W Michael Caudle

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc Industrial toxicants and Parkinson's disease
    W Michael Caudle
    Department of Environmental Health, Rollins School of Public Health, Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, United States
    Neurotoxicology 33:178-88. 2012
  2. pmc Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity
    Tonya N Taylor
    Center for Neurodegenerative Disease and Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 29:8103-13. 2009
  3. pmc Developmental heptachlor exposure increases susceptibility of dopamine neurons to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)in a gender-specific manner
    Jason R Richardson
    Center for Neurodegenerative Disease, School of Medicine, Emory University, Atlanta, GA 30322, United States
    Neurotoxicology 29:855-63. 2008
  4. pmc Exposure to the polybrominated diphenyl ether mixture DE-71 damages the nigrostriatal dopamine system: role of dopamine handling in neurotoxicity
    Joshua M Bradner
    Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322 3090, USA
    Exp Neurol 241:138-47. 2013
  5. ncbi request reprint Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1
    Cecily E Hamill
    Department of Pharmacology, Emory University School of Medicine, 5025 Rollins Research Center, 1510 Clifton Road, Atlanta, GA 30322, USA
    Mol Pharmacol 72:653-64. 2007
  6. ncbi request reprint Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity
    W Michael Caudle
    Department of Environmental and Occupational Health, Rollins School of Public Health and Center for Neurodegenerative Disease, School of Medicine, Emory University, Atlanta, Georgia 30322 3090, USA
    Toxicol Sci 92:490-9. 2006
  7. ncbi request reprint Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration
    W Michael Caudle
    Center for Neurodegenerative Disease, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 27:8138-48. 2007
  8. ncbi request reprint Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease
    Jason R Richardson
    Center for Neurodegenerative Disease, School of Medicine, Emory University, Atlanta, Georgia 30322, USA
    FASEB J 20:1695-7. 2006
  9. doi request reprint Altered vesicular dopamine storage in Parkinson's disease: a premature demise
    W Michael Caudle
    Center for Neurodegenerative Disease, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Trends Neurosci 31:303-8. 2008
  10. ncbi request reprint Perinatal heptachlor exposure increases expression of presynaptic dopaminergic markers in mouse striatum
    W Michael Caudle
    Center for Neurodegenerative Disease, Emory University, Whitehead Biomedical Research Building 505, 615 Michael Street, Atlanta, GA 30322, USA
    Neurotoxicology 26:721-8. 2005

Collaborators

  • James G Greene
  • Alison L McCormack
  • Donato A Di Monte
  • Hongjie Yuan
  • Gary W Miller
  • Jason R Richardson
  • Tonya N Taylor
  • Kurt D Pennell
  • Joshua M Bradner
  • E Danielle Dean
  • Cecily E Hamill
  • Jennifer L Tillerson
  • Mohamed A Elwan
  • Carlos R Lazo
  • Hye Mi Kim
  • Min Z Wang
  • Tiffany A Suragh
  • Kristen A Stout
  • Douglas I Walker
  • W Wyatt Wilson
  • David Weinshenker
  • P Michael Iuvone
  • Chad R Jackson
  • Kennie R Shepherd
  • AliReza Noorian
  • Min Zheng Wang
  • Stephen F Traynelis
  • Timothy Schallert
  • Thomas S Guillot
  • C Gong
  • Jack M Parent
  • Minzheng Wang

Detail Information

Publications14

  1. pmc Industrial toxicants and Parkinson's disease
    W Michael Caudle
    Department of Environmental Health, Rollins School of Public Health, Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, United States
    Neurotoxicology 33:178-88. 2012
    ....
  2. pmc Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity
    Tonya N Taylor
    Center for Neurodegenerative Disease and Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 29:8103-13. 2009
    ..Furthermore, monoamine dysfunction may contribute to many of the nonmotor symptoms of PD, and interventions aimed at restoring monoamine function may be beneficial in treating the disease...
  3. pmc Developmental heptachlor exposure increases susceptibility of dopamine neurons to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)in a gender-specific manner
    Jason R Richardson
    Center for Neurodegenerative Disease, School of Medicine, Emory University, Atlanta, GA 30322, United States
    Neurotoxicology 29:855-63. 2008
    ..These data suggest that developmental heptachlor exposure causes long-term alterations of the dopamine system thereby rendering it more susceptible to dopaminergic damage in adulthood...
  4. pmc Exposure to the polybrominated diphenyl ether mixture DE-71 damages the nigrostriatal dopamine system: role of dopamine handling in neurotoxicity
    Joshua M Bradner
    Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322 3090, USA
    Exp Neurol 241:138-47. 2013
    ..Given their similarities to PCBs, additional laboratory and epidemiological research should be considered to assess PBDEs as a potential risk factor for PD and other neurological disorders...
  5. ncbi request reprint Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1
    Cecily E Hamill
    Department of Pharmacology, Emory University School of Medicine, 5025 Rollins Research Center, 1510 Clifton Road, Atlanta, GA 30322, USA
    Mol Pharmacol 72:653-64. 2007
    ..Together, these data suggest that PAR1 might be a target for therapeutic intervention in Parkinson's disease...
  6. ncbi request reprint Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity
    W Michael Caudle
    Department of Environmental and Occupational Health, Rollins School of Public Health and Center for Neurodegenerative Disease, School of Medicine, Emory University, Atlanta, Georgia 30322 3090, USA
    Toxicol Sci 92:490-9. 2006
    ..Furthermore, DAT imaging may be useful in evaluating alterations in brain function in human populations exposed to PCBs...
  7. ncbi request reprint Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration
    W Michael Caudle
    Center for Neurodegenerative Disease, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 27:8138-48. 2007
    ..In addition, the altered dopamine homeostasis resulting from reduced VMAT2 function may be conducive to pathogenic mechanisms induced by genetic or environmental factors thought to be involved in Parkinson's disease...
  8. ncbi request reprint Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease
    Jason R Richardson
    Center for Neurodegenerative Disease, School of Medicine, Emory University, Atlanta, Georgia 30322, USA
    FASEB J 20:1695-7. 2006
    ....
  9. doi request reprint Altered vesicular dopamine storage in Parkinson's disease: a premature demise
    W Michael Caudle
    Center for Neurodegenerative Disease, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Trends Neurosci 31:303-8. 2008
    ..This review seeks to revisit the pathogenicity of cytosolic dopamine and further address the critical role of neurotransmitter storage in dopamine-mediated neurotoxicity...
  10. ncbi request reprint Perinatal heptachlor exposure increases expression of presynaptic dopaminergic markers in mouse striatum
    W Michael Caudle
    Center for Neurodegenerative Disease, Emory University, Whitehead Biomedical Research Building 505, 615 Michael Street, Atlanta, GA 30322, USA
    Neurotoxicology 26:721-8. 2005
    ....
  11. ncbi request reprint Olfactory discrimination deficits in mice lacking the dopamine transporter or the D2 dopamine receptor
    Jennifer L Tillerson
    Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA
    Behav Brain Res 172:97-105. 2006
    ..The findings presented in this paper reinforce the functional significance of dopamine and more specifically the D2 receptor in olfactory discrimination and may help explain the behavioral phenotype in the DAT and D2 knockout mice...
  12. ncbi request reprint Use-dependent behavioral and neurochemical asymmetry in MPTP mice
    W Michael Caudle
    Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA
    Neurosci Lett 418:213-6. 2007
    ..These results show a significant interaction between behavior and neurochemistry and suggest that a reduction in activity level may further exacerbate degeneration...
  13. pmc VMAT2-Deficient Mice Display Nigral and Extranigral Pathology and Motor and Nonmotor Symptoms of Parkinson's Disease
    Tonya N Taylor
    Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA
    Parkinsons Dis 2011:124165. 2011
    ..The multisystem nature of the VMAT2-deficient mice may be useful in developing therapeutic strategies that go beyond the dopamine system...
  14. ncbi request reprint Pyrethroid pesticide-induced alterations in dopamine transporter function
    Mohamed A Elwan
    Center for Neurodegenerative Disease, School of Medicine, Emory University, Atlanta, GA 30322, USA
    Toxicol Appl Pharmacol 211:188-97. 2006
    ....