Research Topics
| C-L HsiehSummaryAffiliation: Emory University Country: USA Publications
| Collaborators
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Detail Information
Publications
A novel targeting modality to enhance adenoviral replication by vitamin D(3) in androgen-independent human prostate cancer cells and tumorsChia Ling Hsieh
Department of Urology, Molecular Urology and Therapeutics Program, Emory University School of Medicine, Atlanta, GA 30322, USA
Cancer Res 62:3084-92. 2002..Viral replication is highly enhanced by i.p. administration of vitamin D(3). Ultimately, enhancing Ad-hOC-E1 viral replication by vitamin D(3) may be used clinically to treat localized and osseous metastatic prostate cancer in men...- Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse modelChia Ling Hsieh
Molecular Urology and Therapeutic Program, Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Prostate 67:685-91. 2007.... - A luciferase transgenic mouse model: visualization of prostate development and its androgen responsiveness in live animalsC L Hsieh
Molecular Urology and Therapeutics Program, Department of Urology, Emory University School of Medicine, 1365B Clifton Road, NE Suite B4100, Atlanta, Georgia 30322, USA
J Mol Endocrinol 35:293-304. 2005..This model can be extended to detect the responsiveness of the prostate gland to therapy and used as a founder strain to visualize tumors in hosts with different genetic backgrounds... - Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cellsChia-Ling Hsieh
Molecular Urology and Therapeutics Program, Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Cancer Gene Ther 11:148-55. 2004..This principle can be applied to other clinical conditions of cancer growth where stroma contribute to the overall growth and survival potential of the cancer... - Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapyFengshuo Jin
Department of Urology, Molecular Urology and Therapeutic Program, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Cancer Gene Ther 12:257-67. 2005..Cotargeting tumor and tumor endothelium could be a promising gene therapy strategy for the treatment of both localized and metastatic human prostate cancer... - Stromal-epithelial interaction in prostate cancer progressionLeland W K Chung
Molecular Urology and Therapeutics Program, Department of Urology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
Clin Genitourin Cancer 5:162-70. 2006..By understanding the salient features of cancer-host interaction, novel therapeutics might be developed to target the cancer and its host in the treatment of lethal prostate cancer metastases... - Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging modelKristen Bisanz
Molecular Urology and Therapeutics Program, Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA
Mol Ther 12:634-43. 2005..This integrin-based gene therapy is particularly suitable for the treatment of prostate cancer bone metastasis... - Gene therapy for prostate cancer bone metastasis. Gene therapy targeting bone metastasisChia-Ling Hsieh
Molecular Urology and Therapeutics Program, Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
Cancer Treat Res 118:231-90. 2004 - beta2-microglobulin is a signaling and growth-promoting factor for human prostate cancer bone metastasisWen-Chin Huang
Molecular Urology and Therapeutics Program, Department of Urology and Winship Cancer Institute, Microchemical and Proteomics Facility, and Divison of Endocrinology and Metabolism and Lipids, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Cancer Res 66:9108-16. 2006..These results suggest that beta2M signaling is an attractive new therapeutic target for the treatment of lethal prostate cancer bone metastasis... - Tumor microenvironment promotes cancer progression, metastasis, and therapeutic resistanceShian-Ying Sung
Department of Urology, Emory University School of Medicine, Atlanta, GA, USA
Curr Probl Cancer 31:36-100. 2007 
In-vivo xenograft murine human uveal melanoma model develops hepatic micrometastasesHua Yang
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
Melanoma Res 18:95-103. 2008..These cells formed hepatic micrometastases in NU/NU mice after PC inoculation or tail vein injection, with significantly more micrometastases developing in the PC inoculation model than after tail vein injection...- IGF-I secretion by prostate carcinoma cells does not alter tumor-bone cell interactions in vitro or in vivoJanet Rubin
Department of Medicine, Emory University and VAMC, Decatur, Georgia
Prostate 66:789-800. 2006..Overexpression of IGF-I did not change either tumor progression or skeletal response. CONCLUSIONS: IGF-I is neither necessary nor sufficient for the osteoblastic response to PC metastases... - Identification of alpha-enolase as an autoantigen in lung cancer: its overexpression is associated with clinical outcomesGee-Chen Chang
Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taipei, Taiwan, Republic of China
Clin Cancer Res 12:5746-54. 2006..CONCLUSIONS: Our data strongly support a prognostic role of ENO1 in determining tumor malignancy of patients with NSCLC... - Amplification and overexpression of prosaposin in prostate cancerShahriar Koochekpour
Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
Genes Chromosomes Cancer 44:351-64. 2005....