Eric Hunter

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses
    Colleen S Kraft
    Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA
    Retrovirology 9:22. 2012
  2. pmc Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity
    Sushma J Bhakta
    Emory Vaccine Center at the Yerkes National Primate Research Center and Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia 30329, USA
    Retrovirology 8:37. 2011
  3. pmc Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways
    Rong Rong
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
    PLoS Pathog 5:e1000594. 2009
  4. pmc Large changes in the CRAC segment of gp41 of HIV do not destroy fusion activity if the segment interacts with cholesterol
    Sundaram A Vishwanathan
    Emory Vaccine Research Center, Yerkes, Emory University, 954 Gatewood Road, Atlanta, Georgia 30329, USA
    Biochemistry 47:11869-76. 2008
  5. pmc Prevalence of seroconversion symptoms and relationship to set-point viral load: findings from a subtype C epidemic, 1995-2009
    Patrick S Sullivan
    Emory University Rollins School of Public Health, Atlanta, Georgia 30322, USA
    AIDS 26:175-84. 2012
  6. pmc Role of donor genital tract HIV-1 diversity in the transmission bottleneck
    Debrah I Boeras
    Department of Pathology, Emory University, Atlanta, GA 30329, USA
    Proc Natl Acad Sci U S A 108:E1156-63. 2011
  7. pmc Truncation of the membrane-spanning domain of human immunodeficiency virus type 1 envelope glycoprotein defines elements required for fusion, incorporation, and infectivity
    Ling Yue
    Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA
    J Virol 83:11588-98. 2009
  8. pmc Donor and recipient envs from heterosexual human immunodeficiency virus subtype C transmission pairs require high receptor levels for entry
    Melissa Alexander
    Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, 954 Gatewood Rd, Atlanta, GA 30329, USA
    J Virol 84:4100-4. 2010
  9. pmc Role of the membrane-spanning domain of human immunodeficiency virus type 1 envelope glycoprotein in cell-cell fusion and virus infection
    Liang Shang
    Emory Vaccine Center, Department of Pathology and Laboratory Medicine, and Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA
    J Virol 82:5417-28. 2008
  10. pmc Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1
    Richard E Haaland
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, United States of America
    PLoS Pathog 5:e1000274. 2009

Collaborators

Detail Information

Publications23

  1. pmc Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses
    Colleen S Kraft
    Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA
    Retrovirology 9:22. 2012
    ..We have, therefore, investigated the incidence and viral origin of superinfection in these couples...
  2. pmc Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity
    Sushma J Bhakta
    Emory Vaccine Center at the Yerkes National Primate Research Center and Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia 30329, USA
    Retrovirology 8:37. 2011
    ..Additional mutants targeting individual motifs were then constructed...
  3. pmc Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways
    Rong Rong
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
    PLoS Pathog 5:e1000594. 2009
    ....
  4. pmc Large changes in the CRAC segment of gp41 of HIV do not destroy fusion activity if the segment interacts with cholesterol
    Sundaram A Vishwanathan
    Emory Vaccine Research Center, Yerkes, Emory University, 954 Gatewood Road, Atlanta, Georgia 30329, USA
    Biochemistry 47:11869-76. 2008
    ..The study demonstrates that drastic changes can be made in the LWYIK segment with the retention of a significant fraction of the fusogenic activity, as long as the mutant proteins interact with cholesterol...
  5. pmc Prevalence of seroconversion symptoms and relationship to set-point viral load: findings from a subtype C epidemic, 1995-2009
    Patrick S Sullivan
    Emory University Rollins School of Public Health, Atlanta, Georgia 30322, USA
    AIDS 26:175-84. 2012
    ..To describe symptoms, physical examination findings, and set-point viral load associated with acute HIV seroconversion in a heterosexual cohort of HIV-discordant couples in Zambia...
  6. pmc Role of donor genital tract HIV-1 diversity in the transmission bottleneck
    Debrah I Boeras
    Department of Pathology, Emory University, Atlanta, GA 30329, USA
    Proc Natl Acad Sci U S A 108:E1156-63. 2011
    ....
  7. pmc Truncation of the membrane-spanning domain of human immunodeficiency virus type 1 envelope glycoprotein defines elements required for fusion, incorporation, and infectivity
    Ling Yue
    Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA
    J Virol 83:11588-98. 2009
    ....
  8. pmc Donor and recipient envs from heterosexual human immunodeficiency virus subtype C transmission pairs require high receptor levels for entry
    Melissa Alexander
    Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, 954 Gatewood Rd, Atlanta, GA 30329, USA
    J Virol 84:4100-4. 2010
    ..Thus, HIV-1 transmission does not appear to select for viruses that can preferentially utilize low levels of entry receptors...
  9. pmc Role of the membrane-spanning domain of human immunodeficiency virus type 1 envelope glycoprotein in cell-cell fusion and virus infection
    Liang Shang
    Emory Vaccine Center, Department of Pathology and Laboratory Medicine, and Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA
    J Virol 82:5417-28. 2008
    ..These studies imply that the highly conserved core residues of the HIV Env MSD, in addition to serving as a membrane anchor, play an important role in mediating membrane fusion during viral entry...
  10. pmc Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1
    Richard E Haaland
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, United States of America
    PLoS Pathog 5:e1000274. 2009
    ....
  11. pmc Antibody responses against xenotropic murine leukemia virus-related virus envelope in a murine model
    Natalia Makarova
    Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America
    PLoS ONE 6:e18272. 2011
    ....
  12. pmc Importance of the membrane-perturbing properties of the membrane-proximal external region of human immunodeficiency virus type 1 gp41 to viral fusion
    Sundaram A Vishwanathan
    Department of Pathology and Laboratory Medicine, Emory Vaccine Center, and Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA
    J Virol 82:5118-26. 2008
    ..These data suggest that both structural (for Env incorporation) and functional (membrane disruption) constraints may contribute to the highly conserved nature of this region...
  13. pmc Indeterminate and discrepant rapid HIV test results in couples' HIV testing and counselling centres in Africa
    Debrah I Boeras
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
    J Int AIDS Soc 14:18. 2011
    ..We investigated the use of an algorithm using three serial rapid HIV tests in cohabiting couples to resolve unclear serostatuses...
  14. pmc Residues in the membrane-spanning domain core modulate conformation and fusogenicity of the HIV-1 envelope glycoprotein
    Liang Shang
    Yerkes National Primate Research Center, Department of Pathology and Laboratory Medicine, and Emory Vaccine Center, Emory University, Atlanta, GA 30329, USA
    Virology 404:158-67. 2010
    ..These changes could delay initiation of the conformational changes required in the fusion process...
  15. pmc Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress
    Anne M Fitzpatrick
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA
    J Allergy Clin Immunol 123:146-152.e8. 2009
    ..Severe asthma is characterized by persistent airway inflammation and increased formation of reactive oxygen species...
  16. pmc Basic residues in the Mason-Pfizer monkey virus gag matrix domain regulate intracellular trafficking and capsid-membrane interactions
    Elizabeth Stansell
    Department of Pathology and Emory Vaccine Center at Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia 30329, USA
    J Virol 81:8977-88. 2007
    ..All mutants that released virions exhibited near-wild-type infectivity in a single-round assay. Thus, basic amino acids in the M-PMV MA define both cellular location and efficiency of virus release...
  17. pmc Evaluation of cellular determinants required for in vitro xenotropic murine leukemia virus-related virus entry into human prostate cancer and noncancerous cells
    Sushma Bhosle
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA
    J Virol 84:6288-96. 2010
    ....
  18. pmc Identification of postentry restrictions to Mason-Pfizer monkey virus infection in New World monkey cells
    William E Diehl
    Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA
    J Virol 82:11140-51. 2008
    ..Our results demonstrate that TRIM5alpha specificity extends to betaretroviruses and suggest that New World monkeys have evolved additional mechanisms to restrict the infection of at least one primate betaretrovirus...
  19. ncbi request reprint Hydrophobic substitutions in the first residue of the CRAC segment of the gp41 protein of HIV
    Sundaram A Vishwanathan
    Emory Vaccine Research Center, Yerkes, Emory University, 954 Gatewood Rd, Atlanta, Georgia 30329, USA
    Biochemistry 47:124-30. 2008
    ....
  20. doi request reprint XMRV infection in patients with prostate cancer: novel serologic assay and correlation with PCR and FISH
    Rebecca S Arnold
    Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Urology 75:755-61. 2010
    ....
  21. ncbi request reprint Viral characteristics of transmitted HIV
    Cynthia A Derdeyn
    Department of Pathology and Laboratory Medicine, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA
    Curr Opin HIV AIDS 3:16-21. 2008
    ..A better understanding of the restrictions inflicted upon transmitting HIV-1 should therefore lead to improved biomedical interventions that have the potential to protect against HIV infection...
  22. pmc Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1
    Rong Rong
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, Atlanta, GA 30329, USA
    J Virol 81:5658-68. 2007
    ..These findings suggest that subtype C viruses utilize mutations in the alpha2 helix for efficient viral replication and immune avoidance...
  23. ncbi request reprint Real-time PCR quantitation of subtype C HIV DNA in a Zambian discordant couple cohort
    Roy W Johnson
    Emory Vaccine Center, Emory University, Atlanta, Georgia 30329, USA
    AIDS Res Hum Retroviruses 22:438-44. 2006
    ....