C-L Hsieh

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi request reprint A novel targeting modality to enhance adenoviral replication by vitamin D(3) in androgen-independent human prostate cancer cells and tumors
    Chia Ling Hsieh
    Department of Urology, Molecular Urology and Therapeutics Program, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cancer Res 62:3084-92. 2002
  2. ncbi request reprint Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model
    Chia Ling Hsieh
    Molecular Urology and Therapeutic Program, Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 67:685-91. 2007
  3. ncbi request reprint A luciferase transgenic mouse model: visualization of prostate development and its androgen responsiveness in live animals
    C L Hsieh
    Molecular Urology and Therapeutics Program, Department of Urology, Emory University School of Medicine, 1365B Clifton Road, NE Suite B4100, Atlanta, Georgia 30322, USA
    J Mol Endocrinol 35:293-304. 2005
  4. ncbi request reprint Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cells
    Chia Ling Hsieh
    Molecular Urology and Therapeutics Program, Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Gene Ther 11:148-55. 2004
  5. ncbi request reprint Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapy
    Fengshuo Jin
    Department of Urology, Molecular Urology and Therapeutic Program, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Gene Ther 12:257-67. 2005
  6. ncbi request reprint Stromal-epithelial interaction in prostate cancer progression
    Leland W K Chung
    Molecular Urology and Therapeutics Program, Department of Urology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Clin Genitourin Cancer 5:162-70. 2006
  7. ncbi request reprint Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model
    Kristen Bisanz
    Molecular Urology and Therapeutics Program, Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Ther 12:634-43. 2005
  8. ncbi request reprint Gene therapy for prostate cancer bone metastasis. Gene therapy targeting bone metastasis
    Chia Ling Hsieh
    Molecular Urology and Therapeutics Program, Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cancer Treat Res 118:231-90. 2004
  9. ncbi request reprint beta2-microglobulin is a signaling and growth-promoting factor for human prostate cancer bone metastasis
    Wen Chin Huang
    Molecular Urology and Therapeutics Program, Department of Urology and Winship Cancer Institute, Microchemical and Proteomics Facility, and Divison of Endocrinology and Metabolism and Lipids, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 66:9108-16. 2006
  10. ncbi request reprint Tumor microenvironment promotes cancer progression, metastasis, and therapeutic resistance
    Shian Ying Sung
    Department of Urology, Emory University School of Medicine, Atlanta, GA, USA
    Curr Probl Cancer 31:36-100. 2007

Collaborators

Detail Information

Publications14

  1. ncbi request reprint A novel targeting modality to enhance adenoviral replication by vitamin D(3) in androgen-independent human prostate cancer cells and tumors
    Chia Ling Hsieh
    Department of Urology, Molecular Urology and Therapeutics Program, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cancer Res 62:3084-92. 2002
    ..Viral replication is highly enhanced by i.p. administration of vitamin D(3). Ultimately, enhancing Ad-hOC-E1 viral replication by vitamin D(3) may be used clinically to treat localized and osseous metastatic prostate cancer in men...
  2. ncbi request reprint Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model
    Chia Ling Hsieh
    Molecular Urology and Therapeutic Program, Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 67:685-91. 2007
    ....
  3. ncbi request reprint A luciferase transgenic mouse model: visualization of prostate development and its androgen responsiveness in live animals
    C L Hsieh
    Molecular Urology and Therapeutics Program, Department of Urology, Emory University School of Medicine, 1365B Clifton Road, NE Suite B4100, Atlanta, Georgia 30322, USA
    J Mol Endocrinol 35:293-304. 2005
    ..This model can be extended to detect the responsiveness of the prostate gland to therapy and used as a founder strain to visualize tumors in hosts with different genetic backgrounds...
  4. ncbi request reprint Cotargeting tumor and stroma in a novel chimeric tumor model involving the growth of both human prostate cancer and bone stromal cells
    Chia Ling Hsieh
    Molecular Urology and Therapeutics Program, Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Gene Ther 11:148-55. 2004
    ..This principle can be applied to other clinical conditions of cancer growth where stroma contribute to the overall growth and survival potential of the cancer...
  5. ncbi request reprint Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapy
    Fengshuo Jin
    Department of Urology, Molecular Urology and Therapeutic Program, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Gene Ther 12:257-67. 2005
    ..Cotargeting tumor and tumor endothelium could be a promising gene therapy strategy for the treatment of both localized and metastatic human prostate cancer...
  6. ncbi request reprint Stromal-epithelial interaction in prostate cancer progression
    Leland W K Chung
    Molecular Urology and Therapeutics Program, Department of Urology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Clin Genitourin Cancer 5:162-70. 2006
    ..By understanding the salient features of cancer-host interaction, novel therapeutics might be developed to target the cancer and its host in the treatment of lethal prostate cancer metastases...
  7. ncbi request reprint Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model
    Kristen Bisanz
    Molecular Urology and Therapeutics Program, Department of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Ther 12:634-43. 2005
    ..This integrin-based gene therapy is particularly suitable for the treatment of prostate cancer bone metastasis...
  8. ncbi request reprint Gene therapy for prostate cancer bone metastasis. Gene therapy targeting bone metastasis
    Chia Ling Hsieh
    Molecular Urology and Therapeutics Program, Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cancer Treat Res 118:231-90. 2004
  9. ncbi request reprint beta2-microglobulin is a signaling and growth-promoting factor for human prostate cancer bone metastasis
    Wen Chin Huang
    Molecular Urology and Therapeutics Program, Department of Urology and Winship Cancer Institute, Microchemical and Proteomics Facility, and Divison of Endocrinology and Metabolism and Lipids, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 66:9108-16. 2006
    ..These results suggest that beta2M signaling is an attractive new therapeutic target for the treatment of lethal prostate cancer bone metastasis...
  10. ncbi request reprint Tumor microenvironment promotes cancer progression, metastasis, and therapeutic resistance
    Shian Ying Sung
    Department of Urology, Emory University School of Medicine, Atlanta, GA, USA
    Curr Probl Cancer 31:36-100. 2007
  11. pmc In-vivo xenograft murine human uveal melanoma model develops hepatic micrometastases
    Hua Yang
    Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA
    Melanoma Res 18:95-103. 2008
    ..These cells formed hepatic micrometastases in NU/NU mice after PC inoculation or tail vein injection, with significantly more micrometastases developing in the PC inoculation model than after tail vein injection...
  12. ncbi request reprint IGF-I secretion by prostate carcinoma cells does not alter tumor-bone cell interactions in vitro or in vivo
    Janet Rubin
    Department of Medicine, Emory University and VAMC, Decatur, Georgia
    Prostate 66:789-800. 2006
    ..IGF-I is an important growth and differentiative factor for osteoblasts and may have a role in defining prostate cancer risk and skeletal metastases...
  13. ncbi request reprint Identification of alpha-enolase as an autoantigen in lung cancer: its overexpression is associated with clinical outcomes
    Gee Chen Chang
    Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taipei, Taiwan, Republic of China
    Clin Cancer Res 12:5746-54. 2006
    ..In this study, we intended to identify more TAAs in pleural effusion-derived tumor cells...
  14. ncbi request reprint Amplification and overexpression of prosaposin in prostate cancer
    Shahriar Koochekpour
    Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Genes Chromosomes Cancer 44:351-64. 2005
    ....