Research Topics
Genomes and GenesSpecies | Amy L AdamsSummaryAffiliation: Emory University Country: USA Publications
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Publications
Commonly encountered dilemmas in breast cancer reporting and stagingAmy L Adams
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Semin Diagn Pathol 29:109-15. 2012....
Histologic grading of invasive lobular carcinoma: does use of a 2-tiered nuclear grading system improve interobserver variability?Amy L Adams
Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
Ann Diagn Pathol 13:223-5. 2009..For ILC, where use of the NHG places substantial weight on nuclear pleomorphism, a 2-tiered nuclear grading system may reduce interobserver variability yet still provide useful prognostic information...
Using a higher cutoff for the percentage of HER2+ cells decreases interobserver variability in the interpretation of HER2 immunohistochemical analysisOmar Hameed
Department of Pathology, University of Alabama School of Medicine, Birmingham, AL 35294 6823, USA
Am J Clin Pathol 130:425-7. 2008..001 for all comparisons). Using a 30% cutoff for the percentage of HER2+ cells by immunohistochemical analysis modestly decreased interobserver variability in the interpretation of HER2 immunohistochemical results...
The effect of neoadjuvant chemotherapy on histologic grade, hormone receptor status, and HER2/neu status in breast carcinomaAmy L Adams
Department of Pathology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
Breast J 14:141-6. 2008..No significant changes were noted for the degree of tubule formation, nuclear pleomorphism, overall Bloom-Richardson score, and hormone receptor status. However, small sample size may be a limitation of these results...
Negative colposcopic biopsy after positive human papilloma virus (HPV) DNA testing: false-positive HPV results or false-negative histologic findings?Amy L Adams
Department of Pathology, University of Alabama at Birmingham, USA
Am J Clin Pathol 125:413-8. 2006..Additional levels should be obtained for discrepant results. Close follow-up is crucial when the initial biopsy result is negative because a small number of patients will have squamous abnormalities in subsequent studies...
Effect of storage on p63 immunohistochemistry: a time-course studyHolly N Burford
Department of Pathology, University of Alabama School of Medicine, Birmingham, AL 35294 6823, USA
Appl Immunohistochem Mol Morphol 17:68-71. 2009..This should be considered in the evaluation of p63 immunostains performed on stored unstained sections, both in diagnostic surgical pathology and in translational research studies...
Proliferation (Ki-67 and phosphohistone H3) and oncotype DX recurrence score in estrogen receptor-positive breast cancerDaron J Williams
School of Medicine, Emory University, Atlanta, GA, USA
Appl Immunohistochem Mol Morphol 19:431-6. 2011..This observation suggests that immunohistochemical assessment of markers of proliferation may provide useful prognostic information, at lower cost than RS testing...
Luminal cytokeratin expression profiles of breast papillomas and papillary carcinomas and the utility of a cytokeratin 5/p63/cytokeratin 8/18 antibody cocktail in their distinctionEmily S Reisenbichler
Department of Pathology, University of Alabama at Birmingham, 35294 6823, USA
Mod Pathol 24:185-93. 2011....
Attenuated podoplanin staining in breast myoepithelial cells: a potential caveat in the diagnosis of lymphatic invasionZhaohai Yang
Department of Pathology, University of Alabama, Birmingham, AL 35294 6823, USA
Appl Immunohistochem Mol Morphol 17:425-30. 2009....
Does using a higher cutoff for the percentage of positive cells improve the specificity of HER-2 immunohistochemical analysis in breast carcinoma?Omar Hameed
Department of Pathology, University of Alabama School of Medicine, Birmingham 35294 6823, USA
Am J Clin Pathol 128:825-9. 2007..These findings seem to somehow support the recently proposed American Society of Clinical Oncology/College of American Pathologists guideline recommendations for HER-2 testing; nevertheless further studies are suggested...
Nottingham-defined mitotic score: comparison with visual and image cytometric phosphohistone H3 labeling indices and correlation with Oncotype DX recurrence scoreBlazej Zbytek
Department of Pathology and Laboratory Medicine, University of Tennessee Health Science Center, Memphis, TN, USA
Appl Immunohistochem Mol Morphol 21:48-53. 2013..30) and between visual PPH3 mitotic score and RS (P<0.001, Spearman coefficient 0.28). In conclusion, mitotic score by any of the 3 methods studied may be useful in assessing tumor grade, proliferation, and prognosis...
Acidophilic nuclear inclusions are specific for florid ductal hyperplasia among proliferative breast lesionsScott Lauer
Department of Pathology, Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Arch Pathol Lab Med 135:766-9. 2011..These correlated ultrastructurally with so-called helioid inclusions. However, there since has been little discussion of these inclusions in the literature...
Clinical significance of unsatisfactory conventional pap smears owing to inadequate squamous cellularity defined by the Bethesda 2001 criterionAmy L Adams
Department of Pathology, University of Alabama at Birmingham, 35249-6823, USA
Am J Clin Pathol 123:738-43. 2005....
