Research Topics
| W D FlandersSummaryAffiliation: Emory University Country: USA Publications
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Publications
Dependence of confounding on the target population: a modification of causal graphs to account for co-actionW Dana Flanders
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Ann Epidemiol 21:698-705. 2011..We propose a simple modification of DAG rules to overcome this limitation...
Tests of trait-haplotype association when linkage phase is ambiguous, appropriate for matched case-control and cohort studies with competing risksW D Flanders
Department of Epidemiology, Rollins School of Public Health, Emory University, 1599 Clifton Road, Atlanta, GA 30322, USA
Stat Med 24:2299-316. 2005....
Predictors of improved HbA1c testing by primary care physiciansW Dana Flanders
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA
J Health Care Poor Underserved 16:720-33. 2005..Physicians in counties with more people on Medicaid, or with fewer physicians per capita tended to have less improvement in HbA1c testing among Medicare beneficiaries over the three year study period...
Properties of 2 counterfactual effect definitions of a point exposureW Dana Flanders
Department of Epidemiology and Biostatistics, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Epidemiology 18:453-60. 2007..We present implications for study design, and make several recommendations. Problems may be reduced or avoided by starting follow-up before onset of exposure and by using survival curves to compare exposed with unexposed...
A method for detection of residual confounding in time-series and other observational studiesW Dana Flanders
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Epidemiology 22:59-67. 2011....
Adjusting for reverse causality in the relationship between obesity and mortalityW D Flanders
Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Int J Obes (Lond) 32:S42-6. 2008..Analyses should be balanced with sensitivity approaches as well as with alternative analytic approaches such as the use of structural models, G-estimation, simulations and ancillary data from animal studies...
On the relationship of sufficient component cause models with potential outcome (counterfactual) modelsW Dana Flanders
Emory University, Rollins School of Public Health, Atlanta, GA 30345, USA
Eur J Epidemiol 21:847-53. 2006..Recognition of the links between the two models should allow greater insight into use of each model, and allow the strengths of both models to be used jointly...
A method to detect residual confounding in spatial and other observational studiesW Dana Flanders
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Epidemiology 22:823-6. 2011..A related question addressed here is whether an analogous indicator can be used to identify residual confounding in a study based on spatial, rather than temporal, contrasts...
Ambient air pollution and cardiovascular emergency department visits in potentially sensitive groupsJennifer L Peel
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA
Am J Epidemiol 165:625-33. 2007..These findings provide further evidence of increased susceptibility to adverse cardiovascular events associated with ambient air pollution among persons with hypertension, diabetes, and COPD...
New estimator of the genotype risk ratio for use in case-parental control studiesW D Flanders
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Am J Epidemiol 154:259-63. 2001..The authors also suggest a way to combine estimates from families in which one parent and one offspring are observed and estimates from families in which both parents and one offspring are observed...
MutL-homolog 1 expression and risk of incident, sporadic colorectal adenoma: search for prospective biomarkers of risk for colorectal cancerEduard Sidelnikov
Department of Epidemiology, Emory University, Atlanta, GA 30322, USA
Cancer Epidemiol Biomarkers Prev 18:1599-609. 2009....
Ambient air pollution and cardiac arrhythmias in patients with implantable defibrillatorsKristina B Metzger
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Epidemiology 18:585-92. 2007..Previous studies of ambient air pollution and ventricular tachyarrhythmias in patients with implantable cardioverter defibrillators have yielded mixed results...
Accounting for unmeasured population substructure in case-control studies of genetic association using a novel latent-class modelG A Satten
Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Hum Genet 68:466-77. 2001..We have tested our approach using simulated data based on allele frequencies in 12 short tandem repeat (STR) loci in four populations in Argentina...
Genetic epidemiologic methods to screen for matrilineal inheritance in mitochondrial disordersF Mili
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Genet Epidemiol 13:605-14. 1996..To illustrate our epidemiologic method, we apply our screening method to pedigrees of two disorders which have been proposed to have a mitochondrial DNA component to their inheritance...
Evaluating the exposure and disease relationship with adjustment for different types of exposure misclassification: a regression approachA S Kosinski
Department of Biostatistics, The Rollins School of Public Health, 1518 Clifton Road, N E, Emory University, Atlanta, Georgia 30322, USA
Stat Med 18:2795-808. 1999..Standard statistical packages with a logistic regression module can be used for estimation of parameters through the EM algorithm process. Two examples are used to illustrate the methodology...
Ambient air pollution and preterm birth: a time-series analysisLyndsey A Darrow
Rollins School of Public Health, Emory University, Atlanta, GA, USA
Epidemiology 20:689-98. 2009..An emerging body of evidence suggests that ambient levels of air pollution during pregnancy are associated with preterm birth...
Ambient air pollution and respiratory emergency department visitsJennifer L Peel
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
Epidemiology 16:164-74. 2005..More refined assessment has been limited by study size and available air quality data...
How many genes underlie the occurrence of common complex diseases in the population?Quanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention CDC, Atlanta, GA 30333, USA
Int J Epidemiol 34:1129-37. 2005..It is not clear how many genes are necessary to account for an appreciable population-attributable fraction of these diseases...
Ambient air pollution and cardiovascular malformations in Atlanta, Georgia, 1986-2003Matthew J Strickland
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Am J Epidemiol 169:1004-14. 2009..60, 95% confidence interval: 1.11, 2.31). Of the 60 associations examined in the primary analysis, no other significant associations were observed...
Mid-pregnancy maternal plasma levels of interleukin 2, 6, and 12, tumor necrosis factor-alpha, interferon-gamma, and granulocyte-macrophage colony-stimulating factor and spontaneous preterm deliveryAllison E Curry
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Acta Obstet Gynecol Scand 86:1103-10. 2007..The authors examine whether mid-pregnancy plasma cytokine levels are associated with sPTD, and whether associations vary by maternal age, body mass index, prior preterm delivery, or gravidity...
An examination of exposure measurement error from air pollutant spatial variability in time-series studiesStefanie E Sarnat
Emory University, Atlanta, Georgia 30322, USA
J Expo Sci Environ Epidemiol 20:135-46. 2010..Overall, our findings lend support to the use of pollutant data from urban central sites to assess population exposures within geographically dispersed study populations in Atlanta and similar cities...
A summary measure of pro- and anti-oxidant exposures and risk of incident, sporadic, colorectal adenomasMichael Goodman
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Cancer Causes Control 19:1051-64. 2008..0. The corresponding analysis for community controls showed a similar trend. Our findings are in line with the basic science evidence supporting the role of oxidative stress in colorectal neoplasia...
Drinking water residence time in distribution networks and emergency department visits for gastrointestinal illness in Metro Atlanta, GeorgiaSarah C Tinker
Department of Environmental and Occupational Health, Emory University, Atlanta, GA 30322, USA
J Water Health 7:332-43. 2009..07, 95% confidence interval (CI) = 1.03, 1.10; OR for Utility 2 = 1.05, 95% CI = 1.02, 1.08). The results suggest that drinking water contamination in the distribution system may contribute to the burden of endemic GI illness...
Drinking water turbidity and emergency department visits for gastrointestinal illness in Atlanta, 1993-2004Sarah C Tinker
Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
J Expo Sci Environ Epidemiol 20:19-28. 2010....
Seasonality of birth and implications for temporal studies of preterm birthLyndsey A Darrow
Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
Epidemiology 20:699-706. 2009..To illustrate, we describe the seasonal patterns of birth in Atlanta and demonstrate how these patterns could lead to confounding in time-series studies of seasonally-varying exposures and preterm birth...
Role of prenatal characteristics and early growth on pubertal attainment of British girlsMildred Maisonet
National Center for Environmental Health, Centers for Disease Control and Prevention, 1518 Clifton Road NE, Atlanta, GA 30322, USA
Pediatrics 126:e591-600. 2010....
Progression through puberty in girls enrolled in a contemporary British cohortKrista Y Christensen
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
J Adolesc Health 47:282-9. 2010..We used data from a longitudinal cohort to describe factors associated with breast and pubic hair stage and estimate average duration of puberty...
Short-term associations between ambient air pollutants and pediatric asthma emergency department visitsMatthew J Strickland
Department of Environmental and Occupational Health, Atlanta, GA 30322, USA
Am J Respir Crit Care Med 182:307-16. 2010..To advance understanding of these relationships, further characterization of the dose-response and pollutant lag effects are needed, as are investigations of pollutant species beyond the commonly measured criteria pollutants...
Combined measure of pro- and anti-oxidant exposures in relation to prostate cancer and colorectal adenoma risk: an updateMichael Goodman
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Ann Epidemiol 20:955-7. 2010..In the present study we extend our analysis by substituting questionnaire-based measures with systemic biomarkers of pro- and anti-oxidant exposures...
Hypothesis: oxidative stress score as a combined measure of pro-oxidant and antioxidant exposuresMichael Goodman
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Ann Epidemiol 17:394-9. 2007..To explore the hypothesis that a combination of several risk factors acting through the same pathway may produce an overall large increase in risk even in the presence of weak associations with each individual factor...
Improved diabetes care by primary care physicians: results of a group-randomized evaluation of the Medicare Health Care Quality Improvement Program (HCQIP)William M McClellan
Georgia Medical Care Foundation, 1455 Lincoln Parkway, Suite 500, Atlanta, GA 30346, USA
J Clin Epidemiol 56:1210-7. 2003..Determine if an intervention that includes claims-based feedback about patterns of HbA1C measurement results in more frequent monitoring of HbA1C in diabetic Medicare beneficiaries...
Robust statistical methods for analysis of biomarkers measured with batch/experiment-specific errorsQi Long
Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA 30322, U S A
Stat Med 29:361-70. 2010..Our methods are illustrated using a biomarker validation case-control study for colorectal neoplasms...
Ambient air pollution and cardiovascular emergency department visitsKristi Busico Metzger
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Epidemiology 15:46-56. 2004..This time-series study examined the relation between ambient air pollution and cardiovascular conditions using ambient air quality data and emergency department visit data in Atlanta, Georgia, from January 1, 1993, to August 31, 2000...
Residential carbon monoxide alarm prevalence and ordinance awarenessShahed Iqbal
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Public Health Manag Pract 18:272-8. 2012..This study determined the prevalence of residential CO alarm and awareness of a 2001 CO alarm ordinance in Mecklenburg County, North Carolina in 2009...
Interim results of the study of particulates and health in Atlanta (SOPHIA)P E Tolbert
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
J Expo Anal Environ Epidemiol 10:446-60. 2000..5 EC and PM2.5 OM. While covariation of many of the air quality indices limits the informativeness of this analysis, the study provides one of the first assessments of PM components in relation to ED visits...
Carotid endarterectomy among Medicare beneficiaries: a statewide evaluation of appropriateness and outcomeH R Karp
Georgia Medical Care Foundation, Emory University, Atlanta 30329 2224, USA
Stroke 29:46-52. 1998..We sought to examine the appropriateness and the surgical outcomes of carotid endarterectomy (CE) in unselected community hospitals to identify opportunities for improvement...
Blood 25-hydroxyvitamin D3 concentrations and incident sporadic colorectal adenoma risk: a pooled case-control studyVeronika Fedirko
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Am J Epidemiol 172:489-500. 2010..These findings support the hypothesis that greater vitamin D exposure may reduce the risk of colorectal adenoma and suggest that it may do so more strongly in combination with antiinflammatory agents...
Meat consumption and risk of colorectal cancerAnn Chao
Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329-4251, USA
JAMA 293:172-82. 2005....
Colorectal mucosal expression of MSH2 as a potential biomarker of risk for colorectal neoplasmsEduard Sidelnikov
Department of Epidemiology, Rollins School of Public Health, and Winship Cancer Institute, Emory University, 1518 Clifton Road Northeast, Atlanta, Georgia 30322, USA
Cancer Epidemiol Biomarkers Prev 18:2965-73. 2009....
Comparing methods for accounting for seasonal variability in a biomarker when only a single sample is available: insights from simulations based on serum 25-hydroxyvitamin dYiting Wang
Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, USA
Am J Epidemiol 170:88-94. 2009..To avoid potential bias away from the null, using season- or month-specific cutpoints may be preferable to adjusting for DOSC...
Predictors of correct treatment of children with fever seen at outpatient health facilities in the Central African RepublicA K Rowe
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Epidemiol 151:1029-35. 2000..For child health programs to improve, targeted studies are needed to understand which factors, alone or in combination, improve health care worker performance...
Effects of supplemental vitamin D and calcium on oxidative DNA damage marker in normal colorectal mucosa: a randomized clinical trialVeronika Fedirko
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
Cancer Epidemiol Biomarkers Prev 19:280-91. 2010....
Effects of calcium and vitamin D on MLH1 and MSH2 expression in rectal mucosa of sporadic colorectal adenoma patientsEduard Sidelnikov
Department of Epidemiology, Rollins School of Public Health, Atlanta, GA, USA
Cancer Epidemiol Biomarkers Prev 19:1022-32. 2010....
Evaluation of associations between lifetime exposure to drinking water disinfection by-products and bladder cancer in dogsLorraine C Backer
National Center for Environmental Health, CDC, Atlanta, GA 30341, USA
J Am Vet Med Assoc 232:1663-8. 2008..To assess the risk of bladder cancer in dogs from exposure to drinking water disinfection by-products and determine whether dogs could serve as sentinels for human bladder cancer associated with such exposures...
Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer CancersMarjorie L McCullough
American Cancer Society, Atlanta, Georgia 30303 1002, USA
Am J Epidemiol 172:21-35. 2010..Correlates varied somewhat within season, race/ethnicity, and sex. These findings help identify persons at risk for low vitamin D status for both clinical and research purposes...
Characterization of the correlation between ages at entry into breast and pubic hair developmentKrista Yorita Christensen
Epidemiology Department, Emory University, Atlanta, GA 30322, USA
Ann Epidemiol 20:405-8. 2010..The timing of breast and pubic hair development in girls are related, but the degree of correlation has not been well characterized. Periodic observations also are complicated by interval censoring...
Health-related quality of life of U.S. military personnel: a population-based studyDrue H Barrett
Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Mil Med 168:941-7. 2003..CONCLUSIONS: Recommendations are made to monitor HRQOL of active duty and reserve personnel over time and to include HRQOL measures in military-based surveys of active duty troops...
Leanness and lung cancer risk: fact or artifact?S Jane Henley
Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329, USA
Epidemiology 13:268-76. 2002....
Are nitrate levels in groundwater stable over time?Perri Zeitz Ruckart
Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30333, USA
J Expo Sci Environ Epidemiol 18:129-33. 2008..This observation showed that a single measurement of nitrate in water from drilled wells could represent longer periods of exposure...
Lung cancer mortality in relation to age, duration of smoking, and daily cigarette consumption: results from Cancer Prevention Study IIW Dana Flanders
Department of Epidemiology and Surveillance, American Cancer Society, Atlanta, GA 30329, USA
Cancer Res 63:6556-62. 2003..We discuss reasons why the associations we observe are lower than those reported by R. Doll and R. Peto (J. Epidemiol. Commun. Health, 32: 303-313, 1978)...
Blood lead levels and risk factors for lead poisoning among children in Jakarta, IndonesiaRachel Albalak
Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, 1600 Clifton Rd Mailstop E 19, Atlanta, GA 30333, USA
Sci Total Environ 301:75-85. 2003..With the phase-out of leaded gasoline, BLLs of children in Jakarta are expected to rapidly decline as they have in other countries that have phased lead out of gasoline...
Comparison of emergency department and hospital admissions data for air pollution time-series studiesA Winquist
Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
Environ Health 11:70. 2012....
Race, neighbourhood characteristics and disparities in chemotherapy for colorectal cancerY Hao
Surveillance and Health Policy Research, American Cancer Society, Atlanta, Georgia, USA
J Epidemiol Community Health 65:211-7. 2011..Studies have found significant race/ethnic and age differences in receipt of adjuvant chemotherapy for stages III colon and II/III rectal cancers. Little is known about the role of neighbourhood factors in these disparities...
The issue of confounding in epidemiological studies of ambient air pollution and pregnancy outcomesM J Strickland
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
J Epidemiol Community Health 63:500-4. 2009..Although the three approaches share a common goal, to estimate the causal effects of pollution on pregnancy outcomes, they face different challenges with respect to confounding...
A modified cluster-sampling method for post-disaster rapid assessment of needsJ Malilay
Disaster Assessment and Epidemiology Section, Centers for Disease Control and Prevention, Atlanta, GA 30341 3724, USA
Bull World Health Organ 74:399-405. 1996....
Maternal plasma cytokines in early- and mid-gestation of normal human pregnancy and their association with maternal factorsA E Curry
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
J Reprod Immunol 77:152-60. 2008..In conclusion, cytokines were detected in plasma during early- and mid-pregnancy, with IL-6, IL-12, IFN-gamma and GM-CSF concentrations varying over pregnancy. Concentrations may depend on BMI, maternal age and prior preterm delivery...
Can dialysis therapy be improved? A report from the ESRD Core Indicators ProjectW M McClellan
Renal Division, Emory University School of Medicine, Atlanta, GA, USA
Am J Kidney Dis 34:1075-82. 1999..We concluded that the sustained improvement in hemodialysis care that occurred after the inception of the ESRD Core Indicators Project was associated with specific ESRD Network interventions...
Cigarette smoking and changes in the histopathology of lung cancerM J Thun
Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
J Natl Cancer Inst 89:1580-6. 1997..g., the adoption of filtertips), or changes in smoking practices. We examined data from the Connecticut Tumor Registry and two American Cancer Society studies to explore these possibilities...
Effects of vitamin d and calcium on proliferation and differentiation in normal colon mucosa: a randomized clinical trialVeronika Fedirko
Department of Epidemiology, Rollins School of Public Health, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA
Cancer Epidemiol Biomarkers Prev 18:2933-41. 2009....
Why population attributable fractions can sum to more than oneAlexander K Rowe
Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
Am J Prev Med 26:243-9. 2004..For diseases with multiple risk factors, PAFs of individual risk factors can sum to more than 1, a result suggesting the impossible situation in which more than 100% of cases are preventable...
Blood lead levels and risk factors for lead poisoning among children in a Mexican smelting communityRachel Albalak
Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Arch Environ Health 58:172-83. 2003..BLLs in this study were moderately high, but the levels were lower than those in other smelting communities prior to remediation...
Renal insufficiency and anemia are independent risk factors for death among patients with acute myocardial infarctionRobert D Langston
Georgia Medical Care Foundation, Atlanta, Georgia 30346, USA
Kidney Int 64:1398-405. 2003..CONCLUSION: CKD and decreasing hematocrit were frequent among older patients hospitalized for acute myocardial infarction and are independent predictors of subsequent risk of death...
Risk factors for progressive chronic kidney diseaseWilliam M McClellan
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
J Am Soc Nephrol 14:S65-70. 2003..This should include active extension of our current understanding of health care, social, and economic risk factors at both the individual and the community level...
On the use of population attributable fraction to determine sample size for case-control studies of gene-environment interactionQuanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Epidemiology 14:161-7. 2003..In this case, the associated odds ratio for interaction will be weaker and a considerably larger sample size may be needed...
Anemia and renal insufficiency are independent risk factors for death among patients with congestive heart failure admitted to community hospitals: a population-based studyWilliam M McClellan
Georgia Medical Care Foundation, 57 Executive Park South, Suite 200, Atlanta, GA 30329, USA
J Am Soc Nephrol 13:1928-36. 2002..In conclusion, CKD and anemia are frequent among older patients with heart failure and are independent predictors of subsequent risk of death...
mtDNA mutations increase tumorigenicity in prostate cancerJohn A Petros
Department of Urology, Emory University, 1365A Clifton Road, Atlanta, GA 30322, USA
Proc Natl Acad Sci U S A 102:719-24. 2005..The mutant tumors also generated significantly more ROS. Therefore, mtDNA mutations do play an important role in the etiology of prostate cancer...
Lung cancer occurrence in never-smokers: an analysis of 13 cohorts and 22 cancer registry studiesMichael J Thun
American Cancer Society, Atlanta, Georgia, USA
PLoS Med 5:e185. 2008..Better information on lung cancer occurrence in lifelong nonsmokers is needed to understand gender and racial disparities and to examine how factors other than active smoking influence risk in different time periods and geographic regions...
The impact of excess heat events in Maricopa County, Arizona: 2000--2005Fuyuen Y Yip
Division of Environmental Hazards and Health Effects, National Center for Environmental Health Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MS f 57, Atlanta, GA 30341, USA
Int J Biometeorol 52:765-72. 2008..Consecutive days of heat exposure--even among a heat-acclimated population--can increase mortality risk. Public health response activities guided by locally obtained data will better target those at risk...
Investigating childhood leukemia in Churchill County, NevadaCarol S Rubin
National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Environ Health Perspect 115:151-7. 2007..Considering the county population and statewide cancer rate, fewer than two cases would be expected...
Community aerial mosquito control and naled exposureZandra Duprey
Health Studies Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry, Atlanta, GA 30341, USA
J Am Mosq Control Assoc 24:42-6. 2008..These data suggest that aerial spraying of naled does not result in increased levels of naled in humans, provided the naled is used according to label instructions...
Effects of vitamin D and calcium supplementation on markers of apoptosis in normal colon mucosa: a randomized, double-blind, placebo-controlled clinical trialVeronika Fedirko
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Cancer Prev Res (Phila) 2:213-23. 2009....
A process for sentinel case review to assess causal relationships between smallpox vaccination and adverse outcomes, 2003-2004Louisa E Chapman
Epidemiology and Surveillance Division, National Immunization Program, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 46:S271-93. 2008..This review of sentinel cases augmented the ongoing safety review process and was transparent, but it shares limitations with other case-based causality-assessment methods...
Residual spatial correlation between geographically referenced observations: a Bayesian hierarchical modeling approachHeather A Boyd
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
Epidemiology 16:532-41. 2005..We present a Bayesian hierarchical model (BHM) approach that accounts for spatial correlation, and illustrate its strengths and weaknesses by applying this modeling approach to data on Wuchereria bancrofti infection in Haiti...
Vitamin D status and impact of vitamin D3 and/or calcium supplementation in a randomized pilot study in the Southeastern United StatesMarjorie L McCullough
Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303 1002, USA
J Am Coll Nutr 28:678-86. 2009....
Reduction of elevated blood lead levels in children in North Carolina and Vermont, 1996-1999Timothy A Dignam
Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Emergency and Environmental Health Services, Lead Poisoning Prevention Branch, Atlanta, GA 30341, USA
Environ Health Perspect 116:981-5. 2008..Few studies have examined factors related to the time required for children's blood lead levels (BLLs) > or = 10 microg/dL to decline to < 10 microg/dL...
Aspirin and other nonsteroidal anti-inflammatory drugs and breast cancer incidence in a large U.S. cohortEric J Jacobs
Department of Epidemiology and Surveillance Research, American Cancer Society, National Home Office, 1599 Clifton Road Northeast, Atlanta, GA 30329 4251, USA
Cancer Epidemiol Biomarkers Prev 14:261-4. 2005..26 for total NSAIDs; RR, 0.88; 95% CI, 0.69-1.12 for aspirin). Although we cannot exclude a small reduction in breast cancer risk associated with NSAID use, the results of this study provide evidence against a large reduction in risk...
Seroprevalence of cytomegalovirus infection in the United States, 1988-1994Stephanie A S Staras
Department of Epidemiology, Emory University, Atlanta, GA 30322, USA
Clin Infect Dis 43:1143-51. 2006..However, there are no nationwide estimates of CMV seroprevalence among pregnant women or the overall population of the United States...
HIV intervention research for men who have sex with men: a 7-year updateWayne D Johnson
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30312, USA
AIDS Educ Prev 17:568-89. 2005..The other 16 interventions reduced unprotected sex by 17% beyond changes observed in standard or other HIV prevention interventions (CI = 5-27%). Behavioral interventions reduce self-reported unprotected sex among MSM...
Associations of maternal age- and parity-related factors with trends in low-birthweight rates: United States, 1980 through 2000Quanhe Yang
Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mail Stop E 86, Atlanta, GA 30333, USA
Am J Public Health 96:856-61. 2006..We assessed the effects of changes in the maternal age-parity distribution and age-and parity-specific low-birthweight rates on low-birthweight trends in the United States...
Using lifetime risk estimates in personal genomic profiles: estimation of uncertaintyQuanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Hum Genet 85:786-800. 2009..Epidemiologic parameters involved in computation of disease risk have substantial uncertainty, and cumulative uncertainty should be properly recognized. Reliance on point estimates alone could be seriously misleading...
Exogenous and endogenous determinants of blood trihalomethane levels after showeringLorraine C Backer
National Center for Environmental Health, Centers for Disease Control and Prevention, Chamblee, GA 30341, USA
Environ Health Perspect 116:57-63. 2008..Increases in blood THM levels among subjects who showered or bathed were variable, with increased levels tending to cluster in two groups...
Improving the prediction of complex diseases by testing for multiple disease-susceptibility genesQuanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Hum Genet 72:636-49. 2003..Multiplex genetic testing has the potential to improve the clinical validity of predictive testing for common multifactorial diseases...
Assessment of cumulative evidence on genetic associations: interim guidelinesJohn P A Ioannidis
Clinical and Molecular Epidemiology Unit, University of Ioannina School of Medicine, Ioannina 45110, Greece
Int J Epidemiol 37:120-32. 2008..Future empirical research and consensus development are needed to develop an integrated model for combining epidemiological and biological evidence in the rapidly evolving field of investigation of genetic factors...
Profiles of airborne fungi in buildings and outdoor environments in the United StatesBrian G Shelton
PathCon Laboratories, Norcross, Georgia 30092, USA
Appl Environ Microbiol 68:1743-53. 2002..This is the largest study of airborne indoor and outdoor fungal species and concentrations conducted with a standardized protocol to date...
High-intensity targeted screening for elevated blood lead levels among children in 2 inner-city Chicago communitiesTimothy A Dignam
Lead Poisoning Prevention Branch, Division of Emergency and Environmental Health Services, Centers for Disease Control and Prevention NIH, 4770 Buford Highway, Mail Stop F 40, Chamblee, GA 30341, USA
Am J Public Health 94:1945-51. 2004..We assessed the prevalence of elevated blood lead levels (> or = 10 micrograms of lead per deciliter of blood), risk factors, and previous blood lead testing among children in 2 high-risk Chicago, Ill, communities...
Variations in quality of care for heart failureJean Christophe Luthi
Health Care Evaluation Unit, Institute of Social and Preventive Medicine, University of Lausanne, Switzerland
Swiss Med Wkly 136:268-73. 2006..The objective of our study was to assess hospital-to-hospital variations for the management and treatment of heart failure (HF) patients...
Anemia and chronic kidney disease are associated with poor outcomes in heart failure patientsJean Christophe Luthi
Institute of Social and Preventive Medicine, University of Lausanne, Switzerland
BMC Nephrol 7:3. 2006..The purpose of this study was to examine among patients with HF, the association between CKD, anemia and inhospital mortality and early readmission...
Re: "estimating the proportion of disease due to classes of sufficient causes"Kurt Hoffmann
Am J Epidemiol 164:1254-5. 2006
Quality of health care surveillance systems: review and implementation in the Swiss settingJean Christophe Luthi
Health Care Evaluation Unit, Institute of Social and Preventive Medicine, University of Lausanne, Switzerland
Swiss Med Wkly 132:461-9. 2002..Priority needs to be given to quality indicators and methods with the highest level of evidence and with a solid scientific basis...
