Ruo Pan Huang

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi Profiling of cytokine expression by biotin-labeled-based protein arrays
    Ying Lin
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA
    Proteomics 3:1750-7. 2003
  2. ncbi Enhanced protein profiling arrays with ELISA-based amplification for high-throughput molecular changes of tumor patients' plasma
    Ruochun Huang
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Clin Cancer Res 10:598-609. 2004
  3. ncbi An array of possibilities in cancer research using cytokine antibody arrays
    Ruo Pan Huang
    Emory University School of Medicine, Department of Gynecology and Obstetrics, Atlanta, GA 30322, USA
    Expert Rev Proteomics 4:299-308. 2007
  4. ncbi The promise of cytokine antibody arrays in the drug discovery process
    Ruo Pan Huang
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Expert Opin Ther Targets 9:601-15. 2005
  5. ncbi Protein arrays, an excellent tool in biomedical research
    Ruo Pan Huang
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Front Biosci 8:d559-76. 2003
  6. ncbi Cytokine antibody arrays: a promising tool to identify molecular targets for drug discovery
    Ruo Pan Huang
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, Woodruff Memorial Research Building Rm 4219, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Comb Chem High Throughput Screen 6:769-75. 2003
  7. ncbi Connexin 43 suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology
    Ruochun Huang
    Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Cancer Res 62:2806-12. 2002
  8. ncbi Concurrent down-regulation of Egr-1 and gelsolin in the majority of human breast cancer cells
    Jingbo Liu
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cancer Genomics Proteomics 4:377-85. 2007
  9. ncbi Proteomic identification of neurotrophins in the eutopic endometrium of women with endometriosis
    Aimee S Browne
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia, USA
    Fertil Steril 98:713-9. 2012
  10. ncbi Laminar shear inhibits tubule formation and migration of endothelial cells by an angiopoietin-2 dependent mechanism
    Sarah L Tressel
    Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA
    Arterioscler Thromb Vasc Biol 27:2150-6. 2007

Research Grants

  1. SUPPRESSION OF HUMAN GLIOBLASTOMA CELL GROWTH BY CX43
    Ruo Pan Huang; Fiscal Year: 2002
  2. Protein arrays to profile cytokine expression in ovaria*
    Ruo Pan Huang; Fiscal Year: 2005

Collaborators

  • Qian Shi
  • Jie Yu
  • Shiyong Li
  • Cheng C Wang
  • Biaoyang Lin
  • N Sidell
  • S W Han
  • Ying Lin
  • Shen-Ming Wang
  • Ya-Guang Liu
  • Aimee S Browne
  • Sarah L Tressel
  • Jingbo Liu
  • Thitikorn Wanichkul
  • Robert N Taylor
  • Antônio M C Francisco
  • Chen Yao
  • Weimin Yang
  • Nicholas Tomsen
  • Ya Guang Liu
  • Hanjoong Jo
  • Dongzi Yang
  • Craig Jordan
  • Lipai Chen
  • Li-Pai Chen
  • Zhen-Hai Lu
  • Henry Lisoukov
  • Xuan Cao
  • Sampath Parthasarathy
  • Jacob Gano
  • Nalini Santanam

Detail Information

Publications20

  1. ncbi Profiling of cytokine expression by biotin-labeled-based protein arrays
    Ying Lin
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA
    Proteomics 3:1750-7. 2003
    ..These results suggest that biotin-labeled-based antibody chip technology can provide a practical and powerful means of profiling hundreds or thousands of proteins for research and clinical purposes...
  2. ncbi Enhanced protein profiling arrays with ELISA-based amplification for high-throughput molecular changes of tumor patients' plasma
    Ruochun Huang
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Clin Cancer Res 10:598-609. 2004
    ....
  3. ncbi An array of possibilities in cancer research using cytokine antibody arrays
    Ruo Pan Huang
    Emory University School of Medicine, Department of Gynecology and Obstetrics, Atlanta, GA 30322, USA
    Expert Rev Proteomics 4:299-308. 2007
    ....
  4. ncbi The promise of cytokine antibody arrays in the drug discovery process
    Ruo Pan Huang
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Expert Opin Ther Targets 9:601-15. 2005
    ..Undoubtedly, the technology will continue to be improved and the application increased in the next several years...
  5. ncbi Protein arrays, an excellent tool in biomedical research
    Ruo Pan Huang
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Front Biosci 8:d559-76. 2003
    ..Such protein array technology holds great promise in biomedical research and clinical applications...
  6. ncbi Cytokine antibody arrays: a promising tool to identify molecular targets for drug discovery
    Ruo Pan Huang
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, Woodruff Memorial Research Building Rm 4219, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Comb Chem High Throughput Screen 6:769-75. 2003
    ..This novel technology opens up an expanding spectrum of applications in drug discovery, including target discovery, target validation, screening for lead compounds, compound optimization and clinical trials...
  7. ncbi Connexin 43 suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology
    Ruochun Huang
    Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Cancer Res 62:2806-12. 2002
    ..Our results suggested that MCP-1 is involved in the suppression of human glioblastoma cell growth by cx43...
  8. ncbi Concurrent down-regulation of Egr-1 and gelsolin in the majority of human breast cancer cells
    Jingbo Liu
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cancer Genomics Proteomics 4:377-85. 2007
    ..The aim of this study was to gain more evidence to support the role of Egr-1 in the suppression of cancer cell growth and to examine the potential correlation between Egr-1 and gelsolin...
  9. ncbi Proteomic identification of neurotrophins in the eutopic endometrium of women with endometriosis
    Aimee S Browne
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia, USA
    Fertil Steril 98:713-9. 2012
    ..To evaluate neurotrophin (NT) expression in the endometrium of women with and without endometriosis...
  10. ncbi Laminar shear inhibits tubule formation and migration of endothelial cells by an angiopoietin-2 dependent mechanism
    Sarah L Tressel
    Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA
    Arterioscler Thromb Vasc Biol 27:2150-6. 2007
    ..We hypothesized that LS inhibits EC migration and tubule formation, 2 functions important in angiogenesis, by inhibiting the secretion of proangiogenic factors...
  11. ncbi Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells
    Thitikorn Wanichkul
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Fertil Steril 79:763-9. 2003
    ..To determine whether peroxisome proliferator-activated receptor (PPAR)-gamma ligands can affect the expression of interleukin-6 (IL-6) and cytokines related to the pathogenesis of endometriosis...
  12. ncbi Profiling of human cytokines in healthy individuals with vitamin E supplementation by antibody array
    Ying Lin
    Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Room 429, Atlanta, GA 30322, USA
    Cancer Lett 187:17-24. 2002
    ..Our results suggested that MCP-1 may be one of the most important targets of antioxidant vitamin E. To the best of our knowledge, this is the first report describing the down-regulation of MCP-1 in vitamin E supplementation in vivo...
  13. ncbi [Effect of interleukin-8 in cell invasion and proliferation of human breast cancer]
    Ying Lin
    Center of Breast Disease, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
    Zhonghua Wai Ke Za Zhi 43:1541-4. 2005
    ..CONCLUSION: Interleukin-8 may be the key factor involved in human breast cancer progression and invasion, and play an important role in cell invasion of breast cancer...
  14. ncbi Enhanced protein profiling arrays for quantitative measurement of protein expression in multiple samples
    Ruochun Huang
    Department of Gynecology and Obstettrics, Emory University School of Medicine, Atlanta, GA, USA
    Methods Mol Med 114:209-21. 2005
    ..An account of the successful development and application of this enhanced protein profiling array technology is presented...
  15. ncbi Cytokine protein arrays
    Ruo-Pan Huang
    Department of Gynecology and Obstetrics, Emory University, Atlanta, GA, USA
    Methods Mol Biol 264:215-31. 2004
    ..An account of the successful development and application of cytokine protein arrays is presented...
  16. ncbi Detection of multiple cytokines by protein arrays from cell lysate and tissue lysate
    Ying Lin
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    Clin Chem Lab Med 41:139-45. 2003
    ..Future applications of this new approach include direct protein expression profiling, immunological disease diagnostics, and discovery of new biomarkers...
  17. ncbi [Angiogenic effect of interleukin-8 in breast cancer and its association with estrogen receptor]
    Ying Lin
    Center of Breast Disease, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
    Zhonghua Yi Xue Za Zhi 85:1419-23. 2005
    ..The IL-8 level in human breast cancer cells is negatively correlated with ER status. Exogenous ER may down-regulate the expression of IL-8 in breast cancer cell...
  18. ncbi Array-based multiplexed screening and quantitation of human cytokines and chemokines
    Cheng C Wang
    PerkinElmer Life Sciences, 800 Research Parkway, Meriden, Connecticut 06450, USA
    J Proteome Res 1:337-43. 2002
    ..Using this chip, we have examined cytokine expression in breast cancer cells and identified the chemokines associated with human cervical cancers...
  19. ncbi Analysis of gene expression in Egr-1 transfected human fibrosarcoma cells
    Ya-Guang Liu
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Surg Oncol 80:190-6. 2002
    ..The identification and further characterization of genes regulated by Egr-1 should provide valuable information to understand Egr-1 tumor suppressor action and the role of Egr-1 as a transcription factor in general...
  20. ncbi Identification of interleukin-8 as estrogen receptor-regulated factor involved in breast cancer invasion and angiogenesis by protein arrays
    Ying Lin
    Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    Int J Cancer 109:507-15. 2004
    ..Expression of exogenous ERalpha substantially inhibited IL-8 expression. Our findings raise intriguing questions regarding the role of IL-8 in the development and progression of human breast cancer in association with ER status...

Research Grants4

  1. SUPPRESSION OF HUMAN GLIOBLASTOMA CELL GROWTH BY CX43
    Ruo Pan Huang; Fiscal Year: 2002
    ..The elucidation of cx43 function involved in the tumor suppression with respect to activation of apoptosis eventually will provide a molecular basis for the development of anti-cancer compounds. ..
  2. Protein arrays to profile cytokine expression in ovaria*
    Ruo Pan Huang; Fiscal Year: 2005
    ..The data will be analyzed using statistics and bioinformatics tool and correlated with pathological and clinical data. The successful outcome of this grant may impact on the development of new biomarkers for patient-care management. ..