Larry A Greenbaum
Affiliation: Emory University
- Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndromeLarry A Greenbaum
Emory University and Children s Healthcare of Atlanta, Atlanta, Georgia, USA Electronic address
Kidney Int 89:701-11. 2016..Thus, our findings establish the efficacy and safety of eculizumab for pediatric patients with aHUS and are consistent with proposed immediate eculizumab initiation following diagnosis in children. ..
- Gaining the PROMIS perspective from children with nephrotic syndrome: a Midwest pediatric nephrology consortium studyDebbie S Gipson
Division of Nephrology, Department of Pediatrics and Communicable Diseases, C S Mott Children s Hospital, University of Michigan, 1500 E Medical Center Drive, SPC5297, Ann Arbor, MI 48109 5297, USA
Health Qual Life Outcomes 11:30. 2013..Successful measurement of patient reported outcomes will contribute to our understanding of the impact of NS on children and adolescents...
- Current advances in chronic kidney disease in children: growth, cardiovascular, and neurocognitive risk factorsLarry A Greenbaum
Division of Pediatric Nephrology, Department of Pediatrics, Emory University, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA
Semin Nephrol 29:425-34. 2009..Other early cardiovascular complications in children with CKD include left ventricular hypertrophy, cardiac dysfunction, and vascular calcifications...
- The association between abnormal birth history and growth in children with CKDLarry A Greenbaum
Division of Pediatric Nephrology, Emory University, 2015 Uppergate Drive, NE, Atlanta, GA 30322, USA
Clin J Am Soc Nephrol 6:14-21. 2011....
- Association between clinical risk factors and progression of chronic kidney disease in childrenAmy O Staples
Department of Pediatrics, University of New Mexico, Albuquerque, NM 87131, USA
Clin J Am Soc Nephrol 5:2172-9. 2010..There is a need to identify treatments to slow the progression of CKD, yet there are limited data regarding clinical risk factors that may be suitable targets to slow progression...
- Intravenous paricalcitol for treatment of secondary hyperparathyroidism in children on hemodialysisLarry A Greenbaum
Emory University and Children s Healthcare of Atlanta, GA 30322, USA
Am J Kidney Dis 49:814-23. 2007..Paricalcitol, a selective vitamin D receptor activator, causes less sustained hypercalcemia and increase in Ca x P product than calcitriol and has been used effectively in adult hemodialysis patients...
- Prevalence of sleep disturbances in children and adolescents with chronic kidney diseaseIra D Davis
Department of Pediatrics, Rainbow Babies and Children s Hospital Case Western Reserve University, Cleveland, OH, USA
Pediatr Nephrol 27:451-9. 2012..We conclude that sleep disturbances are common throughout the spectrum of chronic kidney disease in children and adolescents and are associated with diminished health-related quality of life scores...
- Obstacles to the prescribing of growth hormone in children with chronic kidney diseaseLarry A Greenbaum
Department of Pediatrics, Division of Pediatric Nephrology, Emory University and Children s Healthcare of Atlanta, 2015 Uppergate Drive, NE, Atlanta, GA, 30322, USA
Pediatr Nephrol 23:1531-5. 2008..The fact that more than 50% of short children with CKD did not receive rhGH is secondary to multiple factors, many of which may be amenable to intervention efforts...
- Anemia and risk of hospitalization in pediatric chronic kidney diseaseAmy O Staples
Division of Pediatric Nephrology, University of New Mexico, Albuquerque, NM 87131, USA
Clin J Am Soc Nephrol 4:48-56. 2009..Additionally, the associated morbidity of anemia in the pediatric CKD population has not been elucidated...
- Prevalence of clinical rejection after surveillance biopsies in pediatric renal transplants: does early subclinical rejection predispose to subsequent rejection episodes?Leonard C Hymes
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
Pediatr Transplant 13:823-6. 2009..Renal function and graft survival at 30 months also were no different between patients with SCR and those with normal SB. Early-SCR, when treated with rejection protocols, is not a prognostic indicator for subsequent CR episodes...
- Tacrolimus withdrawal and conversion to sirolimus at three months post-pediatric renal transplantationLeonard C Hymes
Department of Pediatrics, Emory University School of Medicine and Children s Healthcare of Atlanta, Atlanta, GA, USA
Pediatr Transplant 12:773-7. 2008..All recipients received basiliximab induction and TAC, MMF, and prednisone. Patients without acute rejection by surveillance biopsy at three months were eligible for SRL conversion...
- Renal dysplasia and MRI: a clinician's perspectiveLarry A Greenbaum
Division of Pediatric Nephrology, Children s Healthcare of Atlanta, Emory University, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA
Pediatr Radiol 38:S70-5. 2008..The emphasis is on the important clinical issues, and the potential of MRI as a methodology for providing clinically useful information not otherwise available from other imaging modalities...
- Vesicoureteral refluxLarry A Greenbaum
Division of Pediatric Nephrology, Emory University School of Medicine, Children s Healthcare of Atlanta, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA
Pediatr Clin North Am 53:413-27, vi. 2006..New insights into pathogenesis and new surgical techniques are changing the approach to the management of this disorder...
- Restless legs syndrome in children with chronic kidney diseaseSandeep K Riar
Division of Pediatric Nephrology, University of Kansas Medical Center, Kansas City, KS, USA
Pediatr Nephrol 28:773-95. 2013..There is limited information on RLS in children with CKD. Failure to account for conditions that might mimic RLS can lead to overdiagnosis of this syndrome...
- Effect of intensified diet education on serum phosphorus and knowledge of pediatric peritoneal dialysis patientsEmily L Abercrombie
Children s Healthcare of Atlanta, Atlanta, GA, USA
J Ren Nutr 20:193-8. 2010..To investigate the effect of intensive diet education on the knowledge and serum phosphorus levels of pediatric peritoneal dialysis (PD) patients and their parents...
- Treatment outcome of late steroid-resistant nephrotic syndrome: a study by the Midwest Pediatric Nephrology ConsortiumCaroline Straatmann
Department of Pediatrics, Louisiana State University Health Sciences Center, 200 Henry Clay Avenue, New Orleans, LA 70118, USA
Pediatr Nephrol 28:1235-41. 2013..These patients with late steroid resistance (LSR) are often treated with immunosuppressant medications, but the effect of these additional drugs on the long-term prognosis of LSR is still unknown...
- Kidney transplantation in children with decreased left ventricular systolic function: a Midwest Pediatric Nephrology Consortium studySandeep K Riar
Division of Pediatric Nephrology, University of Kansas Medical Center, Kansas City, KS, USA
Pediatr Nephrol 30:1343-8. 2015..In some cases, combined heart-kidney transplant may be considered or kidney transplant delayed until cardiac function improves. It is unknown whether these patients are at increased risk for poor outcomes after kidney transplantation...
- Delay in diagnosis in poststreptococcal glomerulonephritisPriya J Pais
Department of Pediatrics, Medical College of Wisconsin and Children s Research Institute of Children s Hospital of Wisconsin, Milwaukee, WI, USA
J Pediatr 153:560-4. 2008..To determine the frequency and risk factors for diagnostic delays in children with poststreptococcal glomerulonephritis (PSGN)...
- Rationale for growth hormone therapy in children with chronic kidney diseaseLarry A Greenbaum
Medical College of Wisconsin, Department of Pediatrics, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
Adv Chronic Kidney Dis 11:377-86. 2004..Administration of recombinant human growth hormone can overcome this problem, allowing catch-up growth and achievement of normal or improved adult height...
- Intravenous calcitriol for treatment of hyperparathyroidism in children on hemodialysisLarry A Greenbaum
Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
Pediatr Nephrol 20:622-30. 2005..This study demonstrates that i.v. calcitriol, at initial doses of 0.5-1.5 microg, effectively reduces PTH levels in pediatric HD patients and that patients should be closely monitored for hyperphosphatemia and elevated Ca x P product...
- Risk factors for early peritoneal dialysis catheter failure in childrenRandolph K Cribbs
Division of Pediatric Surgery, Department of Surgery, Emory University, Atlanta, GA 30322, USA
J Pediatr Surg 45:585-9. 2010..Operative technique, catheter selection, and patient variables (eg, age or prior surgical history) may influence catheter lifespan...
- Nephrotic syndrome after conversion to alternate day steroids in two children with a history of recurrent FSGSCoral D Hanevold
Department of Pediatrics, Medical College of Georgia, Augusta, GA 30912 3795, USA
Pediatr Transplant 7:395-9. 2003..Nephrotic syndrome reappeared years later when the patients were converted from daily to alternate day prednisone. In children with a history of FSGS, caution is necessary when altering the dosing schedule of prednisone...
- Follow-up urine cultures and fever in children with urinary tract infectionMelissa L Currie
Department of Pediatrics, Medical College of Wisconsin, Milwaukee 53226, USA
Arch Pediatr Adolesc Med 157:1237-40. 2003..The utility of repeat urine cultures and clinical significance of fever at 48 hours is unclear...