J Michael Bradshaw

Summary

Affiliation: Elan Pharmaceuticals
Country: USA

Publications

  1. doi The Src, Syk, and Tec family kinases: distinct types of molecular switches
    J Michael Bradshaw
    Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304, United States
    Cell Signal 22:1175-84. 2010
  2. ncbi Steady state kinetics of spleen tyrosine kinase investigated by a real time fluorescence assay
    Eva Papp
    Department of Biochemical Pharmacology, Roche Palo Alto LLC, 3431 Hillview Avenue, Palo Alto, California 94304, USA
    Biochemistry 46:15103-14. 2007

Collaborators

  • Eva Papp
  • Hoangdung Ho
  • Joyce K Y Tse
  • Simon Lee
  • Sandra Wang
  • Jim Barnett
  • David C Swinney
  • David Shaw

Detail Information

Publications2

  1. doi The Src, Syk, and Tec family kinases: distinct types of molecular switches
    J Michael Bradshaw
    Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304, United States
    Cell Signal 22:1175-84. 2010
    ..The multiple factors that regulate the Src, Syk, and Tec families illustrate the important role played by each of these kinases in immune cell signaling...
  2. ncbi Steady state kinetics of spleen tyrosine kinase investigated by a real time fluorescence assay
    Eva Papp
    Department of Biochemical Pharmacology, Roche Palo Alto LLC, 3431 Hillview Avenue, Palo Alto, California 94304, USA
    Biochemistry 46:15103-14. 2007
    ..The findings presented here provide the first kinetic description of the Syk enzyme mechanism...