Mahul B Amin

Summary

Affiliation: Emory University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors
    Mahul B Amin
    Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mod Pathol 18:S131-45. 2005
  2. ncbi request reprint Key issues in reporting common cancer specimen findings using the College of American Pathologists cancer protocols
    Mahul B Amin
    Department of Surgical Pathology, Emory University Hospital, Atlanta, GA 30322 8110, USA
    Arch Pathol Lab Med 130:284-6. 2006
  3. ncbi request reprint An approach to the diagnosis of flat intraepithelial lesions of the urinary bladder using the World Health Organization/ International Society of Urological Pathology consensus classification system
    Mahul B Amin
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Adv Anat Pathol 9:222-32. 2002
  4. ncbi request reprint Prognostic impact of histologic subtyping of adult renal epithelial neoplasms: an experience of 405 cases
    Mahul B Amin
    Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Am J Surg Pathol 26:281-91. 2002
  5. ncbi request reprint Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications
    Adam Kuehn
    Department of Pathology, Emory University Hospital, Atlanta, GA, USA
    Am J Surg Pathol 31:1528-33. 2007
  6. doi request reprint A novel tumor grading scheme for chromophobe renal cell carcinoma: prognostic utility and comparison with Fuhrman nuclear grade
    Gladell P Paner
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 34:1233-40. 2010
  7. doi request reprint Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma
    Adeboye O Osunkoya
    Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Hum Pathol 40:206-10. 2009
  8. ncbi request reprint Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling
    Christopher D Hornsby
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Arch Pathol Lab Med 131:1541-6. 2007
  9. doi request reprint Diagnostic use of antibody to smoothelin in the recognition of muscularis propria in transurethral resection of urinary bladder tumor (TURBT) specimens
    Gladell P Paner
    Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, IL, USA
    Am J Surg Pathol 34:792-9. 2010
  10. doi request reprint ICUD-EAU International Consultation on Bladder Cancer 2012: Pathology
    Mahul B Amin
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Eur Urol 63:16-35. 2013

Detail Information

Publications88

  1. ncbi request reprint Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors
    Mahul B Amin
    Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mod Pathol 18:S131-45. 2005
    ....
  2. ncbi request reprint Key issues in reporting common cancer specimen findings using the College of American Pathologists cancer protocols
    Mahul B Amin
    Department of Surgical Pathology, Emory University Hospital, Atlanta, GA 30322 8110, USA
    Arch Pathol Lab Med 130:284-6. 2006
  3. ncbi request reprint An approach to the diagnosis of flat intraepithelial lesions of the urinary bladder using the World Health Organization/ International Society of Urological Pathology consensus classification system
    Mahul B Amin
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Adv Anat Pathol 9:222-32. 2002
    ....
  4. ncbi request reprint Prognostic impact of histologic subtyping of adult renal epithelial neoplasms: an experience of 405 cases
    Mahul B Amin
    Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Am J Surg Pathol 26:281-91. 2002
    ....
  5. ncbi request reprint Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications
    Adam Kuehn
    Department of Pathology, Emory University Hospital, Atlanta, GA, USA
    Am J Surg Pathol 31:1528-33. 2007
    ....
  6. doi request reprint A novel tumor grading scheme for chromophobe renal cell carcinoma: prognostic utility and comparison with Fuhrman nuclear grade
    Gladell P Paner
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 34:1233-40. 2010
    ....
  7. doi request reprint Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma
    Adeboye O Osunkoya
    Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Hum Pathol 40:206-10. 2009
    ..It may be necessary to identify additional biomarkers to include with claudin-7 and claudin-8 in a larger immunohistochemical panel to improve diagnostic sensitivity and specificity...
  8. ncbi request reprint Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling
    Christopher D Hornsby
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Arch Pathol Lab Med 131:1541-6. 2007
    ..Immunohistochemistry is useful for distinguishing chromophobe RCC from other subtypes of renal carcinoma, but no expression marker reliably separates chromophobe RCC from oncocytoma...
  9. doi request reprint Diagnostic use of antibody to smoothelin in the recognition of muscularis propria in transurethral resection of urinary bladder tumor (TURBT) specimens
    Gladell P Paner
    Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, IL, USA
    Am J Surg Pathol 34:792-9. 2010
    ....
  10. doi request reprint ICUD-EAU International Consultation on Bladder Cancer 2012: Pathology
    Mahul B Amin
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Eur Urol 63:16-35. 2013
    ..To present a summary of the 2nd International Consultation on Bladder Cancer recommendations on the pathology of bladder cancer using an evidence-based strategy...
  11. doi request reprint Grading of invasive cribriform carcinoma on prostate needle biopsy: an interobserver study among experts in genitourinary pathology
    Mathieu Latour
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 32:1532-9. 2008
    ..In conclusion, most of the small cribriform cancer foci seen on needle biopsy should be interpreted as Gleason pattern 4 and not pattern 3...
  12. ncbi request reprint Renal epithelial neoplasms: diagnostic applications of gene expression profiling
    Andrew N Young
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine Grady Memorial Hospital, 80 Jesse Hill Jr Drive SE, Atlanta, GA 30303, USA
    Adv Anat Pathol 15:28-38. 2008
    ..Here, we review clinical features of kidney cancer, the WHO classification system, and the growing role of molecular classification for diagnosis, prognosis, and therapy of this disease...
  13. ncbi request reprint Further characterization of the muscle layers and lamina propria of the urinary bladder by systematic histologic mapping: implications for pathologic staging of invasive urothelial carcinoma
    Gladell P Paner
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Surg Pathol 31:1420-9. 2007
    ....
  14. doi request reprint Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma
    Mahul B Amin
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:384-92. 2009
    ..In light of the distinctive clinicopathologic features and a low but definite metastatic potential, this unique subtype of renal cell carcinoma deserves formal recognition in the contemporary classification of renal neoplasms...
  15. doi request reprint Primary thyroid-like follicular carcinoma of the kidney: report of 6 cases of a histologically distinctive adult renal epithelial neoplasm
    Mahul B Amin
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:393-400. 2009
    ..Thyroid-like follicular renal cell carcinoma represents a unique histologic subtype of renal cell carcinoma of low malignant potential and its primary importance is to distinguish it from metastatic carcinoma from the thyroid...
  16. ncbi request reprint Urothelial neoplasms in patients 20 years or younger: a clinicopathological analysis using the world health organization 2004 bladder consensus classification
    Samson W Fine
    Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Urol 174:1976-80. 2005
    ..Urothelial neoplasms in patients younger than 20 years are rare, with conflicting data regarding clinical outcomes...
  17. ncbi request reprint Cancer-specific loss of beta-defensin 1 in renal and prostatic carcinomas
    Carlton D Donald
    Department of Urology, Emory University School of Medicine, Atlanta, Georgia, USA
    Lab Invest 83:501-5. 2003
    ..We have thus demonstrated the cancer-specific down-regulation of DEFB1 in a large sample of prostatic and renal carcinomas and validated one of the key findings of previous cancer gene profiling studies of prostatic and renal neoplasia...
  18. doi request reprint Diagnostic utility of antibody to smoothelin in the distinction of muscularis propria from muscularis mucosae of the urinary bladder: a potential ancillary tool in the pathologic staging of invasive urothelial carcinoma
    Gladell P Paner
    Department of Pathology, Urology, Loyola University Medical Center, Maywood, IL, USA
    Am J Surg Pathol 33:91-8. 2009
    ....
  19. ncbi request reprint Immunohistochemical analysis of mucinous tubular and spindle cell carcinoma and papillary renal cell carcinoma of the kidney: significant immunophenotypic overlap warrants diagnostic caution
    Gladell P Paner
    Department of Pathology, Emory University Hospital, 1364 Clifton Road NE, G 167, Atlanta, GA 30322, USA
    Am J Surg Pathol 30:13-9. 2006
    ....
  20. ncbi request reprint Basal cell proliferations of the prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 cases, including four carcinomas, with a proposed classification
    Jesse K McKenney
    Department of Pathology, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, GA 30322, USA
    Am J Surg Pathol 28:1289-98. 2004
    ..This study suggests that adenoid cystic carcinomas are biologically indolent following prostatectomy but have a low risk of distant metastasis...
  21. doi request reprint A contemporary update on pathology reporting for prostate cancer: biopsy and radical prostatectomy specimens
    Samson W Fine
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Eur Urol 62:20-39. 2012
    ..The diagnosis of and reporting parameters for prostate cancer (PCa) have evolved over time, yet they remain key components in predicting clinical outcomes...
  22. ncbi request reprint Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma: clinicopathologic analysis of 52 cases of rare aggressive subtypes of renal cell carcinoma with a focus on their interrelationship
    Ruta Gupta
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 36:1265-78. 2012
    ..The extremely poor prognosis and ongoing clinical trials with specific therapeutic protocols argue for their accurate distinction from other renal cell carcinoma subtypes...
  23. pmc Frequency and determinants of disagreement and error in gleason scores: a population-based study of prostate cancer
    Michael Goodman
    Department of Epidemiology, Emory University Rollins School of Public Health, 1518 Clifton Road, NE Atlanta, GA 30322, USA
    Prostate 72:1389-98. 2012
    ..To examine factors that affect accuracy and reliability of prostate cancer grade we compared Gleason scores documented in pathology reports and those assigned by urologic pathologists in a population-based study...
  24. ncbi request reprint Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma
    Sanjay Logani
    Emory University School of Medicine, Atlanta, GA, USA
    Mod Pathol 18:19-25. 2005
    ..Diffuse expression of all three markers (CDX2, beta-catenin and P504S) in a tumor in the ovary was found to be virtually diagnostic of metastasis from a colorectal primary in this study...
  25. ncbi request reprint Update on the Gleason grading system for prostate cancer: results of an international consensus conference of urologic pathologists
    Jonathan I Epstein
    Department of Pathology, Urology and Oncology, The Johns Hopkins Hospital, Weinberg Building Rm 2242, Baltimore, MD 21231, USA
    Adv Anat Pathol 13:57-9. 2006
    ..This article serves as a brief overview and summary of the proceedings that have been published in detail in recent literature...
  26. ncbi request reprint Current trends in molecular classification of adult renal tumors
    Andrew N Young
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
    Urology 67:873-80. 2006
  27. doi request reprint Interobserver reproducibility in the diagnosis of invasive micropapillary carcinoma of the urinary tract among urologic pathologists
    Ankur R Sangoi
    Department of Pathology, Stanford University, Stanford, CA, USA
    Am J Surg Pathol 34:1367-76. 2010
    ..These findings suggest that more study of IMPC is needed to identify the individual pathologic features that might potentially correlate with an aggressive outcome and response to intravesical therapy...
  28. doi request reprint Rhabdomyosarcoma of the urinary bladder in adults: predilection for alveolar morphology with anaplasia and significant morphologic overlap with small cell carcinoma
    Gladell P Paner
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 32:1022-8. 2008
    ....
  29. doi request reprint Chromophobe renal cell carcinoma: histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 145 cases
    Mahul B Amin
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 32:1822-34. 2008
    ..The adverse presence of these features in a nephrectomy specimen with chromophobe RCC warrants active surveillance, and these patients may be candidates for adjuvant therapies as they become available...
  30. ncbi request reprint Loss of HOXC6 expression induces apoptosis in prostate cancer cells
    Sumathi Ramachandran
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Oncogene 24:188-98. 2005
    ..Our data suggest that HOXC6 may be a novel potential therapeutic target for prostate cancer...
  31. pmc Molecular classification of renal tumors by gene expression profiling
    Audrey N Schuetz
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Decatur, GA 30033, USA
    J Mol Diagn 7:206-18. 2005
    ..In summary, renal tumor subtypes were classified by distinct gene expression profiles, illustrating tumor pathobiology and translating into novel molecular bioassays using fixed tissue...
  32. doi request reprint Diagnostic implications of transcription factor Pax 2 protein and transmembrane enzyme complex carbonic anhydrase IX immunoreactivity in adult renal epithelial neoplasms
    Ruta Gupta
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:241-7. 2009
    ..These antibodies may reliably discriminate between clinically significant subtypes of RCC with overlapping cytoarchitectural features...
  33. ncbi request reprint Current trends in the molecular classification of renal neoplasms
    Andrew N Young
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
    ScientificWorldJournal 6:2505-18. 2006
    ..Here, we review clinical features of kidney cancer, the WHO classification system, and the growing role of molecular classification for diagnosis, prognosis, and therapy of this disease...
  34. doi request reprint Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases
    Jeffrey G Brown
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 34:942-9. 2010
    ....
  35. doi request reprint Neoplasms of the upper urinary tract: a review with focus on urothelial carcinoma of the pelvicalyceal system and aspects related to its diagnosis and reporting
    Ruta Gupta
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Adv Anat Pathol 15:127-39. 2008
    ..This review focuses on urothelial carcinoma of the upper tract highlighting issues related to its diagnosis, staging, and reporting...
  36. doi request reprint Utility of a comprehensive immunohistochemical panel in the differential diagnosis of spindle cell lesions of the urinary bladder
    Danielle E Westfall
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:99-105. 2009
    ....
  37. ncbi request reprint The role of immunohistochemistry in the diagnosis of urinary bladder neoplasms
    Jesse K McKenney
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, USA
    Semin Diagn Pathol 22:69-87. 2005
    ....
  38. ncbi request reprint Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia
    Satish K Tickoo
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 30:141-53. 2006
    ..Acquired cystic disease-associated RCC is the commonest tumor subtype in ESRD, and biologically it appears to be more aggressive than the other tumor subtypes in ESRD...
  39. ncbi request reprint Immunoprofile of ovarian tumors with putative transitional cell (urothelial) differentiation using novel urothelial markers: histogenetic and diagnostic implications
    Sanjay Logani
    Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Am J Surg Pathol 27:1434-41. 2003
    ..They also indicate that the morphologic similarity between TCC-O and TCC-B does not indicate any histogenic similarity and, as others have noted, TCC-O is a variant morphology in the spectrum of surface epithelial carcinomas...
  40. doi request reprint Influence of Histologic Criteria and Confounding Factors in Staging Equivocal Cases for Microscopic Perivesical Tissue Invasion (pT3a): An Interobserver Study Among Genitourinary Pathologists
    Vijayalakshmi Ananthanarayanan
    Department of Pathology, University of Chicago, Chicago, IL Department of Biostatistics and Bioinformatics, Rollins School of Public Health Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN Department of Pathology, Johns Hopkins Hospital, Baltimore, MD Department of Pathology, University of California, San Diego, CA Division of Anatomic Pathology, Mayo Clinic, Rochester, MN Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH Department of Pathology, Massachusetts General Hospital, Boston, MA Department of Pathology, MD Anderson Cancer Center Department of Pathology, Methodist Hospital, Houston, TX Department of Pathology, Memorial Sloan Kettering Cancer Center, New York Department of Pathology, University of Rochester Medical Center, Rochester, NY Section of Pathological Anatomy, Polytechnic University of the Marche Region, Ancona, Italy Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada Department of Pathology, Nagoya Daini Red Cross Hospital, Nagoya
    Am J Surg Pathol 38:167-75. 2014
    ..This study highlights the need to adopt common criteria in defining the outer MP boundary. Future studies may identify the most clinically relevant histoanatomic criteria for MPVTI. ..
  41. doi request reprint KRAS mutation testing in human cancers: The pathologist's role in the era of personalized medicine
    Hanlin L Wang
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Adv Anat Pathol 17:23-32. 2010
    ..Guidelines for KRAS testing that address these and other important points of consideration have recently been proposed in the United States and the European Union...
  42. doi request reprint Plasmacytoid urothelial carcinoma: detailed analysis of morphology with clinicopathologic correlation in 17 cases
    Priya Nigwekar
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:417-24. 2009
    ..Distinction from metastatic carcinoma from other primary sites such as stomach and breast is critical due to differing therapeutic implications...
  43. ncbi request reprint Surgical margin and Gleason score as predictors of postoperative recurrence in prostate cancer with or without chromosome 8p allelic imbalance
    Wei Zhou
    Department of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, 1365 Clifton Road NE, Atlanta, GA 30322, USA
    Prostate 61:81-91. 2004
    ..Existing pathological markers can predict disease recurrence only to a certain extent, and there is a need for more accurate predictors...
  44. doi request reprint Renal cell carcinoma: assessment of key pathologic prognostic parameters and patient characteristics in 47,909 cases using the National Cancer Data Base
    Nalan Nese
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Ann Diagn Pathol 13:1-8. 2009
    ....
  45. doi request reprint Pseudomyxoma peritonei associated with primary mucinous borderline tumor of the renal pelvicalyceal system
    Priya Rao
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Arch Pathol Lab Med 133:1472-6. 2009
    ..This case illustrates that, in a patient with pseudomyxoma peritonei, the absence of an appendiceal, gastrointestinal, or ovarian primary tumor raises the possibility of a primary neoplasm at an unusual site such as the kidney...
  46. doi request reprint A contemporary update on pathology standards for bladder cancer: transurethral resection and radical cystectomy specimens
    Donna E Hansel
    Department of Pathology, Cleveland Clinic, Cleveland, OH, USA
    Eur Urol 63:321-32. 2013
    ..Pathology standards for the diagnosis of bladder cancer (BCa) have recently evolved to better reflect patient diagnosis and clinical outcomes...
  47. ncbi request reprint Colonic adenocarcinoma metastatic to the urinary tract versus primary tumors of the urinary tract with glandular differentiation: a report of 7 cases and investigation using a limited immunohistochemical panel
    Pheroze Tamboli
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Arch Pathol Lab Med 126:1057-63. 2002
    ....
  48. doi request reprint Best practice in diagnostic immunohistochemistry: prostate carcinoma and its mimics in needle core biopsies
    Gladell P Paner
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Arch Pathol Lab Med 132:1388-96. 2008
    ..The availability of prostate cancer-associated and basal cell-associated markers has been an invaluable addition to diagnostic surgical pathology...
  49. ncbi request reprint Beta defensin-1, parvalbumin, and vimentin: a panel of diagnostic immunohistochemical markers for renal tumors derived from gene expression profiling studies using cDNA microarrays
    Andrew N Young
    Department of Pathology, Emory University, Atlanta, Georgia, USA
    Am J Surg Pathol 27:199-205. 2003
    ..This work demonstrates that a useful panel of immunohistochemical markers can be derived from differential gene expression profiles determined using cDNA microarrays...
  50. ncbi request reprint Morphologic criteria for the diagnosis of prostatic adenocarcinoma in needle biopsy specimens. A study of 250 consecutive cases in a routine surgical pathology practice
    Murali Varma
    Department of Pathology, Henry Ford Hospital, Detroit, Mich, USA
    Arch Pathol Lab Med 126:554-61. 2002
    ..The few reports dealing with diagnostic criteria of cancer in needle biopsies have been largely confined to analysis of selected cases that posed particular diagnostic difficulty...
  51. ncbi request reprint Alveolar soft-part sarcoma of the urinary bladder with urethral recurrence: a unique case with emphasis on differential diagnoses and diagnostic utility of an immunohistochemical panel including TFE3
    Mahul B Amin
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
    Am J Surg Pathol 30:1322-5. 2006
    ....
  52. doi request reprint Rete testis-associated nodular steroid cell nests: description of putative pluripotential testicular hilus steroid cells
    Gladell P Paner
    Department of Pathology, University of Chicago, Chicago, IL, USA
    Am J Surg Pathol 35:505-11. 2011
    ..We propose to name these proliferations rete testis-associated nodular steroid cell nests...
  53. doi request reprint Pure epithelioid PEComas (so-called epithelioid angiomyolipoma) of the kidney: A clinicopathologic study of 41 cases: detailed assessment of morphology and risk stratification
    Nalan Nese
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 35:161-76. 2011
    ..009 and 0.033, respectively). Our data of a large series with uniform definitional criteria confirm the malignant potential for pure epithelioid PEComas and provide adverse prognostic parameters for risk stratification in these patients...
  54. doi request reprint Non-epithelial neoplasms of the prostate
    Gladell P Paner
    Department of Pathology, University of Chicago, Chicago, IL, USA
    Histopathology 60:166-86. 2012
    ..This review addresses and updates the clinicopathological features of the entire spectrum of non-epithelial tumours with an approach to the histological diagnosis...
  55. ncbi request reprint Mutations in the von Hippel-Lindau (VHL) gene refine differential diagnostic criteria in renal cell carcinoma
    Nandita Barnabas
    Department of Pathology, Henry Ford Health System, Detroit, Michigan 48202, USA
    J Surg Oncol 80:52-60. 2002
    ..The objective of this study was to determine if mutations in the VHL gene can serve as auxiliary diagnostic criteria in refining histology based subtyping of renal epithelial neoplasia...
  56. pmc Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis
    Shian Ying Sung
    Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 68:9996-10003. 2008
    ..These observations collectively suggest coevolution of cancer and stromal cells occurred under three-dimensional growth condition, which ultimately accelerates cancer growth and metastasis...
  57. ncbi request reprint Carcinoma in situ of the urinary bladder: review of clinicopathologic characteristics with an emphasis on aspects related to molecular diagnostic techniques and prognosis
    Nalan Nese
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Natl Compr Canc Netw 7:48-57. 2009
    ..From a clinical perspective, the principal determinants of outcome are extent of disease, involvement of prostatic urethra, response to therapy, and time to recurrence...
  58. ncbi request reprint Urothelial (transitional cell) papilloma of the urinary bladder: a clinicopathologic study of 26 cases
    Jesse K McKenney
    Department of Pathology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Mod Pathol 16:623-9. 2003
    ..Urothelial papillomas are histologically and probably biologically distinctive tumors and merit distinction from other higher risk papillary neoplasms of the urinary bladder...
  59. ncbi request reprint The morphologic spectrum of metastatic prostatic adenocarcinoma to the lung: special emphasis on histologic features overlapping with other pulmonary neoplasms
    John N Copeland
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
    Am J Clin Pathol 117:552-7. 2002
    ..Attention to specific discriminating histologic features, supported by immunohistochemical staining, may be useful in the differential diagnosis, which is therapeutically and prognostically critical...
  60. doi request reprint Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid change
    Jasreman Dhillon
    Department of Surgical Pathology, Winthrop University Hospital, Mineola, NY 11501, USA
    Am J Surg Pathol 33:44-9. 2009
    ..Distinction of the sarcomatoid histology from inherent spindle cell component of mucinous tubular and spindle cell carcinoma is important because of its unfavorable prognostic implication...
  61. pmc mtDNA mutations increase tumorigenicity in prostate cancer
    John A Petros
    Department of Urology, Emory University, 1365A Clifton Road, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 102:719-24. 2005
    ..The mutant tumors also generated significantly more ROS. Therefore, mtDNA mutations do play an important role in the etiology of prostate cancer...
  62. ncbi request reprint Utility of alpha-methylacyl coenzyme A racemase (p504s antibody) as a diagnostic immunohistochemical marker for cancer
    Aziza Nassar
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Appl Immunohistochem Mol Morphol 13:252-5. 2005
    ..It may be a useful adjunct to an immunohistochemical panel employed in the differential diagnosis of colon versus ovarian and breast carcinoma; the latter two infrequently express AMACR...
  63. doi request reprint The many faces of urothelial carcinoma: an update with an emphasis on recently described variants
    Priya Nigwekar
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Adv Anat Pathol 15:218-33. 2008
    ..This review also includes a discussion on variants on which there is recent information available...
  64. ncbi request reprint Osteoclast-rich undifferentiated carcinomas of the urinary tract
    Dilek Baydar
    Department of Pathology, The Johns Hopkins University School of Medicine, The James Brady Urological Institute, The Johns Hospital, Baltimore, MD 21231, USA
    Mod Pathol 19:161-71. 2006
    ....
  65. ncbi request reprint Pseudosarcomatous myofibroblastic proliferations of the bladder: a clinicopathologic study of 42 cases
    Lara R Harik
    Department of Pathology and Laboratory Medicine, Emory University Hospital, 1364 Clifton Road NE, Atlanta, GA 30322, USA
    Am J Surg Pathol 30:787-94. 2006
    ..Despite the Alk-1 gene translocation, there continues to be sufficient evidence for regarding these as distinct from the so-called inflammatory myofibroblastic tumor of childhood...
  66. ncbi request reprint Updated protocol for the examination of specimens from patients with carcinoma of the urinary bladder, ureter, and renal pelvis
    Mahul B Amin
    Department of Pathology, Emory University Hospital, Atlanta, GA, USA
    Arch Pathol Lab Med 127:1263-79. 2003
  67. pmc Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells?
    So Dug Lim
    Department of Urology, Emory University School of Medicine, and Atlanta VA Medical Center, Georgia 30322, USA
    Mol Med 13:160-5. 2007
    ..These results support a novel histogenesis of angiomyolipoma as a defect in differentiation of stem cell precursors...
  68. doi request reprint Comparative analysis of size estimation by mapping and counting number of blocks with ductal carcinoma in situ in breast excision specimens
    Farnaz Dadmanesh
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Arch Pathol Lab Med 133:26-30. 2009
    ..The size of ductal carcinoma in situ (DCIS) is a significant predictor of local tumor recurrence and is used for selection of patients for conservative versus aggressive therapy. A standardized method for size assessment is lacking...
  69. doi request reprint Robot-assisted radical prostatectomy: current evaluation of surgical margins in clinically low-, intermediate-, and high-risk prostate cancer
    David S Yee
    Department of Urology, University of California, Irvine Medical Center, Orange, California, USA
    J Endourol 23:1461-5. 2009
    ..We report our PSM rates in our most current 500 cases and particularly in clinically high-risk disease...
  70. ncbi request reprint The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma
    Jonathan I Epstein
    Department of Pathology, Urology and Oncology, Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 29:1228-42. 2005
  71. ncbi request reprint Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney: a clinicopathologic and immunohistochemical analysis of 11 cases
    Rafael E Jimenez
    Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Surg Pathol 26:320-7. 2002
    ..The accurate distinction between these two entities has clear prognostic and therapeutic implications...
  72. ncbi request reprint Potential utility of uroplakin III, thrombomodulin, high molecular weight cytokeratin, and cytokeratin 20 in noninvasive, invasive, and metastatic urothelial (transitional cell) carcinomas
    Douglas C Parker
    Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Surg Pathol 27:1-10. 2003
    ..The results of the study indicate a role for an antibody panel that includes UROIII, THR, HMWCK, and CK20 in the diagnosis of urothelial tumors...
  73. ncbi request reprint Intratubular large cell hyalinizing sertoli cell neoplasia of the testis: a report of 8 cases of a distinctive lesion of the Peutz-Jeghers syndrome
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 31:827-35. 2007
    ..Orchiectomy is indicated when there is evidence of an invasive tumor and may be necessary to control hormonal manifestations...
  74. ncbi request reprint Prognostic role of CD44 cell adhesion molecule expression in primary and metastatic renal cell carcinoma: a clinicopathologic study of 125 cases
    So Dug Lim
    Department of Pathology, Konkuk University School of Medicine, Gwangjin gu, Seoul, Republic of Korea
    Virchows Arch 452:49-55. 2008
    ..Our study suggests that CD44 status in RCC provides useful prognostic information both in primary and metastatic RCCs and may have applicability in stratifying patients for therapeutic decisions...
  75. ncbi request reprint Expression of epithelial cell adhesion molecule (EpCam) in renal epithelial tumors
    Philip Went
    Institute of Pathology, University of Basel, Basel, Switzerland
    Am J Surg Pathol 29:83-8. 2005
    ..The data suggest EpCam as a potential therapeutic target in a subset of patients with RCC. In addition, expression patterns of EpCam could become a helpful tool in the discrimination of chromophobe RCC and oncocytoma...
  76. ncbi request reprint Protocol for the examination of specimens from patients with Wilms tumor (nephroblastoma) or other renal tumors of childhood
    Stephen J Qualman
    Department of Laboratory Medicine, Children s Hospital, Columbus, Ohio 43205, USA
    Arch Pathol Lab Med 127:1280-9. 2003
  77. ncbi request reprint Updated protocol for the examination of specimens from patients with carcinomas of the prostate gland
    John R Srigley
    Department of Laboratory Medicine, Credit Valley Hospital, Mississauga, Ontario, Canada
    Arch Pathol Lab Med 130:936-46. 2006
  78. ncbi request reprint An immunohistochemical approach to the differential diagnosis of renal tumors
    Brian F Skinnider
    Department of Pathology, Vancouver General Hospital and University of British Columbia, Canada
    Semin Diagn Pathol 22:51-68. 2005
    ....
  79. ncbi request reprint The role of tissue microarrays in prostate cancer biomarker discovery
    Milton W Datta
    Hospital Pathology Associates, Abbott Northwestern Hospital, University of Minnesota, Minneapolis, MN 55407, USA
    Adv Anat Pathol 14:408-18. 2007
    ..The processes used here can be applied to any tumor type to improve patient diagnosis, prognosis, and treatment response prediction...
  80. pmc Relevance of nuclear and cytoplasmic von hippel lindau protein expression for renal carcinoma progression
    Peter Schraml
    Institute of Pathology, University Hospital, University of Basel, Schonbeinstrasse 40, 4031 Basel, Switzerland
    Am J Pathol 163:1013-20. 2003
    ..0001), early tumor stage (P < 0.01), and better prognosis (P < 0.01). These results imply that alteration of subcellular pVHL trafficking is of potential relevance for the biological behavior of clear-cell RCC...
  81. ncbi request reprint Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term
    Julia Turbiner
    Pathology Department, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 31:489-500. 2007
    ....
  82. doi request reprint Interobserver variability between expert urologic pathologists for extraprostatic extension and surgical margin status in radical prostatectomy specimens
    Andrew J Evans
    Department of Pathology and Laboratory Medicine, University Health Network, Toronto, Ontario, Canada
    Am J Surg Pathol 32:1503-12. 2008
    ..Interobserver variability for EPE and SM interpretation was principally related to the lack of a clearly definable prostatic capsule and crush/thermal artifact along the edge of the gland, respectively...
  83. ncbi request reprint Genetic subtyping of renal cell carcinoma by comparative genomic hybridization
    Kerstin Junker
    Department of Urology, Friedrich Schiller University, 07743 Jena, Germany
    Recent Results Cancer Res 162:169-75. 2003
    ..The definition of genetic alterations seems helpful for a tumor typing especially when morphology is equivocal. Therefore, genetic analyses represent a powerful diagnostic and prognostic tool for RCC...
  84. ncbi request reprint Polyclonal anti-PSA is more sensitive but less specific than monoclonal anti-PSA: Implications for diagnostic prostatic pathology
    Murali Varma
    Department of Pathology, University Hospital of Wales, Cardiff
    Am J Clin Pathol 118:202-7. 2002
    ..Sections of high-grade prostate cancer should be included as positive controls for PSA immunostaining...
  85. ncbi request reprint Clear cell carcinoma of the urinary bladder: a report and comparison of four tumors of mullerian origin and nine of probable urothelial origin with discussion of histogenesis and diagnostic problems
    Esther Oliva
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Fruit Street, Boston, MA 02114, USA
    Am J Surg Pathol 26:190-7. 2002
    ....
  86. ncbi request reprint Expression of alpha-methylacyl-CoA racemase (P504S) in nephrogenic adenoma: a significant immunohistochemical pitfall compounding the differential diagnosis with prostatic adenocarcinoma
    Brian F Skinnider
    Department of Pathology, Vancouver Hospital and Health Sciences Center and University of British Columbia, Vancouver, BC, Canada
    Am J Surg Pathol 28:701-5. 2004
    ....
  87. ncbi request reprint Distribution of cytokeratins and vimentin in adult renal neoplasms and normal renal tissue: potential utility of a cytokeratin antibody panel in the differential diagnosis of renal tumors
    Brian F Skinnider
    Department of Pathology, Vancouver General Hospital and University of British Columbia, Vancouver, British Columbia, Canada
    Am J Surg Pathol 29:747-54. 2005
    ..In conclusion, CK expression patterns may be helpful in several differential diagnostic situations when dealing with adult RENs...
  88. doi request reprint Squamous differentiation in a sarcomatoid chromophobe renal cell carcinoma: an unusual case report with review of the literature
    Seethalakshmi Viswanathan
    Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Arch Pathol Lab Med 132:1672-4. 2008
    ..The renal pelvis was smooth walled and uninvolved. Kidney-specific cadherin was positive in the chromophobe renal cell carcinoma areas and negative in the sarcomatoid and squamous areas...