Robert W Baker

Summary

Affiliation: Eli Lilly and Company
Country: USA

Publications

  1. pmc Clinical, functional, and economic ramifications of early nonresponse to antipsychotics in the naturalistic treatment of schizophrenia
    Haya Ascher-Svanum
    Eli Lilly and Company, Indianapolis, IN 46285, USA
    Schizophr Bull 34:1163-71. 2008
  2. ncbi request reprint Efficacy of olanzapine combined with valproate or lithium in the treatment of dysphoric mania
    Robert W Baker
    Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Br J Psychiatry 185:472-8. 2004
  3. ncbi request reprint Effectiveness of rapid initial dose escalation of up to forty milligrams per day of oral olanzapine in acute agitation
    Robert W Baker
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285
    J Clin Psychopharmacol 23:342-8. 2003
  4. ncbi request reprint Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, Indiana 46285, USA
    Br J Psychiatry 184:337-45. 2004
  5. ncbi request reprint Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study
    Mauricio Tohen
    Lilly Research Laboratories, IN 46285, USA
    Am J Psychiatry 160:1263-71. 2003
  6. ncbi request reprint Clinical relevance of depressive symptom improvement in bipolar I depressed patients
    Doug Williamson
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46221, USA
    J Affect Disord 92:261-6. 2006
  7. ncbi request reprint Olanzapine versus lithium in the maintenance treatment of bipolar disorder: a 12-month, randomized, double-blind, controlled clinical trial
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Am J Psychiatry 162:1281-90. 2005
  8. ncbi request reprint Initial symptoms of manic relapse in manic or mixed-manic bipolar disorder: post hoc analysis of patients treated with olanzapine or lithium
    John P Houston
    Lilly Corporate Center, Lilly Research Laboratories, Drop Code 4133, Indianapolis, IN 46285, United States
    J Psychiatr Res 41:616-21. 2007
  9. ncbi request reprint Randomized, placebo-controlled trial of olanzapine as maintenance therapy in patients with bipolar I disorder responding to acute treatment with olanzapine
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Am J Psychiatry 163:247-56. 2006
  10. ncbi request reprint Acute dysphoric mania: treatment response to olanzapine versus placebo
    Robert W Baker
    Lilly Research Laboratories, Indianapolis, Indiana 46285, USA
    J Clin Psychopharmacol 23:132-7. 2003

Collaborators

Detail Information

Publications30

  1. pmc Clinical, functional, and economic ramifications of early nonresponse to antipsychotics in the naturalistic treatment of schizophrenia
    Haya Ascher-Svanum
    Eli Lilly and Company, Indianapolis, IN 46285, USA
    Schizophr Bull 34:1163-71. 2008
    ..This study assessed the predictive accuracy of early nonresponse to treatment and its clinical, functional, and economic ramifications in the naturalistic treatment of predominately chronic outpatients treated for schizophrenia...
  2. ncbi request reprint Efficacy of olanzapine combined with valproate or lithium in the treatment of dysphoric mania
    Robert W Baker
    Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Br J Psychiatry 185:472-8. 2004
    ..Few controlled studies examine the treatment of depressive features in mania...
  3. ncbi request reprint Effectiveness of rapid initial dose escalation of up to forty milligrams per day of oral olanzapine in acute agitation
    Robert W Baker
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285
    J Clin Psychopharmacol 23:342-8. 2003
    ..Rapid assessment and effective treatment are necessary to manage agitation and, potentially, to shorten the time to recovery...
  4. ncbi request reprint Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, Indiana 46285, USA
    Br J Psychiatry 184:337-45. 2004
    ..Aims To evaluate whether olanzapine plus either lithium or valproate reduces the rate of relapse, compared with lithium or valproate alone...
  5. ncbi request reprint Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study
    Mauricio Tohen
    Lilly Research Laboratories, IN 46285, USA
    Am J Psychiatry 160:1263-71. 2003
    ..Few double-blind trials have compared longer-term efficacy and safety of medications for bipolar disorder. The authors report a 47-week comparison of olanzapine and divalproex...
  6. ncbi request reprint Clinical relevance of depressive symptom improvement in bipolar I depressed patients
    Doug Williamson
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46221, USA
    J Affect Disord 92:261-6. 2006
    ..Gaps remain between rating scale changes obtained in a clinical trial and what those results mean in clinical practice...
  7. ncbi request reprint Olanzapine versus lithium in the maintenance treatment of bipolar disorder: a 12-month, randomized, double-blind, controlled clinical trial
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Am J Psychiatry 162:1281-90. 2005
    ..The authors compared the efficacy of olanzapine and lithium in the prevention of mood episode relapse/recurrence...
  8. ncbi request reprint Initial symptoms of manic relapse in manic or mixed-manic bipolar disorder: post hoc analysis of patients treated with olanzapine or lithium
    John P Houston
    Lilly Corporate Center, Lilly Research Laboratories, Drop Code 4133, Indianapolis, IN 46285, United States
    J Psychiatr Res 41:616-21. 2007
    ....
  9. ncbi request reprint Randomized, placebo-controlled trial of olanzapine as maintenance therapy in patients with bipolar I disorder responding to acute treatment with olanzapine
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Am J Psychiatry 163:247-56. 2006
    ..In a placebo-controlled, double-blind study, the authors investigated the efficacy and safety of olanzapine as monotherapy in relapse prevention in bipolar I disorder...
  10. ncbi request reprint Acute dysphoric mania: treatment response to olanzapine versus placebo
    Robert W Baker
    Lilly Research Laboratories, Indianapolis, Indiana 46285, USA
    J Clin Psychopharmacol 23:132-7. 2003
    ..Additional experience with putative mood stabilizers and atypical agents in mixed mania should include an exploration of their efficacy in treating both manic and depressive mood symptoms...
  11. ncbi request reprint A 12-week, double-blind comparison of olanzapine vs haloperidol in the treatment of acute mania
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, Ind 46225, USA
    Arch Gen Psychiatry 60:1218-26. 2003
    ..This randomized controlled trial compares the efficacy and safety of olanzapine vs haloperidol, as well as the quality of life of patients taking these drugs, in patients with bipolar mania...
  12. ncbi request reprint Olanzapine versus divalproex in the treatment of acute mania
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Am J Psychiatry 159:1011-7. 2002
    ..The effects of olanzapine and divalproex for the treatment of mania were compared in a large randomized clinical trial...
  13. ncbi request reprint Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression
    Mauricio Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Arch Gen Psychiatry 60:1079-88. 2003
    ....
  14. ncbi request reprint Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy
    Mauricio Tohen
    Lilly Research Laboratories, Eli Lilly and Co, Indianapolis, IN 46285, USA
    Arch Gen Psychiatry 59:62-9. 2002
    ....
  15. ncbi request reprint Placebo-controlled trials do not find association of olanzapine with exacerbation of bipolar mania
    Robert W Baker
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Drop Code 4133, Indianapolis, IN 46285, USA
    J Affect Disord 73:147-53. 2003
    ..Presumably, bipolar patients would be at increased risk for this putative adverse event. Therefore, we evaluated the potential of olanzapine to exacerbate symptoms of mania compared to placebo during treatment of bipolar mania...
  16. ncbi request reprint Service utilization and costs of olanzapine versus divalproex treatment for acute mania: results from a randomized, 47-week clinical trial
    Baojin Zhu
    Lilly Research Laboratories, Indianapolis, IN, USA
    Curr Med Res Opin 21:555-64. 2005
    ....
  17. ncbi request reprint Effects of olanzapine alone and olanzapine/fluoxetine combination on health-related quality of life in patients with bipolar depression: secondary analyses of a double-blind, placebo-controlled, randomized clinical trial
    Lizheng Shi
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA
    Clin Ther 26:125-34. 2004
    ..Improving patients' health-related quality of life (HRQOL) could be a treatment goal for bipolar depression...
  18. ncbi request reprint The impact of response to previous mood stabilizer therapy on response to olanzapine versus placebo for acute mania
    Robert W Baker
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Bipolar Disord 4:43-9. 2002
    ..In this secondary analysis of a placebo-controlled trial demonstrating olanzapine's efficacy for acute mania, we explore whether its usefulness extends to those patients with a history of poor response to other mood stabilizers...
  19. ncbi request reprint Longitudinal effect of olanzapine on fasting serum lipids: a randomized, prospective, 4-month study
    Bruce J Kinon
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Drop Code 4133, Indianapolis, IN 46285, USA
    Ann N Y Acad Sci 1032:295-6. 2004
    ....
  20. ncbi request reprint Retrospective analysis of diabetes risk in elderly patients with dementia in olanzapine clinical trials
    Joseph L Micca
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Am J Geriatr Psychiatry 14:62-70. 2006
    ..The objective of this study was to evaluate the association of established risk factors for treatment-emergent diabetes (TED) among patients over 65 years of age with dementia who received treatment with olanzapine...
  21. ncbi request reprint Olanzapine versus placebo in acute mania: treatment responses in subgroups
    Ross J Baldessarini
    International Consortium for Bipolar Disorder Research, Department of Psychiatry and Neuroscience Program, Harvard Medical School, Boston, MA, USA
    J Clin Psychopharmacol 23:370-6. 2003
    ..5-1.7, all P < 0.01). These well-powered comparisons of subgroups of interest indicate broad efficacy of olanzapine in the treatment of acute mania...
  22. ncbi request reprint Outcomes for Latin American versus White patients suffering from acute mania in a randomized, double-blind trial comparing olanzapine and haloperidol
    Jorge M Tamayo
    Department of Psychiatry, CES University, Medellin, Colombia
    J Clin Psychopharmacol 27:126-34. 2007
    ..The pattern of adverse events differed between treatment groups. Prospective clinical trials in Latin American bipolar populations are justified...
  23. ncbi request reprint Olanzapine versus risperidone in the treatment of manic or mixed States in bipolar I disorder: a randomized, double-blind trial
    Roy H Perlis
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 67:1747-53. 2006
    ..To compare olanzapine and risperidone in the treatment of nonpsychotic acute manic or mixed episodes...
  24. ncbi request reprint Comments to the editor on "Outcomes and costs of risperidone versus olanzapine in patients with chronic schizophrenia or schizoaffective disorders: a Markov model"
    Jerry D Clewell
    Value Health 8:175-6. 2005
  25. ncbi request reprint Rates of response, euthymia and remission in two placebo-controlled olanzapine trials for bipolar mania
    K N Roy Chengappa
    Western Psychiatric Institute and Clinic, Mayview State Hospital, University of Pittsburgh Medical Center, PA 15213 2593, USA
    Bipolar Disord 5:1-5. 2003
    ....
  26. ncbi request reprint Clinical features of bipolar depression versus major depressive disorder in large multicenter trials
    Roy H Perlis
    Massachusetts General Hospital, ACC 812, 15 Parkman Street, Boston, MA 02114, USA
    Am J Psychiatry 163:225-31. 2006
    ..Clinical features that could distinguish bipolar from unipolar depression would facilitate more appropriate treatment selection...
  27. ncbi request reprint An excitement subscale of the Positive and Negative Syndrome Scale
    Jean Pierre Lindenmayer
    Department of Psychiatry, New York University School of Medicine, and Manhattan Psychiatric Center, Wards Island Complex, New York, NY, USA
    Schizophr Res 68:331-7. 2004
    ....
  28. ncbi request reprint Rapid versus non-rapid cycling as a predictor of response to olanzapine and divalproex sodium for bipolar mania and maintenance of remission: post hoc analyses of 47-week data
    Trisha Suppes
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9121, United States
    J Affect Disord 89:69-77. 2005
    ..Rapid cycling in bipolar disorder has been associated with greater morbidity. We examine whether rapid cycling affects treatment response to olanzapine or divalproex in acute mania...
  29. ncbi request reprint Olanzapine does not enhance cognition in non-agitated and non-psychotic patients with mild to moderate Alzheimer's dementia
    John Kennedy
    University of Alberta and Chinook Regional Health System, Alberta, Canada
    Int J Geriatr Psychiatry 20:1020-7. 2005
    ..This was an exploratory study of olanzapine as potential treatment for improvement in cognition in patients with Alzheimer's disease without prominent psychobehavioral symptoms...
  30. ncbi request reprint Recovery and functional outcomes following olanzapine treatment for bipolar I mania
    K N Roy Chengappa
    Western Psychiatric Institute and Clinic, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213 2593, USA
    Bipolar Disord 7:68-76. 2005
    ..Typical experimental categorizations of treatment responses in bipolar disorder (BPD) patients may have limited relationship to clinical recovery or functional status, and there is inadequate research on such clinically important outcomes...