J L Arbiser

Summary

Affiliation: Emory University
Country: USA

Publications

  1. Arbiser J, Bonner M. Seborrheic Keratoses: The Rodney Dangerfield of Skin lesions, and Why They Should Get Our Respect. J Invest Dermatol. 2016;136:564-6 pubmed publisher
    ..The presence of wild type p53 (seborrheic keratosis) or mutant p53 (cutaneous squamous cell carcinoma) appears to dictate whether a lesion is sensitive to Akt inhibition or not. ..
  2. Costa A, Bonner M, Arbiser J. Use of Polyphenolic Compounds in Dermatologic Oncology. Am J Clin Dermatol. 2016;17:369-85 pubmed publisher
    ..This review evaluates the existing scientific literature in order to provide support for new research opportunities using polyphenolic compounds in oncodermatology. ..
  3. Mędra A, Witkowska M, Majchrzak A, Cebula Obrzut B, Bonner M, Robak T, et al. Pro-Apoptotic Activity of New Honokiol/Triphenylmethane Analogues in B-Cell Lymphoid Malignancies. Molecules. 2016;21: pubmed publisher
    ..In conclusion, some of the HAs are potent tumor-selective inducers of apoptosis in ex vivo CLL and in BL, DLBCL and MM cells in vitro. Further preclinical studies of these agents are recommended. ..
  4. Arbiser J, Gilbert L. Double Jeopardy: The Rubber Ball Bounces Twice. J Invest Dermatol. 2017;137:15-17 pubmed publisher
    ..This suggests that the remaining normal allele is required for the phenotype. Second, it suggests therapeutic approaches to treatment signal transduction inhibition. ..
  5. Arbiser J, Petros J, Klafter R, Govindajaran B, McLaughlin E, Brown L, et al. Reactive oxygen generated by Nox1 triggers the angiogenic switch. Proc Natl Acad Sci U S A. 2002;99:715-20 pubmed
    ..Nox1 induction of VEGF is eliminated by coexpression of catalase, indicating that hydrogen peroxide signals part of the switch to the angiogenic phenotype. ..
  6. request reprint
    Arbiser J, Bonner M, Berrios R. Hemangiomas, angiosarcomas, and vascular malformations represent the signaling abnormalities of pathogenic angiogenesis. Curr Mol Med. 2009;9:929-34 pubmed
    ..I hypothesize that hemangiomas, angiosarcomas, and vascular malformations represent the extremes of signaling abnormalities seen in pathogenic angiogenesis. ..
  7. Arbiser J, Nowak R, Michaels K, Skabytska Y, Biedermann T, Lewis M, et al. Evidence for biochemical barrier restoration: Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis. Sci Rep. 2017;7:11198 pubmed publisher
    ..Finally, they stimulated interleukin (IL)-12 production in skin dendritic cells. Thus suggesting barrier restoration has both a biochemical and physical component, and both are necessary for optimal barrier restoration. ..

Locale

Detail Information

Publications7

  1. Arbiser J, Bonner M. Seborrheic Keratoses: The Rodney Dangerfield of Skin lesions, and Why They Should Get Our Respect. J Invest Dermatol. 2016;136:564-6 pubmed publisher
    ..The presence of wild type p53 (seborrheic keratosis) or mutant p53 (cutaneous squamous cell carcinoma) appears to dictate whether a lesion is sensitive to Akt inhibition or not. ..
  2. Costa A, Bonner M, Arbiser J. Use of Polyphenolic Compounds in Dermatologic Oncology. Am J Clin Dermatol. 2016;17:369-85 pubmed publisher
    ..This review evaluates the existing scientific literature in order to provide support for new research opportunities using polyphenolic compounds in oncodermatology. ..
  3. Mędra A, Witkowska M, Majchrzak A, Cebula Obrzut B, Bonner M, Robak T, et al. Pro-Apoptotic Activity of New Honokiol/Triphenylmethane Analogues in B-Cell Lymphoid Malignancies. Molecules. 2016;21: pubmed publisher
    ..In conclusion, some of the HAs are potent tumor-selective inducers of apoptosis in ex vivo CLL and in BL, DLBCL and MM cells in vitro. Further preclinical studies of these agents are recommended. ..
  4. Arbiser J, Gilbert L. Double Jeopardy: The Rubber Ball Bounces Twice. J Invest Dermatol. 2017;137:15-17 pubmed publisher
    ..This suggests that the remaining normal allele is required for the phenotype. Second, it suggests therapeutic approaches to treatment signal transduction inhibition. ..
  5. Arbiser J, Petros J, Klafter R, Govindajaran B, McLaughlin E, Brown L, et al. Reactive oxygen generated by Nox1 triggers the angiogenic switch. Proc Natl Acad Sci U S A. 2002;99:715-20 pubmed
    ..Nox1 induction of VEGF is eliminated by coexpression of catalase, indicating that hydrogen peroxide signals part of the switch to the angiogenic phenotype. ..
  6. request reprint
    Arbiser J, Bonner M, Berrios R. Hemangiomas, angiosarcomas, and vascular malformations represent the signaling abnormalities of pathogenic angiogenesis. Curr Mol Med. 2009;9:929-34 pubmed
    ..I hypothesize that hemangiomas, angiosarcomas, and vascular malformations represent the extremes of signaling abnormalities seen in pathogenic angiogenesis. ..
  7. Arbiser J, Nowak R, Michaels K, Skabytska Y, Biedermann T, Lewis M, et al. Evidence for biochemical barrier restoration: Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis. Sci Rep. 2017;7:11198 pubmed publisher
    ..Finally, they stimulated interleukin (IL)-12 production in skin dendritic cells. Thus suggesting barrier restoration has both a biochemical and physical component, and both are necessary for optimal barrier restoration. ..