Elisabeth B Binder

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi request reprint Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Nat Genet 36:1319-25. 2004
  2. pmc Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Munchen, Germany
    Neuropsychopharmacology 35:1583-92. 2010
  3. ncbi request reprint Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders
    Angelika Erhardt
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, D 80804 München, Germany
    J Affect Disord 101:159-68. 2007
  4. doi request reprint Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Arch Gen Psychiatry 67:369-79. 2010
  5. doi request reprint Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions
    Torsten Klengel
    Max Planck Institute of Psychiatry, Munich, Germany
    Nat Neurosci 16:33-41. 2013
  6. ncbi request reprint Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 München, Germany
    J Affect Disord 105:177-84. 2008
  7. doi request reprint A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    Arch Gen Psychiatry 66:966-75. 2009
  8. doi request reprint Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression
    Manfred Uhr
    Max Planck Institute of Psychiatry, Kraepelinstr 10, 80804 Munich, Germany
    Neuron 57:203-9. 2008
  9. doi request reprint Rare variants in TMEM132D in a case-control sample for panic disorder
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 159:896-907. 2012
  10. pmc Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients
    Andreas Menke
    Moleculargenetics of Affective Disorders, Max Planck Institute of Psychiatry, Kraepelinstr, Munich, Germany
    Neuropsychopharmacology 37:1455-64. 2012

Detail Information

Publications58

  1. ncbi request reprint Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Nat Genet 36:1319-25. 2004
    ..These findings support a central role of genes regulating the HPA axis in the causality of depression and the mechanism of action of antidepressant drugs...
  2. pmc Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Munchen, Germany
    Neuropsychopharmacology 35:1583-92. 2010
    ..The reported associations in independent samples of AD and MDD support an estrogen-dependent function of GAL in pathophysiology of anxiety and depression, affecting response to antidepressant treatment...
  3. ncbi request reprint Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders
    Angelika Erhardt
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, D 80804 München, Germany
    J Affect Disord 101:159-68. 2007
    ..This region contains two candidate genes for purinergic ligand-gated ion channels, P2RX7 and P2RX4, and one gene coding for calmodulin-dependent protein kinase kinase b (CaMKKb)...
  4. doi request reprint Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Arch Gen Psychiatry 67:369-79. 2010
    ..The corticotropin-releasing factor (CRF, or corticotropin-releasing hormone) and arginine vasopressin systems have been implicated in the pathophysiology of anxiety and depressive disorders and response to antidepressant treatment...
  5. doi request reprint Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions
    Torsten Klengel
    Max Planck Institute of Psychiatry, Munich, Germany
    Nat Neurosci 16:33-41. 2013
    ..This identification of molecular mechanisms of genotype-directed long-term environmental reactivity will be useful for designing more effective treatment strategies for stress-related disorders...
  6. ncbi request reprint Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 München, Germany
    J Affect Disord 105:177-84. 2008
    ..Furthermore, GAL is involved in hypothalamic-hypophysiotropic signalling and cosecreted with luteinizing hormone-releasing hormone (LHRH), possibly acting as a mediator of estrogen action...
  7. doi request reprint A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    Arch Gen Psychiatry 66:966-75. 2009
    ..Genetic factors and clinical characteristics contribute to the failure of a favorable treatment outcome...
  8. doi request reprint Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression
    Manfred Uhr
    Max Planck Institute of Psychiatry, Kraepelinstr 10, 80804 Munich, Germany
    Neuron 57:203-9. 2008
    ..This finding can be viewed as a further step into personalized antidepressant treatment...
  9. doi request reprint Rare variants in TMEM132D in a case-control sample for panic disorder
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 159:896-907. 2012
    ..Our data suggest that not only common but also putatively functional and/or rare variants within TMEM132D might contribute to the risk to develop anxiety disorders...
  10. pmc Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients
    Andreas Menke
    Moleculargenetics of Affective Disorders, Max Planck Institute of Psychiatry, Kraepelinstr, Munich, Germany
    Neuropsychopharmacology 37:1455-64. 2012
    ....
  11. doi request reprint Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes
    Andreas Menke
    Max Planck Institute of Psychiatry, Kraepelinstr 10, D 80804 Munich, Germany
    Psychoneuroendocrinology 37:565-75. 2012
    ....
  12. pmc Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 35:727-40. 2010
    ....
  13. pmc Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients
    Martin A Kohli
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D 80804 Munich, Germany
    Arch Gen Psychiatry 67:348-59. 2010
    ..Especially in suicide victims, lower postmortem brain messenger RNA and protein levels of neurotrophins and their receptors have been reported...
  14. pmc Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies
    Divya Mehta
    Max Planck Institute of Psychiatry, Kraepelinstrasse, Munich, Germany
    Arch Gen Psychiatry 68:901-10. 2011
    ..Polymorphisms in the gene encoding the glucocorticoid receptor (GR) regulating co-chaperone FKBP5 have been shown to alter GR sensitivity and are associated with an increased risk to develop posttraumatic stress disorder (PTSD)...
  15. ncbi request reprint Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Munchen, Germany
    Am J Med Genet B Neuropsychiatr Genet 144:424-9. 2007
    ..These results further underline a possible important role of genetic variations within the system controlling serotonergic neurotransmission for the development and course of disease in PD...
  16. doi request reprint Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project
    Johannes M Hennings
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    J Psychiatr Res 43:215-29. 2009
    ..We demonstrated that this subgroup can be characterized by a set of demographic, clinical and neuroendocrine variables allowing to predict unfavorable outcome at an early stage of treatment...
  17. ncbi request reprint Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder
    Angelika Erhardt
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 31:2515-22. 2006
    ..However, differences in the suppression effects and psychopathological correlation patterns between depressed and panic patients suggest different biological mechanisms of HPA system dysregulation in both disorders...
  18. doi request reprint Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder
    Martin E Keck
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:1196-204. 2008
    ..These data suggest that polymorphisms in the AVPR1B and the CRHR1 genes alter the susceptibility to panic disorder...
  19. ncbi request reprint Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker?
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:47-54. 2007
    ..In the present study, we examined whether change in HPA system function during the first weeks of hospitalization predicts response to antidepressant treatment in major depression and thus constitutes a potential biomarker...
  20. ncbi request reprint Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis
    Hubertus Himmerich
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 60:882-8. 2006
    ....
  21. pmc Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder
    Divya Mehta
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Proc Natl Acad Sci U S A 110:8302-7. 2013
    ..These results contribute to a better understanding of the extent of influence of differences in trauma exposure on pathophysiological processes in stress-related psychiatric disorders and may have implications for personalized medicine...
  22. pmc The neuronal transporter gene SLC6A15 confers risk to major depression
    Martin A Kohli
    Max Planck Institute of Psychiatry, D 80804 Munich, Germany
    Neuron 70:252-65. 2011
    ..Our convergent data from human genetics, expression studies, brain imaging, and animal models suggest a pathophysiological mechanism for MD that may be accessible to drug targeting...
  23. pmc Genome-wide association study of antidepressant treatment-emergent suicidal ideation
    Andreas Menke
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 37:797-807. 2012
    ..Although our data need to be interpreted carefully owing to the small numbers in both cohorts, they suggest that a combination of genetic markers might indeed be used to identify patients at risk for TESI...
  24. doi request reprint Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Munchen, Germany
    Am J Med Genet B Neuropsychiatr Genet 150:1100-9. 2009
    ..However, data from expression studies imply that these polymorphisms could tag functional effects on the neighboring gene MYO3A, which is also expressed in the brain, including the cingulate cortex and the amygdala...
  25. ncbi request reprint Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks
    Christoph K Thoeringer
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    J Psychiatr Res 41:579-84. 2007
    ..43; 95% CI: 0.19-0.95). In conclusion, these results suggest a central role of DBI genetic variants in the susceptibility for the development of anxiety disorders that are characterized by the occurrence of panic attacks...
  26. ncbi request reprint P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
    Susanne Lucae
    The Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Mol Genet 15:2438-45. 2006
    ..This polymorphism results in an amino acid exchange in the C-terminal cytosolic domain of the P2RX7 channel protein, suggesting that the observed P2RX7 polymorphism might play a causal role in the development of depression...
  27. pmc Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study
    Petra Zimmermann
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Psychiatry 168:1107-16. 2011
    ..The authors explored gene-environment interactions between FKBP5 gene variants and adverse life events in predicting the first occurrence of a major depressive episode...
  28. doi request reprint Pharmacogenomics of antidepressant drugs
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Pharmacol Ther 124:57-73. 2009
    ..Illustrated by examples from current candidate gene- and whole genome association studies, this manuscript critically discusses aspects of pharmacogenetic studies in antidepressant response related to study design and clinical relevance...
  29. pmc Expression and regulation of the Fkbp5 gene in the adult mouse brain
    Sebastian H Scharf
    Research Group Molecular Stress Physiology, Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 6:e16883. 2011
    ....
  30. doi request reprint The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Munich, Germany
    Psychoneuroendocrinology 34:S186-95. 2009
    ..In addition, they are also associated with faster response to antidepressant treatment. FKBP5 might thus be an interesting therapeutic target for the prevention and treatment of stress-related psychiatric disorders...
  31. ncbi request reprint The combined dexamethasone/CRH test as a potential surrogate marker in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Kraepelinstr 10, D 80804 Munich, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 29:1085-93. 2005
    ..Further systematic research is required and already ongoing to confirm the suitability of the combined dex/CRH test as a surrogate marker in depression...
  32. ncbi request reprint Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression
    Andrea Pfennig
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 57:336-42. 2005
    ..So far data on the involvement of the HPA axis in the pathophysiology of suicidal behavior in depressed patients are controversial...
  33. pmc Functional coding variants in SLC6A15, a possible risk gene for major depression
    Carina Quast
    Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 8:e68645. 2013
    ..As statistically significant association for rare variants might only be achieved in extremely large samples (N >70,000) functional exploration may shed light on putatively disease-relevant variants...
  34. ncbi request reprint Epigenetics, depression and antidepressant treatment
    Andreas Menke
    Max Planck Institute of Psychiatry, Munich, Germany
    Curr Pharm Des 18:5879-89. 2012
    ..Most notably, epigenetic alterations are potentially reversible and accessibe for drug treatment, which lead to the development of novel classes of antidepressant drugs...
  35. ncbi request reprint Toward a reliable distinction between patients with mild cognitive impairment and Alzheimer-type dementia versus major depression
    Anke Post
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 59:858-62. 2006
    ....
  36. doi request reprint Gene × environment interactions in the prediction of response to antidepressant treatment
    Torsten Klengel
    Max Planck Institute of Psychiatry, Munich, Germany
    Int J Neuropsychopharmacol 16:701-11. 2013
    ..The elucidation of gene × environment interactions may thus not only help to understand the pathophysiology of MDD but could also provide markers for a personalized antidepressant therapy...
  37. pmc Gene expression studies in major depression
    Divya Mehta
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Curr Psychiatry Rep 12:135-44. 2010
    ..Finally, we discuss possible new strategies for the gene expression studies in MD that circumvent some of the addressed issues...
  38. ncbi request reprint Pharmacogenomics and antidepressant drugs
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Munich, Germany
    Ann Med 38:82-94. 2006
    ..These studies mark the beginning of an emerging standard SNP profiling system that ultimately allows identifying the right drug for the right patient at the right time...
  39. doi request reprint A beginners guide to SNP calling from high-throughput DNA-sequencing data
    Andre Altmann
    Statistical Genetics, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Genet 131:1541-54. 2012
    ..To this end, we employ several alignment programs and SNP calling routines for highlighting the fact that the choice of the tools significantly affects the final results...
  40. doi request reprint The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms
    Divya Mehta
    Max Planck Institute of Psychiatry, Munich, Germany
    J Affect Disord 136:1192-7. 2012
    ..The aim of this study was to evaluate the influence of stressful life events in combination with the serotonin transporter gene 5-HTTLPR polymorphism on peripartum depressive symptoms...
  41. pmc Peripheral blood gene expression: it all boils down to the RNA collection tubes
    Andreas Menke
    Max Planck Institute of Psychiatry, Kraepelinstr, 10, D 80804 Munich, Germany
    BMC Res Notes 5:1. 2012
    ..abstract:..
  42. pmc vipR: variant identification in pooled DNA using R
    Andre Altmann
    Department of Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany
    Bioinformatics 27:i77-84. 2011
    ..The resulting sequence data, however, poses a bioinformatics challenge: the discrimination of sequencing errors from real sequence variants present at a low frequency in the DNA pool...
  43. pmc Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms
    Kerry J Ressler
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 954 Gatewood Drive, Atlanta, GA 30329, USA
    Am J Med Genet B Neuropsychiatr Genet 153:812-24. 2010
    ....
  44. pmc Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
    Kerry J Ressler
    Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA
    Nature 470:492-7. 2011
    ..These sex-specific effects may occur via oestrogen regulation of ADCYAP1R1. PACAP levels and ADCYAP1R1 SNPs may serve as useful biomarkers to further our mechanistic understanding of PTSD...
  45. pmc Transcriptional signatures related to glucose and lipid metabolism predict treatment response to the tumor necrosis factor antagonist infliximab in patients with treatment-resistant depression
    Divya Mehta
    Max Planck Institute of Psychiatry, Munich, Germany
    Brain Behav Immun 31:205-15. 2013
    ....
  46. ncbi request reprint Gene-environment interactions in major depressive disorder
    Torsten Klengel
    Max Planck Institute of Psychiatry, Munich, Germany
    Can J Psychiatry 58:76-83. 2013
    ....
  47. doi request reprint Gene × environment vulnerability factors for PTSD: the HPA-axis
    Divya Mehta
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Neuropharmacology 62:654-62. 2012
    ..This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'...
  48. doi request reprint Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus
    Mathias V Schmidt
    Research Group Neurobiology of Stress, Max Planck Institute of Psychiatry, 80804 Munich, Germany
    J Neurosci 30:16949-58. 2010
    ..Those individual differences can be predicted by the assessment of short-term memory, thereby opening up the possibility for a specific treatment by enhancing AMPA receptor function...
  49. ncbi request reprint Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919)
    Anke Post
    Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 180:150-8. 2005
    ..Despite its therapeutic efficacy, there is only little information about its mechanisms of action on cellular and molecular targets...
  50. ncbi request reprint ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder
    Marianne B Muller
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Neuropsychopharmacology 28:1991-9. 2003
    ....
  51. ncbi request reprint Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 161:288-95. 2002
    ..A critical test of this hypothesis would be to determine if NT is involved in the expression of latent inhibition (LI), a psychophysiological and pharmacological model of schizophrenia...
  52. ncbi request reprint Polymorphisms of the glucocorticoid receptor gene and major depression
    Elisabeth F C van Rossum
    Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Biol Psychiatry 59:681-8. 2006
    ..The N363S and BclI polymorphisms have been associated with hypersensitivity to glucocorticoids, whereas the ER22/23EK polymorphism is related to glucocorticoid resistance...
  53. ncbi request reprint Changes in the hypothalamic-pituitary-adrenal axis and leptin levels during antidepressant treatment
    Hubertus Himmerich
    Max Planck Institut fur Psychiatrie, Munchen, Deutschland
    Neuropsychobiology 55:28-35. 2007
    ..Glucocorticoids themselves are reported to increase leptin synthesis and secretion in humans...
  54. pmc Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene
    Rebekah G Bradley
    Atlanta VA Medical Center, Georgia, USA
    Arch Gen Psychiatry 65:190-200. 2008
    ..Child abuse and trauma alter the endogenous stress response, principally corticotropin-releasing hormone and its downstream effectors, suggesting that a gene x environment interaction at this locus may be important in depression...
  55. pmc Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults
    Elisabeth B Binder
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia 30329, USA
    JAMA 299:1291-305. 2008
    ..Both genetic and environmental factors are contributory, with child abuse providing significant risk liability...
  56. ncbi request reprint Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression
    Johannes Schumacher
    Institute of Human Genetics, University of Bonn, Bonn
    Biol Psychiatry 58:307-14. 2005
    ....
  57. doi request reprint Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation
    Andreas Menke
    Am J Psychiatry 165:917-8. 2008
  58. ncbi request reprint Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs
    Elisabeth B Binder
    Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
    Neuropsychopharmacology 29:2200-7. 2004
    ..The effects of the NT receptor antagonist were paralleled by its effects on catalepsy in olanzapine--but not haloperidol--treated animals...

Research Grants1

  1. Peri-Partum Depression and Genetics of Glucocorticoid Receptor Regulating Genes
    Elisabeth Binder; Fiscal Year: 2007
    ..Such 'a priori' identification of women at risk will directly contribute to treatment planning and enhancement of perinatal health, obstetrical outcome, and infant well-being. ..