Research Topics
Species | A A GalSummaryAffiliation: Emory University Country: USA Publications
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Detail Information
Publications
Neuroendocrine lung tumors: grade correlates with proliferation but not angiogenesisZ K Arbiser
Department of Pathology, Southern Regional Medical Center (ZKA, Riverdale, Georgia, USA
Mod Pathol 14:1195-9. 2001..The association of increased proliferation and tumor type may prove to be clinically useful and shed light on the role of sequential oncogenic alterations in NLT...
Primary solitary endobronchial plasmacytomaEvgeny Edelstein
Department of Pathology, Meir Hospital, Saphir Medical Center, Kfar Saba, Israel
Ann Thorac Surg 78:1448-9. 2004..We report a case of a middle-age man who underwent endoscopic debulking followed by laser ablation for a pulmonary plasmacytoma, which showed a prominent endobronchial location with clinical and histopathologic verification...
The 100-year anniversary of the description of the frozen section procedureAnthony A Gal
Department of Pathology and Laboratory Medicine, Emory University Hospital, Room H171, 1364 Clifton Rd NE, Atlanta, GA 30322, USA
JAMA 294:3135-7. 2005
In search of the origins of modern surgical pathologyA A Gal
Deparment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Adv Anat Pathol 8:1-13. 2001..This historical review will trace the advances in microscopy, histochemistry, and surgery in the later half of the 19th century and early 20th century that led to the development of modern surgical pathology...
Antineutrophil cytoplasmic autoantibody in the absence of Wegener's granulomatosis or microscopic polyangiitis: implications for the surgical pathologistAnthony A Gal
Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
Mod Pathol 15:197-204. 2002..ANCA positivity alone, in the absence of appropriate clinical or pathologic findings, should not be used to substantiate a diagnosis of WG or MPA...
Granulomatous Pneumocystis carinii pneumonia complicating hematopoietic cell transplantationAnthony A Gal
Pathol Res Pract 198:553-8; discussion 559-61. 2002..Awareness of this unusual granulomatous tissue response to P. carinii and initiation of specific treatment can lead to successful resolution of this potentially lethal infection...
Neuroendocrine tumors of the thymus: a clinicopathological and prognostic studyA A Gal
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Ann Thorac Surg 72:1179-82. 2001..This study provides a useful clinicopathological classification and determines the relevance of specific prognostic factors...
p53, cellular proliferation, and apoptosis-related factors in thymic neuroendocrine tumorsAnthony A Gal
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Mod Pathol 17:33-9. 2004..05). Our study shows that p53 expression and certain apoptosis markers correlate with survival. The expression of these markers may account for differences in biological behavior...
Cytopathology of pulmonary alveolar proteinosis complicating lung transplantationAnthony A Gal
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Heart Lung Transplant 23:135-8. 2004..Although uncommon, pulmonary alveolar proteinosis can be diagnosed readily in BALF by its distinctive cytopathologic features and should be considered in the differential diagnosis of pulmonary disease in lung transplant recipients...
Use and abuse of lung biopsyAnthony A Gal
Department of Pathology and Laboratory Medicine, Atlanta, Georgia 30322, USA
Adv Anat Pathol 12:195-202. 2005..This review hopes to inform the reader of the indications and limitations of the lung biopsy...
The centennial anniversary of the frozen section technique at the Mayo ClinicAnthony A Gal
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Arch Pathol Lab Med 129:1532-5. 2005..Wilson, MD, at the Mayo Clinic in 1905 heralded the beginning of a new era in intraoperative diagnosis. This historical review traces the circumstances that led to this landmark publication 100 years ago...
The pathology of sarcoidosisAnthony A Gal
Department of Pathology and Laboratory Medicine, Emory University School of Medicine and Hospital, Atlanta, Georgia 30322, USA
Curr Opin Pulm Med 8:445-51. 2002..The clinician and pathologist should be aware of the diverse pathologic appearances of sarcoidosis...
Cumulative exposure to CD8+ granzyme Bhi T cells is associated with reduced lung function early after lung transplantationA Mohammed
Emory Transplant Center, Emory University School of Medicine, Atlanta, Georgia, USA
Transplant Proc 43:3892-8. 2011..These findings suggest that CD8+ T-cell-driven factors are responsible for early improvements in lung function after transplantation...
Predictors of outcome in thymectomy for myasthenia gravisJ M Budde
Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Ann Thorac Surg 72:197-202. 2001..Sex did not significantly correlate in the multivariate model. CONCLUSIONS: Sex, age, and thymic pathology are potential predictors of outcome in thymectomy for MG, and may shape treatment decisions and target higher-risk patients...
Flow and image cytometry in thymic neoplasia: correlation with clinical outcomeM B Kenny-Moynihan
Department of Pathology and Laboratory Medicine, Rollins School of Public Health, Robert W. Woodruff Health Sciences Center, Emory University, Atlanta, Georgia 30322, USA
Anal Quant Cytol Histol 23:313-20. 2001..While these findings are encouraging, larger numbers of cases will be needed to define the role of FCM and ICM in predicting outcome in thymic tumors...
Prognostic factors for hospital mortality and ICU admission in patients with ANCA-related pulmonary vasculitisFernando Holguin
Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Am J Med Sci 336:321-6. 2008..The objective of this study was to evaluate the factors predictive of 28-day mortality and admission to Intensive Care Unit (ICU) in patients with ANCA-related pulmonary vasculitis...
Thoracic presentations of posttransplant lymphoproliferative disordersMichael E Halkos
Cardiothoracic Research Laboratory, Division of Cardiothoracic Surgery, 550 Peachtree Street NE, Atlanta, GA 30308 2225, USA
Chest 126:2013-20. 2004..Posttransplant lymphoproliferative disorders (PTLDs) are rare complications following transplantation. Although organ-specific cases have been reported, primary presentation in the thoracic cavity has not been fully characterized...
Efficacy of oral ribavirin in lung transplant patients with respiratory syncytial virus lower respiratory tract infectionAndres Pelaez
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Heart Lung Transplant 28:67-71. 2009..Currently, the most widely used therapy for RSV is inhaled ribavirin. However, this therapy is costly and cumbersome. We investigated the utility of using oral ribavirin for the treatment of RSV infection after LTx...
Role of thoracic surgeons in the diagnosis of idiopathic interstitial lung diseaseMichael E Halkos
Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
Ann Thorac Surg 79:2172-9. 2005..In this article, we review the salient clinical, radiologic, and pathologic features of these unique disorders as well as the updated classification scheme. We also discuss the current methods, approaches, and indications for biopsy...
Interpretation of tissue artifacts in transbronchial lung biopsy specimensDianne M Kendall
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Ann Diagn Pathol 7:20-4. 2003..Various artifacts in transbronchial biopsy specimens can create diagnostic dilemmas for all pathologists regardless of level of training. The elimination of these artifacts should reduce the possibility of biopsy misinterpretation...
Granulomatous lung disease: an approach to the differential diagnosisSanjay Mukhopadhyay
Department of Pathology, State University of New York Upstate Medical University, Syracuse, New York 13210, USA
Arch Pathol Lab Med 134:667-90. 2010..Although most pathologists are aware of the need to exclude an infection in this setting, there is less familiarity with the specific histologic features that aid in the differential diagnosis...
Morphometry confirms the presence of considerable nuclear size overlap between "small cells" and "large cells" in high-grade pulmonary neuroendocrine neoplasmsA M Marchevsky
Department of Pathology, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA
Am J Clin Pathol 116:466-72. 2001..The use of more generic terminology such as "high-grade neuroendocrine carcinoma" or "grade III neuroendocrine carcinoma" for SCLC and LCNEC is discussed...
Saprophytic fungal infections and complications involving the bronchial anastomosis following human lung transplantationDavid R Nunley
Department of Internal Medicine, Andrew J McKelvey Lung Transplantation Center, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, GA 30322, USA
Chest 122:1185-91. 2002..To demonstrate an association between saprophytic fungal infections occurring at the bronchial anastomosis (BA) and the development of additional complications arising at this site...
Immunolocalization of erythropoietin and erythropoietin receptor in vestibular schwannomaD G Dillard
Department of Otolaryngology, Head and Neck Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA
Acta Otolaryngol 121:149-52. 2001..Using immunohistochemistry, we have demonstrated that both EPO and EPO-R are expressed in a majority of these tumors...
Eosinophilic pulmonary syndrome as a manifestation of GVHD following hematopoietic stem cell transplantation in three patientsM Akhtari
Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
Bone Marrow Transplant 43:155-8. 2009..Clinicians should be aware that eosinophilic pulmonary syndrome can occur following HSCT, may be associated with other manifestations of chronic GVHD, and generally responds well to corticosteroid therapy...
Transforming growth factor and neutralizing antibodies in subglottic stenosisD G Dillard
Department of Otolaryngology, Atlanta Veterans Administration Medical Center and Emory University School of Medicine, Georgia, USA
Ann Otol Rhinol Laryngol 110:393-400. 2001..In contrast, neutralizing antibodies led to a decrease in extracellular matrix protein expression. These findings suggest that TGF-beta1 may possibly play a role in the pathogenesis of subglottic stenosis...
Receptor for advanced glycation end products in donor lungs is associated with primary graft dysfunction after lung transplantationA Pelaez
Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine, Atlanta, GA, USA
Am J Transplant 10:900-7. 2010..These findings also raise the possibility that targeting the RAGE signaling pathway could be a novel strategy for treatment and/or prevention of PGD...
Dynamics of human regulatory T cells in lung lavages of lung transplant recipientsDavid C Neujahr
McKelvey Center for Lung Transplantation and Pulmonary Vascular Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA
Transplantation 88:521-7. 2009..Early rejection is a risk factor for the development of chronic rejection. In animal models of transplant tolerance, regulatory T cells (Tregs) can prevent the establishment of rejection...
Updated protocol for the examination of specimens from patients with carcinoma of the lungAnthony A Gal
Department of Pathology and Laboratory Medicine, Emory University Hospital, Atlanta, GA, USA
Arch Pathol Lab Med 127:1304-13. 2003
High tumor grade in salivary gland mucoepidermoid carcinomas and loss of expression of transforming growth factor beta receptor type IID G Dillard
Department of Pathology and Laboratory Medicine, 1364 Clifton Rd NE, Atlanta, GA 30322, USA
Arch Otolaryngol Head Neck Surg 127:683-6. 2001..The localization of activated TGF-beta1 within neoplastic epithelium, tumor-associated stroma, and endothelium suggests that it might play a role in the stromal proliferation and/or angiogenesis associated with MEC...
Pulmonary alveolar proteinosis mimicking idiopathic pulmonary fibrosisZoya K Arbiser
Department of Pathology and Laboratory Medicine, Emory University Hospital, Atlanta, GA 30322, USA
Ann Diagn Pathol 7:82-6. 2003..Because the clinical and radiographic presentation of PAP can overlap with other interstitial lung disorders, it should be considered in the differential diagnosis of unexplained idiopathic interstitial pneumonias in young patients...
High-resolution computed tomography appearance of pulmonary Mycobacterium avium complex infection after exposure to hot tub: case of hot-tub lungRobert V Pham
Department of Radiology, Emory University School of Medicine, Atlanta, Georgia, USA
J Thorac Imaging 18:48-52. 2003..Correlation of clinical history with radiographic, pathologic, and microbiologic findings are necessary to establish a diagnosis of hot-tub lung...
Current concepts in the classification of interstitial lung diseaseAnthony A Gal
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
Am J Clin Pathol 123:S67-81. 2005..In this review, the highlights of this classification are presented, along with recommended guidelines for handling lung biopsy specimens and diagnosing interstitial lung diseases...
Pathology and pathogenesis of fatal Bordetella pertussis infection in infantsChristopher D Paddock
Infectious Disease Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 47:328-38. 2008....
The morphologic spectrum of metastatic prostatic adenocarcinoma to the lung: special emphasis on histologic features overlapping with other pulmonary neoplasmsJohn N Copeland
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
Am J Clin Pathol 117:552-7. 2002..Attention to specific discriminating histologic features, supported by immunohistochemical staining, may be useful in the differential diagnosis, which is therapeutically and prognostically critical...
Asthma as a consequence of bone marrow transplantationHeather Rietz
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
Chest 122:369-70. 2002..A diagnosis of asthma should be entertained in the differential diagnosis of pulmonary complications in bone marrow transplant recipients...
