Research Topics
| T AbshireSummaryAffiliation: Emory University Country: USA Publications
| Collaborators |
Detail Information
Publications
Sucrose formulated recombinant human antihemophilic factor VIII is safe and efficacious for treatment of hemophilia A in home therapy--International Kogenate-FS Study GroupT C Abshire
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
Thromb Haemost 83:811-6. 2000..Overall, rFVIII-FS provided excellent hemostatic control, was well-tolerated, and caused no significant adverse effects, thus demonstrating safety and efficacy for treatment of bleeds in patients with hemophilia A...
Recombinant factor VIIa: review of efficacy, dosing regimens and safety in patients with congenital and acquired factor VIII or IX inhibitorsT Abshire
Aflac Cancer Center and Blood Disorders Service, Emory University, Atlanta, GA 30322, USA
J Thromb Haemost 2:899-909. 2004..Additionally, thrombotic events have not increased despite a growing experience with higher dosing of rFVIIa...
Safety update on the use of recombinant factor VIIa and the treatment of congenital and acquired deficiency of factor VIII or IX with inhibitorsT Abshire
Aflac Cancer Center and Blood Disorders Service, Emory University, Atlanta, GA, USA
Haemophilia 14:898-902. 2008..However, use of rFVIIa for off-label indications should continue to be monitored closely via clinical trials and carefully designed registries...
Sites of initial bleeding episodes, mode of delivery and age of diagnosis in babies with haemophilia diagnosed before the age of 2 years: a report from The Centers for Disease Control and Prevention's (CDC) Universal Data Collection (UDC) projectR Kulkarni
Division of Blood Disorders, Centers for Disease Control and Prevention, Atlanta, GA, USA
Haemophilia 15:1281-90. 2009..This study highlights the significant rate and the sites of initial bleeding unique to very young children with haemophilia and underscores the need for research to identify optimal evidence-based recommendations for their management...
Leukemia and P32 radionuclide synovectomy for hemophilic arthropathyA L Dunn
J Thromb Haemost 3:1541-2. 2005
Incidence of inhibitors in a cohort of 838 males with hemophilia A previously treated with factor VIII concentratesC L Kempton
Aflac Cancer Center and Blood Disorders Service, Emory University, Atlanta, GA, USA
J Thromb Haemost 4:2576-81. 2006..Understanding the baseline rate of inhibitor development in the population of previously treated patients (PTPs) is important when evaluating the effect of exposure to new factor replacement products on inhibitor formation...
