Res 950:52-63. 2002
    ..The resulting change in morphology may contribute to the subtle, but consistent learning deficit and overall stress hyper-responsive phenotype observed in these animals...
  6. ncbi Differential neuroendocrine responses to chronic variable stress in adult Long Evans rats exposed to handling-maternal separation as neonates
    Charlotte O Ladd
    Stress Neurobiology Laboratory, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Ste 4105, Atlanta, GA 30322, USA
    Psychoneuroendocrinology 30:520-33. 2005
    ..The data suggest that many effects of prolonged HMS are reversible in adulthood by CS, while the neuroendocrine adaptations imbued by brief HMS are sufficiently stable to restrain pituitary-adrenal stress responses even following CS...
  7. ncbi Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation
    Charlotte O Ladd
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Biol Psychiatry 55:367-75. 2004
    ....
  8. ncbi Postnatal maternal separation elevates the expression of the postsynaptic protein kinase C substrate RC3, but not presynaptic GAP-43, in the developing rat hippocampus
    Robert K McNamara
    Molecular Neuropsychopharmacology Laboratory, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Dev Neurosci 24:485-94. 2002
    ..Elevations in RC3 expression would be predicted to perturb calcium-calmodulin signaling that may, in turn, impair the formation and/or maintenance of mossy fiber-CA3 synapses during postnatal development...

Research Grants1

  1. Maternal Depression, Child Temperament and Cortisol
    Rebecca Huot; Fiscal Year: 2004
    ..In addition, since some data has already been collected on this population, it will be possible to look at some longitudinal changes in infants and children of depressed mothers. ..